Carolyn Bertozzi
@carolynbertozzi.bskyverified.social
All views and opinions expressed are my own.
Reposted by Carolyn Bertozzi
Material Scientists, inc Prof. Fang Liu, developed a room-temperature nanoscale quantum device using molybdenum diselenide to create “twisted light” and stable quantum states - a major step toward practical, miniaturized quantum tech.
Learn more: chemistry.stanford.edu/news/scienti...
Learn more: chemistry.stanford.edu/news/scienti...
Scientists achieve breakthrough on quantum signaling | Chemistry
Present-day quantum computers are big, expensive, and impractical, operating at temperatures near -459 degrees Fahrenheit, or “absolute zero.” In a new paper, however, materials scientists at Stanford...
chemistry.stanford.edu
December 18, 2025 at 7:58 PM
Material Scientists, inc Prof. Fang Liu, developed a room-temperature nanoscale quantum device using molybdenum diselenide to create “twisted light” and stable quantum states - a major step toward practical, miniaturized quantum tech.
Learn more: chemistry.stanford.edu/news/scienti...
Learn more: chemistry.stanford.edu/news/scienti...
Reposted by Carolyn Bertozzi
First year grad students and postdocs! Get a free starter pack from New England Biolabs!
www.neb.com/en-us/promot...
www.neb.com/en-us/promot...
New Student Starter Pack | NEB
Request your new student starter pack from NEB. It’s full of helpful resources, supplies for your lab, and some NEB swag!
www.neb.com
December 18, 2025 at 9:07 PM
First year grad students and postdocs! Get a free starter pack from New England Biolabs!
www.neb.com/en-us/promot...
www.neb.com/en-us/promot...
Reposted by Carolyn Bertozzi
We’re highlighting some of the many impactful contributions from the Sarafan ChEM-H community this year. Read the thread below for our #YearInReview!
December 18, 2025 at 1:04 AM
We’re highlighting some of the many impactful contributions from the Sarafan ChEM-H community this year. Read the thread below for our #YearInReview!
Learning a lot about bioorthogonal chemistry and clinical translation, great symposium organized by @pengwu.bsky.social and @siglecdude.bsky.social !
“Hawaii doesn’t feel like anywhere else. It is so welcoming to everyone.”
Thank you @carolynbertozzi.bskyverified.social l for joining us at #Pacifichem2025! Don’t miss her presentation this afternoon that is part of the Bio-Orthogonal Chemistry and Click Chemistry session.
Thank you @carolynbertozzi.bskyverified.social l for joining us at #Pacifichem2025! Don’t miss her presentation this afternoon that is part of the Bio-Orthogonal Chemistry and Click Chemistry session.
December 18, 2025 at 2:06 AM
Learning a lot about bioorthogonal chemistry and clinical translation, great symposium organized by @pengwu.bsky.social and @siglecdude.bsky.social !
They posted these director level positions online with a two week deadline. These are high level positions that are typically filled through an intensive search process: canvassing and outreach, community vetting, top scientists with leadership experience. This kind of talent is not fungible.
We are learning firsthand how easy it is to destroy things. It will take decades to rebuild what we have lost.
www.reuters.com/business/hea...
www.reuters.com/business/hea...
US NIH races to fill nearly half its top roles after wave of departures
The U.S. National Institutes of Health is seeking to fill nearly half of its top roles at breakneck speed following a wave of departures since President Donald Trump's return to office in January, acc...
www.reuters.com
December 17, 2025 at 4:32 PM
They posted these director level positions online with a two week deadline. These are high level positions that are typically filled through an intensive search process: canvassing and outreach, community vetting, top scientists with leadership experience. This kind of talent is not fungible.
Reposted by Carolyn Bertozzi
My friend @alexchesler.bsky.social has left the NIH to become VP of Pain Research at Vertex. I am glad to welcome him to San Diego. Exciting for him and for Vertex. But NIH loses one of its superstars. Can’t help but wonder whether this government’s anti-science policies made that decision easier.
Some news. Exciting new challenges and opportunities ahead.
December 17, 2025 at 4:20 AM
My friend @alexchesler.bsky.social has left the NIH to become VP of Pain Research at Vertex. I am glad to welcome him to San Diego. Exciting for him and for Vertex. But NIH loses one of its superstars. Can’t help but wonder whether this government’s anti-science policies made that decision easier.
Mind blowing new preprint and Bluetorial by @krishnanyamuna.bsky.social! Shows how much we have yet to learn about cellular chemistry, the curtains get pulled back more and more with each new technology her lab invents! 👏 👏
Organelles do NOT have a single uniform pH.
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
Organelles harbour pH gradients https://www.biorxiv.org/content/10.64898/2025.12.12.694065v1
December 17, 2025 at 3:38 AM
Mind blowing new preprint and Bluetorial by @krishnanyamuna.bsky.social! Shows how much we have yet to learn about cellular chemistry, the curtains get pulled back more and more with each new technology her lab invents! 👏 👏
Exciting new work from @beattylab.bsky.social and team, congratulations 👏
New work from my team, identifying drug targets in M. abscessus. Pre-print posted here:
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Chemoproteomic elucidation of β-lactam drug targets in Mycobacterium abscessus
The pathogen Mycobacterium abscessus ( Mab ) can cause severe and difficult to treat chronic lung infections. Despite the rising incidence and clinical concern of Mab infections, treatment options are...
www.biorxiv.org
December 17, 2025 at 3:33 AM
Exciting new work from @beattylab.bsky.social and team, congratulations 👏
Nice piece on @jcstark.bsky.social’s work on antibody-lectin chimeras (AbLecs), a new type of bispecific for cancer immune therapy and more #glycotime
news.mit.edu/2025/new-imm...
news.mit.edu/2025/new-imm...
A new immunotherapy approach could work for many types of cancer
Using molecules called AbLecs that block an immune checkpoint, researchers showed they could stimulate a strong anti-tumor immune response. The approach, which could work for many types of cancer, was...
news.mit.edu
December 16, 2025 at 11:51 PM
Nice piece on @jcstark.bsky.social’s work on antibody-lectin chimeras (AbLecs), a new type of bispecific for cancer immune therapy and more #glycotime
news.mit.edu/2025/new-imm...
news.mit.edu/2025/new-imm...
Reposted by Carolyn Bertozzi
The 2026 Chemical Engineering Faculty Jobs List (run by Arvind Ganesan and Todd N. Whittaker) has 92 research/teaching positions and 19 teaching-only positions: docs.google.com/spreadsheets... #facultychemEjobs
AY25-26 Chemical Engineering Faculty Jobs List
docs.google.com
December 16, 2025 at 6:04 PM
The 2026 Chemical Engineering Faculty Jobs List (run by Arvind Ganesan and Todd N. Whittaker) has 92 research/teaching positions and 19 teaching-only positions: docs.google.com/spreadsheets... #facultychemEjobs
Congratulations @jcstark.bsky.social and the team, antibody-lectin chimeras (AbLecs), a new modality for cancer immune therapy, now published @natbiotech.nature.com. These bispecifics can block glyco-immune checkpoint receptor ligands directly at the immune synapse/activate immune effector functions
Antibody-lectin chimeras for glyco-immune checkpoint blockade - @jcstark.bsky.social @carolynbertozzi.bskyverified.social go.nature.com/4aRDpk8
Antibody-lectin chimeras for glyco-immune checkpoint blockade - Nature Biotechnology
Cancer immunotherapy benefits from antibody-lectin chimeras that block glyco-immune checkpoints.
go.nature.com
December 16, 2025 at 4:55 PM
Congratulations @jcstark.bsky.social and the team, antibody-lectin chimeras (AbLecs), a new modality for cancer immune therapy, now published @natbiotech.nature.com. These bispecifics can block glyco-immune checkpoint receptor ligands directly at the immune synapse/activate immune effector functions
Reposted by Carolyn Bertozzi
If you are at #Pacifichem2025 I'll be opening the symposium of Advances in Glycan Structure and Dynamics [BIO004] at 9:15 am (sadly) from Southampton (UK) and not from Honolulu 😔, but I'll try to keep the #glycotime lively and cheerful even from afar 🤩👍
December 15, 2025 at 5:47 PM
If you are at #Pacifichem2025 I'll be opening the symposium of Advances in Glycan Structure and Dynamics [BIO004] at 9:15 am (sadly) from Southampton (UK) and not from Honolulu 😔, but I'll try to keep the #glycotime lively and cheerful even from afar 🤩👍
Linking the glycome and transcriptome at the single cell level #glycotime
Online now! Online now! Single-cell glycome and transcriptome profiling enabled by a library of anti-glycan antibodies #chembiol
Single-cell glycome and transcriptome profiling enabled by a library of anti-glycan antibodies
Marglous et al. generated a database of anti-glycan antibody sequences, expressed and characterized a library of 154 antibodies, and generated DNA-barcoded antibodies for single-cell transcriptome and glycome profiling. Glycans associated with cancer stem cells and metastasis were uncovered, demonstrating utility for basic and clinical research.
dlvr.it
December 15, 2025 at 4:54 PM
Linking the glycome and transcriptome at the single cell level #glycotime
Reposted by Carolyn Bertozzi
Online now! Online now! Single-cell glycome and transcriptome profiling enabled by a library of anti-glycan antibodies #chembiol
Single-cell glycome and transcriptome profiling enabled by a library of anti-glycan antibodies
Marglous et al. generated a database of anti-glycan antibody sequences, expressed and characterized a library of 154 antibodies, and generated DNA-barcoded antibodies for single-cell transcriptome and glycome profiling. Glycans associated with cancer stem cells and metastasis were uncovered, demonstrating utility for basic and clinical research.
dlvr.it
December 15, 2025 at 4:30 PM
Online now! Online now! Single-cell glycome and transcriptome profiling enabled by a library of anti-glycan antibodies #chembiol
Reposted by Carolyn Bertozzi
We are hiring a lab manager, for our research group, the Synthetic Neurobiology group (aka Boyden Lab) at MIT/HHMI (on the MIT campus, Cambridge, MA)! Please apply if you're qualified and interested, and spread the word! hhmi.wd1.myworkdayjobs.com/External/job...
Laboratory Manager II - Boyden Lab
Primary Work Address: 77 Massachusetts Avenue, Cambridge, MA, 02139 Current HHMI Employees, click here to apply via your Workday account. The Synthetic Neurobiology Group (Boyden Lab) at the MIT McGov...
hhmi.wd1.myworkdayjobs.com
December 12, 2025 at 3:11 PM
We are hiring a lab manager, for our research group, the Synthetic Neurobiology group (aka Boyden Lab) at MIT/HHMI (on the MIT campus, Cambridge, MA)! Please apply if you're qualified and interested, and spread the word! hhmi.wd1.myworkdayjobs.com/External/job...
Nice piece on recent article by Seyedsayamdost lab @princeton.edu published at ACS Cent. Sci.
News:
www.acs.org/pressroom/pr...
Article:
pubs.acs.org/doi/10.1021/...
News:
www.acs.org/pressroom/pr...
Article:
pubs.acs.org/doi/10.1021/...
www.acs.org
December 12, 2025 at 5:19 PM
Nice piece on recent article by Seyedsayamdost lab @princeton.edu published at ACS Cent. Sci.
News:
www.acs.org/pressroom/pr...
Article:
pubs.acs.org/doi/10.1021/...
News:
www.acs.org/pressroom/pr...
Article:
pubs.acs.org/doi/10.1021/...
Congratulations Jason Lewis!
🎉 Congratulations to MSK's Dr. Jason Lewis for being elected as a Fellow of the National Academy of Inventors, a prestigious honor recognizing individuals who have demonstrated innovation and made tangible contributions to the advancement of technology. Learn more: www.mskcc.org/news-release...
December 11, 2025 at 9:21 PM
Congratulations Jason Lewis!
Reposted by Carolyn Bertozzi
I’m so speechless at this meaningless cruelty and disrespect for the best of our citizens who often had to QUIT TENURED JOBS to serve our country instead. Way to make us great again I guess 🤬
NSF
- Forced reorg
- POs down ~ 40% (DRP, most rotators not renewed, retirements)
- Forced move (and we have to pack and clean) to a building with no furniture, little to no conference space for panels, inadequate 🛜, …)
I personally love the boxes they gave us for packing.
“Details matter” 🙃
- Forced reorg
- POs down ~ 40% (DRP, most rotators not renewed, retirements)
- Forced move (and we have to pack and clean) to a building with no furniture, little to no conference space for panels, inadequate 🛜, …)
I personally love the boxes they gave us for packing.
“Details matter” 🙃
December 11, 2025 at 3:10 PM
I’m so speechless at this meaningless cruelty and disrespect for the best of our citizens who often had to QUIT TENURED JOBS to serve our country instead. Way to make us great again I guess 🤬
I love this thread by @glycoshape.org, this is @bsky.app at its best!
Super interesting work from @carolynbertozzi.bskyverified.social group about the effects of glycosylation in protein structure and function at the proteome scale 🤯💥🤩
Results show that sialylation and fucosylation are crucial, which makes a lot of sense. We did some extra bits 🧐 with GlycoShape ⬇️🧵
Results show that sialylation and fucosylation are crucial, which makes a lot of sense. We did some extra bits 🧐 with GlycoShape ⬇️🧵
Congratulations former postdoc @jfhevler.bsky.social (in transit to Roche) and the team on their work using thermal proteome profiling along with glycosylation perturbagens to discover glycan-dependent protein functions at the proteome scale 👏
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
December 11, 2025 at 4:25 PM
I love this thread by @glycoshape.org, this is @bsky.app at its best!
Reposted by Carolyn Bertozzi
It's happening! Canada launched two programs to recruit international researchers.
Canada Impact+ Research Chairs (1 million/yr for 8 yrs +)
Canada Impact+ Emerging Leaders.
I will do my best to facilitate the process for those interested. Hit me up.
www.canada.ca/en/impact-pl...
Canada Impact+ Research Chairs (1 million/yr for 8 yrs +)
Canada Impact+ Emerging Leaders.
I will do my best to facilitate the process for those interested. Hit me up.
www.canada.ca/en/impact-pl...
The Government of Canada introduces new programs for international researchers - Canada.ca
www.canada.ca
December 9, 2025 at 6:06 PM
It's happening! Canada launched two programs to recruit international researchers.
Canada Impact+ Research Chairs (1 million/yr for 8 yrs +)
Canada Impact+ Emerging Leaders.
I will do my best to facilitate the process for those interested. Hit me up.
www.canada.ca/en/impact-pl...
Canada Impact+ Research Chairs (1 million/yr for 8 yrs +)
Canada Impact+ Emerging Leaders.
I will do my best to facilitate the process for those interested. Hit me up.
www.canada.ca/en/impact-pl...
Reposted by Carolyn Bertozzi
Excellent story from @aniloza.bsky.social and colleague at STAT on the MOSAIC program.
www.statnews.com/2025/12/08/t...
1/4
www.statnews.com/2025/12/08/t...
1/4
NIH shut out hundreds of young scientists from funding to start their own labs
Special Report: The NIH has shut out hundreds of young scientists from funding to start their own labs.
www.statnews.com
December 8, 2025 at 2:48 PM
Excellent story from @aniloza.bsky.social and colleague at STAT on the MOSAIC program.
www.statnews.com/2025/12/08/t...
1/4
www.statnews.com/2025/12/08/t...
1/4
Reposted by Carolyn Bertozzi
The US is funding fewer grants compared to the past. The money is given in one lump sum instead a yearly infusion from a multi-year funded grant. This leads to more competition, less $ and time to do research. Not a win-win situation.
🧪🎁🔗 www.nytimes.com/interactive/...
🧪🎁🔗 www.nytimes.com/interactive/...
The U.S. Is Funding Fewer Grants in Every Area of Science and Medicine (Gift Article)
A quiet policy change means the government is making fewer bets on long-term science.
www.nytimes.com
December 7, 2025 at 7:49 PM
The US is funding fewer grants compared to the past. The money is given in one lump sum instead a yearly infusion from a multi-year funded grant. This leads to more competition, less $ and time to do research. Not a win-win situation.
🧪🎁🔗 www.nytimes.com/interactive/...
🧪🎁🔗 www.nytimes.com/interactive/...
Congratulations former postdoc @jfhevler.bsky.social (in transit to Roche) and the team on their work using thermal proteome profiling along with glycosylation perturbagens to discover glycan-dependent protein functions at the proteome scale 👏
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Discovering Glycosylation-Dependent Protein Function by Thermal Proteome Profiling
Protein glycosylation regulates essential cellular processes including protein folding, stability, and cell-cell interactions; however, how aberrant glycosylation impacts protein function and interact...
www.biorxiv.org
December 8, 2025 at 2:32 AM
Congratulations former postdoc @jfhevler.bsky.social (in transit to Roche) and the team on their work using thermal proteome profiling along with glycosylation perturbagens to discover glycan-dependent protein functions at the proteome scale 👏
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...