Estefania Sanchez-Vasquez
@niasv.bsky.social
HSRU postdoctoral fellow
Pew Latin American fellow
Development & Stem cell bio
#ucsc 🌈 UNMSM 🇵🇪 UNSAM 🇦🇷
Pew Latin American fellow
Development & Stem cell bio
#ucsc 🌈 UNMSM 🇵🇪 UNSAM 🇦🇷
Reposted by Estefania Sanchez-Vasquez
Still posting cytoskeleton videos, it seems. Actin this time.
Sample: Lifeact-eGFP in HeLa cells.
Modality: Airyscan confocal
Timestamp is mm:ss and the scale bar is 5 µm.
Sample: Lifeact-eGFP in HeLa cells.
Modality: Airyscan confocal
Timestamp is mm:ss and the scale bar is 5 µm.
November 23, 2025 at 3:21 AM
Still posting cytoskeleton videos, it seems. Actin this time.
Sample: Lifeact-eGFP in HeLa cells.
Modality: Airyscan confocal
Timestamp is mm:ss and the scale bar is 5 µm.
Sample: Lifeact-eGFP in HeLa cells.
Modality: Airyscan confocal
Timestamp is mm:ss and the scale bar is 5 µm.
Reposted by Estefania Sanchez-Vasquez
Unpause! I'm super happy to now be able to share the published version of our paper at Science Advances showing that:
1) active histone mods occur independently of transcription
2) transcription coordinates histone deacetylation at active promoters
www.science.org/doi/10.1126/...
1) active histone mods occur independently of transcription
2) transcription coordinates histone deacetylation at active promoters
www.science.org/doi/10.1126/...
RNA polymerase II coordinates histone deacetylation at active promoters
Transcription initiation limits histone acetylation and H2AZ incorporation at promoters.
www.science.org
February 12, 2025 at 9:21 PM
Unpause! I'm super happy to now be able to share the published version of our paper at Science Advances showing that:
1) active histone mods occur independently of transcription
2) transcription coordinates histone deacetylation at active promoters
www.science.org/doi/10.1126/...
1) active histone mods occur independently of transcription
2) transcription coordinates histone deacetylation at active promoters
www.science.org/doi/10.1126/...
Reposted by Estefania Sanchez-Vasquez
✨ Happy to share that our work is now published in @embojournal.org ! ✨
Our fantastic collaboration between @crisprscan.bsky.social
@bazzinilab.bsky.social
Here is the updated thread (1/13):
www.embopress.org/doi/full/10....
Our fantastic collaboration between @crisprscan.bsky.social
@bazzinilab.bsky.social
Here is the updated thread (1/13):
www.embopress.org/doi/full/10....
CRISPR-RfxCas13d screening uncovers Bckdk as a post-translational regulator of maternal-to-zygotic transition in teleosts | The EMBO Journal
imageimagePost-translational regulation during the maternal-to-zygotic transition (MZT) remains
largely unexplored. Using an optimized CRISPR-RfxCas13d screening strategy, this study
identifies Bckdk ...
www.embopress.org
November 20, 2025 at 3:14 PM
✨ Happy to share that our work is now published in @embojournal.org ! ✨
Our fantastic collaboration between @crisprscan.bsky.social
@bazzinilab.bsky.social
Here is the updated thread (1/13):
www.embopress.org/doi/full/10....
Our fantastic collaboration between @crisprscan.bsky.social
@bazzinilab.bsky.social
Here is the updated thread (1/13):
www.embopress.org/doi/full/10....
Reposted by Estefania Sanchez-Vasquez
It is not often that Sialoglycoproteins and sialyltransferases are mentioned during early development. This interesting review from the lab of Katia Cailliau brings the interesting biology of sialic acid into the context of #devbio, particularly during blastula formation.
doi.org/10.1016/j.cd...
doi.org/10.1016/j.cd...
November 21, 2025 at 5:46 PM
It is not often that Sialoglycoproteins and sialyltransferases are mentioned during early development. This interesting review from the lab of Katia Cailliau brings the interesting biology of sialic acid into the context of #devbio, particularly during blastula formation.
doi.org/10.1016/j.cd...
doi.org/10.1016/j.cd...
Reposted by Estefania Sanchez-Vasquez
A new #DMMPerspective from Wenqing Xu & @aleprigio.bsky.social explores increasing evidence of #neurodevelopmental aspects in #HuntingtonsDisease & early interventions that might lead to prevention or delay of the disease pathology
journals.biologists.com/dmm/article/...
journals.biologists.com/dmm/article/...
November 21, 2025 at 7:03 PM
A new #DMMPerspective from Wenqing Xu & @aleprigio.bsky.social explores increasing evidence of #neurodevelopmental aspects in #HuntingtonsDisease & early interventions that might lead to prevention or delay of the disease pathology
journals.biologists.com/dmm/article/...
journals.biologists.com/dmm/article/...
Reposted by Estefania Sanchez-Vasquez
Neighbors! Get the scoop on what your local Nobel laureate is working on now to reveal the roots of cancer and other diseases. Our NEW "Science in the Neighborhood" public lecture series kicks off w/ UCSC's Carol Greider!
Sign up now. It's free and starts at 6pm on Dec. 11 at our coastal campus 🌊
Sign up now. It's free and starts at 6pm on Dec. 11 at our coastal campus 🌊
November 21, 2025 at 5:29 PM
Neighbors! Get the scoop on what your local Nobel laureate is working on now to reveal the roots of cancer and other diseases. Our NEW "Science in the Neighborhood" public lecture series kicks off w/ UCSC's Carol Greider!
Sign up now. It's free and starts at 6pm on Dec. 11 at our coastal campus 🌊
Sign up now. It's free and starts at 6pm on Dec. 11 at our coastal campus 🌊
Mmmmmm scary
I tried an even harder example on Gemini Pro image generation and this is quite scary/amazing. I asked for a microscopy image of around 20 HeLa cells, GFP tagged 20% nuclear, 10% membrane, +1 nuclear staining, + overlap. Image below and prompt in the following post.
November 21, 2025 at 5:39 PM
Mmmmmm scary
Reposted by Estefania Sanchez-Vasquez
Even if "provisionally" accepted, those are the best words/news I've heard for quite a while...
Here some #blebs to "provisionally" cellebrate.
Let's see this #cell dance under the microscope.
@focalplane.bsky.social #fluorescencefriday #microscopy 🧪🔬
Here some #blebs to "provisionally" cellebrate.
Let's see this #cell dance under the microscope.
@focalplane.bsky.social #fluorescencefriday #microscopy 🧪🔬
November 21, 2025 at 2:55 PM
Even if "provisionally" accepted, those are the best words/news I've heard for quite a while...
Here some #blebs to "provisionally" cellebrate.
Let's see this #cell dance under the microscope.
@focalplane.bsky.social #fluorescencefriday #microscopy 🧪🔬
Here some #blebs to "provisionally" cellebrate.
Let's see this #cell dance under the microscope.
@focalplane.bsky.social #fluorescencefriday #microscopy 🧪🔬
Reposted by Estefania Sanchez-Vasquez
The law of the jungle.
Interactions of cells in a collective lead to global rotation.
In 80% of the case HUVEC cells turn clockwise.
How many cells does it take for this to happen?
Interactions of cells in a collective lead to global rotation.
In 80% of the case HUVEC cells turn clockwise.
How many cells does it take for this to happen?
November 21, 2025 at 1:07 PM
The law of the jungle.
Interactions of cells in a collective lead to global rotation.
In 80% of the case HUVEC cells turn clockwise.
How many cells does it take for this to happen?
Interactions of cells in a collective lead to global rotation.
In 80% of the case HUVEC cells turn clockwise.
How many cells does it take for this to happen?
Reposted by Estefania Sanchez-Vasquez
Honored to hear this—helping researchers cut through the noise is why we build Paperpile. Thanks for the shout-out! 🙌
Want to shout out @paperpile.com for being one of the best tools out there for academics!
The endless inflow of GREAT academic research can feel so daunting to me in busy mid-career. But paperpile lets me tag, organize, and annotate new research straight from links. Sooo satisfying 🧘♂️
The endless inflow of GREAT academic research can feel so daunting to me in busy mid-career. But paperpile lets me tag, organize, and annotate new research straight from links. Sooo satisfying 🧘♂️
November 21, 2025 at 3:16 PM
Honored to hear this—helping researchers cut through the noise is why we build Paperpile. Thanks for the shout-out! 🙌
Reposted by Estefania Sanchez-Vasquez
Highly recommended and should be read by all (future) group leaders! Thanks for sharing your personal struggles also
@jenheemstra.bsky.social 🧪
@jenheemstra.bsky.social 🧪
November 18, 2025 at 8:18 PM
Highly recommended and should be read by all (future) group leaders! Thanks for sharing your personal struggles also
@jenheemstra.bsky.social 🧪
@jenheemstra.bsky.social 🧪
Reposted by Estefania Sanchez-Vasquez
The lab’s first pre-print! We investigated how growth-inducing Erk activity waves are regulated in regenerating zebrafish scales. We discovered that Erk waves are followed by waves of expression of their own inhibitors, as predicted by excitable waves theory. tinyurl.com/26r2cmpj
November 20, 2025 at 6:11 PM
The lab’s first pre-print! We investigated how growth-inducing Erk activity waves are regulated in regenerating zebrafish scales. We discovered that Erk waves are followed by waves of expression of their own inhibitors, as predicted by excitable waves theory. tinyurl.com/26r2cmpj
Reposted by Estefania Sanchez-Vasquez
@uofcalifornia.bsky.social System Reverses Decision to End Incentives for Postdoc Program Hires https://bit.ly/49ZWrVa
#EDUSky #HigherEd #AcademicSky
#EDUSky #HigherEd #AcademicSky
November 20, 2025 at 10:31 PM
@uofcalifornia.bsky.social System Reverses Decision to End Incentives for Postdoc Program Hires https://bit.ly/49ZWrVa
#EDUSky #HigherEd #AcademicSky
#EDUSky #HigherEd #AcademicSky
Reposted by Estefania Sanchez-Vasquez
Come be our colleague! We are looking for a tenure track cell / molecular biologist with focus on biochemical sciences. Strong bio department, lovely rural communities and living among the redwoods! Ask me questions !
careers.humboldt.edu/mob/hm/en-us...
careers.humboldt.edu/mob/hm/en-us...
Tenure Track Faculty - Department of Biological Sciences (Cellular and Molecular Biology)
Cal Poly Humboldt and the Department of Biological Sciences invites applicants for a full-time, academic year, tenure-track faculty position with an emphasis in Cellular and Molecular Biology with a f...
careers.humboldt.edu
November 21, 2025 at 12:29 AM
Come be our colleague! We are looking for a tenure track cell / molecular biologist with focus on biochemical sciences. Strong bio department, lovely rural communities and living among the redwoods! Ask me questions !
careers.humboldt.edu/mob/hm/en-us...
careers.humboldt.edu/mob/hm/en-us...
Reposted by Estefania Sanchez-Vasquez
Come discuss recent breakthroughs in RNA biology, from molecules to organisms, at the EMBO | EMBL Symposium 'The complex life of RNA'! 👉 s.embl.org/ees26-12-bl
Submit your abstract by 7 July and present your research at #EESRNA 🥼
Submit your abstract by 7 July and present your research at #EESRNA 🥼
November 14, 2025 at 4:33 PM
Come discuss recent breakthroughs in RNA biology, from molecules to organisms, at the EMBO | EMBL Symposium 'The complex life of RNA'! 👉 s.embl.org/ees26-12-bl
Submit your abstract by 7 July and present your research at #EESRNA 🥼
Submit your abstract by 7 July and present your research at #EESRNA 🥼
Reposted by Estefania Sanchez-Vasquez
UC Santa Cruz was ranked the #1 public research university in the world for highly cited researchers over the past 10 years (2014-2024) by Clarivate.
UC Santa Cruz is the top public research university in the world for highly cited researchers amid strong 2025 list
25 UC Santa Cruz researchers earned a spot on the prestigious annual list.
news.ucsc.edu
November 20, 2025 at 5:40 PM
UC Santa Cruz was ranked the #1 public research university in the world for highly cited researchers over the past 10 years (2014-2024) by Clarivate.
Reposted by Estefania Sanchez-Vasquez
We just released a new major version of TrackMate (v8), the cell and organelle tracking plugin of Fiji.
It ships many new features, detailed below, but that are articulated around the following:
It ships many new features, detailed below, but that are articulated around the following:
November 20, 2025 at 11:42 AM
We just released a new major version of TrackMate (v8), the cell and organelle tracking plugin of Fiji.
It ships many new features, detailed below, but that are articulated around the following:
It ships many new features, detailed below, but that are articulated around the following:
Reposted by Estefania Sanchez-Vasquez
Please take a look to this fantastic thread of
@luisherhuertas.bsky.social
leading this work from our lab that pioneers the use of CRISPR-RfxCas13d screenings to uncover new maternal regulators of early development in fish. More exciting screenings are coming with new factors, stay tuned! :)
@luisherhuertas.bsky.social
leading this work from our lab that pioneers the use of CRISPR-RfxCas13d screenings to uncover new maternal regulators of early development in fish. More exciting screenings are coming with new factors, stay tuned! :)
✨ Happy to share that our work is now published in @embojournal.org ! ✨
Our fantastic collaboration between @crisprscan.bsky.social
@bazzinilab.bsky.social
Here is the updated thread (1/13):
www.embopress.org/doi/full/10....
Our fantastic collaboration between @crisprscan.bsky.social
@bazzinilab.bsky.social
Here is the updated thread (1/13):
www.embopress.org/doi/full/10....
CRISPR-RfxCas13d screening uncovers Bckdk as a post-translational regulator of maternal-to-zygotic transition in teleosts | The EMBO Journal
imageimagePost-translational regulation during the maternal-to-zygotic transition (MZT) remains
largely unexplored. Using an optimized CRISPR-RfxCas13d screening strategy, this study
identifies Bckdk ...
www.embopress.org
November 20, 2025 at 4:11 PM
Please take a look to this fantastic thread of
@luisherhuertas.bsky.social
leading this work from our lab that pioneers the use of CRISPR-RfxCas13d screenings to uncover new maternal regulators of early development in fish. More exciting screenings are coming with new factors, stay tuned! :)
@luisherhuertas.bsky.social
leading this work from our lab that pioneers the use of CRISPR-RfxCas13d screenings to uncover new maternal regulators of early development in fish. More exciting screenings are coming with new factors, stay tuned! :)
Reposted by Estefania Sanchez-Vasquez
Dear #Neuroscience researchers, I am Guest Editing an issue in @devdynamics.bsky.social on NEURAL MIGRATION.
Due date: March 31, 2026.
Great opportunity to showcase your findings on neural migration. #DevBio
Please reskeet 🙏
anatomypubs.onlinelibrary.wiley.com/journal/1097...
Due date: March 31, 2026.
Great opportunity to showcase your findings on neural migration. #DevBio
Please reskeet 🙏
anatomypubs.onlinelibrary.wiley.com/journal/1097...
Developmental Dynamics
<em>Developmental Dynamics</em> is a developmental biology journal publishing novel discoveries that advance our understanding in development, morphology, evolution, and disease.
anatomypubs.onlinelibrary.wiley.com
November 20, 2025 at 4:40 PM
Dear #Neuroscience researchers, I am Guest Editing an issue in @devdynamics.bsky.social on NEURAL MIGRATION.
Due date: March 31, 2026.
Great opportunity to showcase your findings on neural migration. #DevBio
Please reskeet 🙏
anatomypubs.onlinelibrary.wiley.com/journal/1097...
Due date: March 31, 2026.
Great opportunity to showcase your findings on neural migration. #DevBio
Please reskeet 🙏
anatomypubs.onlinelibrary.wiley.com/journal/1097...
Reposted by Estefania Sanchez-Vasquez
This week we introduced an #assembloid-based platform to begin studying how #enteroviruses affect human neuromuscular systems.
This is a collaboration with Jan Carette here at Stanford.
Work led by Christine Peters, Jimena Andersen and Min-Yin Li.
This is a collaboration with Jan Carette here at Stanford.
Work led by Christine Peters, Jimena Andersen and Min-Yin Li.
November 20, 2025 at 4:44 PM
This week we introduced an #assembloid-based platform to begin studying how #enteroviruses affect human neuromuscular systems.
This is a collaboration with Jan Carette here at Stanford.
Work led by Christine Peters, Jimena Andersen and Min-Yin Li.
This is a collaboration with Jan Carette here at Stanford.
Work led by Christine Peters, Jimena Andersen and Min-Yin Li.
Reposted by Estefania Sanchez-Vasquez
Single-nucleotide resolution mapping of m6A of zebrafish mRNAs in early embryonic development links m6A modifications to the maternal-to-zygotic transition https://www.biorxiv.org/content/10.1101/2025.11.19.688951v1
November 19, 2025 at 4:33 PM
Single-nucleotide resolution mapping of m6A of zebrafish mRNAs in early embryonic development links m6A modifications to the maternal-to-zygotic transition https://www.biorxiv.org/content/10.1101/2025.11.19.688951v1
Reposted by Estefania Sanchez-Vasquez
Tomoya Hotani, Yuki Ohsaki, Wataru Sakai & team discover that FANCD2 responds to both DNA damage & oleic acid exposure, providing insights into the pathogenesis of lipid dysregulation in Fanconi anemia.
Highlight: journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
Highlight: journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
November 19, 2025 at 10:02 AM
Tomoya Hotani, Yuki Ohsaki, Wataru Sakai & team discover that FANCD2 responds to both DNA damage & oleic acid exposure, providing insights into the pathogenesis of lipid dysregulation in Fanconi anemia.
Highlight: journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
Highlight: journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
Reposted by Estefania Sanchez-Vasquez
SAVE THE DATE! Stoked to organize the 2026 Santa Cruz Developmental Biology Meeting with @rashmi-priya.bsky.social, @lowelab.bsky.social, and Shelbi Russell. Come learn about Biomedicine, Biomechanics, and the Biosphere, August 24-28, 2026. Registration dates, etc., coming soon! Please RT
November 19, 2025 at 8:23 PM
SAVE THE DATE! Stoked to organize the 2026 Santa Cruz Developmental Biology Meeting with @rashmi-priya.bsky.social, @lowelab.bsky.social, and Shelbi Russell. Come learn about Biomedicine, Biomechanics, and the Biosphere, August 24-28, 2026. Registration dates, etc., coming soon! Please RT
Reposted by Estefania Sanchez-Vasquez
Wisconsin Evolution is accepting applications for our Seminar Series' Early Career Scientist Award. Come share your evolution research and visit UW-Madison's evolution community. Open to grad students and postdocs (<5 yrs post PhD) from outside UW-Madison.
Apply by Dec 15th here: shorturl.at/4a4O6
Apply by Dec 15th here: shorturl.at/4a4O6
Early Career Scientist Awards 2026
Application to the UW-Madison Evolution Seminar Series - Early Career Scientist Awards.
urldefense.com
November 19, 2025 at 8:55 PM
Wisconsin Evolution is accepting applications for our Seminar Series' Early Career Scientist Award. Come share your evolution research and visit UW-Madison's evolution community. Open to grad students and postdocs (<5 yrs post PhD) from outside UW-Madison.
Apply by Dec 15th here: shorturl.at/4a4O6
Apply by Dec 15th here: shorturl.at/4a4O6