Michael Hoffman
@michaelhoffman.bsky.social
Chair, Computational BIology and Medicine Program, Princess Margaret Cancer Centre, University Health Network.
Associate Professor, Medical Biophysics, University of Toronto.
Disclosures: https://github.com/michaelmhoffman/disclosure/
Associate Professor, Medical Biophysics, University of Toronto.
Disclosures: https://github.com/michaelmhoffman/disclosure/
Pinned
Reposted by Michael Hoffman
As of this morning, it is imperative that the Democratic caucus in the senate remove Schumer as Minority Leader, Durbin as minority whip and Cortez Masto as Vice Chair of Outreach.
Replace them today with Van Hollen, Murphy and Merkley. Or anyone else who actually knows how to lead and discipline.
Replace them today with Van Hollen, Murphy and Merkley. Or anyone else who actually knows how to lead and discipline.
November 10, 2025 at 2:58 PM
As of this morning, it is imperative that the Democratic caucus in the senate remove Schumer as Minority Leader, Durbin as minority whip and Cortez Masto as Vice Chair of Outreach.
Replace them today with Van Hollen, Murphy and Merkley. Or anyone else who actually knows how to lead and discipline.
Replace them today with Van Hollen, Murphy and Merkley. Or anyone else who actually knows how to lead and discipline.
Reposted by Michael Hoffman
🌍Open call: Junior Group Leader positions!
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
November 10, 2025 at 1:26 PM
🌍Open call: Junior Group Leader positions!
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
Reposted by Michael Hoffman
After yesterday’s surrender, we’re launching the largest Democratic primary program that we’ve ever run.
We will not back any Senate primary candidate unless they call for Schumer to step down as Minority Leader.
If you’re as pissed as we are, join this campaign to rebuild the Democratic Party. 👇
We will not back any Senate primary candidate unless they call for Schumer to step down as Minority Leader.
If you’re as pissed as we are, join this campaign to rebuild the Democratic Party. 👇
Democratic leaders have failed us again. It's time to get new leaders.
After yet another capitulation by Chuck Schumer and Senate Democrats, it's clear we need new leadership capable of mounting a serious opposition to Trump's authoritarian regime. We're launching our la...
www.indivisible2026.org
November 11, 2025 at 12:00 AM
After yesterday’s surrender, we’re launching the largest Democratic primary program that we’ve ever run.
We will not back any Senate primary candidate unless they call for Schumer to step down as Minority Leader.
If you’re as pissed as we are, join this campaign to rebuild the Democratic Party. 👇
We will not back any Senate primary candidate unless they call for Schumer to step down as Minority Leader.
If you’re as pissed as we are, join this campaign to rebuild the Democratic Party. 👇
Reposted by Michael Hoffman
same. I also thanked them for voting no on the CR
I called both my senators and told staff that as a constituent I wanted to express the need for new Democratic caucus leadership in the Senate. Took two minutes.
November 11, 2025 at 12:01 AM
same. I also thanked them for voting no on the CR
I called both my senators and told staff that as a constituent I wanted to express the need for new Democratic caucus leadership in the Senate. Took two minutes.
November 10, 2025 at 11:51 PM
I called both my senators and told staff that as a constituent I wanted to express the need for new Democratic caucus leadership in the Senate. Took two minutes.
Reposted by Michael Hoffman
Dealer: alright everyone ante up
Chuck Schumer: I fold
Dealer: … we haven’t even dealt the hand yet
Chuck Schumer: I 👏 fold 👏
Chuck Schumer: I fold
Dealer: … we haven’t even dealt the hand yet
Chuck Schumer: I 👏 fold 👏
November 9, 2025 at 11:50 PM
Dealer: alright everyone ante up
Chuck Schumer: I fold
Dealer: … we haven’t even dealt the hand yet
Chuck Schumer: I 👏 fold 👏
Chuck Schumer: I fold
Dealer: … we haven’t even dealt the hand yet
Chuck Schumer: I 👏 fold 👏
The definitive obituary of James Watson, written by the late, great Sharon Begley @statnews.com www.statnews.com/2025/11/07/j...
James Watson, dead at 97, was a scientific legend and a pariah among his peers
James Watson, the co-discoverer of the structure of DNA who died Thursday at 97, was a scientific legend and a pariah among his peers.
www.statnews.com
November 10, 2025 at 5:51 PM
The definitive obituary of James Watson, written by the late, great Sharon Begley @statnews.com www.statnews.com/2025/11/07/j...
Reposted by Michael Hoffman
Concepts of a plan of a promise of a vote
November 10, 2025 at 12:37 AM
Concepts of a plan of a promise of a vote
Reposted by Michael Hoffman
Reposted by Michael Hoffman
"When I picked up my granddaughter from the federal agents, she had a dirty diaper, a bruise on her face, and was developing a rash. She was exhausted and cried… My heart aches knowing this could happen to others, to my kids, or even me, despite being U.S. citizens.”
November 8, 2025 at 3:26 PM
"When I picked up my granddaughter from the federal agents, she had a dirty diaper, a bruise on her face, and was developing a rash. She was exhausted and cried… My heart aches knowing this could happen to others, to my kids, or even me, despite being U.S. citizens.”
Reposted by Michael Hoffman
In the name of protecting Jews, Jews have their funding cancelled, get kicked out of seminars, and are removed from leadership positions in Jewish Studies to be replaced by non-Jews.
Latest write-up about outrageous administrative over reach at IU. www.jta.org/2025/11/07/u...
In Indiana, a vaunted Jewish studies program is upended by red-state politics over Israel and speech - Jewish Telegraphic Agency
A leadership shakeup, a defunded graduate student and political pressure from above have turned a storied program into a flashpoint for Trump-era campus politics.
www.jta.org
November 8, 2025 at 3:58 AM
In the name of protecting Jews, Jews have their funding cancelled, get kicked out of seminars, and are removed from leadership positions in Jewish Studies to be replaced by non-Jews.
Reposted by Michael Hoffman
No cap, imma use this just to swap yeet() for filter()
Do you teach #rstats? Do your students complain about how lame and old-fashioned dplyr is? Don't worry: I have the solution for you: github.com/hadley/genzp....
genzplyr is dplyr, but bussin fr fr no cap.
genzplyr is dplyr, but bussin fr fr no cap.
GitHub - hadley/genzplyr: dplyr but make it bussin fr fr no cap
dplyr but make it bussin fr fr no cap. Contribute to hadley/genzplyr development by creating an account on GitHub.
github.com
November 8, 2025 at 3:52 AM
No cap, imma use this just to swap yeet() for filter()
Reposted by Michael Hoffman
There are many reasons I love Los Angeles (and will visit again once the current cr*p down south fades) - this story adds to that.
www.thestar.com/sports/blue-...
www.thestar.com/sports/blue-...
‘I hope this becomes a lasting tradition.’ Dodgers fans ease Blue Jays’ World Series loss with $30,000 in donations to SickKids
Many fans donated $51 as a tribute to the Blue Jays relievers who put the number 51 on their caps to pay respects to L.A. pitcher Alex Vesia.
www.thestar.com
November 7, 2025 at 4:23 PM
There are many reasons I love Los Angeles (and will visit again once the current cr*p down south fades) - this story adds to that.
www.thestar.com/sports/blue-...
www.thestar.com/sports/blue-...
Reposted by Michael Hoffman
Me waiting for the bus omw to kick your ass
May 13, 2025 at 8:57 PM
Me waiting for the bus omw to kick your ass
Em dashes aren't the smoking gun some make them out to be, but do real humans ever use as many emoji in the middle of long text as I have been seeing in recent months?
November 7, 2025 at 1:24 AM
Em dashes aren't the smoking gun some make them out to be, but do real humans ever use as many emoji in the middle of long text as I have been seeing in recent months?
Reposted by Michael Hoffman
Ah ha ha ha ha ha ha ha ha ha ha lulz
Meanwhile in Canada: Tory MP crosses the floor to the Liberals on budget week, citing poor Tory leadership; in response, Polievre talks too much in the House and somehow gets usurped by the Bloc in opposition:
November 6, 2025 at 8:18 PM
Ah ha ha ha ha ha ha ha ha ha ha lulz
Prosecutors used to be able to get a grand jury to indict a ham sandwich.
After the damage Republicans have done to Justice's reputation, they can't even get a petit jury to convict on throwing one.
After the damage Republicans have done to Justice's reputation, they can't even get a petit jury to convict on throwing one.
Jeanine Pirro tried to make an example of Sean Dunn.
She ended up delivering a hero to Washington, D.C.
www.huffpost.com/entry/dc-san...
She ended up delivering a hero to Washington, D.C.
www.huffpost.com/entry/dc-san...
DC ‘Sandwich Guy’ Found Not Guilty After Defense Successfully Highlights Absurdity Of It All
Jeanine Pirro tried to make an example of Sean Dunn. She ended up delivering a hero to Washington, D.C.
www.huffpost.com
November 6, 2025 at 8:21 PM
Prosecutors used to be able to get a grand jury to indict a ham sandwich.
After the damage Republicans have done to Justice's reputation, they can't even get a petit jury to convict on throwing one.
After the damage Republicans have done to Justice's reputation, they can't even get a petit jury to convict on throwing one.
Reposted by Michael Hoffman
holy shit -- one of Trump's toadies just passed out and the White House event is brought to an abrupt end
November 6, 2025 at 5:38 PM
holy shit -- one of Trump's toadies just passed out and the White House event is brought to an abrupt end
Reposted by Michael Hoffman
lol
November 6, 2025 at 4:47 AM
lol
Reposted by Michael Hoffman
I can't help noticing the Supreme Court conservatives expressing the first doubt of a Trump assertion in oral arguments the day after the election day where every Republican running lost by 20 points. But they would never be swayed by such worldly things in their consideration of The Law, right?
November 6, 2025 at 3:27 AM
I can't help noticing the Supreme Court conservatives expressing the first doubt of a Trump assertion in oral arguments the day after the election day where every Republican running lost by 20 points. But they would never be swayed by such worldly things in their consideration of The Law, right?
Reposted by Michael Hoffman
When this happens in other countries, it’s the kind of thing cited as example of government brutality when arguing for regime change
Getting new details on this now:
As the arrest unfolded, teachers pleaded with the agents telling them the teacher had a work permit. The agents went into multiple rooms looking for teachers while children were present. One teacher hid with a child in her care while the agents stormed the facility.
As the arrest unfolded, teachers pleaded with the agents telling them the teacher had a work permit. The agents went into multiple rooms looking for teachers while children were present. One teacher hid with a child in her care while the agents stormed the facility.
Raids inside day cares had been off limits until this year, when, on his first day in office, President Donald Trump removed that protection.
The arrest reportedly took place in front of children.
19thnews.org/2025/11/chil...
The arrest reportedly took place in front of children.
19thnews.org/2025/11/chil...
November 5, 2025 at 10:11 PM
When this happens in other countries, it’s the kind of thing cited as example of government brutality when arguing for regime change
The advertisements for submarines here are unreal
November 5, 2025 at 10:52 PM
The advertisements for submarines here are unreal
Reposted by Michael Hoffman
The way all of these people convinced themselves that Mamdani is antisemitic is a subject far more worthy of media examination than any of the ‘groupthink on campuses!’ thinkpieces we’ve been subjected to
November 5, 2025 at 8:58 PM
The way all of these people convinced themselves that Mamdani is antisemitic is a subject far more worthy of media examination than any of the ‘groupthink on campuses!’ thinkpieces we’ve been subjected to