André Nadler
@nadlerlab.bsky.social
Chemist in a CellBio place. Fan of lipids & membranes
Pinned
André Nadler
@nadlerlab.bsky.social
· Aug 21
Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by André Nadler
📣 Please spread: we’re hiring a Lab Manager! It is a critical position in our new lab. As our lab moves to Barcelona and joins the @crg.eu, we’re looking for a Lab Manager to help build the lab and set the lab atmosphere.
🔗 Apply here 👉 recruitment.crg.eu/content/jobs...
🔗 Apply here 👉 recruitment.crg.eu/content/jobs...
January 23, 2026 at 6:41 AM
📣 Please spread: we’re hiring a Lab Manager! It is a critical position in our new lab. As our lab moves to Barcelona and joins the @crg.eu, we’re looking for a Lab Manager to help build the lab and set the lab atmosphere.
🔗 Apply here 👉 recruitment.crg.eu/content/jobs...
🔗 Apply here 👉 recruitment.crg.eu/content/jobs...
Reposted by André Nadler
Congratulations to Rashmi and Karolina and also to the technology development studio of the MPI-CBG without whom the screen would not have been possible.
If you are interested in high-content screening in organoid models, you may want to take a look.
If you are interested in high-content screening in organoid models, you may want to take a look.
The group of @anne-grapin.bsky.social developed methods to create functional acinar cells, which are involved in the formation of pancreatic cancer. Rashmiparvathi Keshara, Karolina Kuodyte, and the TDS facility used image-based screen & robust analysis pipeline. www.mpi-cbg.de/news-outreac...
Making human pancreatic acinar cells
Dresden researchers develop novel methods to create acinar cells, which are involved in the formation of pancreatic cancer.
www.mpi-cbg.de
January 22, 2026 at 2:04 PM
Congratulations to Rashmi and Karolina and also to the technology development studio of the MPI-CBG without whom the screen would not have been possible.
If you are interested in high-content screening in organoid models, you may want to take a look.
If you are interested in high-content screening in organoid models, you may want to take a look.
Reposted by André Nadler
The work by @danialv.bsky.social is now out in @pnas.org with a few changes after peer-review. Have a look if you are interested in lipid transport by bridge lipid transfer proteins (BLTPs)...
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
January 22, 2026 at 2:18 PM
The work by @danialv.bsky.social is now out in @pnas.org with a few changes after peer-review. Have a look if you are interested in lipid transport by bridge lipid transfer proteins (BLTPs)...
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Reposted by André Nadler
Expressions of interest: Director at MPI EvolBio (f/m/d) — We invite expressions of interest from distinguished scientists in evolutionary biology with a bold, long-term research vision that complements our Institute. More information: www.evolbio.mpg.de/3856225/Dire...
Directors
www.evolbio.mpg.de
January 21, 2026 at 11:15 AM
Expressions of interest: Director at MPI EvolBio (f/m/d) — We invite expressions of interest from distinguished scientists in evolutionary biology with a bold, long-term research vision that complements our Institute. More information: www.evolbio.mpg.de/3856225/Dire...
Reposted by André Nadler
Join us for the GBM Lunch on January 28 at 12:30 PM (CET)!
André Nadler & Kristin Böhlig @nadlerlab.bsky.social (@mpi-cbg.de) will speak on “Quantifying Intracellular Lipid Transport.”
Chair: Oliver Thorn-Seshold (TU Dresden)
Organizer: Joint Study Group "Chemical Biology"
#GBMLunch #ChemicalBiology
André Nadler & Kristin Böhlig @nadlerlab.bsky.social (@mpi-cbg.de) will speak on “Quantifying Intracellular Lipid Transport.”
Chair: Oliver Thorn-Seshold (TU Dresden)
Organizer: Joint Study Group "Chemical Biology"
#GBMLunch #ChemicalBiology
January 21, 2026 at 10:39 AM
Join us for the GBM Lunch on January 28 at 12:30 PM (CET)!
André Nadler & Kristin Böhlig @nadlerlab.bsky.social (@mpi-cbg.de) will speak on “Quantifying Intracellular Lipid Transport.”
Chair: Oliver Thorn-Seshold (TU Dresden)
Organizer: Joint Study Group "Chemical Biology"
#GBMLunch #ChemicalBiology
André Nadler & Kristin Böhlig @nadlerlab.bsky.social (@mpi-cbg.de) will speak on “Quantifying Intracellular Lipid Transport.”
Chair: Oliver Thorn-Seshold (TU Dresden)
Organizer: Joint Study Group "Chemical Biology"
#GBMLunch #ChemicalBiology
Reposted by André Nadler
Fantastic and snowy two-hour “evening constitutional” at the @mpipks.bsky.social Biological Physics retreat in Oberwiesenthal! Great chatting with Pierre @lepuslapis.bsky.social and Christina Kurzthaler
January 20, 2026 at 9:57 PM
Fantastic and snowy two-hour “evening constitutional” at the @mpipks.bsky.social Biological Physics retreat in Oberwiesenthal! Great chatting with Pierre @lepuslapis.bsky.social and Christina Kurzthaler
Reposted by André Nadler
Just got back from the traditional post-prandial constitutional at the @mpipks.bsky.social #biophysics retreat. Photo illustrates visibility on the slopes of the Fichtelberg and @larshubatsch.bsky.social trying to figure out whether we were still on a path...
January 20, 2026 at 9:49 PM
Just got back from the traditional post-prandial constitutional at the @mpipks.bsky.social #biophysics retreat. Photo illustrates visibility on the slopes of the Fichtelberg and @larshubatsch.bsky.social trying to figure out whether we were still on a path...
Reposted by André Nadler
Out now in @natchembio.nature.com: Xylosyltransferase engineering to manipulate proteoglycans in mammalian cells 🎉 www.nature.com/articles/s41... check out the press release below! #glycotime
January 20, 2026 at 11:08 AM
Out now in @natchembio.nature.com: Xylosyltransferase engineering to manipulate proteoglycans in mammalian cells 🎉 www.nature.com/articles/s41... check out the press release below! #glycotime
Reposted by André Nadler
#chembio and #bioorganic crowd. Mark your calendars for ESBOC 2026, registration opens soon!
www.esboc.org.uk
⏱️ 27th-30th May 2026
🏰 The beautiful Schlosshotel Pillnitz GmbH in Dresden/Germany
www.esboc.org.uk
⏱️ 27th-30th May 2026
🏰 The beautiful Schlosshotel Pillnitz GmbH in Dresden/Germany
ESBOC – European Symposium on Biological and Organic Chemistry
www.esboc.org.uk
January 18, 2026 at 8:53 PM
#chembio and #bioorganic crowd. Mark your calendars for ESBOC 2026, registration opens soon!
www.esboc.org.uk
⏱️ 27th-30th May 2026
🏰 The beautiful Schlosshotel Pillnitz GmbH in Dresden/Germany
www.esboc.org.uk
⏱️ 27th-30th May 2026
🏰 The beautiful Schlosshotel Pillnitz GmbH in Dresden/Germany
Reposted by André Nadler
Modern lipid biology has grown far beyond its roots. Advanced technologies offer novel opportunities to unravel the role of lipids in the organization of biological systems. Build on this momentum and join The EMBO Workshop "The Lipid Code to Life" Sept 7-11, 2026 meetings.embo.org/event/26-lip...
January 18, 2026 at 12:31 PM
Modern lipid biology has grown far beyond its roots. Advanced technologies offer novel opportunities to unravel the role of lipids in the organization of biological systems. Build on this momentum and join The EMBO Workshop "The Lipid Code to Life" Sept 7-11, 2026 meetings.embo.org/event/26-lip...
Reposted by André Nadler
A new paper by @thornsesholdlab.bsky.social reports photoswitchable ligands with wavelength-dependent, and concentration-independent, control of TRPC4/5 channels in live tissues
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Ideal efficacy photoswitching for chromocontrol of TRPC4/5 channel functions in live tissues - Nature Chemical Biology
Using chemical photoswitchable reagents to exert purely wavelength-dependent control over biological systems in deep tissue and in vivo requires a concentration-independent design paradigm. Here, such...
www.nature.com
January 16, 2026 at 8:46 PM
A new paper by @thornsesholdlab.bsky.social reports photoswitchable ligands with wavelength-dependent, and concentration-independent, control of TRPC4/5 channels in live tissues
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Do register! It is really worth it, I promise!
Have you registered yet? Early bird registration and abstract submission are open until January 31.
mosbacher-kolloquium.org
mosbacher-kolloquium.org
January 17, 2026 at 11:00 AM
Do register! It is really worth it, I promise!
Reposted by André Nadler
I want to highlight a new #lipidtime article from our lab on disease-associated 1-deoxysphingolipids, which is nicely featured on the cover of this month's issue of Cell Chem Bio @cp-cellchembiol.bsky.social www.cell.com/cell-chemica...
January 16, 2026 at 6:34 PM
I want to highlight a new #lipidtime article from our lab on disease-associated 1-deoxysphingolipids, which is nicely featured on the cover of this month's issue of Cell Chem Bio @cp-cellchembiol.bsky.social www.cell.com/cell-chemica...
Reposted by André Nadler
With so many great reviews on LDs already out, do we need another?
Sarah @cohenlaboratory.bsky.social and I were approached by
@natrevmcb.nature.com to do a review on LD heterogeneity and inter-organelle contacts...topics in reviews, but not a focus. Fun project!
www.nature.com/articles/s41...
Sarah @cohenlaboratory.bsky.social and I were approached by
@natrevmcb.nature.com to do a review on LD heterogeneity and inter-organelle contacts...topics in reviews, but not a focus. Fun project!
www.nature.com/articles/s41...
Heterogeneity, dynamics and organelle interactions of lipid droplets - Nature Reviews Molecular Cell Biology
Lipid droplets have key roles in energy storage and lipid metabolism. This Review discusses tools used for assessing lipid droplet heterogeneity, and how their heterogeneous composition and interactio...
www.nature.com
January 16, 2026 at 2:18 PM
With so many great reviews on LDs already out, do we need another?
Sarah @cohenlaboratory.bsky.social and I were approached by
@natrevmcb.nature.com to do a review on LD heterogeneity and inter-organelle contacts...topics in reviews, but not a focus. Fun project!
www.nature.com/articles/s41...
Sarah @cohenlaboratory.bsky.social and I were approached by
@natrevmcb.nature.com to do a review on LD heterogeneity and inter-organelle contacts...topics in reviews, but not a focus. Fun project!
www.nature.com/articles/s41...
Reposted by André Nadler
We are online! Apply, repost, inform all your amazing colleagues and lets have a great #lipidlove time in Dresden
meetings.embo.org/event/26-lip...
meetings.embo.org/event/26-lip...
January 15, 2026 at 12:36 PM
We are online! Apply, repost, inform all your amazing colleagues and lets have a great #lipidlove time in Dresden
meetings.embo.org/event/26-lip...
meetings.embo.org/event/26-lip...
Reposted by André Nadler
I wrote a post describing a minimal set of principles that I've been using to make my research papers a bit more reproducible. Would love hearing what you think! #OpenScience
brunovellutini.com/posts/daft-p...
brunovellutini.com/posts/daft-p...
DAFT: minimal principles for reproducible research papers - Bruno C. Vellutini
DAFT principles are a minimal set of principles I've been using to organize my research papers that foster good scientific practice.
brunovellutini.com
January 13, 2026 at 6:14 PM
I wrote a post describing a minimal set of principles that I've been using to make my research papers a bit more reproducible. Would love hearing what you think! #OpenScience
brunovellutini.com/posts/daft-p...
brunovellutini.com/posts/daft-p...
Reposted by André Nadler
Excited to share our first collaborative paper of the year- a review on the emerging roles of lipids in flavivirus infection, now published in @cp-trendsmicrobiol.bsky.social. Congrats to Judah (postdoc) for spearheading the work!
@ohsunews.bsky.social
www.sciencedirect.com/science/arti...
@ohsunews.bsky.social
www.sciencedirect.com/science/arti...
January 12, 2026 at 8:12 PM
Excited to share our first collaborative paper of the year- a review on the emerging roles of lipids in flavivirus infection, now published in @cp-trendsmicrobiol.bsky.social. Congrats to Judah (postdoc) for spearheading the work!
@ohsunews.bsky.social
www.sciencedirect.com/science/arti...
@ohsunews.bsky.social
www.sciencedirect.com/science/arti...
Reposted by André Nadler
Happy to finally share the amazing results of our long-term collaboration with Karin Reinisch’s lab on how bridge lipid-transfer proteins (BLTPs) cooperate with partner proteins to orchestrate lipid delivery. A quick thread (1/7)
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
January 12, 2026 at 7:57 PM
Happy to finally share the amazing results of our long-term collaboration with Karin Reinisch’s lab on how bridge lipid-transfer proteins (BLTPs) cooperate with partner proteins to orchestrate lipid delivery. A quick thread (1/7)
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Reposted by André Nadler
Years ago, I spent endless time to write hundreds of image processing filters so that they run on GPUs; resulting in the #clij library. Today, I asked claude to write the Kuwahara Filter in the CLIJ OpenCL dialect and it worked in the first attempt. Mind-blow-ing. 🤯
January 11, 2026 at 10:10 AM
Years ago, I spent endless time to write hundreds of image processing filters so that they run on GPUs; resulting in the #clij library. Today, I asked claude to write the Kuwahara Filter in the CLIJ OpenCL dialect and it worked in the first attempt. Mind-blow-ing. 🤯
Reposted by André Nadler
The #ChlamyDataset is on the cover of @cp-molcell.bsky.social 🖼️🥰!
Read @lifeonthewedge.bsky.social's great thread🧵 for the inside scoop🍨 on all the #TeamTomo developments already made possible since these 1829 tomos hit EMPIAR 🧪 🧶🧬
For more, here's the old preprint thread:
bsky.app/profile/cell...
Read @lifeonthewedge.bsky.social's great thread🧵 for the inside scoop🍨 on all the #TeamTomo developments already made possible since these 1829 tomos hit EMPIAR 🧪 🧶🧬
For more, here's the old preprint thread:
bsky.app/profile/cell...
This one was quite the journey! The paper describing the #ChlamyDataset is finally out and on the cover of Mol Cell!
This beautiful rendering made by co-author @jessheebner.bsky.social and Holly Peterson shows an instance of mitochondrial fission found in the dataset 😍
[Maybe long thread ahead]
This beautiful rendering made by co-author @jessheebner.bsky.social and Holly Peterson shows an instance of mitochondrial fission found in the dataset 😍
[Maybe long thread ahead]
January 9, 2026 at 7:49 PM
The #ChlamyDataset is on the cover of @cp-molcell.bsky.social 🖼️🥰!
Read @lifeonthewedge.bsky.social's great thread🧵 for the inside scoop🍨 on all the #TeamTomo developments already made possible since these 1829 tomos hit EMPIAR 🧪 🧶🧬
For more, here's the old preprint thread:
bsky.app/profile/cell...
Read @lifeonthewedge.bsky.social's great thread🧵 for the inside scoop🍨 on all the #TeamTomo developments already made possible since these 1829 tomos hit EMPIAR 🧪 🧶🧬
For more, here's the old preprint thread:
bsky.app/profile/cell...
Reposted by André Nadler
Congratulations to Byung Ho for spearheading this work and our HFSP team!
Curious about the formation of networks of thin lumens and some physics behind it? Take a look at the paper.
Byung Ho is looking for PI positions and he has amazing ideas and leadership.
www.nature.com/articles/s41...
Curious about the formation of networks of thin lumens and some physics behind it? Take a look at the paper.
Byung Ho is looking for PI positions and he has amazing ideas and leadership.
www.nature.com/articles/s41...
January 9, 2026 at 2:31 PM
Congratulations to Byung Ho for spearheading this work and our HFSP team!
Curious about the formation of networks of thin lumens and some physics behind it? Take a look at the paper.
Byung Ho is looking for PI positions and he has amazing ideas and leadership.
www.nature.com/articles/s41...
Curious about the formation of networks of thin lumens and some physics behind it? Take a look at the paper.
Byung Ho is looking for PI positions and he has amazing ideas and leadership.
www.nature.com/articles/s41...
Reposted by André Nadler
With Byung Ho Lee and Kana Fuji as first/lead authors, @anne-grapin.bsky.social group, @utokyoofficial.bsky.social, Inst. of Physics of Academia Sinica, & @igbmc.bsky.social found the shape of lumens in the developing pancreas is controlled by pressure & proliferation. www.mpi-cbg.de/news-outreac...
Engineering the development of the pancreas
Researchers found that the shape of the fluid-filled cavities in the developing pancreas is controlled by pressure and the rate cells divide.
www.mpi-cbg.de
January 9, 2026 at 12:17 PM
With Byung Ho Lee and Kana Fuji as first/lead authors, @anne-grapin.bsky.social group, @utokyoofficial.bsky.social, Inst. of Physics of Academia Sinica, & @igbmc.bsky.social found the shape of lumens in the developing pancreas is controlled by pressure & proliferation. www.mpi-cbg.de/news-outreac...
Reposted by André Nadler
It seems amazing naive to assume this condition of privacy will hold.
Most people (at least in academia) are not using private #AI chatbots.
Or am I missing something?
Most people (at least in academia) are not using private #AI chatbots.
Or am I missing something?
@dfg.de say AI reviewing allowed under 4 conditions.
I'm alarmed. The first, that neither the confidential contents of the grant nor the purpose of the query be saved by the AI provider, will not be obeyed by 95% of users.
Grant materials will become public!
Your ideas -> Chat -> The World 😭
I'm alarmed. The first, that neither the confidential contents of the grant nor the purpose of the query be saved by the AI provider, will not be obeyed by 95% of users.
Grant materials will become public!
Your ideas -> Chat -> The World 😭
January 9, 2026 at 10:30 AM
It seems amazing naive to assume this condition of privacy will hold.
Most people (at least in academia) are not using private #AI chatbots.
Or am I missing something?
Most people (at least in academia) are not using private #AI chatbots.
Or am I missing something?
Reposted by André Nadler
Snowy day @mpi-cbg.de and @csbdresden.bsky.social. ❄️❄️❄️
January 9, 2026 at 9:41 AM
Snowy day @mpi-cbg.de and @csbdresden.bsky.social. ❄️❄️❄️
This is a true wow-effect paper. You've got to read it. Amazing science - Congratulations Jan, Alison and everybody else!
Excited to share Alison's @alisonkickuth.bsky.social paper from the lab out in @nature.com this week! We uncovered how a mechanical ratchet mechanism drives cytokinesis in early #zebrafish embryos. Read more in this thread 🧵 and at www.nature.com/articles/s41... 🤩
@poldresden.bsky.social @mpi-cbg.de
@poldresden.bsky.social @mpi-cbg.de
January 8, 2026 at 4:03 PM
This is a true wow-effect paper. You've got to read it. Amazing science - Congratulations Jan, Alison and everybody else!