Eric Topol
@erictopol.bsky.social
physician-scientist, author, editor
https://www.scripps.edu/faculty/topol/
Ground Truths https://erictopol.substack.com
SUPER AGERS https://www.simonandschuster.com/books/Super-Agers/Eric-Topol/9781668067666
https://www.scripps.edu/faculty/topol/
Ground Truths https://erictopol.substack.com
SUPER AGERS https://www.simonandschuster.com/books/Super-Agers/Eric-Topol/9781668067666
2 #LongCovid randomized trials published today
—Online cognitive training, negative
jamanetwork.com/journals/jam...
—Resistance training, modest benefit
jamanetwork.com/journals/jam...
—Online cognitive training, negative
jamanetwork.com/journals/jam...
—Resistance training, modest benefit
jamanetwork.com/journals/jam...
November 10, 2025 at 8:50 PM
2 #LongCovid randomized trials published today
—Online cognitive training, negative
jamanetwork.com/journals/jam...
—Resistance training, modest benefit
jamanetwork.com/journals/jam...
—Online cognitive training, negative
jamanetwork.com/journals/jam...
—Resistance training, modest benefit
jamanetwork.com/journals/jam...
I'm struck by the vision and leadership that Dr. Susan Monarez could have provided for the CDC. Her remarkable resilience, in spite of what she has been through, is inspiring.
Our conversation: erictopol.substack.com/p/dr-susan-m... and a clip from it here
Our conversation: erictopol.substack.com/p/dr-susan-m... and a clip from it here
November 10, 2025 at 6:54 PM
I'm struck by the vision and leadership that Dr. Susan Monarez could have provided for the CDC. Her remarkable resilience, in spite of what she has been through, is inspiring.
Our conversation: erictopol.substack.com/p/dr-susan-m... and a clip from it here
Our conversation: erictopol.substack.com/p/dr-susan-m... and a clip from it here
Here's the Table summarizing the key flaws and why there's lack of confidence in any report
November 10, 2025 at 12:20 AM
Here's the Table summarizing the key flaws and why there's lack of confidence in any report
No clear evidence to support any link between maternal acetaminophen (Tylenol) intake and autism or ADHD in offspring, a new umbrella, systematic review
@bmj.com
@bmj.com
November 10, 2025 at 12:19 AM
No clear evidence to support any link between maternal acetaminophen (Tylenol) intake and autism or ADHD in offspring, a new umbrella, systematic review
@bmj.com
@bmj.com
visual abstract of the trial and results
November 9, 2025 at 3:49 PM
visual abstract of the trial and results
Get this: Coffee suppressed atrial fibrillation!
Unexpected results for recurrence from a randomized trial in participants after cardioversion from AF
#AHA25 @jama.com
jamanetwork.com/journals/jam...
Unexpected results for recurrence from a randomized trial in participants after cardioversion from AF
#AHA25 @jama.com
jamanetwork.com/journals/jam...
November 9, 2025 at 2:51 PM
Get this: Coffee suppressed atrial fibrillation!
Unexpected results for recurrence from a randomized trial in participants after cardioversion from AF
#AHA25 @jama.com
jamanetwork.com/journals/jam...
Unexpected results for recurrence from a randomized trial in participants after cardioversion from AF
#AHA25 @jama.com
jamanetwork.com/journals/jam...
The Shooting at CDC
November 8, 2025 at 6:04 PM
The Shooting at CDC
Dismantling the CDC
November 8, 2025 at 4:50 PM
Dismantling the CDC
The dysregulated immune system in #LongCovid with #MECFS. with sex-specific changes, increased inflammation (as seen by cells, chemokines and cytokines), and disrupted hormone levels www.cell.com/cell-reports...
November 7, 2025 at 4:00 PM
The dysregulated immune system in #LongCovid with #MECFS. with sex-specific changes, increased inflammation (as seen by cells, chemokines and cytokines), and disrupted hormone levels www.cell.com/cell-reports...
Ozempic and Zepbound are just the beginning of the expanded medical GI hormone era. A new selective amylin mimetic (pancreatic peptide)) achieved marked weight loss and reduced inflammation without a plateau effect in a randomized trial
@thelancet.com
thelancet.com/journals/lan...
@thelancet.com
thelancet.com/journals/lan...
November 7, 2025 at 2:24 PM
Ozempic and Zepbound are just the beginning of the expanded medical GI hormone era. A new selective amylin mimetic (pancreatic peptide)) achieved marked weight loss and reduced inflammation without a plateau effect in a randomized trial
@thelancet.com
thelancet.com/journals/lan...
@thelancet.com
thelancet.com/journals/lan...
The rise in US health care costs related to more treatment
www.economist.com/united-state...
www.economist.com/united-state...
November 6, 2025 at 5:30 PM
The rise in US health care costs related to more treatment
www.economist.com/united-state...
www.economist.com/united-state...
A @WSJ oped today on this advance vs cancer www.wsj.com/opinion/oper...
November 6, 2025 at 1:37 PM
A @WSJ oped today on this advance vs cancer www.wsj.com/opinion/oper...
How mRNA vaccines helped patients fight vs cancer
Recent Ground Truths on this important topic erictopol.substack.com/p/how-mrna-v...
Recent Ground Truths on this important topic erictopol.substack.com/p/how-mrna-v...
November 5, 2025 at 6:52 PM
How mRNA vaccines helped patients fight vs cancer
Recent Ground Truths on this important topic erictopol.substack.com/p/how-mrna-v...
Recent Ground Truths on this important topic erictopol.substack.com/p/how-mrna-v...
why killing mRNA vaccine research is dangerous
November 5, 2025 at 6:48 PM
why killing mRNA vaccine research is dangerous
The inside story of COVAX, started in January 2020, and led to 2 billion doses of Covid vaccines given in 146 countries, with 2.7 million lives saved. FAIR DOSES, by
@drsethberkley.bsky.social
A clip from our Ground Truths conversation today
Link to full: erictopol.substack.com/p/seth-berkl...
@drsethberkley.bsky.social
A clip from our Ground Truths conversation today
Link to full: erictopol.substack.com/p/seth-berkl...
November 5, 2025 at 6:44 PM
The inside story of COVAX, started in January 2020, and led to 2 billion doses of Covid vaccines given in 146 countries, with 2.7 million lives saved. FAIR DOSES, by
@drsethberkley.bsky.social
A clip from our Ground Truths conversation today
Link to full: erictopol.substack.com/p/seth-berkl...
@drsethberkley.bsky.social
A clip from our Ground Truths conversation today
Link to full: erictopol.substack.com/p/seth-berkl...
For children and teens, heart and blood vessel complications of Covid overshadow the very rare and short-term risk of vaccinations, a new report from nearly 14 million kids
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
November 5, 2025 at 12:48 AM
For children and teens, heart and blood vessel complications of Covid overshadow the very rare and short-term risk of vaccinations, a new report from nearly 14 million kids
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
Aging biomarkers for prediction of diseases, a systematic review of 39 biomarkers in >20,000 people. GrimAge2 best for healhspan prediction
nature.com/articles/s43...
nature.com/articles/s43...
November 4, 2025 at 4:28 PM
Aging biomarkers for prediction of diseases, a systematic review of 39 biomarkers in >20,000 people. GrimAge2 best for healhspan prediction
nature.com/articles/s43...
nature.com/articles/s43...
Many clinical studies have shown reduced cancer risk in people with diabetes of obesity taking GLP-1 family of drugs. A new JCI piece makes the case these drugs should be studied to reduce cancer in people without metabolic disease jci.org/articles/vie...
November 3, 2025 at 7:08 PM
Many clinical studies have shown reduced cancer risk in people with diabetes of obesity taking GLP-1 family of drugs. A new JCI piece makes the case these drugs should be studied to reduce cancer in people without metabolic disease jci.org/articles/vie...
GLP-1 drugs have intrinsic potent anti-inflammatory action beyond their metabolic beneficial impact on glucose regulation and weight loss
www.jci.org/articles/vie...
www.jci.org/articles/vie...
November 3, 2025 at 5:20 PM
GLP-1 drugs have intrinsic potent anti-inflammatory action beyond their metabolic beneficial impact on glucose regulation and weight loss
www.jci.org/articles/vie...
www.jci.org/articles/vie...
Join Lee Hood and I for a conversation about Super Agers, tomorrow 10 AM PT isbscience.zoom.us/webinar/regi...
November 3, 2025 at 4:50 PM
Join Lee Hood and I for a conversation about Super Agers, tomorrow 10 AM PT isbscience.zoom.us/webinar/regi...
Physical activity and risk of Alzheimer's disease.
In older adults (mean age 72) with elevated Aβ amyloid, 5,000-7,500 steps/day (<-a plateau) were associated with less Tau accumulation, improved cognition
@naturemedicine.bsky.social
nature.com/articles/s41...
In older adults (mean age 72) with elevated Aβ amyloid, 5,000-7,500 steps/day (<-a plateau) were associated with less Tau accumulation, improved cognition
@naturemedicine.bsky.social
nature.com/articles/s41...
November 3, 2025 at 4:09 PM
Physical activity and risk of Alzheimer's disease.
In older adults (mean age 72) with elevated Aβ amyloid, 5,000-7,500 steps/day (<-a plateau) were associated with less Tau accumulation, improved cognition
@naturemedicine.bsky.social
nature.com/articles/s41...
In older adults (mean age 72) with elevated Aβ amyloid, 5,000-7,500 steps/day (<-a plateau) were associated with less Tau accumulation, improved cognition
@naturemedicine.bsky.social
nature.com/articles/s41...
A word that has become a euphemism for promoting and selling things without data or evidence
November 2, 2025 at 6:19 PM
A word that has become a euphemism for promoting and selling things without data or evidence