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cellsdev.bsky.social
Cells & Development
@cellsdev.bsky.social
1.2K followers 480 following 55 posts
'Cells & Development' journal (formerly 'Mechanisms of Development'). Official journal of the International Society of Developmental Biology isdb.bsky.social
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cellsdev.bsky.social
Cells & Development @cellsdev.bsky.social · Nov 15
From January 2021 MoD will become “CELLS & DEVELOPMENT”, subtitle: “CELL AND DEVELOPMENTAL BIOLOGY AND THEIR QUANTITATIVE APPROCHES”. We expect that C&D will become a forum for interdisciplinary research combining biology, physics and mathematics to study cell and dev biology.
cellsdev.bsky.social
An amazing course!
You'll learn: genetic manipulation including CRISPR-Cas9, oragnoid generation, explant systems, biomechanics, high-resolution imaging and analysis, bioinformatics, and more!

Register now!
Deadline: January 16, 2026
January 4, 2026 at 10:30 PM
Reposted by Cells & Development
isdb.bsky.social
Modern Xenopus research uses this system to study #devbio, genetic diseases, biomechanics, and cell biology. If you want hands-on experience, register now to the CSHL Cell & Developmental Biology of Xenopus:
Gene Discovery & Disease
meetings.cshl.edu/courses.aspx...
Deadline: January 16, 2026
Cell & Developmental Biology of Xenopus: Gene Discovery & Disease
Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.
meetings.cshl.edu
January 4, 2026 at 10:28 PM
Reposted by Cells & Development
cellsdev.bsky.social
Thank you for all the engagements. Have a wonderful holiday. We will see you again next year 👋
isdb.bsky.social International Society of Developmental Biology @isdb.bsky.social · 16d
This is our last post of the year. Hope you have a wonderful holidays. Remember, good science only comes from a well-rested mind. We will see you again next year! #MicroscopyMonday #Christmas
Image: 3D Christmas spheroids
Staining: Phalloidin
Photo credit: Postdoc Hoang Anh Le, @ucl-cdb.bsky.social
December 22, 2025 at 11:44 AM
cellsdev.bsky.social
Thank you for all the engagements. Have a wonderful holiday. We will see you again next year 👋
isdb.bsky.social International Society of Developmental Biology @isdb.bsky.social · 16d
This is our last post of the year. Hope you have a wonderful holidays. Remember, good science only comes from a well-rested mind. We will see you again next year! #MicroscopyMonday #Christmas
Image: 3D Christmas spheroids
Staining: Phalloidin
Photo credit: Postdoc Hoang Anh Le, @ucl-cdb.bsky.social
December 22, 2025 at 11:44 AM
Reposted by Cells & Development
isdb.bsky.social
This is our last post of the year. Hope you have a wonderful holidays. Remember, good science only comes from a well-rested mind. We will see you again next year! #MicroscopyMonday #Christmas
Image: 3D Christmas spheroids
Staining: Phalloidin
Photo credit: Postdoc Hoang Anh Le, @ucl-cdb.bsky.social
December 22, 2025 at 11:39 AM
Reposted by Cells & Development
opazo.bsky.social
✨ Blinking #nanobodies that work for single-molecule localization 🔬
Our new preprint shows that the self-blinking dye JF635b restores robust, buffer-free blinking in #nanobodies, enabling reliable #dSTORM, #MINFLUX, and more, without chemical-switching buffers. Opening new possibilities for #ExM!
December 22, 2025 at 10:45 AM
Reposted by Cells & Development
cellsdev.bsky.social
Tissue-resident macrophages are doing more than just protecting from infection. In this interesting paper, René Fernando Abarca-Buis et al shows that they can promote reepithelialization and blastema formation and regulate the maturation of chondrocytes. Check it out here:
doi.org/10.1016/j.cd...
Fig. 1. Doble immunodetection of CD68 and F4/80 during ear hole regeneration in early postnatal mice. Fig. 6. Clodronate liposomes treated ears in re-differentiation show acceleration of cartilage maturation. Fig. 4. Modifications in the regenerative response by the treatment with clodronate liposomes during wound healing phase of early postnatal mice ear hole regeneration.
November 28, 2025 at 5:57 PM
Reposted by Cells & Development
cellsdev.bsky.social
Check out the summary written by our Editor in Chief, Professor Roberto Mayor:
www.sciencedirect.com/science/arti...

And if you missed it, here is the link to Part I of the collection:
www.sciencedirect.com/special-issu...
December 17, 2025 at 3:45 PM
Reposted by Cells & Development
cellsdev.bsky.social
We're in love with this cover image! 🧡
Part II of our Special Collection celebrating the Centennial of the Discovery of The Organiser is here. This issue focuses on the work presented at the Centennial Symposium at the University of Freiburg in September 2024:
www.sciencedirect.com/journal/cell...
Many small photos taken from the symposium organised to reveal Spemann and Mangold in the background.
December 17, 2025 at 3:45 PM
Reposted by Cells & Development
isdb.bsky.social
Check out Part II of our special collection celebrating the centennial of the discovery of the organiser. From classical developmental biology, to tissue mechanics, and organoid and plant development, we've got it all!
cellsdev.bsky.social Cells & Development @cellsdev.bsky.social · 21d
We're in love with this cover image! 🧡
Part II of our Special Collection celebrating the Centennial of the Discovery of The Organiser is here. This issue focuses on the work presented at the Centennial Symposium at the University of Freiburg in September 2024:
www.sciencedirect.com/journal/cell...
Many small photos taken from the symposium organised to reveal Spemann and Mangold in the background.
December 17, 2025 at 3:48 PM
Reposted by Cells & Development
isdb.bsky.social
❗PREPRINT ALERT❗
doi.org/10.64898/202...
The lab of M. Lisa Manning at @syracuseu.bsky.social in collaboration with Ale Mongera at @ucl-cdb.bsky.social show that in the avian presomitic mesoderm, Contact Inhibition of Locomotion has a tissue-wide effect, making tissue act like a fluid under tension.
December 17, 2025 at 5:20 PM
cellsdev.bsky.social
We're in love with this cover image! 🧡
Part II of our Special Collection celebrating the Centennial of the Discovery of The Organiser is here. This issue focuses on the work presented at the Centennial Symposium at the University of Freiburg in September 2024:
www.sciencedirect.com/journal/cell...
Many small photos taken from the symposium organised to reveal Spemann and Mangold in the background.
December 17, 2025 at 3:45 PM
Reposted by Cells & Development
socdevbio.bsky.social
The next the Ethel Browne Harvey Postdoc Seminar will be (today) Friday, December 12 at 3 pm Eastern Time with Weiyi Qian @weiyiqian.bsky.social at NYU Grossman School of Medicine and Robyn Allen @universityofky.bsky.social. Register today and join us. bit.ly/46rb0NZ #SDBPostdocSeminar
Society for Developmental Biology Ethel Browne Harvey Postdoctoral Seminar Series Friday, December 12, 2025, 3:00pm - 4:00 pm Eastern Time Weiyi Qian (New York University Grossman School of Medicine) Tug of war — Tissue splitting driven by cell-cell and cell-matrix adhesions Robyn Allen (University of Kentucky) Fibroblasts from highly regenerative mammals resist mechanical cues to drive regeneration
December 12, 2025 at 3:21 PM
Reposted by Cells & Development
cellsdev.bsky.social
Vertebrates can use entirely different mechanisms to generate its anterior and posterior dorsal tissue. In this thorough review from the lab of Lance Davidson, different morphogenetic events are compared between the front and the back in a developing embryo. Check it out:
doi.org/10.1016/j.cd...
Fig. 1. Comparative stages of transition from primary-to-posterior dorsal axial tissue formation. A dorsal and sagittal comparison of simplified CNS morphology in at the stage(s) of PNP closure (presumed junctional neurulation) between model organisms commonly used to study neurulation processes. A dorsal view of the shared structural characteristics between vertebrates at the posterior end depicts the anterior portion of the posterior processes which have completed neural tube closure and are in the process of segmenting somites from pre-formed PSM. Dashes mark the regions where primary and secondary neurulation processes occur at the same time and are overlapping (transition zone). Posterior to established neural tube and PSM is the region containing the NMP cell population, which are proliferating and maturing to form PSM and neural tube structures in an anterior to posterior direction. Mammals have formed roughly between 28 and 30 somites at neuropore closure (E9.5–10 in mouse, day 27 in humans). Avian have formed 22 somites at HH13, whereas amphibians have formed only 6–7 somites by NF 20. Finally, zebrafish have 21 somites at 19.5 hpf, which corresponds to the stage of neural primordium elongation, without convergence. Fig. 2. Antero-posterior progression of neurulation and somitogenesis. A graphical representation of primary and posterior processes that generate identical, uninterrupted structures through a transition zone. All vertebrates begin primary processes with a predetermined superficial neural cell layer, that converges at the midline to form a single lumen and pre-somitic mesoderm that condenses and segregates into somites. Posterior processes are established from a multi-potent NMP cell population that diverge to form separate neural and mesodermal populations and eventually forms structures indistinguishable from primary structures. These processes are hypothesized to occur at the same time within the transition zone, where primary processes progressively transition into posterior processes. Fig. 3. A comparison of naïve/pluripotent/stem cell populations and organizer regions. An organizer is capable of modulating the cell identities of neighboring cell populations through expression of various BMP antagonists and additional growth factors. Naïve cells are undifferentiated cells that are capable of developing into various cell types, dependent on the externally applied conditions. The diagrams are representative of the transplantation experiments completed by Spemann and Mangold, which illustrates the organizer's ability to induce neural identity from host cells.
December 12, 2025 at 2:00 PM
cellsdev.bsky.social
One of our favourite activities each year too.
jcb.org Journal of Cell Biology @jcb.org · 26d
Help choose JCB’s cover of the year! Explore 12 breathtaking images submitted by our talented authors and vote for your favorite. Don’t miss your chance to have your say in celebrating the beauty of science. Voting closes on December 31! 👉 www.surveymonkey.com/r/JCB2025Cov...

#ScienceArt
December 12, 2025 at 2:18 PM
Reposted by Cells & Development
jcb.org
Help choose JCB’s cover of the year! Explore 12 breathtaking images submitted by our talented authors and vote for your favorite. Don’t miss your chance to have your say in celebrating the beauty of science. Voting closes on December 31! 👉 www.surveymonkey.com/r/JCB2025Cov...

#ScienceArt
December 12, 2025 at 2:15 PM
Reposted by Cells & Development
isdb.bsky.social
Looks like a really useful tool!
haoyin.bsky.social Hao Yin @haoyin.bsky.social · 26d
#SpatialTranscriptomics

STcompare
github.com/JEFworks-Lab...

Test your gene of interest if it is differentially spatially patterned (r, p, s)🤠
Spatial correlation
Spatial fold change
Control for spatial autocorrelation

@jef.works bioRxiv 2025
www.biorxiv.org/content/10.1...
December 12, 2025 at 2:13 PM
cellsdev.bsky.social
Vertebrates can use entirely different mechanisms to generate its anterior and posterior dorsal tissue. In this thorough review from the lab of Lance Davidson, different morphogenetic events are compared between the front and the back in a developing embryo. Check it out:
doi.org/10.1016/j.cd...
Fig. 1. Comparative stages of transition from primary-to-posterior dorsal axial tissue formation. A dorsal and sagittal comparison of simplified CNS morphology in at the stage(s) of PNP closure (presumed junctional neurulation) between model organisms commonly used to study neurulation processes. A dorsal view of the shared structural characteristics between vertebrates at the posterior end depicts the anterior portion of the posterior processes which have completed neural tube closure and are in the process of segmenting somites from pre-formed PSM. Dashes mark the regions where primary and secondary neurulation processes occur at the same time and are overlapping (transition zone). Posterior to established neural tube and PSM is the region containing the NMP cell population, which are proliferating and maturing to form PSM and neural tube structures in an anterior to posterior direction. Mammals have formed roughly between 28 and 30 somites at neuropore closure (E9.5–10 in mouse, day 27 in humans). Avian have formed 22 somites at HH13, whereas amphibians have formed only 6–7 somites by NF 20. Finally, zebrafish have 21 somites at 19.5 hpf, which corresponds to the stage of neural primordium elongation, without convergence. Fig. 2. Antero-posterior progression of neurulation and somitogenesis. A graphical representation of primary and posterior processes that generate identical, uninterrupted structures through a transition zone. All vertebrates begin primary processes with a predetermined superficial neural cell layer, that converges at the midline to form a single lumen and pre-somitic mesoderm that condenses and segregates into somites. Posterior processes are established from a multi-potent NMP cell population that diverge to form separate neural and mesodermal populations and eventually forms structures indistinguishable from primary structures. These processes are hypothesized to occur at the same time within the transition zone, where primary processes progressively transition into posterior processes. Fig. 3. A comparison of naïve/pluripotent/stem cell populations and organizer regions. An organizer is capable of modulating the cell identities of neighboring cell populations through expression of various BMP antagonists and additional growth factors. Naïve cells are undifferentiated cells that are capable of developing into various cell types, dependent on the externally applied conditions. The diagrams are representative of the transplantation experiments completed by Spemann and Mangold, which illustrates the organizer's ability to induce neural identity from host cells.
December 12, 2025 at 2:00 PM
Reposted by Cells & Development
zimengwu33.bsky.social
Pleased to say that Jonas Hartmann (bs-less) and I have finally released DySTrack (“diss track”) - Dynamic Sample Tracking.

It’s a Python-based, modular tool that brings smart microscopy to everyday imaging on commercial systems.

Preprint: www.biorxiv.org/content/10.6...

[1/6]
December 8, 2025 at 9:48 AM
Reposted by Cells & Development
zebrafishrock.bsky.social
Very useful tool, for those interested! 🧪
zimengwu33.bsky.social Zimeng Wu @zimengwu33.bsky.social · Dec 8
Pleased to say that Jonas Hartmann (bs-less) and I have finally released DySTrack (“diss track”) - Dynamic Sample Tracking.

It’s a Python-based, modular tool that brings smart microscopy to everyday imaging on commercial systems.

Preprint: www.biorxiv.org/content/10.6...

[1/6]
December 8, 2025 at 9:49 AM
Reposted by Cells & Development
isdb.bsky.social
You can also find the Github code here:
github.com/WhoIsJack/Dy...
GitHub - WhoIsJack/DySTrack: A simple automated feedback microscopy tool for live tracking of moving samples.
A simple automated feedback microscopy tool for live tracking of moving samples. - WhoIsJack/DySTrack
github.com
December 8, 2025 at 9:31 PM
Reposted by Cells & Development
isdb.bsky.social
Do your samples move out of view? Tired of manually adjusting the stage? Introducing DySTrack developed by @zimengwu33.bsky.social and Jonas Hartmann from UCL, a tool that can be integrated into modern microscopes to automate the tracking of moving samples. #MicroscopyMonday doi.org/10.64898/202...
December 8, 2025 at 9:31 PM
Reposted by Cells & Development
cellsdev.bsky.social
Call for papers: Chilean Developmental Biology: at Home and Around the World - Cells & Development.
If you're a Chile-based scientist and Chilean researcher working abroad, please consider submit to us for this special issue.
‼️Submission deadline: 30 June 2026
www.sciencedirect.com/special-issu...
November 14, 2025 at 5:31 PM
Reposted by Cells & Development
socdevbio.bsky.social
📣 Applications Open!
SDB is seeking applicants for the 2026 GetHIRED! Internship, a unique chance to gain hands-on experience supporting an e-course for postdocs entering the academic job market.
📆 Deadline: December 15, 2025.
Learn more & apply today: www.sdbonline.org/gethired_int...
December 5, 2025 at 3:09 PM
Reposted by Cells & Development
cellsdev.bsky.social
Principles in mechanical engineering can be applied to study biomaterials, such as the notochord. In this theoretical study, Curcio et al investigated how the different ways of notochord stacking affects its structural rigidity. A staircase stacking seems to be better!
doi.org/10.1016/j.cd...
Fig. 1. Initial geometries and boundary conditions for pressurization and three-point bending studies. Fig. 4. Examples of three-point bending. Lateral and/or transverse displacements are nondimensionalized, dividing by initial cell dimension d(init). Fig. 2. Inflation study: geometric changes. Fig. 3. Pressure study: resulting tensions.
December 6, 2025 at 2:51 PM