Eric Topol
@erictopol.bsky.social
physician-scientist, author, editor
https://www.scripps.edu/faculty/topol/
Ground Truths https://erictopol.substack.com
SUPER AGERS https://www.simonandschuster.com/books/Super-Agers/Eric-Topol/9781668067666
https://www.scripps.edu/faculty/topol/
Ground Truths https://erictopol.substack.com
SUPER AGERS https://www.simonandschuster.com/books/Super-Agers/Eric-Topol/9781668067666
Pinned
Eric Topol
@erictopol.bsky.social
· May 27
A new cover for SUPER AGERS after making the NYT bestseller list. Thanks to you for making it the #1 ranked new non-fiction book on Amazon.
amazon.com/gp/new-relea...
amazon.com/gp/new-relea...
Reposted by Eric Topol
KPBS: 'Scientists launch new trial for long COVID treatment'
Eric Topol: "They can't work..function..have a hard time just getting out of bed...the first of trials we hope to move forward with..there are so many other potential candidate drugs interventions to help..."
www.kpbs.org/podcasts/kpb...
Eric Topol: "They can't work..function..have a hard time just getting out of bed...the first of trials we hope to move forward with..there are so many other potential candidate drugs interventions to help..."
www.kpbs.org/podcasts/kpb...
Scientists launch new trial for long COVID treatment
Launched by the Scripps Research Translational Institute, the trial will test a repurposed GLP-1 drug, tirzepatide, and if it can provide relief for long COVID symptoms.
www.kpbs.org
November 11, 2025 at 12:52 AM
KPBS: 'Scientists launch new trial for long COVID treatment'
Eric Topol: "They can't work..function..have a hard time just getting out of bed...the first of trials we hope to move forward with..there are so many other potential candidate drugs interventions to help..."
www.kpbs.org/podcasts/kpb...
Eric Topol: "They can't work..function..have a hard time just getting out of bed...the first of trials we hope to move forward with..there are so many other potential candidate drugs interventions to help..."
www.kpbs.org/podcasts/kpb...
2 #LongCovid randomized trials published today
—Online cognitive training, negative
jamanetwork.com/journals/jam...
—Resistance training, modest benefit
jamanetwork.com/journals/jam...
—Online cognitive training, negative
jamanetwork.com/journals/jam...
—Resistance training, modest benefit
jamanetwork.com/journals/jam...
November 10, 2025 at 8:50 PM
2 #LongCovid randomized trials published today
—Online cognitive training, negative
jamanetwork.com/journals/jam...
—Resistance training, modest benefit
jamanetwork.com/journals/jam...
—Online cognitive training, negative
jamanetwork.com/journals/jam...
—Resistance training, modest benefit
jamanetwork.com/journals/jam...
Reposted by Eric Topol
Take a 13 min break for an interesting discussion on the potential impact of COVID mRNA vaccines on cancer treatments & cancer patients.
Ira talks with Adam Grippin (@mdanderson.bsky.social) and @erictopol.bsky.social (The Scripps Research Inst.).
www.sciencefriday.com/segments/cov...
Ira talks with Adam Grippin (@mdanderson.bsky.social) and @erictopol.bsky.social (The Scripps Research Inst.).
www.sciencefriday.com/segments/cov...
Study Finds COVID mRNA Vaccines Boost Cancer Treatment
New research found that mRNA vaccines for COVID-19 could enhance cancer treatments and help patients live longer.
www.sciencefriday.com
November 10, 2025 at 7:12 PM
Take a 13 min break for an interesting discussion on the potential impact of COVID mRNA vaccines on cancer treatments & cancer patients.
Ira talks with Adam Grippin (@mdanderson.bsky.social) and @erictopol.bsky.social (The Scripps Research Inst.).
www.sciencefriday.com/segments/cov...
Ira talks with Adam Grippin (@mdanderson.bsky.social) and @erictopol.bsky.social (The Scripps Research Inst.).
www.sciencefriday.com/segments/cov...
I'm struck by the vision and leadership that Dr. Susan Monarez could have provided for the CDC. Her remarkable resilience, in spite of what she has been through, is inspiring.
Our conversation: erictopol.substack.com/p/dr-susan-m... and a clip from it here
Our conversation: erictopol.substack.com/p/dr-susan-m... and a clip from it here
November 10, 2025 at 6:54 PM
I'm struck by the vision and leadership that Dr. Susan Monarez could have provided for the CDC. Her remarkable resilience, in spite of what she has been through, is inspiring.
Our conversation: erictopol.substack.com/p/dr-susan-m... and a clip from it here
Our conversation: erictopol.substack.com/p/dr-susan-m... and a clip from it here
The heath benefits of multilingualism appear to be far beyond prior expectations
erictopol.substack.com/p/multilingu...
erictopol.substack.com/p/multilingu...
Multilingualism and Extending Healthspan
Evidence for a new independent lifestyle factor linked to healthy aging
erictopol.substack.com
November 10, 2025 at 4:08 PM
The heath benefits of multilingualism appear to be far beyond prior expectations
erictopol.substack.com/p/multilingu...
erictopol.substack.com/p/multilingu...
No clear evidence to support any link between maternal acetaminophen (Tylenol) intake and autism or ADHD in offspring, a new umbrella, systematic review
@bmj.com
@bmj.com
November 10, 2025 at 12:19 AM
No clear evidence to support any link between maternal acetaminophen (Tylenol) intake and autism or ADHD in offspring, a new umbrella, systematic review
@bmj.com
@bmj.com
Delusional thinking about healthspan and longevity, now from China
"In 5 to 10 years nobody will get cancer."
"Living to 150 is definitely realistic. In a few years this will be the reality."
www.nytimes.com/2025/11/08/w...
"In 5 to 10 years nobody will get cancer."
"Living to 150 is definitely realistic. In a few years this will be the reality."
www.nytimes.com/2025/11/08/w...
In China, the Dream of Outrunning Time
www.nytimes.com
November 9, 2025 at 3:39 PM
Delusional thinking about healthspan and longevity, now from China
"In 5 to 10 years nobody will get cancer."
"Living to 150 is definitely realistic. In a few years this will be the reality."
www.nytimes.com/2025/11/08/w...
"In 5 to 10 years nobody will get cancer."
"Living to 150 is definitely realistic. In a few years this will be the reality."
www.nytimes.com/2025/11/08/w...
Get this: Coffee suppressed atrial fibrillation!
Unexpected results for recurrence from a randomized trial in participants after cardioversion from AF
#AHA25 @jama.com
jamanetwork.com/journals/jam...
Unexpected results for recurrence from a randomized trial in participants after cardioversion from AF
#AHA25 @jama.com
jamanetwork.com/journals/jam...
November 9, 2025 at 2:51 PM
Get this: Coffee suppressed atrial fibrillation!
Unexpected results for recurrence from a randomized trial in participants after cardioversion from AF
#AHA25 @jama.com
jamanetwork.com/journals/jam...
Unexpected results for recurrence from a randomized trial in participants after cardioversion from AF
#AHA25 @jama.com
jamanetwork.com/journals/jam...
My interview with Dr. Susan Monarez, former CDC Director, who was fired for doing her job, standing up for public health and science. Learn about her resilience and optimism.
erictopol.substack.com/p/dr-susan-m...
erictopol.substack.com/p/dr-susan-m...
Dr. Susan Monarez—Former CDC Director, First Live Interview
An American hero for standing up for science and public health
erictopol.substack.com
November 8, 2025 at 4:06 PM
My interview with Dr. Susan Monarez, former CDC Director, who was fired for doing her job, standing up for public health and science. Learn about her resilience and optimism.
erictopol.substack.com/p/dr-susan-m...
erictopol.substack.com/p/dr-susan-m...
The dysregulated immune system in #LongCovid with #MECFS. with sex-specific changes, increased inflammation (as seen by cells, chemokines and cytokines), and disrupted hormone levels www.cell.com/cell-reports...
November 7, 2025 at 4:00 PM
The dysregulated immune system in #LongCovid with #MECFS. with sex-specific changes, increased inflammation (as seen by cells, chemokines and cytokines), and disrupted hormone levels www.cell.com/cell-reports...
Ozempic and Zepbound are just the beginning of the expanded medical GI hormone era. A new selective amylin mimetic (pancreatic peptide)) achieved marked weight loss and reduced inflammation without a plateau effect in a randomized trial
@thelancet.com
thelancet.com/journals/lan...
@thelancet.com
thelancet.com/journals/lan...
November 7, 2025 at 2:24 PM
Ozempic and Zepbound are just the beginning of the expanded medical GI hormone era. A new selective amylin mimetic (pancreatic peptide)) achieved marked weight loss and reduced inflammation without a plateau effect in a randomized trial
@thelancet.com
thelancet.com/journals/lan...
@thelancet.com
thelancet.com/journals/lan...
The prisoner’s dilemma in A.I. healthcare—
when rational A.I. use can lead to harmful outcomes
Our new piece @thelancet.com
@rajpurkar.bsky.social and Michael Moritz
thelancet.com/journals/lan...
when rational A.I. use can lead to harmful outcomes
Our new piece @thelancet.com
@rajpurkar.bsky.social and Michael Moritz
thelancet.com/journals/lan...
Coordinating health AI to prevent defensive escalation
Artificial intelligence (AI) systems that can analyse medical images, records, and
claims are becoming accessible to everyone. Although these systems outperform physicians
at specific tasks, such as d...
thelancet.com
November 7, 2025 at 12:14 AM
The prisoner’s dilemma in A.I. healthcare—
when rational A.I. use can lead to harmful outcomes
Our new piece @thelancet.com
@rajpurkar.bsky.social and Michael Moritz
thelancet.com/journals/lan...
when rational A.I. use can lead to harmful outcomes
Our new piece @thelancet.com
@rajpurkar.bsky.social and Michael Moritz
thelancet.com/journals/lan...
The rise in US health care costs related to more treatment
www.economist.com/united-state...
www.economist.com/united-state...
November 6, 2025 at 5:30 PM
The rise in US health care costs related to more treatment
www.economist.com/united-state...
www.economist.com/united-state...
Reposted by Eric Topol
With the help of @statto.bsky.social and @erictopol.bsky.social (🙏) I have delved a little into the often bizarre efforts of tech billionairres to live forever. Is there anything at all in it? My column for @thenewworldmag.bsky.social
www.thenewworld.co.uk/philip-ball-...
www.thenewworld.co.uk/philip-ball-...
The tech lords' quest for eternal life
Nothing is more transparent than Silicon Valley’s fixation with longevity and, ideally, immortality, revealing a desperate fear of death
www.thenewworld.co.uk
November 6, 2025 at 5:08 PM
With the help of @statto.bsky.social and @erictopol.bsky.social (🙏) I have delved a little into the often bizarre efforts of tech billionairres to live forever. Is there anything at all in it? My column for @thenewworldmag.bsky.social
www.thenewworld.co.uk/philip-ball-...
www.thenewworld.co.uk/philip-ball-...
On Ground Truths, I'll be talking with Dr. Susan Monarez today, her first interview since leaving her post as CDC Director
1 PM PT (4 PM ET)
Join us, subscribe (it's free) erictopol.substack.com
1 PM PT (4 PM ET)
Join us, subscribe (it's free) erictopol.substack.com
Ground Truths | Eric Topol | Substack
Facts, data and analytics about biomedical matters. Click to read Ground Truths, by Eric Topol, a Substack publication with hundreds of thousands of subscribers.
erictopol.substack.com
November 6, 2025 at 2:49 PM
On Ground Truths, I'll be talking with Dr. Susan Monarez today, her first interview since leaving her post as CDC Director
1 PM PT (4 PM ET)
Join us, subscribe (it's free) erictopol.substack.com
1 PM PT (4 PM ET)
Join us, subscribe (it's free) erictopol.substack.com
The inside story of COVAX, started in January 2020, and led to 2 billion doses of Covid vaccines given in 146 countries, with 2.7 million lives saved. FAIR DOSES, by
@drsethberkley.bsky.social
A clip from our Ground Truths conversation today
Link to full: erictopol.substack.com/p/seth-berkl...
@drsethberkley.bsky.social
A clip from our Ground Truths conversation today
Link to full: erictopol.substack.com/p/seth-berkl...
November 5, 2025 at 6:44 PM
The inside story of COVAX, started in January 2020, and led to 2 billion doses of Covid vaccines given in 146 countries, with 2.7 million lives saved. FAIR DOSES, by
@drsethberkley.bsky.social
A clip from our Ground Truths conversation today
Link to full: erictopol.substack.com/p/seth-berkl...
@drsethberkley.bsky.social
A clip from our Ground Truths conversation today
Link to full: erictopol.substack.com/p/seth-berkl...
For children and teens, heart and blood vessel complications of Covid overshadow the very rare and short-term risk of vaccinations, a new report from nearly 14 million kids
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
November 5, 2025 at 12:48 AM
For children and teens, heart and blood vessel complications of Covid overshadow the very rare and short-term risk of vaccinations, a new report from nearly 14 million kids
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
Aging biomarkers for prediction of diseases, a systematic review of 39 biomarkers in >20,000 people. GrimAge2 best for healhspan prediction
nature.com/articles/s43...
nature.com/articles/s43...
November 4, 2025 at 4:28 PM
Aging biomarkers for prediction of diseases, a systematic review of 39 biomarkers in >20,000 people. GrimAge2 best for healhspan prediction
nature.com/articles/s43...
nature.com/articles/s43...
Many clinical studies have shown reduced cancer risk in people with diabetes of obesity taking GLP-1 family of drugs. A new JCI piece makes the case these drugs should be studied to reduce cancer in people without metabolic disease jci.org/articles/vie...
November 3, 2025 at 7:08 PM
Many clinical studies have shown reduced cancer risk in people with diabetes of obesity taking GLP-1 family of drugs. A new JCI piece makes the case these drugs should be studied to reduce cancer in people without metabolic disease jci.org/articles/vie...
GLP-1 drugs have intrinsic potent anti-inflammatory action beyond their metabolic beneficial impact on glucose regulation and weight loss
www.jci.org/articles/vie...
www.jci.org/articles/vie...
November 3, 2025 at 5:20 PM
GLP-1 drugs have intrinsic potent anti-inflammatory action beyond their metabolic beneficial impact on glucose regulation and weight loss
www.jci.org/articles/vie...
www.jci.org/articles/vie...
Join Lee Hood and I for a conversation about Super Agers, tomorrow 10 AM PT isbscience.zoom.us/webinar/regi...
November 3, 2025 at 4:50 PM
Join Lee Hood and I for a conversation about Super Agers, tomorrow 10 AM PT isbscience.zoom.us/webinar/regi...
Physical activity and risk of Alzheimer's disease.
In older adults (mean age 72) with elevated Aβ amyloid, 5,000-7,500 steps/day (<-a plateau) were associated with less Tau accumulation, improved cognition
@naturemedicine.bsky.social
nature.com/articles/s41...
In older adults (mean age 72) with elevated Aβ amyloid, 5,000-7,500 steps/day (<-a plateau) were associated with less Tau accumulation, improved cognition
@naturemedicine.bsky.social
nature.com/articles/s41...
November 3, 2025 at 4:09 PM
Physical activity and risk of Alzheimer's disease.
In older adults (mean age 72) with elevated Aβ amyloid, 5,000-7,500 steps/day (<-a plateau) were associated with less Tau accumulation, improved cognition
@naturemedicine.bsky.social
nature.com/articles/s41...
In older adults (mean age 72) with elevated Aβ amyloid, 5,000-7,500 steps/day (<-a plateau) were associated with less Tau accumulation, improved cognition
@naturemedicine.bsky.social
nature.com/articles/s41...
Good and accurate summary of data for creatine supplements wapo.st/4nGIHSt
Column | As a doctor, here’s my advice on creatine supplements
Creatine may make you stronger — but only if you meet certain criteria.
wapo.st
November 3, 2025 at 3:12 PM
Good and accurate summary of data for creatine supplements wapo.st/4nGIHSt
A word that has become a euphemism for promoting and selling things without data or evidence
November 2, 2025 at 6:19 PM
A word that has become a euphemism for promoting and selling things without data or evidence
This week's @nature.com cover highlights a report of A.I.- mediated distortion
When #ChatGPT was asked to rate 40,000 résumés, it ranked the older male candidates as better quality than the younger female applicants nature.com/articles/s41...
When #ChatGPT was asked to rate 40,000 résumés, it ranked the older male candidates as better quality than the younger female applicants nature.com/articles/s41...
November 2, 2025 at 6:12 PM
This week's @nature.com cover highlights a report of A.I.- mediated distortion
When #ChatGPT was asked to rate 40,000 résumés, it ranked the older male candidates as better quality than the younger female applicants nature.com/articles/s41...
When #ChatGPT was asked to rate 40,000 résumés, it ranked the older male candidates as better quality than the younger female applicants nature.com/articles/s41...