Jamie Cate
@jhdcate.bsky.social
Ribosomes and RNA language models.
Professor at UC Berkeley.
https://sites.google.com/berkeley.edu/cate-lab/home
Professor at UC Berkeley.
https://sites.google.com/berkeley.edu/cate-lab/home
Pinned
doi.org
"Use it or lose it." This is great advice for exercise, but when cells need to slow down or go dormant, they need to store ribosomes to recover growth in the future. They use hibernation factors to do this. Here is our latest story on how archaea hibernate ribosomes (1/7):
doi.org/10.64898/202...
doi.org/10.64898/202...
Reposted by Jamie Cate
It may actually be good for the republic to never have “the presumption of regularity” ever again.
Understand that 370 days ago even bringing a motion like this would probably have been treated as sanctionably frivolous
Today it was granted ex parte
Today it was granted ex parte
A federal judge issues a restraining order against the feds, barring them from "destroying or altering evidence"
storage.courtlistener.com/recap/gov.us...
storage.courtlistener.com/recap/gov.us...
January 25, 2026 at 5:36 AM
It may actually be good for the republic to never have “the presumption of regularity” ever again.
Reposted by Jamie Cate
Nonviolence is, in fact, working. This administration is weaker than it was a year ago. More and more of the public is becoming galvanized against it; its agents are being impeded.
Do you honestly think people in the civil rights movement and other nonviolent movements faced no violence themselves? They practiced nonviolence because it works, because the oppressor wants a shooting war, which is the war it will win
How's your non-violent working Mr Gandhi stancil? They will kill each and everyone of you right if they had the chance and you will still be writing Kumbaya.
January 24, 2026 at 9:53 PM
Nonviolence is, in fact, working. This administration is weaker than it was a year ago. More and more of the public is becoming galvanized against it; its agents are being impeded.
Reposted by Jamie Cate
LA doesn’t miss 🔥
Freeway overpass just now (405)
Freeway overpass just now (405)
January 25, 2026 at 12:03 AM
LA doesn’t miss 🔥
Freeway overpass just now (405)
Freeway overpass just now (405)
Reposted by Jamie Cate
Alex from our time working together, while he was in nursing school. Later, he moved to ICU, working as a nurse to support critically ill Veterans. He had such a great attitude. We’d chat between patients about trying to get in a mountain bike ride together. Will never happen now
January 24, 2026 at 7:39 PM
Alex from our time working together, while he was in nursing school. Later, he moved to ICU, working as a nurse to support critically ill Veterans. He had such a great attitude. We’d chat between patients about trying to get in a mountain bike ride together. Will never happen now
Reposted by Jamie Cate
Both of Arizona’s senators, @captmarkkelly.bsky.social and @gallego.senate.gov are a “no” on DHS funding.
January 25, 2026 at 1:12 AM
Both of Arizona’s senators, @captmarkkelly.bsky.social and @gallego.senate.gov are a “no” on DHS funding.
Reposted by Jamie Cate
Kare 11 local news just read, in full, this statement from Michael and Susan Pretti, the parents of Alex Pretti.
"Please get the truth out about our son."
"Please get the truth out about our son."
January 25, 2026 at 12:43 AM
Kare 11 local news just read, in full, this statement from Michael and Susan Pretti, the parents of Alex Pretti.
"Please get the truth out about our son."
"Please get the truth out about our son."
Reposted by Jamie Cate
In my ongoing attempts to give you a break from *gestures widely* THE HORRORS:
Let's talk about the utterly bizarre science of cats' purring.
Here's a weird starting point:
There are NO cats (Felidae) that can BOTH roar AND purr.
Cats that roar = genus Panthera
Cats that purr = genus Felis
Let's talk about the utterly bizarre science of cats' purring.
Here's a weird starting point:
There are NO cats (Felidae) that can BOTH roar AND purr.
Cats that roar = genus Panthera
Cats that purr = genus Felis
January 24, 2026 at 11:12 PM
In my ongoing attempts to give you a break from *gestures widely* THE HORRORS:
Let's talk about the utterly bizarre science of cats' purring.
Here's a weird starting point:
There are NO cats (Felidae) that can BOTH roar AND purr.
Cats that roar = genus Panthera
Cats that purr = genus Felis
Let's talk about the utterly bizarre science of cats' purring.
Here's a weird starting point:
There are NO cats (Felidae) that can BOTH roar AND purr.
Cats that roar = genus Panthera
Cats that purr = genus Felis
Reposted by Jamie Cate
An overhead view of protesters gathering at the scene of the shooting.
Live coverage: www.startribune.com/ice-raids-mi...
📽️ Aaron Lavinsky/The Minnesota Star Tribune
Live coverage: www.startribune.com/ice-raids-mi...
📽️ Aaron Lavinsky/The Minnesota Star Tribune
January 24, 2026 at 9:46 PM
An overhead view of protesters gathering at the scene of the shooting.
Live coverage: www.startribune.com/ice-raids-mi...
📽️ Aaron Lavinsky/The Minnesota Star Tribune
Live coverage: www.startribune.com/ice-raids-mi...
📽️ Aaron Lavinsky/The Minnesota Star Tribune
Reposted by Jamie Cate
Alex Pretti was a colleague at the VA. We hired him to recruit for our trial. He became an ICU nurse- I lover working with him. He was a good kind person who lived to help and these fuckers executed him.
White. Hot. Rage.
White. Hot. Rage.
January 24, 2026 at 7:31 PM
Alex Pretti was a colleague at the VA. We hired him to recruit for our trial. He became an ICU nurse- I lover working with him. He was a good kind person who lived to help and these fuckers executed him.
White. Hot. Rage.
White. Hot. Rage.
Reposted by Jamie Cate
I have spent my entire adult life being lectured by Republican politicians and conservative legal movement types about how important it is to preserve the sacred constitutional right to self-defense of *specifically this person* and then secret police murdered him in the street
Minneapolis police chief Brian O'Hara says that the victim was a 37-year-old white man and US citizen with no criminal record and that he was a legally permitted gun owner.
January 24, 2026 at 6:29 PM
I have spent my entire adult life being lectured by Republican politicians and conservative legal movement types about how important it is to preserve the sacred constitutional right to self-defense of *specifically this person* and then secret police murdered him in the street
Reposted by Jamie Cate
Alex Pretti, the man killed by federal agents today in Minneapolis, appears to have been a registered nurse, an athlete, a son and a brother, with ties to Colorado and Wisconsin.
Here is a photo he used for several accounts.
Here is a photo he used for several accounts.
January 24, 2026 at 7:07 PM
Alex Pretti, the man killed by federal agents today in Minneapolis, appears to have been a registered nurse, an athlete, a son and a brother, with ties to Colorado and Wisconsin.
Here is a photo he used for several accounts.
Here is a photo he used for several accounts.
Reposted by Jamie Cate
As we bear witness to what is happening in Minneapolis, remember that those who are documenting it -- citizens and journalists alike -- are showing true bravery and moral courage. This documentation will matter one day, mark my words. asharangappa.substack.com/p/the-power-...
The Power of Being Watched
Why hitting the "record" button is an act of moral courage.
asharangappa.substack.com
January 24, 2026 at 7:04 PM
As we bear witness to what is happening in Minneapolis, remember that those who are documenting it -- citizens and journalists alike -- are showing true bravery and moral courage. This documentation will matter one day, mark my words. asharangappa.substack.com/p/the-power-...
Reposted by Jamie Cate
On the execution in Minnesota: Obviously, the individuals involved should be held accountable. But responsibility goes to the top of ICE and CBP, and DHS. Their appropriations come up next week in the senate. Not a cent for DHS without pulling ICE and CBP off the streets, in MN and everywhere else.
January 24, 2026 at 4:52 PM
On the execution in Minnesota: Obviously, the individuals involved should be held accountable. But responsibility goes to the top of ICE and CBP, and DHS. Their appropriations come up next week in the senate. Not a cent for DHS without pulling ICE and CBP off the streets, in MN and everywhere else.
Reposted by Jamie Cate
Reminder: DHS legislation that funds ICE at current levels without policy restrictions is in the Senate and needs 60 votes to pass. Deadline is next Friday.
January 24, 2026 at 4:47 PM
Reminder: DHS legislation that funds ICE at current levels without policy restrictions is in the Senate and needs 60 votes to pass. Deadline is next Friday.
Reposted by Jamie Cate
ICE is now responsible for 66% of the homicides in Minneapolis this year.
January 24, 2026 at 4:51 PM
ICE is now responsible for 66% of the homicides in Minneapolis this year.
Reposted by Jamie Cate
The CDC's job is to monitor and prevent diseases. But now RFK Jr's handpicked deputy director says he "doesn't care" about whether or not measles is officially eliminated.
This is about KIDS getting sick and even DYING from something WE CAN PREVENT. Beyond despicable.
This is about KIDS getting sick and even DYING from something WE CAN PREVENT. Beyond despicable.
Measles elimination status ‘not really’ a concern, CDC official says | CNN
Ongoing measles outbreaks in multiple parts of the country are threatening the United States’ status as a nation that has eliminated the virus’ spread, but a CDC leader said Tuesday that the potential...
www.cnn.com
January 23, 2026 at 6:30 PM
The CDC's job is to monitor and prevent diseases. But now RFK Jr's handpicked deputy director says he "doesn't care" about whether or not measles is officially eliminated.
This is about KIDS getting sick and even DYING from something WE CAN PREVENT. Beyond despicable.
This is about KIDS getting sick and even DYING from something WE CAN PREVENT. Beyond despicable.
Reposted by Jamie Cate
two years old.
ICE detains 2-year-old and father, Minneapolis city council member says
The 2-year-old was reportedly detained one day after a 5-year-old was detained at school pickup.
www.kare11.com
January 24, 2026 at 12:02 AM
two years old.
Reposted by Jamie Cate
in case you're curious about how angry Minnesota is about ICE, it was -20 today
January 24, 2026 at 12:38 AM
in case you're curious about how angry Minnesota is about ICE, it was -20 today
Reposted by Jamie Cate
California just joined the World Health Organization.
I love it.
I love it.
California joins WHO public health network following US exit, marking a first for any state
California joined WHO's Global Outbreak Alert and Response Network, countering federal withdrawal from the organization.
www.abc10.com
January 23, 2026 at 10:30 PM
California just joined the World Health Organization.
I love it.
I love it.
Reposted by Jamie Cate
WHO removing Us Flag
January 23, 2026 at 9:45 PM
WHO removing Us Flag
Reposted by Jamie Cate
Reposted by Jamie Cate
At a time when ICE is rounding up 5-year-olds, terrorizing communities and killing American citizens, the last thing we should be doing is increasing its funding.
I will vote NO on the upcoming spending bill to fund Trump's domestic army.
I will vote NO on the upcoming spending bill to fund Trump's domestic army.
January 23, 2026 at 8:27 PM
At a time when ICE is rounding up 5-year-olds, terrorizing communities and killing American citizens, the last thing we should be doing is increasing its funding.
I will vote NO on the upcoming spending bill to fund Trump's domestic army.
I will vote NO on the upcoming spending bill to fund Trump's domestic army.
Reposted by Jamie Cate
Anti-ICE protesters fill the streets of downtown Minneapolis during an "ICE Out" rally on Jan. 23.
📷️ Alex Kormann/The Minnesota Star Tribune
Continuing coverage: bit.ly/3ZsrBxQ
📷️ Alex Kormann/The Minnesota Star Tribune
Continuing coverage: bit.ly/3ZsrBxQ
January 23, 2026 at 9:40 PM
Anti-ICE protesters fill the streets of downtown Minneapolis during an "ICE Out" rally on Jan. 23.
📷️ Alex Kormann/The Minnesota Star Tribune
Continuing coverage: bit.ly/3ZsrBxQ
📷️ Alex Kormann/The Minnesota Star Tribune
Continuing coverage: bit.ly/3ZsrBxQ
Reposted by Jamie Cate
Thrilled to have contributed to this work led by @jgcastillo.bsky.social during his PhD at UC Berkeley w/ Michel DuPage. Targeting FSP1 in T cells boosts anti-tumor immunity by relieving Treg suppression, revealing a new immunomodulatory therapeutic axis. www.science.org/doi/10.1126/...
Selective disruption of lipid peroxide homeostasis in intratumoral regulatory T cells by targeting FSP1 enhances cancer immunity
Deletion of Aifm2 disrupts Treg cell immunosuppression within tumors without inciting autoimmune pathology in mice.
www.science.org
January 23, 2026 at 10:12 PM
Thrilled to have contributed to this work led by @jgcastillo.bsky.social during his PhD at UC Berkeley w/ Michel DuPage. Targeting FSP1 in T cells boosts anti-tumor immunity by relieving Treg suppression, revealing a new immunomodulatory therapeutic axis. www.science.org/doi/10.1126/...
Reposted by Jamie Cate
Here is how you can help us!
This is a great article and includes a link to comprehensive list for folks who want to donate. naomikritzer.com/2026/01/21/h...
This is a great article and includes a link to comprehensive list for folks who want to donate. naomikritzer.com/2026/01/21/h...
How To Help if You are Outside Minnesota
Last edited January 22, 2026 I’m going to assume that if you’re reading this, you more or less understand the situation in Minnesota and I don’t have to explain it to you! That sa…
naomikritzer.com
January 23, 2026 at 7:36 PM
Here is how you can help us!
This is a great article and includes a link to comprehensive list for folks who want to donate. naomikritzer.com/2026/01/21/h...
This is a great article and includes a link to comprehensive list for folks who want to donate. naomikritzer.com/2026/01/21/h...