Cells & Development
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cellsdev.bsky.social
Cells & Development
@cellsdev.bsky.social
'Cells & Development' journal (formerly 'Mechanisms of Development'). Official journal of the International Society of Developmental Biology isdb.bsky.social
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From January 2021 MoD will become “CELLS & DEVELOPMENT”, subtitle: “CELL AND DEVELOPMENTAL BIOLOGY AND THEIR QUANTITATIVE APPROCHES”. We expect that C&D will become a forum for interdisciplinary research combining biology, physics and mathematics to study cell and dev biology.
Reposted by Cells & Development
Sir John Gurdon was also the president of the @isdb.bsky.social from 1989-1992. He also facilitated or influenced the establishment of the @bsdb.bsky.social, @lasdb.bsky.social, many institutes, and generations of scientists, and worked with @biologists.bsky.social for decades. You will be missed.
"His secret weapons were an unquenchable curiosity and continuing hands-on experimentation at the bench with his beautiful frog embryos and oocytes".

A thoughtful tribute to the life of Sir John Gurdon by Edward M. De Robertis that we really recommend everyone to read.
doi.org/10.1016/j.cd...
November 7, 2025 at 9:23 PM
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"His secret weapons were an unquenchable curiosity and continuing hands-on experimentation at the bench with his beautiful frog embryos and oocytes".

A thoughtful tribute to the life of Sir John Gurdon by Edward M. De Robertis that we really recommend everyone to read.
doi.org/10.1016/j.cd...
November 7, 2025 at 9:12 PM
"His secret weapons were an unquenchable curiosity and continuing hands-on experimentation at the bench with his beautiful frog embryos and oocytes".

A thoughtful tribute to the life of Sir John Gurdon by Edward M. De Robertis that we really recommend everyone to read.
doi.org/10.1016/j.cd...
November 7, 2025 at 9:12 PM
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We love frogs too 🐸!
🐸 Xenopus laevis 💚 The frog that shaped modern developmental biology! ✨ Xenopus embryos have revealed how the body axis forms, cells choose their fate, and tissues self-organize during early development 📹 Video by Bioquest Sudio and Xenbase #ModelMonday #DevBio
November 3, 2025 at 10:12 PM
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🐸 Xenopus laevis 💚 The frog that shaped modern developmental biology! ✨ Xenopus embryos have revealed how the body axis forms, cells choose their fate, and tissues self-organize during early development 📹 Video by Bioquest Sudio and Xenbase #ModelMonday #DevBio
November 3, 2025 at 8:01 PM
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From the lab of Maxwell Heiman discussing the interesting topic of apical ECM and the function of sensing organs and how these ECM proteins can both mechanically and biochemically modulate the organ's functions.
doi.org/10.1016/j.cd...
October 30, 2025 at 5:48 PM
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From the lab of Brian Stramer discussing how the ECM actively involved in shaping embryo morphogenesis.
doi.org/10.1016/j.cd...
October 30, 2025 at 5:48 PM
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From the lab of Kenneth Yamada showing how mRNAs coding for basement membrane proteins are polarised apically in mouse embryonic salivary gland outer epithelial cells and are trafficked by microtubules.
doi.org/10.1016/j.cd...
October 30, 2025 at 5:48 PM
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In the spirit 👻 of Freaky Friday 🎃, here is a beautiful yet eery video of zebrafish retina development showing horizontal cells (🔵) finding their way out of the crowded amacrine (🟠) layer to settle beneath the photoreceptors. Happy #Halloween!
🎥: PhD student Rae Wong from the @nordenlab.bsky.social
October 31, 2025 at 2:29 PM
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The first original research paper from my lab is now out in @biorxivpreprint.bsky.social! www.biorxiv.org/content/10.1...
Tracheal development is an amazing model to study morphogenesis. There are great works out there that show how this tissue elongates, interconnects, and forms branches (1/n)
Adhesion to a common ECM mediates interdependence in tissue morphogenesis in Drosophila
For organs to be functional, the cells and tissues that constitute them must effectively interact with each other and coordinate their behaviours. Halfway during Drosophila embryogenesis, two lateral ...
www.biorxiv.org
March 17, 2025 at 5:21 PM
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The ECM is no longer in the back seat when it comes to development. Check out our special issue "Dynamics of the extracellular matrix in development, cell physiology and disease" with 8 selected articles to learn more: A 🧵 www.sciencedirect.com/special-issu...
Cells & Development | Dynamics of the extracellular matrix in development, cell physiology and disease. | ScienceDirect.com by Elsevier
Extracellular matrices (ECMs) are everywhere in our body– from the sheet-like basement membranes that line epithelia and other tissues - to the loose stromal arrays of mesenchyme - to the rigid struct...
www.sciencedirect.com
October 30, 2025 at 5:48 PM
Reposted by Cells & Development
Special issue looking at the relationship between ECM and development. The role of ECM in shaping developmental dynamics is increasingly recognised. Check it out:
October 30, 2025 at 5:49 PM
The ECM is no longer in the back seat when it comes to development. Check out our special issue "Dynamics of the extracellular matrix in development, cell physiology and disease" with 8 selected articles to learn more: A 🧵 www.sciencedirect.com/special-issu...
Cells & Development | Dynamics of the extracellular matrix in development, cell physiology and disease. | ScienceDirect.com by Elsevier
Extracellular matrices (ECMs) are everywhere in our body– from the sheet-like basement membranes that line epithelia and other tissues - to the loose stromal arrays of mesenchyme - to the rigid struct...
www.sciencedirect.com
October 30, 2025 at 5:48 PM
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How do endodermal cells behave during gastrulation? In this paper, the authors found that a gradient of BMP regulates mesoderm and endoderm convergent extension. Endoderm cells also use the mesoderm and Cxcr4a signalling to guide their movement. The imaging is beautiful!
doi.org/10.1016/j.cd...
October 17, 2025 at 6:27 PM
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Cell-cell junction proteins like ZO-1 not only play a critical role in the mechanical interaction between cells, but also participate in the biochemical signalling to coordinate the cell sheet. Check out this review on collective cell migration here to learn more: doi.org/10.1016/j.cd...
October 24, 2025 at 11:32 PM
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ZO-1,cell-cell and cell-matrix interactions...
Cell-cell junction proteins like ZO-1 not only play a critical role in the mechanical interaction between cells, but also participate in the biochemical signalling to coordinate the cell sheet. Check out this review on collective cell migration here to learn more: doi.org/10.1016/j.cd...
October 25, 2025 at 4:54 PM
Cell-cell junction proteins like ZO-1 not only play a critical role in the mechanical interaction between cells, but also participate in the biochemical signalling to coordinate the cell sheet. Check out this review on collective cell migration here to learn more: doi.org/10.1016/j.cd...
October 24, 2025 at 11:32 PM
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The October 10 #SDBPostdocSeminar with @austinseroka1.bsky.social of Fred Hutchinson Cancer Center and @dingwallaby.bsky.social‬ of @upenn.edu has been posted. Thank you to moderators @sarahcolijn.bsky.social and @shyama13.bsky.social. Watch here: youtu.be/k4OJHnZV2gk
SDB Ethel Browne Harvey Postdoctoral Seminar Series - Austin Seroka and Heather Dingwall
YouTube video by Society for Developmental Biology
youtu.be
October 17, 2025 at 7:56 PM
How do endodermal cells behave during gastrulation? In this paper, the authors found that a gradient of BMP regulates mesoderm and endoderm convergent extension. Endoderm cells also use the mesoderm and Cxcr4a signalling to guide their movement. The imaging is beautiful!
doi.org/10.1016/j.cd...
October 17, 2025 at 6:27 PM
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A new review from the @mayorlab.bsky.social on the chemical and physical cues regulating neural crest cells migration is out. Check it out!
www.annualreviews.org/content/jour...
Neural Crest Migration Orchestrated by Molecular and Mechanical Signals
The neural crest is a highly migratory multipotent cell population traveling large distances in the vertebrate embryo. Neural crest cells migrate collectively in subpopulations, ranging in size from s...
www.annualreviews.org
October 13, 2025 at 8:15 PM
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In honor of the passing of Sir John Gurdon, we will revisit the concept of chimerism across scales in this review from the lab of @drmichaellevin.bsky.social. Grafting and nucleus transplanting have been the cornerstone of modern #devbio. We have come so far!
www.sciencedirect.com/science/arti...
October 11, 2025 at 12:14 PM
In honor of the passing of Sir John Gurdon, we will revisit the concept of chimerism across scales in this review from the lab of @drmichaellevin.bsky.social. Grafting and nucleus transplanting have been the cornerstone of modern #devbio. We have come so far!
www.sciencedirect.com/science/arti...
October 11, 2025 at 12:14 PM
Reposted by Cells & Development
We often talk about what signals does the organiser release. But have you ever stopped and asked what does it mean to be the organiser? What cells make up the organiser? Where do they go? What do they do?
Well this review by Claudio Stern may give you the answers:
doi.org/10.1016/j.cd...
October 3, 2025 at 4:36 PM
We often talk about what signals does the organiser release. But have you ever stopped and asked what does it mean to be the organiser? What cells make up the organiser? Where do they go? What do they do?
Well this review by Claudio Stern may give you the answers:
doi.org/10.1016/j.cd...
October 3, 2025 at 4:36 PM
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In this intriguing paper published from the lab of @amartinezarias.bsky.social , they looked at the effects of size on morphology, tissue composition, and gene expression of gastruloid development. They found that AP elongation dynamics is size-dependent! Check it out here:
doi.org/10.1016/j.cd...
September 26, 2025 at 5:17 PM