See preprint for:
— Ensembles of >12000 full-length human proteins
— Analysis of IDRs in >1500 TFs
📜 doi.org/10.1101/2025...
💾 github.com/KULL-Centre/...
Violets are blue
If you fall in love with your hypothesis
You’ll be biased to prove it true
🧪
Violets are blue
If you fall in love with your hypothesis
You’ll be biased to prove it true
🧪
For me: 'et cetera'/'ecksetra'.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
You too can do this at:
implicit.harvard.edu/implicit/
You too can do this at:
implicit.harvard.edu/implicit/
Announcement:
www.isomorphiclabs.com/articles/the...
Report:
storage.googleapis.com/isomorphicla...
Announcement:
www.isomorphiclabs.com/articles/the...
Report:
storage.googleapis.com/isomorphicla...
www.biorxiv.org/content/10.6...
We measured degron potency of >200,000 30-residue tiles from >5,000 human proteins, and trained a model to predict degrons from sequence
Led by @vvouts.bsky.social in @rhp-lab.bsky.social
doi.org/10.1126/scia...
We measured degron potency of >200,000 30-residue tiles from >5,000 human proteins, and trained a model to predict degrons from sequence
Led by @vvouts.bsky.social in @rhp-lab.bsky.social
doi.org/10.1126/scia...
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
doi.org/10.64898/202...
doi.org/10.64898/202...
What better way of introducing the importance of protein disorder than by talking about this fellow
What better way of introducing the importance of protein disorder than by talking about this fellow
www.biorxiv.org/content/10.6... (w/ @sina.bio & @lauraluebbert.com).
www.biorxiv.org/content/10.6... (w/ @sina.bio & @lauraluebbert.com).
In a new preprint, we show how eLife’s Publish, Review, Curate model makes it possible to evaluate AI-generated reviews (with OpenEval) against human peer review. w/ @lauraluebbert.com and @lpachter.bsky.social
In a new preprint, we show how eLife’s Publish, Review, Curate model makes it possible to evaluate AI-generated reviews (with OpenEval) against human peer review. w/ @lauraluebbert.com and @lpachter.bsky.social
doi.org/10.48550/arX...
dwzhu-pku.github.io/PaperBanana/
doi.org/10.48550/arX...
dwzhu-pku.github.io/PaperBanana/
Learning Dynamic Protein Representations at Scale with Distograms
www.biorxiv.org/content/10.6...
Learning Dynamic Protein Representations at Scale with Distograms
www.biorxiv.org/content/10.6...
Spoiler: Mass-transport limitations. We find a strong correlation between diffusion and reaction rates.
doi.org/10.64898/202...
Spoiler: Mass-transport limitations. We find a strong correlation between diffusion and reaction rates.
doi.org/10.64898/202...
www.nature.com/articles/358...
www.nature.com/articles/358...
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
We present a data-driven “stickiness” scale for amino acids in intrinsically disordered proteins 🍝, learned from SAXS data on 115 proteins. The scale captures effective residue interactions without conflating size and strength
doi.org/10.64898/202...
We present a data-driven “stickiness” scale for amino acids in intrinsically disordered proteins 🍝, learned from SAXS data on 115 proteins. The scale captures effective residue interactions without conflating size and strength
doi.org/10.64898/202...