Bruno C. Vellutini
@bruvellu.bsky.social
Biologist interested in how embryonic development evolves #EvoDevo • Website: https://brunovellutini.com • Pronouns: he/him
Reposted by Bruno C. Vellutini
You can now search the entire EvoDevo Papers database (~1.8k posts). Check it out on the website evodevo.brunovellutini.com or read more here: brunovellutini.com/posts/evodev...
#EvoDevo #DevBio #EvoBio
#EvoDevo #DevBio #EvoBio
October 7, 2025 at 8:24 PM
You can now search the entire EvoDevo Papers database (~1.8k posts). Check it out on the website evodevo.brunovellutini.com or read more here: brunovellutini.com/posts/evodev...
#EvoDevo #DevBio #EvoBio
#EvoDevo #DevBio #EvoBio
The first steps of a sea urchin brunovellutini.com/posts/sea-ur...
The first steps of a sea urchin - Bruno C. Vellutini
The winners of this year's Nikon Small World in Motion are out, and my favorite is the 5th place entry, A newborn sea urchin walking along the seabed by
brunovellutini.com
September 29, 2025 at 7:47 PM
The first steps of a sea urchin brunovellutini.com/posts/sea-ur...
Reposted by Bruno C. Vellutini
Our new collaborative paper with Cyndi Bradham's lab at BU, led by first author @alexandralion.bsky.social is out in @devbiol.bsky.social & featured on the Sept 2025 cover! 😀🥳
PFAS (PFOA & GenX) disrupt sea urchin embryo development!
Cover art: embryos + flow fields
👉 doi.org/10.1016/j.yd...
PFAS (PFOA & GenX) disrupt sea urchin embryo development!
Cover art: embryos + flow fields
👉 doi.org/10.1016/j.yd...
September 17, 2025 at 8:21 PM
Our new collaborative paper with Cyndi Bradham's lab at BU, led by first author @alexandralion.bsky.social is out in @devbiol.bsky.social & featured on the Sept 2025 cover! 😀🥳
PFAS (PFOA & GenX) disrupt sea urchin embryo development!
Cover art: embryos + flow fields
👉 doi.org/10.1016/j.yd...
PFAS (PFOA & GenX) disrupt sea urchin embryo development!
Cover art: embryos + flow fields
👉 doi.org/10.1016/j.yd...
Reposted by Bruno C. Vellutini
BHL's future is uncertain, but hopeful. Securing its future requires new partners & sustained investment. For more information, follow along here & on the #BHLblog: blog.biodiversitylibrary.org/tag/transition. Help us safeguard the world’s collective biodiversity knowledge. #ILoveBHL 🧪 📖 🌱 🌏
September 12, 2025 at 12:38 AM
BHL's future is uncertain, but hopeful. Securing its future requires new partners & sustained investment. For more information, follow along here & on the #BHLblog: blog.biodiversitylibrary.org/tag/transition. Help us safeguard the world’s collective biodiversity knowledge. #ILoveBHL 🧪 📖 🌱 🌏
Reposted by Bruno C. Vellutini
Super thrilled to see our review out! It was a great experience to put this together with @sameerthukral.bsky.social and @yuchiunwang.bsky.social. Use it as a primer to the field or as inspiration to brainstorm how rigidity transitions can bridge scales!
Excited to share our new review in Development, Growth and Differentiation(DGD) Journall!
With the amazing @yuchiunwang.bsky.social & @bipashadey29.bsky.social,we explore how rigidity transitions bridge cytoplasmic & tissue scales.
Read the full review: onlinelibrary.wiley.com/doi/full/10....
With the amazing @yuchiunwang.bsky.social & @bipashadey29.bsky.social,we explore how rigidity transitions bridge cytoplasmic & tissue scales.
Read the full review: onlinelibrary.wiley.com/doi/full/10....
Integrating Tissue and Cytoplasmic Rigidity Transitions During Morphogenesis
Multicellular organisms generate organizational complexity through morphogenesis, in which mechanical forces orchestrate the movements and deformations of cells and tissues, while chemical signals re...
onlinelibrary.wiley.com
September 12, 2025 at 8:23 AM
Super thrilled to see our review out! It was a great experience to put this together with @sameerthukral.bsky.social and @yuchiunwang.bsky.social. Use it as a primer to the field or as inspiration to brainstorm how rigidity transitions can bridge scales!
Reposted by Bruno C. Vellutini
My opinion about the historic verdict coming out of Brazil, with @stevelevitsky.bsky.social, is in the @nytimes.com today.
www.nytimes.com/2025/09/12/o...
www.nytimes.com/2025/09/12/o...
Opinion | Brazil Just Succeeded Where the U.S. Failed
www.nytimes.com
September 12, 2025 at 10:18 AM
My opinion about the historic verdict coming out of Brazil, with @stevelevitsky.bsky.social, is in the @nytimes.com today.
www.nytimes.com/2025/09/12/o...
www.nytimes.com/2025/09/12/o...
Reposted by Bruno C. Vellutini
RIP Hermeto Pascoal, one of the greats! youtube.com/watch?v=TUdO...
Hermeto Pascoal & Grupo - Poré Poré (aka Renan) - Especial "Calendário do Som" - TV Cultura - 2001
YouTube video by Hermeto Pascoal
youtube.com
September 14, 2025 at 11:43 AM
RIP Hermeto Pascoal, one of the greats! youtube.com/watch?v=TUdO...
Reposted by Bruno C. Vellutini
Thanks a lot to @elisecutts.bsky.social for nicely highlighting and putting in context our article! It was very interesting to discuss together, notably about the analogies between the emergence of order in Hydra and other physical phenomena.
Hydra are ~basically~ immortal.
Shred 50 of the lil guys to bits and pack their cells in a blob, and that blob will grow into a new Hydra... albeit with a few extra heads!
This week's post is a Q&A @anaisbailles.bsky.social @mpi-cbg.de about the physics of how Hydra coax order from chaos.🧪⚛️
Shred 50 of the lil guys to bits and pack their cells in a blob, and that blob will grow into a new Hydra... albeit with a few extra heads!
This week's post is a Q&A @anaisbailles.bsky.social @mpi-cbg.de about the physics of how Hydra coax order from chaos.🧪⚛️
Hydra are a cosmos in a cuvette
Anaïs Bailles on astrophysics and immortal animals
www.reviewertoo.com
September 12, 2025 at 1:56 PM
Thanks a lot to @elisecutts.bsky.social for nicely highlighting and putting in context our article! It was very interesting to discuss together, notably about the analogies between the emergence of order in Hydra and other physical phenomena.
Reposted by Bruno C. Vellutini
Hydra are ~basically~ immortal.
Shred 50 of the lil guys to bits and pack their cells in a blob, and that blob will grow into a new Hydra... albeit with a few extra heads!
This week's post is a Q&A @anaisbailles.bsky.social @mpi-cbg.de about the physics of how Hydra coax order from chaos.🧪⚛️
Shred 50 of the lil guys to bits and pack their cells in a blob, and that blob will grow into a new Hydra... albeit with a few extra heads!
This week's post is a Q&A @anaisbailles.bsky.social @mpi-cbg.de about the physics of how Hydra coax order from chaos.🧪⚛️
Hydra are a cosmos in a cuvette
Anaïs Bailles on astrophysics and immortal animals
www.reviewertoo.com
September 11, 2025 at 5:49 PM
Hydra are ~basically~ immortal.
Shred 50 of the lil guys to bits and pack their cells in a blob, and that blob will grow into a new Hydra... albeit with a few extra heads!
This week's post is a Q&A @anaisbailles.bsky.social @mpi-cbg.de about the physics of how Hydra coax order from chaos.🧪⚛️
Shred 50 of the lil guys to bits and pack their cells in a blob, and that blob will grow into a new Hydra... albeit with a few extra heads!
This week's post is a Q&A @anaisbailles.bsky.social @mpi-cbg.de about the physics of how Hydra coax order from chaos.🧪⚛️
Reposted by Bruno C. Vellutini
I am very happy to announce that the Echinox Lab will open in the BIOM unit at @obs-banyuls.fr in January 2026!! 🥳
We will use several echinoderm species to study animal body plan evolution.
🔽 Check our brand new lab website if you want to learn more about our future research
www.echinox.org
We will use several echinoderm species to study animal body plan evolution.
🔽 Check our brand new lab website if you want to learn more about our future research
www.echinox.org
September 10, 2025 at 8:48 PM
I am very happy to announce that the Echinox Lab will open in the BIOM unit at @obs-banyuls.fr in January 2026!! 🥳
We will use several echinoderm species to study animal body plan evolution.
🔽 Check our brand new lab website if you want to learn more about our future research
www.echinox.org
We will use several echinoderm species to study animal body plan evolution.
🔽 Check our brand new lab website if you want to learn more about our future research
www.echinox.org
Reposted by Bruno C. Vellutini
Issue 16 is complete!
On the cover: Embryonic eye of an anole lizard stained for nuclei and F-actin. The image was acquired at the 2025 MBL Embryology course by Arthur Boutillon and was the Editor's choice from the Node image competition.
thenode.biologists.com/vote-for-you...
On the cover: Embryonic eye of an anole lizard stained for nuclei and F-actin. The image was acquired at the 2025 MBL Embryology course by Arthur Boutillon and was the Editor's choice from the Node image competition.
thenode.biologists.com/vote-for-you...
September 9, 2025 at 12:19 PM
Issue 16 is complete!
On the cover: Embryonic eye of an anole lizard stained for nuclei and F-actin. The image was acquired at the 2025 MBL Embryology course by Arthur Boutillon and was the Editor's choice from the Node image competition.
thenode.biologists.com/vote-for-you...
On the cover: Embryonic eye of an anole lizard stained for nuclei and F-actin. The image was acquired at the 2025 MBL Embryology course by Arthur Boutillon and was the Editor's choice from the Node image competition.
thenode.biologists.com/vote-for-you...
Reposted by Bruno C. Vellutini
Important story dissecting the mechanism of gut cell extrusion using organoids. Local heterogeneity of tension promotes live extrusion and basal relaxation is sufficient to kick the cell out. Nice combination of optogenetics and live imaging to demonstrate this
www.science.org/doi/abs/10.1...
www.science.org/doi/abs/10.1...
September 9, 2025 at 8:53 PM
Important story dissecting the mechanism of gut cell extrusion using organoids. Local heterogeneity of tension promotes live extrusion and basal relaxation is sufficient to kick the cell out. Nice combination of optogenetics and live imaging to demonstrate this
www.science.org/doi/abs/10.1...
www.science.org/doi/abs/10.1...
Reposted by Bruno C. Vellutini
New short paper from our lab @currentbiology.bsky.social, in which we discover of a new mode of cell motility for choanoflagellates: flagellar gliding. www.cell.com/current-biol... - A 🧵
Flagellar gliding in choanoflagellates
Freire-Delgado and Brunet discover a new mode of cell motility in choanoflagellates,
the closest relatives of animals. Under mild confinement, choanoflagellate move over
surfaces without cell deformat...
www.cell.com
September 9, 2025 at 6:12 PM
New short paper from our lab @currentbiology.bsky.social, in which we discover of a new mode of cell motility for choanoflagellates: flagellar gliding. www.cell.com/current-biol... - A 🧵
Reposted by Bruno C. Vellutini
Out now in Seminars in Cell & Dev Biol!
doi.org/10.1016/j.se...
With thanks to co-authors @callumbucklow.bsky.social and @bertaverd.bsky.social
doi.org/10.1016/j.se...
With thanks to co-authors @callumbucklow.bsky.social and @bertaverd.bsky.social
September 8, 2025 at 11:59 AM
Out now in Seminars in Cell & Dev Biol!
doi.org/10.1016/j.se...
With thanks to co-authors @callumbucklow.bsky.social and @bertaverd.bsky.social
doi.org/10.1016/j.se...
With thanks to co-authors @callumbucklow.bsky.social and @bertaverd.bsky.social
Reposted by Bruno C. Vellutini
Thrilled to share 🎉 I’m starting my lab at University of Zurich,
DMLS as Assistant Professor (tenure track) from Jan 2026!
The Neural MorphoGenomics & Developmental Dynamics Lab will be exploring how genes + morphogenesis shape brain development with organoids, imaging & spatial genomics 🧠🔬🧬
DMLS as Assistant Professor (tenure track) from Jan 2026!
The Neural MorphoGenomics & Developmental Dynamics Lab will be exploring how genes + morphogenesis shape brain development with organoids, imaging & spatial genomics 🧠🔬🧬
September 3, 2025 at 10:43 PM
Thrilled to share 🎉 I’m starting my lab at University of Zurich,
DMLS as Assistant Professor (tenure track) from Jan 2026!
The Neural MorphoGenomics & Developmental Dynamics Lab will be exploring how genes + morphogenesis shape brain development with organoids, imaging & spatial genomics 🧠🔬🧬
DMLS as Assistant Professor (tenure track) from Jan 2026!
The Neural MorphoGenomics & Developmental Dynamics Lab will be exploring how genes + morphogenesis shape brain development with organoids, imaging & spatial genomics 🧠🔬🧬
Reposted by Bruno C. Vellutini
🥳 Congratulations to our postdoc, Dr. Anna Czarkwiani @aniaczark.bsky.social, on receiving the ERC Starting Grant @erc.europa.eu!
With €2 million in funding, Anna will explore the biology of gravisensation and uncover insights into related disorders. 🧠
#CMCBnews @tudresden.bsky.social #ERCStG
With €2 million in funding, Anna will explore the biology of gravisensation and uncover insights into related disorders. 🧠
#CMCBnews @tudresden.bsky.social #ERCStG
September 4, 2025 at 10:13 AM
🥳 Congratulations to our postdoc, Dr. Anna Czarkwiani @aniaczark.bsky.social, on receiving the ERC Starting Grant @erc.europa.eu!
With €2 million in funding, Anna will explore the biology of gravisensation and uncover insights into related disorders. 🧠
#CMCBnews @tudresden.bsky.social #ERCStG
With €2 million in funding, Anna will explore the biology of gravisensation and uncover insights into related disorders. 🧠
#CMCBnews @tudresden.bsky.social #ERCStG
Reposted by Bruno C. Vellutini
Tissue 'tectonic' collision is detrimental, but flies found two distinct solutions! Gratifying and grateful to be included in this collective effort, w/ Steffen Lemke, to crack the (or 'a') code of #cephalicfurrow, now out in @nature.com, all with @paveltomancak.bsky.social at the helm. (1/9)
September 4, 2025 at 5:18 PM
Tissue 'tectonic' collision is detrimental, but flies found two distinct solutions! Gratifying and grateful to be included in this collective effort, w/ Steffen Lemke, to crack the (or 'a') code of #cephalicfurrow, now out in @nature.com, all with @paveltomancak.bsky.social at the helm. (1/9)
Reposted by Bruno C. Vellutini
Beautiful story that combined mechanobiology, evolution, and the power of fly (opto)genetics to make sense of the cephalic furrow. It was a pleasure writing the News & Views. No doubt this is still just the beginning for the field of mechano-evo-devo! Hats off to all involved
We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)
September 4, 2025 at 8:48 AM
Beautiful story that combined mechanobiology, evolution, and the power of fly (opto)genetics to make sense of the cephalic furrow. It was a pleasure writing the News & Views. No doubt this is still just the beginning for the field of mechano-evo-devo! Hats off to all involved
Reposted by Bruno C. Vellutini
The papers have been improved by reviewers @amartinezarias.bsky.social, @thibautbrunet.bsky.social & Cassandra Extavour. Thibaut synthesized the work beautifully in the #News_and_Views. None of that can happen without The Editor: @endofthepier.bsky.social (11/12)
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Flies evolved a shock-absorber tissue used during embryonic development
The role of tissue that forms between the head and trunk of a fly embryo has been unclear. It turns out that it absorbs forces when nearby cells move and divide.
www.nature.com
September 4, 2025 at 8:22 AM
The papers have been improved by reviewers @amartinezarias.bsky.social, @thibautbrunet.bsky.social & Cassandra Extavour. Thibaut synthesized the work beautifully in the #News_and_Views. None of that can happen without The Editor: @endofthepier.bsky.social (11/12)
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Reposted by Bruno C. Vellutini
We had #four interdisciplinary teams, integrating dev-bio, evolution, tissue mechanics, and biophysical modeling, all going full throttle to understand the #CF. Still, it took more than 7 years to publish two papers back-to-back (10/12)
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Patterned invagination prevents mechanical instability during gastrulation - Nature
In Drosophila, the cephalic furrow counteracts mechanical stress as the developing head and the trunk tissues meet, providing evidence for how mechanical forces influence the evolution of morphog...
www.nature.com
September 4, 2025 at 8:22 AM
We had #four interdisciplinary teams, integrating dev-bio, evolution, tissue mechanics, and biophysical modeling, all going full throttle to understand the #CF. Still, it took more than 7 years to publish two papers back-to-back (10/12)
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
So happy to see the cephalic furrow combo out back-to-back! This was a wonderful collaborative endeavor 🥹
We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)
September 4, 2025 at 1:17 PM
So happy to see the cephalic furrow combo out back-to-back! This was a wonderful collaborative endeavor 🥹
Reposted by Bruno C. Vellutini
Dresden researchers @paveltomancak.bsky.social @bruvellu.bsky.social, Carl Modes, @cuencam15.bsky.social & colleagues published in @nature.com that a tissue fold in fruit fly embryos buffers mechanical stresses & may have evolved in response to mechanical forces. www.mpi-cbg.de/news-outreac...
Mechanical forces drive evolutionary change
A small tissue fold present in fruit fly embryos buffers mechanical stresses and may have evolved in response to mechanical forces.
www.mpi-cbg.de
September 3, 2025 at 3:26 PM
Dresden researchers @paveltomancak.bsky.social @bruvellu.bsky.social, Carl Modes, @cuencam15.bsky.social & colleagues published in @nature.com that a tissue fold in fruit fly embryos buffers mechanical stresses & may have evolved in response to mechanical forces. www.mpi-cbg.de/news-outreac...
Reposted by Bruno C. Vellutini
I am thrilled to share the main result of our work at @nordenlab.bsky.social with @liormoneta.bsky.social and @carldmodes.bsky.social . We bridged DevBiology + theoretical physics to understand how the eye becomes round #morphogenesis #devbio #biophysics #zebrafish www.biorxiv.org/content/10.1...
The Optic cup is actively shape programmed by independently patterned apical forces
During morphogenesis, initially flat tissues often must transition into complex 3D shapes, reminiscent of shape-programmable systems in physics and engineering. One key question in developmental biolo...
www.biorxiv.org
September 1, 2025 at 9:22 PM
I am thrilled to share the main result of our work at @nordenlab.bsky.social with @liormoneta.bsky.social and @carldmodes.bsky.social . We bridged DevBiology + theoretical physics to understand how the eye becomes round #morphogenesis #devbio #biophysics #zebrafish www.biorxiv.org/content/10.1...
Reposted by Bruno C. Vellutini
The community of Drosophila researchers is amazing, mutually supportive and collaborative. Right now a key resource for our community, @flybase.bsky.social , is threatened by the cancellation of its NIH grant and is seeking community help in raising short term funds 1/n 🧪 please share
August 23, 2025 at 12:18 PM
The community of Drosophila researchers is amazing, mutually supportive and collaborative. Right now a key resource for our community, @flybase.bsky.social , is threatened by the cancellation of its NIH grant and is seeking community help in raising short term funds 1/n 🧪 please share
Reposted by Bruno C. Vellutini
A reminder you/your lab can support FlyBase at Cambridge through the following link. Every bit helps. Please share if you yourself can't donate.
www.philanthropy.cam.ac.uk/give-to-camb...
www.philanthropy.cam.ac.uk/give-to-camb...
August 14, 2025 at 5:25 AM
A reminder you/your lab can support FlyBase at Cambridge through the following link. Every bit helps. Please share if you yourself can't donate.
www.philanthropy.cam.ac.uk/give-to-camb...
www.philanthropy.cam.ac.uk/give-to-camb...