Karolin Luger
@nucleosomepolice.bsky.social
Chromatin and cryoEM afficionada. Still a fan of crystallography. Avid Colorado hiker. Will call out ugly nucleosome cartoons. Come for the science, stay for the mountain pictures and snark. Opinions and snark are my own.
Pinned
Histone PARylation factor 1: a review of its role in the DNA damage response
Abstract. Although poly-(ADP ribose) polymerase 1 (PARP1) and PARylation of histones have been known for over 50 years and have been successfully targeted
academic.oup.com
Beautiful review from J. Rudolph on Histone PARylation factor 1: a review of its role in the DNA damage response url: academic.oup.com/nar/article/...
Reposted by Karolin Luger
North of the Arctic Circle it’s winter wonderland already
November 17, 2025 at 7:42 PM
North of the Arctic Circle it’s winter wonderland already
Reposted by Karolin Luger
🔬 Experience Research Life at Cambridge!
Applications are now open for the 2026 Experience Postgrad Life Sciences Programme. Gain hands-on lab experience with an 8-week summer placement, in partnership with @corpuscambridge.bsky.social!
🔗 www.exppg.lifesci.cam.ac.uk
#SummerPlacement #Cambridge
Applications are now open for the 2026 Experience Postgrad Life Sciences Programme. Gain hands-on lab experience with an 8-week summer placement, in partnership with @corpuscambridge.bsky.social!
🔗 www.exppg.lifesci.cam.ac.uk
#SummerPlacement #Cambridge
November 13, 2025 at 10:52 AM
🔬 Experience Research Life at Cambridge!
Applications are now open for the 2026 Experience Postgrad Life Sciences Programme. Gain hands-on lab experience with an 8-week summer placement, in partnership with @corpuscambridge.bsky.social!
🔗 www.exppg.lifesci.cam.ac.uk
#SummerPlacement #Cambridge
Applications are now open for the 2026 Experience Postgrad Life Sciences Programme. Gain hands-on lab experience with an 8-week summer placement, in partnership with @corpuscambridge.bsky.social!
🔗 www.exppg.lifesci.cam.ac.uk
#SummerPlacement #Cambridge
you couldnt make this S*&%t up.
I really underestimated the depravity of the American junkers
When former Harvard President Lawrence H. Summers was pursuing a romantic relationship with a woman he described as a mentee, he turned to a longtime associate for guidance: Jeffrey E. Epstein.
Dhruv T. Patel and Cam N. Srivastava report.
Dhruv T. Patel and Cam N. Srivastava report.
November 17, 2025 at 6:48 PM
you couldnt make this S*&%t up.
Reposted by Karolin Luger
Ten days left to apply to be a @crick.ac.uk Early Career Group Leader
Closing date 27th November
www.crick.ac.uk/careers-stud...
Closing date 27th November
www.crick.ac.uk/careers-stud...
November 17, 2025 at 11:55 AM
Ten days left to apply to be a @crick.ac.uk Early Career Group Leader
Closing date 27th November
www.crick.ac.uk/careers-stud...
Closing date 27th November
www.crick.ac.uk/careers-stud...
Reposted by Karolin Luger
I E M B E R S O F T H E F R O Z E N
D A W N I
A winter world in motion — where light fractures, shadows race, and the dawn feels alive beneath your feet. The piece bursts with color, chaos, and the electricity of a sun fighting through the cold.
—The Asylum Art—
Art and words by Yves
D A W N I
A winter world in motion — where light fractures, shadows race, and the dawn feels alive beneath your feet. The piece bursts with color, chaos, and the electricity of a sun fighting through the cold.
—The Asylum Art—
Art and words by Yves
November 16, 2025 at 12:14 PM
I E M B E R S O F T H E F R O Z E N
D A W N I
A winter world in motion — where light fractures, shadows race, and the dawn feels alive beneath your feet. The piece bursts with color, chaos, and the electricity of a sun fighting through the cold.
—The Asylum Art—
Art and words by Yves
D A W N I
A winter world in motion — where light fractures, shadows race, and the dawn feels alive beneath your feet. The piece bursts with color, chaos, and the electricity of a sun fighting through the cold.
—The Asylum Art—
Art and words by Yves
Reposted by Karolin Luger
A tour de force expose of those trying to smother us in anti-science propaganda. Michael Mann and Peter Hotez are leaders in confronting the anti-science crowd. They describe their own experiences and name and shame the organizations and individuals involved and how we can defeat them. Read it. 🧪
November 13, 2025 at 10:52 PM
A tour de force expose of those trying to smother us in anti-science propaganda. Michael Mann and Peter Hotez are leaders in confronting the anti-science crowd. They describe their own experiences and name and shame the organizations and individuals involved and how we can defeat them. Read it. 🧪
Reposted by Karolin Luger
My quote of the day
In a world where everyone is behaving honestly, any dishonesty constitutes a big infraction. But, in a world where many people are behaving dishonestly, and the news is filled with stories of their infractions, even big infractions can feel small to the perpetrator.
Dan Ariely
In a world where everyone is behaving honestly, any dishonesty constitutes a big infraction. But, in a world where many people are behaving dishonestly, and the news is filled with stories of their infractions, even big infractions can feel small to the perpetrator.
Dan Ariely
November 16, 2025 at 1:32 PM
My quote of the day
In a world where everyone is behaving honestly, any dishonesty constitutes a big infraction. But, in a world where many people are behaving dishonestly, and the news is filled with stories of their infractions, even big infractions can feel small to the perpetrator.
Dan Ariely
In a world where everyone is behaving honestly, any dishonesty constitutes a big infraction. But, in a world where many people are behaving dishonestly, and the news is filled with stories of their infractions, even big infractions can feel small to the perpetrator.
Dan Ariely
Reposted by Karolin Luger
in like a month, they're going to advocate for chewing on raw willow bark instead.
JD Vance calls ibuprofen "useless medication" and implies it's not "necessary, safe and effective."
November 13, 2025 at 4:00 PM
in like a month, they're going to advocate for chewing on raw willow bark instead.
Reposted by Karolin Luger
I am begging of grad admissions software to not require accounts and resetting passwords and just send a single link we can use to upload letters. On years when I write dozens of letters, I waste hours dealing with clunky interfaces.
November 13, 2025 at 5:19 PM
I am begging of grad admissions software to not require accounts and resetting passwords and just send a single link we can use to upload letters. On years when I write dozens of letters, I waste hours dealing with clunky interfaces.
Reposted by Karolin Luger
Biological Chemistry's position is still taking applications. UM is a great place to be a PI, I'd love to see a new membrane biology or lipids expert join our community.
This is open for new and established investigators.
This is open for new and established investigators.
Collaborative. Creative. Impactful. Come join us in Ann Arbor! For more information and application link see jobs.sciencecareers.org/job/675674/f...
November 11, 2025 at 3:33 PM
Biological Chemistry's position is still taking applications. UM is a great place to be a PI, I'd love to see a new membrane biology or lipids expert join our community.
This is open for new and established investigators.
This is open for new and established investigators.
#dontlookup nothing to see here
The big question is if the red-marked part of the graph is the beginning of another step shape, like the green and yellow before it… or whether we’ve entered a new phase of runaway feedback loops…
November 11, 2025 at 3:19 PM
#dontlookup nothing to see here
totally normal stuff. #dontlookup
"As a scientist, I've never had reason to be so concerned as I am today for the future we are facing," states PIK Director Johan Rockström as #COP30 kicks off in Belém, Brazil. The first ever Planetary Science Pavilion, under the mandate from COP30 Brazil, and together with Carlos A. Nobre,... 1/2
Raising the Voice of Science: COP30’s New Planetary Science Pavilion in Belém
YouTube video by Potsdam Institute for Climate Impact Research PIK
www.youtube.com
November 11, 2025 at 3:19 PM
totally normal stuff. #dontlookup
Beautiful review from J. Rudolph on Histone PARylation factor 1: a review of its role in the DNA damage response url: academic.oup.com/nar/article/...
Histone PARylation factor 1: a review of its role in the DNA damage response
Abstract. Although poly-(ADP ribose) polymerase 1 (PARP1) and PARylation of histones have been known for over 50 years and have been successfully targeted
academic.oup.com
November 11, 2025 at 2:49 PM
Beautiful review from J. Rudolph on Histone PARylation factor 1: a review of its role in the DNA damage response url: academic.oup.com/nar/article/...
2000 pieces . Took a hot minute. But fun
November 11, 2025 at 3:08 AM
2000 pieces . Took a hot minute. But fun
Reposted by Karolin Luger
🌍Open call: Junior Group Leader positions!
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
November 10, 2025 at 1:26 PM
🌍Open call: Junior Group Leader positions!
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
Been a bit more precise with my piecing so blocks came together without the usual stretching and cussing
November 10, 2025 at 12:51 AM
Been a bit more precise with my piecing so blocks came together without the usual stretching and cussing
another sunday, another slew of reco letters for my lovely undergrads. ~ 12 students, each applying to 10-15 schools. you do the math. Why on earth no centralized system like for med school? You do the math for how many faculty hours are 'lost' each fall to this mindless (yet important!) task.
November 9, 2025 at 2:23 PM
another sunday, another slew of reco letters for my lovely undergrads. ~ 12 students, each applying to 10-15 schools. you do the math. Why on earth no centralized system like for med school? You do the math for how many faculty hours are 'lost' each fall to this mindless (yet important!) task.
Reposted by Karolin Luger
Just worth reminding everybody whenever Photo 51 is shown that the mathematical theory that allowed the diffraction pattern to be analysed was developed in two papers by Frances Crick.
November 9, 2025 at 9:34 AM
Just worth reminding everybody whenever Photo 51 is shown that the mathematical theory that allowed the diffraction pattern to be analysed was developed in two papers by Frances Crick.
Reposted by Karolin Luger
Bluetorial-Jim Watson
I met Jim Watson a few times but did not know him well. However, I was greatly influenced by his book “The Double Helix”. He was a complicated human being with some very, very bad features, but some good contributions.
What follows is my personal perspective.
1/41
I met Jim Watson a few times but did not know him well. However, I was greatly influenced by his book “The Double Helix”. He was a complicated human being with some very, very bad features, but some good contributions.
What follows is my personal perspective.
1/41
a cartoon says hey everybody an old man 's talking while bart simpson looks on
ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on
media.tenor.com
November 8, 2025 at 1:58 PM
Bluetorial-Jim Watson
I met Jim Watson a few times but did not know him well. However, I was greatly influenced by his book “The Double Helix”. He was a complicated human being with some very, very bad features, but some good contributions.
What follows is my personal perspective.
1/41
I met Jim Watson a few times but did not know him well. However, I was greatly influenced by his book “The Double Helix”. He was a complicated human being with some very, very bad features, but some good contributions.
What follows is my personal perspective.
1/41
@nucleosomepolice 😍 this image by RF, but thinks there are missed opportunities here. 'And in order to squeeze that six feet of DNA into a single cell, it has to be coiled up in exquisitely complex tangles that change shape from one second to the next.' dang right! www.nytimes.com/2025/11/07/s...
The DNA Helix Changed How We Thought About Ourselves
www.nytimes.com
November 8, 2025 at 2:22 PM
@nucleosomepolice 😍 this image by RF, but thinks there are missed opportunities here. 'And in order to squeeze that six feet of DNA into a single cell, it has to be coiled up in exquisitely complex tangles that change shape from one second to the next.' dang right! www.nytimes.com/2025/11/07/s...
Reposted by Karolin Luger
Her sister wrote my favorite essay about her. She points out that RF would have been famous even if she'd never looked at DNA
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
Remembering my sister Rosalind Franklin
Rosalind Franklin died of ovarian cancer in 1958 aged 37 years. Sympathy and feminism
have combined to give us her familiar image as a downtrodden woman scientist, brilliant
but neglected, a heroine t...
www.thelancet.com
November 7, 2025 at 11:20 PM
Her sister wrote my favorite essay about her. She points out that RF would have been famous even if she'd never looked at DNA
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
mixed feels. www.nytimes.com/2025/11/07/s...
James Watson, Co-Discoverer of the Structure of DNA, Is Dead at 97
www.nytimes.com
November 7, 2025 at 9:29 PM
mixed feels. www.nytimes.com/2025/11/07/s...