Basil Greber
@bjgreber.bsky.social
Structural biologist. High-resolution imaging of macromolecular assemblies (and landscapes). MRC career development fellow/group leader at the Institute of Cancer Research, London. Views my own.
Reposted by Basil Greber
AOC: "It's not just that Trump is corrupt. It's that everyone participating in this is corrupt — Elon is corrupt. Jeff Bezos is corrupt. Mark Zuckerberg is corrupt"
December 29, 2025 at 2:55 PM
AOC: "It's not just that Trump is corrupt. It's that everyone participating in this is corrupt — Elon is corrupt. Jeff Bezos is corrupt. Mark Zuckerberg is corrupt"
Reposted by Basil Greber
If only Americans had a recent way to know how crucial immigrants were for the success of the Manhattan Project. A big Hollywood movie where a lot of the nuclear scientist characters speak with accents and talk about fleeing Europe that makes tons of money and wins a bunch of Oscars, perhaps.
Immigrant-hating Stephen Miller talks about Americans being "first to harness the atom." But the first controlled, self-sustaining nuclear chain reaction was conducted by a team led by Italian immigrant Enrico Fermi, who didn't become a U.S. citizen until a year and a half later.
December 29, 2025 at 5:29 AM
If only Americans had a recent way to know how crucial immigrants were for the success of the Manhattan Project. A big Hollywood movie where a lot of the nuclear scientist characters speak with accents and talk about fleeing Europe that makes tons of money and wins a bunch of Oscars, perhaps.
Reposted by Basil Greber
Per NY Times’s Michael Grynbaum on X, this is Sharyn Alfonsi’s email to her “60 Minutes” colleagues in full:
December 22, 2025 at 3:37 AM
Per NY Times’s Michael Grynbaum on X, this is Sharyn Alfonsi’s email to her “60 Minutes” colleagues in full:
Reposted by Basil Greber
We have an opening for a research support officer. Come and join us! Please share.
Are you an enthusiastic and ambitious scientist looking for a challenging project?
Come and join @kellythd-nguyen.bsky.social’s group as a Research Support Officer and help decipher the molecular mechanisms of telomere maintenance!
Apply by 11 JAN
www.jobs.ac.uk/job/DPU715/r...
Come and join @kellythd-nguyen.bsky.social’s group as a Research Support Officer and help decipher the molecular mechanisms of telomere maintenance!
Apply by 11 JAN
www.jobs.ac.uk/job/DPU715/r...
December 22, 2025 at 12:09 PM
We have an opening for a research support officer. Come and join us! Please share.
Reposted by Basil Greber
it appears your manuscript "in preparation" was not published in 2025 after all, mr. bond
December 22, 2025 at 12:45 PM
it appears your manuscript "in preparation" was not published in 2025 after all, mr. bond
Reposted by Basil Greber
“These men risked their lives to speak with us. We have a moral and professional obligation to the sources who entrusted us with their
stories. Abandoning them now is a betrayal of the most basic tenet of journalism: giving voice to the voiceless.”
stories. Abandoning them now is a betrayal of the most basic tenet of journalism: giving voice to the voiceless.”
Per NY Times’s Michael Grynbaum on X, this is Sharyn Alfonsi’s email to her “60 Minutes” colleagues in full:
December 22, 2025 at 3:42 AM
“These men risked their lives to speak with us. We have a moral and professional obligation to the sources who entrusted us with their
stories. Abandoning them now is a betrayal of the most basic tenet of journalism: giving voice to the voiceless.”
stories. Abandoning them now is a betrayal of the most basic tenet of journalism: giving voice to the voiceless.”
But the next time an athlete protests racism, war, genocide, or any other atrocity, we will be reminded that “fans do not want politics to be brought into football”. FIFA is such a 💩 organisation, it beggars belief.
How Trump got his FIFA prize: Trump’s aides demanded that FIFA’s made-up “peace prize” awarded to him be literally as big as the World Cup. The White House gave FIFA a list of demands regarding the inaugural FIFA Peace Prize, which was invented by FIFA president Gianni Infantino to present to Trump.
White House Made Bizarre Demands for Trump’s Bogus Peace Prize
A report has outlined how the White House dictated FIFA’s Peace Prize ceremony to Donald Trump.
www.thedailybeast.com
December 20, 2025 at 3:21 PM
But the next time an athlete protests racism, war, genocide, or any other atrocity, we will be reminded that “fans do not want politics to be brought into football”. FIFA is such a 💩 organisation, it beggars belief.
Reposted by Basil Greber
If we treated him like a normal president he’d be in prison right now
December 20, 2025 at 3:30 AM
If we treated him like a normal president he’d be in prison right now
Reposted by Basil Greber
Closing out my year with a journal editor shocker 🧵
Checking new manuscripts today I reviewed a paper attributing 2 papers to me I did not write. A daft thing for an author to do of course. But intrigued I web searched up one of the titles and that's when it got real weird...
Checking new manuscripts today I reviewed a paper attributing 2 papers to me I did not write. A daft thing for an author to do of course. But intrigued I web searched up one of the titles and that's when it got real weird...
December 19, 2025 at 5:20 PM
Closing out my year with a journal editor shocker 🧵
Checking new manuscripts today I reviewed a paper attributing 2 papers to me I did not write. A daft thing for an author to do of course. But intrigued I web searched up one of the titles and that's when it got real weird...
Checking new manuscripts today I reviewed a paper attributing 2 papers to me I did not write. A daft thing for an author to do of course. But intrigued I web searched up one of the titles and that's when it got real weird...
Reposted by Basil Greber
HAPPY HOLIDAYS TO ALL OF YOU!🎄✨
December 19, 2025 at 6:08 PM
HAPPY HOLIDAYS TO ALL OF YOU!🎄✨
Reposted by Basil Greber
For the last few months, I've been working on a story about January's crash near Washington, D.C. What I learned was that it was simply an accident waiting to happen.
Special Report: The night everything at DCA finally went wrong (via @theaircurrent.com) theaircurrent.com/aviation-saf...
Special Report: The night everything at DCA finally went wrong (via @theaircurrent.com) theaircurrent.com/aviation-saf...
Special Report: The night everything at DCA finally went wrong
D.C. midair crash was the result of a complete collapse of the protections designed to keep aviation safe — and the institutions that design and maintain them
theaircurrent.com
December 18, 2025 at 6:26 PM
For the last few months, I've been working on a story about January's crash near Washington, D.C. What I learned was that it was simply an accident waiting to happen.
Special Report: The night everything at DCA finally went wrong (via @theaircurrent.com) theaircurrent.com/aviation-saf...
Special Report: The night everything at DCA finally went wrong (via @theaircurrent.com) theaircurrent.com/aviation-saf...
👀
Molecular basis of XPF-ERCC1 targeting to SLX4-dependent DNA repair pathways pubmed.ncbi.nlm.nih.gov/41402316/ #cryoem
December 17, 2025 at 5:50 PM
👀
Reposted by Basil Greber
An early Christmas present! The ICR’s new Hydra Bio FIB-SEM has been delivered, which will sit at the heart of a consortium between the @icr.ac.uk, Imperial, QMUL and KCL. Currently being stored at Imperial, it’ll be installed in a brand new lab at the ICR next year. Exciting things coming in 2026!🔬
December 17, 2025 at 12:58 PM
An early Christmas present! The ICR’s new Hydra Bio FIB-SEM has been delivered, which will sit at the heart of a consortium between the @icr.ac.uk, Imperial, QMUL and KCL. Currently being stored at Imperial, it’ll be installed in a brand new lab at the ICR next year. Exciting things coming in 2026!🔬
Reposted by Basil Greber
Before the 1990s, plane crashes caused by microbursts used to kill planeloads of people fairly regularly.
Dr. Ted Fujita and NCAR scientists figured out how to detect microbursts and warn pilots about them.
Since then? Zero airliner crashes from microbursts.
Dr. Ted Fujita and NCAR scientists figured out how to detect microbursts and warn pilots about them.
Since then? Zero airliner crashes from microbursts.
Exclusive: The Trump administration is moving to dismantle the National Center for Atmospheric Research in Colorado, according to a senior White House official, taking aim at one of the world's leading climate research labs.
Trump moves to dismantle major US climate research center in Colorado
The Trump administration is breaking up the National Center for Atmospheric Research, taking aim at one of the world's leading climate research labs.
bit.ly
December 17, 2025 at 3:47 AM
Before the 1990s, plane crashes caused by microbursts used to kill planeloads of people fairly regularly.
Dr. Ted Fujita and NCAR scientists figured out how to detect microbursts and warn pilots about them.
Since then? Zero airliner crashes from microbursts.
Dr. Ted Fujita and NCAR scientists figured out how to detect microbursts and warn pilots about them.
Since then? Zero airliner crashes from microbursts.
Reposted by Basil Greber
Our latest paper on the molecular mechanisms of XPF-ERCC1 recruitment to SLX4-dependent DNA repair pathways has been published! Congratulations to first author Junjie Feng, and a heartfelt thank you to all our collaborators for their contributions to this study!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
December 16, 2025 at 4:29 PM
Our latest paper on the molecular mechanisms of XPF-ERCC1 recruitment to SLX4-dependent DNA repair pathways has been published! Congratulations to first author Junjie Feng, and a heartfelt thank you to all our collaborators for their contributions to this study!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Our latest paper on the molecular mechanisms of XPF-ERCC1 recruitment to SLX4-dependent DNA repair pathways has been published! Congratulations to first author Junjie Feng, and a heartfelt thank you to all our collaborators for their contributions to this study!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
December 16, 2025 at 4:29 PM
Our latest paper on the molecular mechanisms of XPF-ERCC1 recruitment to SLX4-dependent DNA repair pathways has been published! Congratulations to first author Junjie Feng, and a heartfelt thank you to all our collaborators for their contributions to this study!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Vault shell turducken. 👀
Vaults. They are cell biology's greatest puzzle! This preprint from Martin Beck's lab shows them docked on ER membranes with a ribosome inside. What on earth is going on there??
#CellBiology #WTFology
www.biorxiv.org/content/10.6...
#CellBiology #WTFology
www.biorxiv.org/content/10.6...
The vault associates with membranes in situ
The eukaryotic vault particle is a giant ribonucleoprotein complex that assembles into an iconic barrel-like cage. Its cellular function has remained elusive despite extensive characterization. Using ...
www.biorxiv.org
December 16, 2025 at 10:07 AM
Vault shell turducken. 👀
Reposted by Basil Greber
Reposted by Basil Greber
Here is why friends don't let friends calculate FSC on denoised half-maps. I took EMD-17961, denoised the maps using Warp's Noise2Map, and calculated the FSC between various things. With noise gone from the half-maps, their consistency is no longer related to SSNR. Denoised map vs. model still works
December 15, 2025 at 1:53 AM
Here is why friends don't let friends calculate FSC on denoised half-maps. I took EMD-17961, denoised the maps using Warp's Noise2Map, and calculated the FSC between various things. With noise gone from the half-maps, their consistency is no longer related to SSNR. Denoised map vs. model still works
Reposted by Basil Greber
King Charles argued on Friday that, thanks to early diagnosis, his treatment will be reduced in the New Year.
He urged people to take up cancer screening saying: “Early diagnosis quite simply saves lives.”
www.bbc.co.uk/news/a...
1/10
He urged people to take up cancer screening saying: “Early diagnosis quite simply saves lives.”
www.bbc.co.uk/news/a...
1/10
King Charles 'deeply touched' by reaction to cancer TV message, says Buckingham Palace
In a TV broadcast on Friday night, the King said an early diagnosis was key to the "good news" that his treatment is being scaled back.
www.bbc.co.uk
December 14, 2025 at 8:02 AM
King Charles argued on Friday that, thanks to early diagnosis, his treatment will be reduced in the New Year.
He urged people to take up cancer screening saying: “Early diagnosis quite simply saves lives.”
www.bbc.co.uk/news/a...
1/10
He urged people to take up cancer screening saying: “Early diagnosis quite simply saves lives.”
www.bbc.co.uk/news/a...
1/10
Reposted by Basil Greber
It would be a great start if the individual methods papers could quantify the quality of their own results instead of relying on visual vibes
December 13, 2025 at 5:15 PM
It would be a great start if the individual methods papers could quantify the quality of their own results instead of relying on visual vibes
Reposted by Basil Greber
Great to see Samuraciclib still doing well and importantly showing benefits to cancer patients www.imperial.ac.uk/news/article...
Imperial drug candidate for treatment-resistant breast cancer delivers positive results in Phase 2 trial
A drug candidate discovered at Imperial has shown promise for treating breast cancers that have stopped responding to other therapies in a Phase 2 tr...
www.imperial.ac.uk
December 12, 2025 at 2:52 PM
Great to see Samuraciclib still doing well and importantly showing benefits to cancer patients www.imperial.ac.uk/news/article...
This is sensationalist. Very well done on defusing that incident, but the plane would have kept flying. In 2023, someone managed to open a door on an Asiana Airlines flight at 650 ft altitude; in another case a door plug blew out of an Alaska Airlines 737 MAX. The planes landed safely in both cases.
Experience: I stopped a man from crashing our plane
Experience: I stopped a man from crashing our plane
A passenger having a mental health episode was heading for the emergency exit. He lunged for the door handle, screaming
www.theguardian.com
December 12, 2025 at 10:59 AM
This is sensationalist. Very well done on defusing that incident, but the plane would have kept flying. In 2023, someone managed to open a door on an Asiana Airlines flight at 650 ft altitude; in another case a door plug blew out of an Alaska Airlines 737 MAX. The planes landed safely in both cases.
Reposted by Basil Greber
