Elisa Fadda
@elisafadda.bsky.social
Associate Professor in the School of Biological Sciences at the University of Southampton, head chef at https://GlycoShape.org, Salem's butler, fucose fanatic #glycotime everyday! She/Her
Pinned
Elisa Fadda
@elisafadda.bsky.social
· Nov 13
As we (my lab and I) are new here 😻, let me introduce some exciting #glycotime work we recently published in Nature Methods doi.org/10.1038/s415... GlycoShape is a completely OA database and toolbox to restore the 3D structure of glycans on glycoproteins 🥳 You can find it at glycoshape.org 1/2
Reposted by Elisa Fadda
This a word cloud from the titles of ~1100 terminated NSF grants.
It is hard not to see these grant terminations as an attack on the training of the future United States scientific workforce.
It is hard not to see these grant terminations as an attack on the training of the future United States scientific workforce.
February 7, 2026 at 3:55 PM
This a word cloud from the titles of ~1100 terminated NSF grants.
It is hard not to see these grant terminations as an attack on the training of the future United States scientific workforce.
It is hard not to see these grant terminations as an attack on the training of the future United States scientific workforce.
Reposted by Elisa Fadda
A near-complete map of human cytosolic degrons and their relevance for disease
We measured degron potency of >200,000 30-residue tiles from >5,000 human proteins, and trained a model to predict degrons from sequence
Led by @vvouts.bsky.social in @rhp-lab.bsky.social
doi.org/10.1126/scia...
We measured degron potency of >200,000 30-residue tiles from >5,000 human proteins, and trained a model to predict degrons from sequence
Led by @vvouts.bsky.social in @rhp-lab.bsky.social
doi.org/10.1126/scia...
February 7, 2026 at 7:42 AM
A near-complete map of human cytosolic degrons and their relevance for disease
We measured degron potency of >200,000 30-residue tiles from >5,000 human proteins, and trained a model to predict degrons from sequence
Led by @vvouts.bsky.social in @rhp-lab.bsky.social
doi.org/10.1126/scia...
We measured degron potency of >200,000 30-residue tiles from >5,000 human proteins, and trained a model to predict degrons from sequence
Led by @vvouts.bsky.social in @rhp-lab.bsky.social
doi.org/10.1126/scia...
Reposted by Elisa Fadda
Fabulous talk by @fabianruperti.bsky.social in the #LorneProteomics2026 #glycotime session on the evolution and diversity of N-glycosylation in animals
February 7, 2026 at 5:00 AM
Fabulous talk by @fabianruperti.bsky.social in the #LorneProteomics2026 #glycotime session on the evolution and diversity of N-glycosylation in animals
Reposted by Elisa Fadda
February 6, 2026 at 7:22 AM
"What I can’t actually believe it has the barefaced gall to still have that phrase on its masthead though I liked this take from the Reductress, titled: The Washington Post Lays Off Half Its Slogan"
@carolecadwalla.bsky.social ⬇️👏🏻 👏🏻
open.substack.com/pub/broligar...
@carolecadwalla.bsky.social ⬇️👏🏻 👏🏻
open.substack.com/pub/broligar...
Fight!
Fuck Bezos. The Washington Post can and must rise again.
open.substack.com
February 6, 2026 at 7:23 AM
"What I can’t actually believe it has the barefaced gall to still have that phrase on its masthead though I liked this take from the Reductress, titled: The Washington Post Lays Off Half Its Slogan"
@carolecadwalla.bsky.social ⬇️👏🏻 👏🏻
open.substack.com/pub/broligar...
@carolecadwalla.bsky.social ⬇️👏🏻 👏🏻
open.substack.com/pub/broligar...
Reposted by Elisa Fadda
Have I ever mentioned how surreal it is to be an Editor-in-Chief of a journal called Vaccine right now?
www.science.org/content/arti...
It’s pretty wild, at least by typical academic journal editorial office standards.
www.science.org/content/arti...
It’s pretty wild, at least by typical academic journal editorial office standards.
Controversial Danish vaccine research group faces new allegations
Researchers say they couldn’t find complete data for 10 trials that together enrolled tens of thousands of children in Guinea-Bissau
www.science.org
February 6, 2026 at 6:14 AM
Have I ever mentioned how surreal it is to be an Editor-in-Chief of a journal called Vaccine right now?
www.science.org/content/arti...
It’s pretty wild, at least by typical academic journal editorial office standards.
www.science.org/content/arti...
It’s pretty wild, at least by typical academic journal editorial office standards.
Reposted by Elisa Fadda
@mikefeigin.bsky.social’s favorite bioRxiv experience was being able to start a collaboration based on reading a preprint, leading to a publication years later. As an Affiliate, he helps these impactful preprints be posted ~48 hours post-submission
#openRxiv #OpenScience #preprints #CommunityVoices
#openRxiv #OpenScience #preprints #CommunityVoices
February 5, 2026 at 6:04 PM
@mikefeigin.bsky.social’s favorite bioRxiv experience was being able to start a collaboration based on reading a preprint, leading to a publication years later. As an Affiliate, he helps these impactful preprints be posted ~48 hours post-submission
#openRxiv #OpenScience #preprints #CommunityVoices
#openRxiv #OpenScience #preprints #CommunityVoices
Reposted by Elisa Fadda
Listen to the second installment of the Lost Women of Science podcast series Layers of Brilliance digging into the life of Katharine Burr Blodgett, who began her career at the "House of Magic"
Katharine Burr Blodgett’s brilliant career began at the ‘House of Magic’
When a young Katharine Burr Blodgett joined future Nobel Prize winner Irving Langmuir at the General Electric Company’s industrial research laboratory in Schenectady, N.Y, it was the start of her bril...
www.scientificamerican.com
February 5, 2026 at 9:57 PM
Listen to the second installment of the Lost Women of Science podcast series Layers of Brilliance digging into the life of Katharine Burr Blodgett, who began her career at the "House of Magic"
Amazing 🇦🇺 #glycotime 🧪⬇️
🚨 Our new paper is out today in Nature Chemical Biology:
“Pan-specific antibodies to uncover bacterial pseudaminylation”
doi.org/10.1038/s415...
This is the product of a collaboration between many teams, led by @nickescott.bsky.social, @payneresearch.bsky.social and myself.
1/6
“Pan-specific antibodies to uncover bacterial pseudaminylation”
doi.org/10.1038/s415...
This is the product of a collaboration between many teams, led by @nickescott.bsky.social, @payneresearch.bsky.social and myself.
1/6
Uncovering bacterial pseudaminylation with pan-specific antibody tools - Nature Chemical Biology
Pseudaminic acids (Pse) are a family of carbohydrates found within bacterial lipopolysaccharides, capsular polysaccharides and glycoproteins. Now, monoclonal antibodies have been developed that recogn...
doi.org
February 5, 2026 at 8:56 PM
Amazing 🇦🇺 #glycotime 🧪⬇️
Reposted by Elisa Fadda
🚨 Our new paper is out today in Nature Chemical Biology:
“Pan-specific antibodies to uncover bacterial pseudaminylation”
doi.org/10.1038/s415...
This is the product of a collaboration between many teams, led by @nickescott.bsky.social, @payneresearch.bsky.social and myself.
1/6
“Pan-specific antibodies to uncover bacterial pseudaminylation”
doi.org/10.1038/s415...
This is the product of a collaboration between many teams, led by @nickescott.bsky.social, @payneresearch.bsky.social and myself.
1/6
Uncovering bacterial pseudaminylation with pan-specific antibody tools - Nature Chemical Biology
Pseudaminic acids (Pse) are a family of carbohydrates found within bacterial lipopolysaccharides, capsular polysaccharides and glycoproteins. Now, monoclonal antibodies have been developed that recogn...
doi.org
February 4, 2026 at 10:32 PM
🚨 Our new paper is out today in Nature Chemical Biology:
“Pan-specific antibodies to uncover bacterial pseudaminylation”
doi.org/10.1038/s415...
This is the product of a collaboration between many teams, led by @nickescott.bsky.social, @payneresearch.bsky.social and myself.
1/6
“Pan-specific antibodies to uncover bacterial pseudaminylation”
doi.org/10.1038/s415...
This is the product of a collaboration between many teams, led by @nickescott.bsky.social, @payneresearch.bsky.social and myself.
1/6
Reposted by Elisa Fadda
Really happy to see this work out!
Super fun project with a great team. For me the highlight was that we finally were able to show the O-linked glycosylation systems of H. pylori/C. jejuni are general glycosylation systems which target non-flagellin proteins (suggest >10 years ago by click chem).
Super fun project with a great team. For me the highlight was that we finally were able to show the O-linked glycosylation systems of H. pylori/C. jejuni are general glycosylation systems which target non-flagellin proteins (suggest >10 years ago by click chem).
🚨 Our new paper is out today in Nature Chemical Biology:
“Pan-specific antibodies to uncover bacterial pseudaminylation”
doi.org/10.1038/s415...
This is the product of a collaboration between many teams, led by @nickescott.bsky.social, @payneresearch.bsky.social and myself.
1/6
“Pan-specific antibodies to uncover bacterial pseudaminylation”
doi.org/10.1038/s415...
This is the product of a collaboration between many teams, led by @nickescott.bsky.social, @payneresearch.bsky.social and myself.
1/6
Uncovering bacterial pseudaminylation with pan-specific antibody tools - Nature Chemical Biology
Pseudaminic acids (Pse) are a family of carbohydrates found within bacterial lipopolysaccharides, capsular polysaccharides and glycoproteins. Now, monoclonal antibodies have been developed that recogn...
doi.org
February 5, 2026 at 7:12 PM
Really happy to see this work out!
Super fun project with a great team. For me the highlight was that we finally were able to show the O-linked glycosylation systems of H. pylori/C. jejuni are general glycosylation systems which target non-flagellin proteins (suggest >10 years ago by click chem).
Super fun project with a great team. For me the highlight was that we finally were able to show the O-linked glycosylation systems of H. pylori/C. jejuni are general glycosylation systems which target non-flagellin proteins (suggest >10 years ago by click chem).
Reposted by Elisa Fadda
‘Study after study shows that students want to develop these critical thinking skills, are not lazy, and large numbers of them would be in favor of banning ChatGPT and similar tools in universities’, says @olivia.science www.ru.nl/en/research/...
‘Opposing the inevitability of AI at universities is possible and necessary’ | Radboud University
Since the widespread release of ChatGPT in December of 2022, AI has taken over much of the world by storm – including academia. Most of this happened with very little pushback, despite a myriad of iss...
www.ru.nl
November 1, 2025 at 10:26 PM
‘Study after study shows that students want to develop these critical thinking skills, are not lazy, and large numbers of them would be in favor of banning ChatGPT and similar tools in universities’, says @olivia.science www.ru.nl/en/research/...
Reposted by Elisa Fadda
I’m having a hard time thinking of an interview between two human beings I enjoyed more than tonight’s interview of the great Ian McKellen by the great Stephen Colbert. Every moment of it was a pleasure that I highly recommend… but then came the most REMARKABLE ending that you really HAVE to watch.
"There's Nothing I Enjoy More Than Acting In The Theater" - Ian McKellen EXTENDED INTERVIEW
YouTube video by The Late Show with Stephen Colbert
youtube.com
February 5, 2026 at 7:26 AM
I’m having a hard time thinking of an interview between two human beings I enjoyed more than tonight’s interview of the great Ian McKellen by the great Stephen Colbert. Every moment of it was a pleasure that I highly recommend… but then came the most REMARKABLE ending that you really HAVE to watch.
Reposted by Elisa Fadda
'Still, publishing a review —often with its own DOI—raises questions about the review’s legal status as a standalone scholarly item as it could belong to the reviewer, the publisher or both, or enters the public domain under a CC license with unclear rights about who is allowed to do what.'
Peer-review ownership in the AI era - EMBO Reports
EMBO Reports - The peer review process is fundamental to scientific validation, yet ownership and permitted uses of the resulting content remain insufficiently defined. To ensure the future...
link.springer.com
February 4, 2026 at 1:36 PM
'Still, publishing a review —often with its own DOI—raises questions about the review’s legal status as a standalone scholarly item as it could belong to the reviewer, the publisher or both, or enters the public domain under a CC license with unclear rights about who is allowed to do what.'
Aside from the obvious reasons, there is also this 👇🏻👏🏻
One of the most effective things you can do right now to fight Trump and ICE is to cancel your ChatGPT subscription.
February 5, 2026 at 8:13 AM
Aside from the obvious reasons, there is also this 👇🏻👏🏻
Reposted by Elisa Fadda
Now on bioRxiv: genome‑wide CRISPR KO reveals BAG6 (chaperone) and RNF126 (E3) as core PQC for non‑native missense proteins. VAMP seq. shows >1000 Parkin variants are BAG6 targets, including known pathogenic variants. Work led by Line Pedersen. Collab with @lindorfflarsen.bsky.social
BAG6 and RNF126 are broadly involved in protein quality control of non-native missense protein variants https://www.biorxiv.org/content/10.64898/2026.02.04.703735v1
February 5, 2026 at 7:23 AM
Now on bioRxiv: genome‑wide CRISPR KO reveals BAG6 (chaperone) and RNF126 (E3) as core PQC for non‑native missense proteins. VAMP seq. shows >1000 Parkin variants are BAG6 targets, including known pathogenic variants. Work led by Line Pedersen. Collab with @lindorfflarsen.bsky.social
As replacing your brain + a good search on Google Scholar, this may be a useful LLM tool, except that "it does not consistently retrieve the most representative or relevant papers for certain queries" 🤔 and why is this in Nature, again? 🤔🤔
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Synthesizing scientific literature with retrieval-augmented language models - Nature
A specialized, open-source, retrieval-augmented language model is introduced for answering scientific queries and synthesizing literature, the responses of which are shown to be preferred by human eva...
www.nature.com
February 5, 2026 at 8:00 AM
As replacing your brain + a good search on Google Scholar, this may be a useful LLM tool, except that "it does not consistently retrieve the most representative or relevant papers for certain queries" 🤔 and why is this in Nature, again? 🤔🤔
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Elisa Fadda
Great story on Seung-Wuk Lee’s work on virus particle-based materials @berkeleyengineer.bsky.social #proudofalumni
ICYMI: @berkeleyengineer.bsky.social's Seung-Wuk Lee, a faculty scientist in #BioBSE, pioneered a sustainable biomining approach using genetically engineered viruses to extract rare earth elements. Read more: go.lbl.gov/biomining
February 4, 2026 at 11:13 PM
Great story on Seung-Wuk Lee’s work on virus particle-based materials @berkeleyengineer.bsky.social #proudofalumni
Reposted by Elisa Fadda
Landing in Dunedin Aotearoa in about 90 minutes for the start of a trip that represents the culmination of a dream I’ve had since I was ten years old.
Visiting academic to address spread of misinformation
For Carl Bergstrom, misinformation is like a living organism — it can travel across networks and spread through populations like pathogens. The...
www.odt.co.nz
February 4, 2026 at 11:43 PM
Landing in Dunedin Aotearoa in about 90 minutes for the start of a trip that represents the culmination of a dream I’ve had since I was ten years old.
Reposted by Elisa Fadda
INBOX: Robert McCartney, who worked for 39 years at The Washington Post, including as a Metro columnist and editor, before retiring in 2021, claims on X that he has heard the Post has laid off *all* its photojournalists.
February 4, 2026 at 9:05 PM
INBOX: Robert McCartney, who worked for 39 years at The Washington Post, including as a Metro columnist and editor, before retiring in 2021, claims on X that he has heard the Post has laid off *all* its photojournalists.
Reposted by Elisa Fadda
In no functioning country is this allowed.
Fucking surreal that people dressed like this and carrying assault rifles are permitted to kidnap people off our streets
February 4, 2026 at 4:16 AM
In no functioning country is this allowed.
Reposted by Elisa Fadda
Welcome, piles of slop filling up the journals with clouds of useless wordy garbage. Case in point:
What the Literature is Filling Up With
www.science.org
February 4, 2026 at 8:47 PM
Welcome, piles of slop filling up the journals with clouds of useless wordy garbage. Case in point:
Reposted by Elisa Fadda
PaperBanana: Automating Academic Illustration for AI Scientists
doi.org/10.48550/arX...
dwzhu-pku.github.io/PaperBanana/
doi.org/10.48550/arX...
dwzhu-pku.github.io/PaperBanana/
February 4, 2026 at 10:18 AM
PaperBanana: Automating Academic Illustration for AI Scientists
doi.org/10.48550/arX...
dwzhu-pku.github.io/PaperBanana/
doi.org/10.48550/arX...
dwzhu-pku.github.io/PaperBanana/
Reposted by Elisa Fadda
🚨BREAKING: The UK economy would be 3.6% smaller by 2040 if net migration fell to zero, forcing the government to raise taxes to combat a much bigger budget deficit, a thinktank has predicted.
www.theguardian.com/business/202...
www.theguardian.com/business/202...
February 4, 2026 at 9:09 AM
🚨BREAKING: The UK economy would be 3.6% smaller by 2040 if net migration fell to zero, forcing the government to raise taxes to combat a much bigger budget deficit, a thinktank has predicted.
www.theguardian.com/business/202...
www.theguardian.com/business/202...