Felipe Opazo
@opazo.bsky.social
PI at the Uni Medical Center Göttingen (UMG), Founder and CTO of NanoTag Biotechnologies. Using nanobodies for super-resolution microscopy in neurosciences. Opinions are my own.
Happy to tell that I got my tenured professorship at the University Medical Center in Göttingen 🇩🇪!
Grateful for my students, mentors, international collaborators, the @nanotag.bsky.social team, and my family (dog included 🐾). Motivated to keep pushing science, innovation, startups, and education 🌍✨
Grateful for my students, mentors, international collaborators, the @nanotag.bsky.social team, and my family (dog included 🐾). Motivated to keep pushing science, innovation, startups, and education 🌍✨
October 17, 2025 at 3:06 PM
Happy to tell that I got my tenured professorship at the University Medical Center in Göttingen 🇩🇪!
Grateful for my students, mentors, international collaborators, the @nanotag.bsky.social team, and my family (dog included 🐾). Motivated to keep pushing science, innovation, startups, and education 🌍✨
Grateful for my students, mentors, international collaborators, the @nanotag.bsky.social team, and my family (dog included 🐾). Motivated to keep pushing science, innovation, startups, and education 🌍✨
Reposted by Felipe Opazo
#NanoTag joins the Life Science Ecosystem at Nordic Life Science Days #NLSDays2025 in Gothenburg!🇸🇪 Meet our CEO Hansjörg Götzke at the Booth B03:46 (German Pavilion), and discover our sdAb platforms🦙, protein production services, and research tools🔬advancing #LifeScience & #Biomedicine.
October 7, 2025 at 8:17 AM
#NanoTag joins the Life Science Ecosystem at Nordic Life Science Days #NLSDays2025 in Gothenburg!🇸🇪 Meet our CEO Hansjörg Götzke at the Booth B03:46 (German Pavilion), and discover our sdAb platforms🦙, protein production services, and research tools🔬advancing #LifeScience & #Biomedicine.
Fantastic talk of @ewerslab.bsky.social with ExM data on Septins and Unroof Cells in #GEF25!
September 28, 2025 at 7:35 AM
Fantastic talk of @ewerslab.bsky.social with ExM data on Septins and Unroof Cells in #GEF25!
Reposted by Felipe Opazo
🦙 NanoTag at #SingleDomainAntibodies Conference 2025!
Our CEO Hansjörg Götzke will be in Utrecht sharing how our immune & synthetic sdAb platforms drive advances in research, diagnostics & therapeutics.
Our founder Felipe Opazo @opazo.bsky.social will also be there to connect & share insights.
Our CEO Hansjörg Götzke will be in Utrecht sharing how our immune & synthetic sdAb platforms drive advances in research, diagnostics & therapeutics.
Our founder Felipe Opazo @opazo.bsky.social will also be there to connect & share insights.
September 25, 2025 at 9:22 AM
🦙 NanoTag at #SingleDomainAntibodies Conference 2025!
Our CEO Hansjörg Götzke will be in Utrecht sharing how our immune & synthetic sdAb platforms drive advances in research, diagnostics & therapeutics.
Our founder Felipe Opazo @opazo.bsky.social will also be there to connect & share insights.
Our CEO Hansjörg Götzke will be in Utrecht sharing how our immune & synthetic sdAb platforms drive advances in research, diagnostics & therapeutics.
Our founder Felipe Opazo @opazo.bsky.social will also be there to connect & share insights.
Reposted by Felipe Opazo
#ExM turned 10 this year - just like #NanoTag! 🎉
Join us & the super-resolution community in Göttingen for the ExM Forum! 🔬Hear from our founder Felipe Opazo @opazo.bsky.social and CSO Steffen Frey on how NanoTag’s sdAb solutions empower nanoscopy & #multiplex imaging.
See you in Göttingen!
#GEF25
Join us & the super-resolution community in Göttingen for the ExM Forum! 🔬Hear from our founder Felipe Opazo @opazo.bsky.social and CSO Steffen Frey on how NanoTag’s sdAb solutions empower nanoscopy & #multiplex imaging.
See you in Göttingen!
#GEF25
September 17, 2025 at 8:33 AM
#ExM turned 10 this year - just like #NanoTag! 🎉
Join us & the super-resolution community in Göttingen for the ExM Forum! 🔬Hear from our founder Felipe Opazo @opazo.bsky.social and CSO Steffen Frey on how NanoTag’s sdAb solutions empower nanoscopy & #multiplex imaging.
See you in Göttingen!
#GEF25
Join us & the super-resolution community in Göttingen for the ExM Forum! 🔬Hear from our founder Felipe Opazo @opazo.bsky.social and CSO Steffen Frey on how NanoTag’s sdAb solutions empower nanoscopy & #multiplex imaging.
See you in Göttingen!
#GEF25
Reposted by Felipe Opazo
Prefusion gB of HSV bound with a neutralizing nanobody www.nature.com/articles/s41...
A nanobody specific to prefusion glycoprotein B neutralizes HSV-1 and HSV-2 - Nature
A neutralizing nanobody specific to the prefusion conformation of herpes simplex virus glycoprotein B has cross-species activity and offers insights into virus neutralization, possible immunogens and ...
www.nature.com
September 4, 2025 at 5:51 AM
Prefusion gB of HSV bound with a neutralizing nanobody www.nature.com/articles/s41...
Reposted by Felipe Opazo
🔬Wrapping up #SMLMS2025 @smlm-symposium.bsky.social in Bonn! Thanks to everyone who stopped by our booth!
It was great connecting and sharing how our #sdAb-based solutions enhance precision, simplify #Multiplexing, and streamline workflows in #SuperResolution microscopy.
See you next year! 🦙
It was great connecting and sharing how our #sdAb-based solutions enhance precision, simplify #Multiplexing, and streamline workflows in #SuperResolution microscopy.
See you next year! 🦙
August 29, 2025 at 11:33 AM
🔬Wrapping up #SMLMS2025 @smlm-symposium.bsky.social in Bonn! Thanks to everyone who stopped by our booth!
It was great connecting and sharing how our #sdAb-based solutions enhance precision, simplify #Multiplexing, and streamline workflows in #SuperResolution microscopy.
See you next year! 🦙
It was great connecting and sharing how our #sdAb-based solutions enhance precision, simplify #Multiplexing, and streamline workflows in #SuperResolution microscopy.
See you next year! 🦙
Reposted by Felipe Opazo
Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
August 21, 2025 at 5:19 AM
Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
🧬 New paper out! We explored why #antibodies have kept their 2 binding sites. Turns out, this “divalence” is crucial for B-cell receptors to sense antigen clustering and trigger immune responses, especially for weak or low-density antigens.
Check full text: doi.org/10.1038/s414...
Check full text: doi.org/10.1038/s414...
August 11, 2025 at 12:44 PM
🧬 New paper out! We explored why #antibodies have kept their 2 binding sites. Turns out, this “divalence” is crucial for B-cell receptors to sense antigen clustering and trigger immune responses, especially for weak or low-density antigens.
Check full text: doi.org/10.1038/s414...
Check full text: doi.org/10.1038/s414...
Reposted by Felipe Opazo
- A postdoc to work on cancer extravasation (4-year project).
- A postdoc help in completing Filopodia-related lab projects (2-year).
- Multiple Marie Curie postdoc positions that will open in the fall.
- We will open a 5-year position to cover my teaching (70% research and 30% teaching).
- A postdoc help in completing Filopodia-related lab projects (2-year).
- Multiple Marie Curie postdoc positions that will open in the fall.
- We will open a 5-year position to cover my teaching (70% research and 30% teaching).
Are you looking for a postdoc?
I will be looking for 2-4 people after the summer to join the lab !!
Do not hesitate to reach out and disseminate !!
I will be looking for 2-4 people after the summer to join the lab !!
Do not hesitate to reach out and disseminate !!
July 1, 2025 at 4:46 AM
- A postdoc to work on cancer extravasation (4-year project).
- A postdoc help in completing Filopodia-related lab projects (2-year).
- Multiple Marie Curie postdoc positions that will open in the fall.
- We will open a 5-year position to cover my teaching (70% research and 30% teaching).
- A postdoc help in completing Filopodia-related lab projects (2-year).
- Multiple Marie Curie postdoc positions that will open in the fall.
- We will open a 5-year position to cover my teaching (70% research and 30% teaching).
Reposted by Felipe Opazo
🌞🦙 Summer makeover? You bet.
Our alpacas ditched the fleece to stay cool – maybe your antibodies should too.
sdAbs are high-performance tools made of just the antigen-binding domain (∼15 kDa, 3 nm). 🔬🧪Perfect for IF, super-resolution microscopy, IP & more.
Browse our #nanobodies: nano-tag.com/shop/
Our alpacas ditched the fleece to stay cool – maybe your antibodies should too.
sdAbs are high-performance tools made of just the antigen-binding domain (∼15 kDa, 3 nm). 🔬🧪Perfect for IF, super-resolution microscopy, IP & more.
Browse our #nanobodies: nano-tag.com/shop/
June 11, 2025 at 10:27 AM
🌞🦙 Summer makeover? You bet.
Our alpacas ditched the fleece to stay cool – maybe your antibodies should too.
sdAbs are high-performance tools made of just the antigen-binding domain (∼15 kDa, 3 nm). 🔬🧪Perfect for IF, super-resolution microscopy, IP & more.
Browse our #nanobodies: nano-tag.com/shop/
Our alpacas ditched the fleece to stay cool – maybe your antibodies should too.
sdAbs are high-performance tools made of just the antigen-binding domain (∼15 kDa, 3 nm). 🔬🧪Perfect for IF, super-resolution microscopy, IP & more.
Browse our #nanobodies: nano-tag.com/shop/
Reposted by Felipe Opazo
💬Thank you, Dr. Maja Klevanski @majaklevanski.bsky.social (University of Heidelberg), for the great feedback on our recombinant anti-SARS-CoV-2 S1 antibody (rHcAb)! 😊 🔬 Applied in #dSTORM to study virion–cell interactions under antiviral conditions. Learn more about sdAb–Fc fusions 👉 bit.ly/3xdhYsn
June 4, 2025 at 8:44 AM
💬Thank you, Dr. Maja Klevanski @majaklevanski.bsky.social (University of Heidelberg), for the great feedback on our recombinant anti-SARS-CoV-2 S1 antibody (rHcAb)! 😊 🔬 Applied in #dSTORM to study virion–cell interactions under antiviral conditions. Learn more about sdAb–Fc fusions 👉 bit.ly/3xdhYsn
Reposted by Felipe Opazo
🤹♀️ Still juggling primary antibodies from different species?
Still stuck in sequential staining?
⏱️Switch to Smart Secondaries®🦙:
✅OneStep-IF
✅Same-species #multiplexing
✅Higher precision & reproducibility!
Choose smart 👉 bit.ly/3UZxRMI
#SecondaryNanobody #Microscopy #Immunofluorescence
Still stuck in sequential staining?
⏱️Switch to Smart Secondaries®🦙:
✅OneStep-IF
✅Same-species #multiplexing
✅Higher precision & reproducibility!
Choose smart 👉 bit.ly/3UZxRMI
#SecondaryNanobody #Microscopy #Immunofluorescence
May 28, 2025 at 12:30 PM
🤹♀️ Still juggling primary antibodies from different species?
Still stuck in sequential staining?
⏱️Switch to Smart Secondaries®🦙:
✅OneStep-IF
✅Same-species #multiplexing
✅Higher precision & reproducibility!
Choose smart 👉 bit.ly/3UZxRMI
#SecondaryNanobody #Microscopy #Immunofluorescence
Still stuck in sequential staining?
⏱️Switch to Smart Secondaries®🦙:
✅OneStep-IF
✅Same-species #multiplexing
✅Higher precision & reproducibility!
Choose smart 👉 bit.ly/3UZxRMI
#SecondaryNanobody #Microscopy #Immunofluorescence
Reposted by Felipe Opazo
@abberior.rocks — and NanoTag Biotechnologies rocks with them! 🤘
Smart Secondaries® 🦙now conjugated to abberior STAR dyes 🌈. Discover brighter, sharper, #STED -ready, species-independent #multiplexing & one-step IF. 🔬🤩
#SecondaryNanobodies
#SuperResolution
#FluorescenceMicroscopy
Smart Secondaries® 🦙now conjugated to abberior STAR dyes 🌈. Discover brighter, sharper, #STED -ready, species-independent #multiplexing & one-step IF. 🔬🤩
#SecondaryNanobodies
#SuperResolution
#FluorescenceMicroscopy
🔬 Small size, big impact – abberior STAR dyes meet Smart Secondaries® from NanoTag Biotechnologies @nanotag.bsky.social
We’re excited to launch bright, photostable, STED-optimized STAR dyes conjugated to high-precision single-domain antibodies (sdAbs, nanobodies).
#nanobodies #abberiordyes #STED
We’re excited to launch bright, photostable, STED-optimized STAR dyes conjugated to high-precision single-domain antibodies (sdAbs, nanobodies).
#nanobodies #abberiordyes #STED
May 20, 2025 at 2:04 PM
@abberior.rocks — and NanoTag Biotechnologies rocks with them! 🤘
Smart Secondaries® 🦙now conjugated to abberior STAR dyes 🌈. Discover brighter, sharper, #STED -ready, species-independent #multiplexing & one-step IF. 🔬🤩
#SecondaryNanobodies
#SuperResolution
#FluorescenceMicroscopy
Smart Secondaries® 🦙now conjugated to abberior STAR dyes 🌈. Discover brighter, sharper, #STED -ready, species-independent #multiplexing & one-step IF. 🔬🤩
#SecondaryNanobodies
#SuperResolution
#FluorescenceMicroscopy
Reposted by Felipe Opazo
Preprint: IntAct-U-ExM enables robust, isoform-specific expansion microscopy of actin networks in yeast and mammalian cells. A cool study led by @anubhavdhar.bsky.social in collaboration with Sudarshan and Deepak Nair. www.biorxiv.org/content/10.1...
May 16, 2025 at 8:00 AM
Preprint: IntAct-U-ExM enables robust, isoform-specific expansion microscopy of actin networks in yeast and mammalian cells. A cool study led by @anubhavdhar.bsky.social in collaboration with Sudarshan and Deepak Nair. www.biorxiv.org/content/10.1...
Reposted by Felipe Opazo
A new study by @jungmannlab.bsky.social presents #SPINNA, a model-based tool for quantifying protein stoichiometry, oligomerization state, and spatial arrangement from super-resolution data.🔬For precise labeling of #GFP & #mCherry fusion proteins researchers used our #nanobodies 😊
📄 bit.ly/4jTHfes
📄 bit.ly/4jTHfes
Spatial and stoichiometric in situ analysis of biomolecular oligomerization at single-protein resolution - Nature Communications
Extracting quantitative information on biomolecular oligomerisation with high resolution remains a significant challenge. Here, the authors propose SPINNA, a framework that compares nearest-neighbour ...
bit.ly
May 13, 2025 at 10:12 AM
A new study by @jungmannlab.bsky.social presents #SPINNA, a model-based tool for quantifying protein stoichiometry, oligomerization state, and spatial arrangement from super-resolution data.🔬For precise labeling of #GFP & #mCherry fusion proteins researchers used our #nanobodies 😊
📄 bit.ly/4jTHfes
📄 bit.ly/4jTHfes
Reposted by Felipe Opazo
Please welcome our official #mesoSPIM channel on this platform, @mesospim.bsky.social. Repost is appreciated!
January 20, 2025 at 10:22 AM
Please welcome our official #mesoSPIM channel on this platform, @mesospim.bsky.social. Repost is appreciated!
Reposted by Felipe Opazo
Fun fact: Alpacas love dust baths! 🦙💨
Spring at our farm means blossoms, sun & lots of happy rolling in the sand 🌸☀️
Just like our alpacas enjoy a refreshing dust bath, our clients enjoy smooth #sdAb discovery.
Let’s roll into new discoveries together 🙃!
#NanoTag #VHH #nanobody #AlpacaAntibodies
Spring at our farm means blossoms, sun & lots of happy rolling in the sand 🌸☀️
Just like our alpacas enjoy a refreshing dust bath, our clients enjoy smooth #sdAb discovery.
Let’s roll into new discoveries together 🙃!
#NanoTag #VHH #nanobody #AlpacaAntibodies
May 6, 2025 at 8:30 AM
Fun fact: Alpacas love dust baths! 🦙💨
Spring at our farm means blossoms, sun & lots of happy rolling in the sand 🌸☀️
Just like our alpacas enjoy a refreshing dust bath, our clients enjoy smooth #sdAb discovery.
Let’s roll into new discoveries together 🙃!
#NanoTag #VHH #nanobody #AlpacaAntibodies
Spring at our farm means blossoms, sun & lots of happy rolling in the sand 🌸☀️
Just like our alpacas enjoy a refreshing dust bath, our clients enjoy smooth #sdAb discovery.
Let’s roll into new discoveries together 🙃!
#NanoTag #VHH #nanobody #AlpacaAntibodies
Reposted by Felipe Opazo
Very excited to present our latest work: SPINNA, an analysis framework and software package for single-protein resolution data! 🖥️🤩
We can directly quantify stoichiometry and oligomerization from super-res (DNA-PAINT, RESI) images!! 🧬🎨
We can directly quantify stoichiometry and oligomerization from super-res (DNA-PAINT, RESI) images!! 🧬🎨
Spatial and stoichiometric in situ analysis of biomolecular oligomerization at single-protein resolution
We are excited to present our latest work published in @natcomms.nature.com
www.nature.com/articles/s41...
We are excited to present our latest work published in @natcomms.nature.com
www.nature.com/articles/s41...
Spatial and stoichiometric in situ analysis of biomolecular oligomerization at single-protein resolution - Nature Communications
Extracting quantitative information on biomolecular oligomerisation with high resolution remains a significant challenge. Here, the authors propose SPINNA, a framework that compares nearest-neighbour ...
www.nature.com
May 7, 2025 at 2:56 PM
Very excited to present our latest work: SPINNA, an analysis framework and software package for single-protein resolution data! 🖥️🤩
We can directly quantify stoichiometry and oligomerization from super-res (DNA-PAINT, RESI) images!! 🧬🎨
We can directly quantify stoichiometry and oligomerization from super-res (DNA-PAINT, RESI) images!! 🧬🎨
Reposted by Felipe Opazo
🚀 New: sdAb anti-Human #IgG!
Expanding our #Smart Secondaries® (secondary #nanobodies) range with high-specificity sdAb clones for precise Human IgG detection. Minimized linkage error, superior penetration, ideal for one-step IF, ELISA, WB & therapeutic Ab testing. 👉 bit.ly/4ia1H9B
Expanding our #Smart Secondaries® (secondary #nanobodies) range with high-specificity sdAb clones for precise Human IgG detection. Minimized linkage error, superior penetration, ideal for one-step IF, ELISA, WB & therapeutic Ab testing. 👉 bit.ly/4ia1H9B
April 29, 2025 at 5:02 PM
🚀 New: sdAb anti-Human #IgG!
Expanding our #Smart Secondaries® (secondary #nanobodies) range with high-specificity sdAb clones for precise Human IgG detection. Minimized linkage error, superior penetration, ideal for one-step IF, ELISA, WB & therapeutic Ab testing. 👉 bit.ly/4ia1H9B
Expanding our #Smart Secondaries® (secondary #nanobodies) range with high-specificity sdAb clones for precise Human IgG detection. Minimized linkage error, superior penetration, ideal for one-step IF, ELISA, WB & therapeutic Ab testing. 👉 bit.ly/4ia1H9B
Reposted by Felipe Opazo
Finally a role for the most common synaptic marker in the world synaptophysin - maintaining synaptic vesicle diameter: www.science.org/doi/10.1126/...
Synaptophysin accelerates synaptic vesicle fusion by expanding the membrane upon neurotransmitter loading
Synaptophysin allows synaptic vesicles to expand during loading with neurotransmitters, resulting in faster fusion.
www.science.org
April 27, 2025 at 12:23 AM
Finally a role for the most common synaptic marker in the world synaptophysin - maintaining synaptic vesicle diameter: www.science.org/doi/10.1126/...
Reposted by Felipe Opazo
Excited for our latest work! We developed nanobinders for the luminal domain of Synaptotagmin 1 (calcium sensor for synaptic vesicles). Thanks among others to @verstrekenlab.bsky.social @opazo.bsky.social @meunierlab.bsky.social @volkerhaucke-lab.bsky.social www.biorxiv.org/content/10.1...
Nanobinders for Synaptotagmin 1 enable the analysis of synaptic vesicle dynamics in rodent and human models.
Synaptic neurotransmission is a critical hallmark of brain activity and one of the first processes to be affected in neural diseases. Monitoring this process, and in particular synaptic vesicle recycl...
www.biorxiv.org
April 22, 2025 at 9:27 AM
Excited for our latest work! We developed nanobinders for the luminal domain of Synaptotagmin 1 (calcium sensor for synaptic vesicles). Thanks among others to @verstrekenlab.bsky.social @opazo.bsky.social @meunierlab.bsky.social @volkerhaucke-lab.bsky.social www.biorxiv.org/content/10.1...
Reposted by Felipe Opazo
Our lab at the NIH (Bethesda, MD) is looking for postdoctoral fellows to join our team studying the molecular mechanisms of protein trafficking and their links to neurodevelopmental disorders starting on or after 10-1-2025. Send your application to juan.bonifacino@nih.gov. Please share and repost!
April 13, 2025 at 4:37 PM
Our lab at the NIH (Bethesda, MD) is looking for postdoctoral fellows to join our team studying the molecular mechanisms of protein trafficking and their links to neurodevelopmental disorders starting on or after 10-1-2025. Send your application to juan.bonifacino@nih.gov. Please share and repost!
I am very excited about the invitation of @petrikursula.bsky.social to give a seminar at the Uni Bergen (UiB) 🇳🇴. I’ll share some of our work using @nanotag.bsky.social engineered #nanobodies with erasable signals for multiplexing microscopy. Paper: lnkd.in/een2yCDx Seminar: lnkd.in/esNGXhiv
April 8, 2025 at 2:07 PM
I am very excited about the invitation of @petrikursula.bsky.social to give a seminar at the Uni Bergen (UiB) 🇳🇴. I’ll share some of our work using @nanotag.bsky.social engineered #nanobodies with erasable signals for multiplexing microscopy. Paper: lnkd.in/een2yCDx Seminar: lnkd.in/esNGXhiv
Reposted by Felipe Opazo
We had a blast hosting curious young minds at NanoTag Biotechnologies for #Zukunftstag2025! From alpacas to #nanobodies, pipetting, microscopy, and liquid nitrogen fun❄️ 🌹with team from myriamed — science, teamwork, and discovery were in the spotlight! 🔬🧪🦙 #FutureDay2025 #ScienceIsFun #BiotechCareers
April 4, 2025 at 6:53 AM
We had a blast hosting curious young minds at NanoTag Biotechnologies for #Zukunftstag2025! From alpacas to #nanobodies, pipetting, microscopy, and liquid nitrogen fun❄️ 🌹with team from myriamed — science, teamwork, and discovery were in the spotlight! 🔬🧪🦙 #FutureDay2025 #ScienceIsFun #BiotechCareers