Matthieu Chavent
@matthchavent.bsky.social
Multiscale molecular dynamics, biological membranes interactions, CNRS researcher, group leader at @cbitoulouse.bsky.social
Pinned
🔬 MD community call! 🧪
Join us for the “Learn • Connect • Innovate” Co-Designing Workshop Series, part of the @lumen-eu.bsky.social project to shape the future of open science tools, workflows, and collaboration across disciplines.
lumenproject.eu/learn-connec...
Join us for the “Learn • Connect • Innovate” Co-Designing Workshop Series, part of the @lumen-eu.bsky.social project to shape the future of open science tools, workflows, and collaboration across disciplines.
lumenproject.eu/learn-connec...
Reposted by Matthieu Chavent
Understanding geometry through model making
November 6, 2025 at 5:51 PM
Understanding geometry through model making
Reposted by Matthieu Chavent
Fat storage in the body relies on specialized structures called lipid droplets. In a new Science study, researchers identified the microprotein adipogenin as a regulator of adipocyte lipid droplet size, revealing a key mechanism in lipid homeostasis.
Learn more this week: https://scim.ag/4nFEGO7
Learn more this week: https://scim.ag/4nFEGO7
November 6, 2025 at 7:05 PM
Fat storage in the body relies on specialized structures called lipid droplets. In a new Science study, researchers identified the microprotein adipogenin as a regulator of adipocyte lipid droplet size, revealing a key mechanism in lipid homeostasis.
Learn more this week: https://scim.ag/4nFEGO7
Learn more this week: https://scim.ag/4nFEGO7
Reposted by Matthieu Chavent
🚨Curious how synthetic fluorophores simplify microscopy? Our review covers applications such as super-resolution microscopy and biosensing. 🎉👩🔬Congrats to my first PhD student, Agnese Nicoli, for the fearless deep dive! 🔬 ⚗️
D-CHAB @ethz.ch
www.nature.com/articles/s41...
D-CHAB @ethz.ch
www.nature.com/articles/s41...
Synthetic fluorophores for live-cell fluorescence microscopy and biosensing - Nature Chemical Biology
Performing live-cell microscopy experiments with high spatial and temporal resolution requires fluorophores with highly optimized properties. This Review examines the progress in developing synthetic ...
www.nature.com
November 5, 2025 at 9:29 PM
🚨Curious how synthetic fluorophores simplify microscopy? Our review covers applications such as super-resolution microscopy and biosensing. 🎉👩🔬Congrats to my first PhD student, Agnese Nicoli, for the fearless deep dive! 🔬 ⚗️
D-CHAB @ethz.ch
www.nature.com/articles/s41...
D-CHAB @ethz.ch
www.nature.com/articles/s41...
Reposted by Matthieu Chavent
Glushkova, Böhm, & Beck @maxplanck.de develop a publicly available computational method to measure the thickness of biological membranes in cryo-electron tomograms. Analysis of algae & human cells reveals systematic membrane thickness variations within & across organelles rupress.org/jcb/article/...
November 4, 2025 at 5:30 PM
Glushkova, Böhm, & Beck @maxplanck.de develop a publicly available computational method to measure the thickness of biological membranes in cryo-electron tomograms. Analysis of algae & human cells reveals systematic membrane thickness variations within & across organelles rupress.org/jcb/article/...
Reposted by Matthieu Chavent
*If you would like to be considered for a talk at this workshop, please register & submit an abstract by 7 November*
We also have a fantastic line-up of invited speakers: Matteo Degiacomi, Lucie Delemotte, Weria Pezeshkian, Mohsen Sadeghi & Ilpo Vattulainen
Registration: aias.au.dk/events/show/...
We also have a fantastic line-up of invited speakers: Matteo Degiacomi, Lucie Delemotte, Weria Pezeshkian, Mohsen Sadeghi & Ilpo Vattulainen
Registration: aias.au.dk/events/show/...
November 4, 2025 at 11:46 AM
*If you would like to be considered for a talk at this workshop, please register & submit an abstract by 7 November*
We also have a fantastic line-up of invited speakers: Matteo Degiacomi, Lucie Delemotte, Weria Pezeshkian, Mohsen Sadeghi & Ilpo Vattulainen
Registration: aias.au.dk/events/show/...
We also have a fantastic line-up of invited speakers: Matteo Degiacomi, Lucie Delemotte, Weria Pezeshkian, Mohsen Sadeghi & Ilpo Vattulainen
Registration: aias.au.dk/events/show/...
Reposted by Matthieu Chavent
Localization of the #septin #cytoskeleton is controlled by regulatory factors, membrane curvature, & charge. In this study, @gladfelterlab.bsky.social finds changes to #lipid composition that modulate lipid packing defects to impact septin assemblies in vitro & in cells. rupress.org/jcb/article/...
November 3, 2025 at 5:01 PM
Localization of the #septin #cytoskeleton is controlled by regulatory factors, membrane curvature, & charge. In this study, @gladfelterlab.bsky.social finds changes to #lipid composition that modulate lipid packing defects to impact septin assemblies in vitro & in cells. rupress.org/jcb/article/...
🔬 CECAM Workshop: “Integrative and Multiscale Modelling Approaches to Illuminate CryoEM/ET Data”
Join us in Toulouse, 24–26 March 2026, to explore how molecular simulations, AI tools, can be integrated to cryo-EM and cryo-ET data.
🧬 Selection: brief CV + motivation letter required.
Apply 👇
Join us in Toulouse, 24–26 March 2026, to explore how molecular simulations, AI tools, can be integrated to cryo-EM and cryo-ET data.
🧬 Selection: brief CV + motivation letter required.
Apply 👇
CECAM - Integrative and Multiscale Modelling Approaches to Illuminate CryoEM/ET data
www.cecam.org
November 1, 2025 at 9:47 AM
🔬 CECAM Workshop: “Integrative and Multiscale Modelling Approaches to Illuminate CryoEM/ET Data”
Join us in Toulouse, 24–26 March 2026, to explore how molecular simulations, AI tools, can be integrated to cryo-EM and cryo-ET data.
🧬 Selection: brief CV + motivation letter required.
Apply 👇
Join us in Toulouse, 24–26 March 2026, to explore how molecular simulations, AI tools, can be integrated to cryo-EM and cryo-ET data.
🧬 Selection: brief CV + motivation letter required.
Apply 👇
MD community, do you want to help designing new tools for MD data search. Please sign up! 👇
Your research expertise meets LUMEN’s tool development - join our co-design workshops! 👇
Workshop Topic #7:
Meta-search & discovery tools
Sign up here: https://ow.ly/IE6k50XgcN1
Workshop Topic #7:
Meta-search & discovery tools
Sign up here: https://ow.ly/IE6k50XgcN1
October 29, 2025 at 1:27 PM
MD community, do you want to help designing new tools for MD data search. Please sign up! 👇
Reposted by Matthieu Chavent
#compchem #machinelearning #quantumcomputing
We have several open positions & we are looking for:
- 2 postdocs in machine learning to work on foundation models (theoretical developments)
- 2 HPC engineers: quantum computing(1); ab initio computations and QM/MM (2)
Reach to me for more details.
We have several open positions & we are looking for:
- 2 postdocs in machine learning to work on foundation models (theoretical developments)
- 2 HPC engineers: quantum computing(1); ab initio computations and QM/MM (2)
Reach to me for more details.
October 29, 2025 at 6:51 AM
#compchem #machinelearning #quantumcomputing
We have several open positions & we are looking for:
- 2 postdocs in machine learning to work on foundation models (theoretical developments)
- 2 HPC engineers: quantum computing(1); ab initio computations and QM/MM (2)
Reach to me for more details.
We have several open positions & we are looking for:
- 2 postdocs in machine learning to work on foundation models (theoretical developments)
- 2 HPC engineers: quantum computing(1); ab initio computations and QM/MM (2)
Reach to me for more details.
Reposted by Matthieu Chavent
#ACSChemBio and #Biochemistry invite submissions to a special issue on Lipids and Lipidation guest edited by @chembiobryan.bsky.social and me! Find details in the #CallforPapers and submit your exciting findings to one of these journals by May 31, 2026. axial.acs.org/chemical-bio... #lipidtime
Call for Papers: Lipids and Lipidation | ACS Publications Chemistry Blog
This Special Issue in _ACS Chemical Biology_ will highlight the latest advancements and perspectives in the chemical biology of lipids and lipidation. Submit your manuscript by May 31, 2026.
axial.acs.org
October 28, 2025 at 3:48 PM
#ACSChemBio and #Biochemistry invite submissions to a special issue on Lipids and Lipidation guest edited by @chembiobryan.bsky.social and me! Find details in the #CallforPapers and submit your exciting findings to one of these journals by May 31, 2026. axial.acs.org/chemical-bio... #lipidtime
Reposted by Matthieu Chavent
Passionate about GPCRs and molecular pharmacology? We’re looking for a PDRA to use computational molecular modelling and in vitro approaches (BRET etc) to uncover how the nitazene classe of synthetic opioids work.
Learn more and apply: www.bristol.ac.uk/jobs/find/de...
Reposts appreciated!
Learn more and apply: www.bristol.ac.uk/jobs/find/de...
Reposts appreciated!
October 24, 2025 at 3:09 PM
Passionate about GPCRs and molecular pharmacology? We’re looking for a PDRA to use computational molecular modelling and in vitro approaches (BRET etc) to uncover how the nitazene classe of synthetic opioids work.
Learn more and apply: www.bristol.ac.uk/jobs/find/de...
Reposts appreciated!
Learn more and apply: www.bristol.ac.uk/jobs/find/de...
Reposts appreciated!
Physics-based evolution of transmembrane helices reveals mechanisms of cholesterol attraction
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Physics-based evolution of transmembrane helices reveals mechanisms of cholesterol attraction - Nature Communications
Cholesterol plays a key role in membrane biology. Here, authors employ evolutionary molecular dynamics simulations to explore interactions driven by linear protein sequences, challenging the predictiv...
www.nature.com
October 24, 2025 at 5:33 AM
Physics-based evolution of transmembrane helices reveals mechanisms of cholesterol attraction
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Back to Oxford!
October 23, 2025 at 8:20 AM
Back to Oxford!
Reposted by Matthieu Chavent
🚨🚨🚨 We are launching the 2nd application round for the Erasmus Mundus Joint Master’s Program MemBioMed, offering cutting-edge training on exploring the complex behavior of cellular membranes & unlocking their therapeutic potential. Students can apply here: life.univ-cotedazur.eu/internationa...
October 17, 2025 at 3:18 PM
🚨🚨🚨 We are launching the 2nd application round for the Erasmus Mundus Joint Master’s Program MemBioMed, offering cutting-edge training on exploring the complex behavior of cellular membranes & unlocking their therapeutic potential. Students can apply here: life.univ-cotedazur.eu/internationa...
Reposted by Matthieu Chavent
Do you want to invent the future of Chemistry with us? We‘re looking for a "Digital Native” Organic Chemist to join our team at Microsoft Research AI for Science. We offer an amazing environment where you can do deep research with passionate and talented colleagues to solve problems that matter! 1/2
October 16, 2025 at 10:06 PM
Do you want to invent the future of Chemistry with us? We‘re looking for a "Digital Native” Organic Chemist to join our team at Microsoft Research AI for Science. We offer an amazing environment where you can do deep research with passionate and talented colleagues to solve problems that matter! 1/2
Reposted by Matthieu Chavent
The 3rd Annual Danish Workshop on Advanced Molecular Simulation. This time in Aarhus
Registration now open for the '3rd Annual Danish Workshop on Advanced Molecular Simulation'
Join us in beautiful Aarhus for a 2-day workshop on biomolecular simulations!
9-10 December 2025
Link for registration: aias.au.dk/events/show/...
Join us in beautiful Aarhus for a 2-day workshop on biomolecular simulations!
9-10 December 2025
Link for registration: aias.au.dk/events/show/...
October 15, 2025 at 7:53 PM
The 3rd Annual Danish Workshop on Advanced Molecular Simulation. This time in Aarhus
Reposted by Matthieu Chavent
Happy to finally see The Lipid Brain Atlas out! Lipids are not boring at all so, check it out!
Amazing team effort between computational and experimental work, led by @lucafusarbassini.bsky.social with @gioelelamanno.bsky.social and @giodang.bsky.social labs. Proud to be part of it.
Lipids rule!
Amazing team effort between computational and experimental work, led by @lucafusarbassini.bsky.social with @gioelelamanno.bsky.social and @giodang.bsky.social labs. Proud to be part of it.
Lipids rule!
🧠 The Lipid #Brain Atlas is out now! If you think #lipids are boring and membranes are all the same, prepare to be surprised. Led by @lucafusarbassini.bsky.social with Giovanni D'Angelo's lab, we mapped membrane lipids in the mouse brain at high resolution.
www.biorxiv.org/cgi/content/...
www.biorxiv.org/cgi/content/...
October 16, 2025 at 12:32 PM
Happy to finally see The Lipid Brain Atlas out! Lipids are not boring at all so, check it out!
Amazing team effort between computational and experimental work, led by @lucafusarbassini.bsky.social with @gioelelamanno.bsky.social and @giodang.bsky.social labs. Proud to be part of it.
Lipids rule!
Amazing team effort between computational and experimental work, led by @lucafusarbassini.bsky.social with @gioelelamanno.bsky.social and @giodang.bsky.social labs. Proud to be part of it.
Lipids rule!
Happy to be at the @cecamevents.bsky.social workshop on "When data science meets molecular dynamics"
We will have three days of interedting and lively discussions!!
Thank Adam, Eril, and Modesto for the invitation.
We will have three days of interedting and lively discussions!!
Thank Adam, Eril, and Modesto for the invitation.
October 15, 2025 at 8:34 AM
Happy to be at the @cecamevents.bsky.social workshop on "When data science meets molecular dynamics"
We will have three days of interedting and lively discussions!!
Thank Adam, Eril, and Modesto for the invitation.
We will have three days of interedting and lively discussions!!
Thank Adam, Eril, and Modesto for the invitation.
Reposted by Matthieu Chavent
Bacterial cell envelope-targeting antibiotics | Nature Reviews Microbiology https://www.nature.com/articles/s41579-025-01247-x
Bacterial cell envelope-targeting antibiotics - Nature Reviews Microbiology
In this Review, Weingarth and colleagues discuss both recently discovered compounds and established envelope-targeting antibiotics, including compounds that target Gram-positive bacteria, more complex Gram-negative bacteria and mycobacterial pathogens, with a particular focus on their drug–target interactions.
www.nature.com
October 14, 2025 at 12:02 AM
Bacterial cell envelope-targeting antibiotics | Nature Reviews Microbiology https://www.nature.com/articles/s41579-025-01247-x
Reposted by Matthieu Chavent
Thanks to @snsf.ch, we are hiring two PhD students to investigate frontier topics in lipid biology using a combination of MD simulations and experiments. Preferred starting date: ASAP. Fribourg - and Switzerland - are quite nice, for both work and private life! Please spread the word!
October 13, 2025 at 2:17 PM
Thanks to @snsf.ch, we are hiring two PhD students to investigate frontier topics in lipid biology using a combination of MD simulations and experiments. Preferred starting date: ASAP. Fribourg - and Switzerland - are quite nice, for both work and private life! Please spread the word!
Reposted by Matthieu Chavent
5 million of them are about research
October 13, 2025 at 11:19 AM
5 million of them are about research
Our collaborative work with W Im lab is now published as V1 in @elife.bsky.social alongside with reviewers comments.
We will update this version to answer to reviewers comment but we believe that this version is already a good start to understand mycomembrane structure!
doi.org/10.7554/eLif...
We will update this version to answer to reviewers comment but we believe that this version is already a good start to understand mycomembrane structure!
doi.org/10.7554/eLif...
Dynamic Architecture of Mycobacterial Outer Membranes Revealed by All-Atom Simulations
doi.org
October 11, 2025 at 7:43 AM
Our collaborative work with W Im lab is now published as V1 in @elife.bsky.social alongside with reviewers comments.
We will update this version to answer to reviewers comment but we believe that this version is already a good start to understand mycomembrane structure!
doi.org/10.7554/eLif...
We will update this version to answer to reviewers comment but we believe that this version is already a good start to understand mycomembrane structure!
doi.org/10.7554/eLif...
Reposted by Matthieu Chavent
Ever wondered how adult organs preserve epithelial barrier integrity while continuously exposed to mechanical stress? We tackled this question in our new preprint – led by our brilliant PhD student Vishnu Krishnakumar! (1/11)
🔗 www.biorxiv.org/content/10.1...
🔗 www.biorxiv.org/content/10.1...
Robust pan-junctional reinforcement preserves the gut epithelial barrier under mechanical stress
Epithelia are specialized tissue barriers that safeguard the organism's internal milieu from the hostile external environment, a function critically dependent on intercellular junctions. In the colon,...
www.biorxiv.org
October 8, 2025 at 9:52 PM
Ever wondered how adult organs preserve epithelial barrier integrity while continuously exposed to mechanical stress? We tackled this question in our new preprint – led by our brilliant PhD student Vishnu Krishnakumar! (1/11)
🔗 www.biorxiv.org/content/10.1...
🔗 www.biorxiv.org/content/10.1...
Reposted by Matthieu Chavent
Learn all things #cytoskeleton #research in an interdisciplinary environment at EMBO Workshop "Structure and Function of the Cytoskeleton" in Paris, FR, 7–10 April 2026.
Deadline: 20 December 2025
https://meetings.embo.org/event/26-cytoskeleton
#EMBOCytoskeletalFunction #EMBOevents #conference 🧪
Deadline: 20 December 2025
https://meetings.embo.org/event/26-cytoskeleton
#EMBOCytoskeletalFunction #EMBOevents #conference 🧪
Structure and Function of the Cytoskeleton
The cytoskeleton, a dynamic and intricate network of protein filaments, is found within the cytoplasm of all cells, from bacteria and archaea to complex eukaryotes. This essential cellular component …
meetings.embo.org
October 7, 2025 at 3:35 PM
Learn all things #cytoskeleton #research in an interdisciplinary environment at EMBO Workshop "Structure and Function of the Cytoskeleton" in Paris, FR, 7–10 April 2026.
Deadline: 20 December 2025
https://meetings.embo.org/event/26-cytoskeleton
#EMBOCytoskeletalFunction #EMBOevents #conference 🧪
Deadline: 20 December 2025
https://meetings.embo.org/event/26-cytoskeleton
#EMBOCytoskeletalFunction #EMBOevents #conference 🧪
Reposted by Matthieu Chavent
October 6, 2025 at 1:06 AM