John Chodera
@jchodera.bsky.social
Achira | http://achira.ai
Research laboratory | http://choderalab.org
Antiviral drug discovery for pandemics | http://asapdiscovery.org
OpenADMET | http://openadmet.org
Employer-mandated disclaimer: http://choderalab.org/disclaimer
Pronouns: he/him
Research laboratory | http://choderalab.org
Antiviral drug discovery for pandemics | http://asapdiscovery.org
OpenADMET | http://openadmet.org
Employer-mandated disclaimer: http://choderalab.org/disclaimer
Pronouns: he/him
Pinned
John Chodera
@jchodera.bsky.social
· Sep 24
Great news! 🎉
Following an independent expert review, we have formally nominated the broad-spectrum pan-coronavirus antiviral ASAP-0017445 as a pre-clinical drug candidate.
🔗Read the press release here: dndi.org/press-releas...
Following an independent expert review, we have formally nominated the broad-spectrum pan-coronavirus antiviral ASAP-0017445 as a pre-clinical drug candidate.
🔗Read the press release here: dndi.org/press-releas...
Incredibly proud to have played a small role in this journey alongside so many incredible scientists like Annette von Delft and Peter Sjö!
Reposted by John Chodera
"My father remained at the Texas detention center until October. During those six months, he went completely blind in one eye and lost most of the vision in the other, because he wasn’t receiving adequate medical care for his Type 2 diabetes."
From @vanessalop.bsky.social: He worked hard to give me a home. ICE took his: How I lost my father to deportation
chicago.suntimes.com/columnists/2...
chicago.suntimes.com/columnists/2...
He worked hard to give me a home. ICE took his: How I lost my father to deportation
Deportation has taken away the father I once knew and given me back a person I no longer recognize.
chicago.suntimes.com
November 10, 2025 at 9:06 PM
"My father remained at the Texas detention center until October. During those six months, he went completely blind in one eye and lost most of the vision in the other, because he wasn’t receiving adequate medical care for his Type 2 diabetes."
Reposted by John Chodera
Remember the Living Computing Museum? Then you should support and visit the Interim Computer Museum right near the Seattle Airport! Check out this special video I did with curator Stephen Jones and consider a matching donation - support the ICM! Please share! www.youtube.com/watch?v=EFkx...
The Past Still Boots with the Interim Computing Museum's Stephen Jones
YouTube video by Scott Hanselman
www.youtube.com
November 10, 2025 at 11:42 PM
Remember the Living Computing Museum? Then you should support and visit the Interim Computer Museum right near the Seattle Airport! Check out this special video I did with curator Stephen Jones and consider a matching donation - support the ICM! Please share! www.youtube.com/watch?v=EFkx...
Reposted by John Chodera
In the century leading up to 1975, nearly 6000 freighters went down in the Great Lakes.
The Edmund Fitzgerald was the last.
The last. In 50 years, not a single commercial freighter has been lost in the Great Lakes.
Why?
It's NOAA. Of course it's NOAA.
The Edmund Fitzgerald was the last.
The last. In 50 years, not a single commercial freighter has been lost in the Great Lakes.
Why?
It's NOAA. Of course it's NOAA.
November 11, 2025 at 1:50 AM
In the century leading up to 1975, nearly 6000 freighters went down in the Great Lakes.
The Edmund Fitzgerald was the last.
The last. In 50 years, not a single commercial freighter has been lost in the Great Lakes.
Why?
It's NOAA. Of course it's NOAA.
The Edmund Fitzgerald was the last.
The last. In 50 years, not a single commercial freighter has been lost in the Great Lakes.
Why?
It's NOAA. Of course it's NOAA.
Reposted by John Chodera
Democrats Sick Of Being Blamed For Cowardice On Issues They Actually Just Don’t Care About
Democrats Sick Of Being Blamed For Cowardice On Issues They Actually Just Don’t Care About
WASHINGTON—Having thus far caved on eliminating the filibuster, advancing an adequate climate change agenda, and protecting voting rights, congressional Democrats told reporters Wednesday they were si...
theonion.com
November 10, 2025 at 5:00 PM
Democrats Sick Of Being Blamed For Cowardice On Issues They Actually Just Don’t Care About
Reposted by John Chodera
Chuck Schumer Helps Pull Democrats Back From Brink Of Courage
November 10, 2025 at 5:02 AM
Chuck Schumer Helps Pull Democrats Back From Brink Of Courage
Reposted by John Chodera
Keep organizing, y’all. It is, and always has been, on all of us.
• Get connected to the resistance:
www.fiftyfifty.one
• Get trained on noncooperation:
nokings.org/rise
• Get bold for rapid response:
nokings.org/next
• Get engaged in politics:
pol-rev.com
• Get started:
Choosedemocracy.us
• Get connected to the resistance:
www.fiftyfifty.one
• Get trained on noncooperation:
nokings.org/rise
• Get bold for rapid response:
nokings.org/next
• Get engaged in politics:
pol-rev.com
• Get started:
Choosedemocracy.us
November 10, 2025 at 3:55 AM
Keep organizing, y’all. It is, and always has been, on all of us.
• Get connected to the resistance:
www.fiftyfifty.one
• Get trained on noncooperation:
nokings.org/rise
• Get bold for rapid response:
nokings.org/next
• Get engaged in politics:
pol-rev.com
• Get started:
Choosedemocracy.us
• Get connected to the resistance:
www.fiftyfifty.one
• Get trained on noncooperation:
nokings.org/rise
• Get bold for rapid response:
nokings.org/next
• Get engaged in politics:
pol-rev.com
• Get started:
Choosedemocracy.us
Reposted by John Chodera
Reposted by John Chodera
It is almost impossible to emphasize how unprofessional this is. Immigration enforcement agents pepper sprayed a car driving in the opposite direction, which was in no way a threat to them, hitting a toddler.
www.chicagotribune.com/2025/11/09/c...
www.chicagotribune.com/2025/11/09/c...
Pepper-sprayed Berwyn family rattled after getting caught up in federal blitz
Southwest Side politicians condemned Saturday’s pepper spraying and the federal sweep of Little Village as “state-sponsored terrorism” at a news conference Sunday.
www.chicagotribune.com
November 10, 2025 at 4:02 AM
It is almost impossible to emphasize how unprofessional this is. Immigration enforcement agents pepper sprayed a car driving in the opposite direction, which was in no way a threat to them, hitting a toddler.
www.chicagotribune.com/2025/11/09/c...
www.chicagotribune.com/2025/11/09/c...
Reposted by John Chodera
There is no hell hot enough for the administration demanding clawbacks from SNAP recipients. This is shockingly evil, especially only a few weeks away from a “holiday” where people who have the means will brag about eating so much they have to take off their belts and sleep by 4pm.
I've added this update to my story about the ongoing torture of SNAP recipients:
November 9, 2025 at 4:36 PM
There is no hell hot enough for the administration demanding clawbacks from SNAP recipients. This is shockingly evil, especially only a few weeks away from a “holiday” where people who have the means will brag about eating so much they have to take off their belts and sleep by 4pm.
Reposted by John Chodera
SNAP update. Insane one. So USDA is now saying on a huge lag:
- issue partial payments using a bad-math formula;
- CLAW BACK full issuances that any state sent *properly* under last week's guidance;
- if you don't CLAW BACK benefits, we won't pay the federal share of SNAP administrative costs (??)
- issue partial payments using a bad-math formula;
- CLAW BACK full issuances that any state sent *properly* under last week's guidance;
- if you don't CLAW BACK benefits, we won't pay the federal share of SNAP administrative costs (??)
November 9, 2025 at 3:37 PM
SNAP update. Insane one. So USDA is now saying on a huge lag:
- issue partial payments using a bad-math formula;
- CLAW BACK full issuances that any state sent *properly* under last week's guidance;
- if you don't CLAW BACK benefits, we won't pay the federal share of SNAP administrative costs (??)
- issue partial payments using a bad-math formula;
- CLAW BACK full issuances that any state sent *properly* under last week's guidance;
- if you don't CLAW BACK benefits, we won't pay the federal share of SNAP administrative costs (??)
Reposted by John Chodera
Reposted by John Chodera
And now, if you read the devastating piece about what Venezuelan deportees endured at the El Salvador torture prison, read what incarcerated U.S. citizens endure in Alabama prisons.
State prisons in the U.S. that are massive systems of human rights violations.
www.theguardian.com/film/2025/oc...
State prisons in the U.S. that are massive systems of human rights violations.
www.theguardian.com/film/2025/oc...
‘How is this possible?’: a new film looks inside the appalling abuses of the Alabama prison system
In the year’s most shocking documentary, The Alabama Solution, prisoners share astonishing footage in a plea for help
www.theguardian.com
November 9, 2025 at 4:38 PM
And now, if you read the devastating piece about what Venezuelan deportees endured at the El Salvador torture prison, read what incarcerated U.S. citizens endure in Alabama prisons.
State prisons in the U.S. that are massive systems of human rights violations.
www.theguardian.com/film/2025/oc...
State prisons in the U.S. that are massive systems of human rights violations.
www.theguardian.com/film/2025/oc...
Reposted by John Chodera
It would cost $38 billion dollars to extend the Affordable Care Act subsidies for another year and ensure Americans don’t lose their healthcare.
The republicans said no.
Trump sent $40 billion to Argentina and they didn’t object.
Argentina first, America last.
The republicans said no.
Trump sent $40 billion to Argentina and they didn’t object.
Argentina first, America last.
November 9, 2025 at 4:34 AM
It would cost $38 billion dollars to extend the Affordable Care Act subsidies for another year and ensure Americans don’t lose their healthcare.
The republicans said no.
Trump sent $40 billion to Argentina and they didn’t object.
Argentina first, America last.
The republicans said no.
Trump sent $40 billion to Argentina and they didn’t object.
Argentina first, America last.
Reposted by John Chodera
Counterpoint: maybe Watson was a misogynist and a racist from the start and shouldn’t have had any sterling reputation to begin with. This is him, in his own words, on Rosalind Franklin.
(Robert recalled an even worse story involving Franklin, which I haven’t read for myself.)
(Robert recalled an even worse story involving Franklin, which I haven’t read for myself.)
November 9, 2025 at 3:08 AM
Counterpoint: maybe Watson was a misogynist and a racist from the start and shouldn’t have had any sterling reputation to begin with. This is him, in his own words, on Rosalind Franklin.
(Robert recalled an even worse story involving Franklin, which I haven’t read for myself.)
(Robert recalled an even worse story involving Franklin, which I haven’t read for myself.)
Reposted by John Chodera
Oh yeah, they spent it.
Link below to the source in my mentions.
Link below to the source in my mentions.
November 9, 2025 at 2:14 AM
Oh yeah, they spent it.
Link below to the source in my mentions.
Link below to the source in my mentions.
Reposted by John Chodera
I met James Watson at a local conference in graduate school.
Watson apparently “over-learned that his bad manners were tolerated because of the greatness of the discovery he had made.”
Kindness is a legacy that he failed to leave.
🧪 www.statnews.com/2025/11/07/j...
Watson apparently “over-learned that his bad manners were tolerated because of the greatness of the discovery he had made.”
Kindness is a legacy that he failed to leave.
🧪 www.statnews.com/2025/11/07/j...
James Watson, dead at 97, was a scientific legend and a pariah among his peers
James Watson, the co-discoverer of the structure of DNA who died Thursday at 97, was a scientific legend and a pariah among his peers.
www.statnews.com
November 9, 2025 at 2:23 AM
I met James Watson at a local conference in graduate school.
Watson apparently “over-learned that his bad manners were tolerated because of the greatness of the discovery he had made.”
Kindness is a legacy that he failed to leave.
🧪 www.statnews.com/2025/11/07/j...
Watson apparently “over-learned that his bad manners were tolerated because of the greatness of the discovery he had made.”
Kindness is a legacy that he failed to leave.
🧪 www.statnews.com/2025/11/07/j...
Reposted by John Chodera
Jeremy, I have followed your science advocacy on this platform with respect, but I find this thread deeply hurtful and sad and I am going to tell you why. While my wife did her postdoc at CSHL, she and our many dear friends had to endure the racist rhetoric of this man, which did constant harm
On one evening, the speakers were divided up and went to dinner parties hosted by some of the wealthy folks who lived around Cold Spring Harbor on Long Island. My dinner was delightful, with good conversation with our host (the mayor of a nearby village), his friends, and some other speakers.
34/41
34/41
November 8, 2025 at 5:15 PM
Jeremy, I have followed your science advocacy on this platform with respect, but I find this thread deeply hurtful and sad and I am going to tell you why. While my wife did her postdoc at CSHL, she and our many dear friends had to endure the racist rhetoric of this man, which did constant harm
Reposted by John Chodera
Trump on SNAP: “Our country has to remain very liquid because of problems, catastrophes, wars… We have to remain liquid. We can’t give everything away.”
REMINDER: Trump just have $40 billion away to Argentina.
REMINDER: Trump just have $40 billion away to Argentina.
November 8, 2025 at 12:42 AM
Trump on SNAP: “Our country has to remain very liquid because of problems, catastrophes, wars… We have to remain liquid. We can’t give everything away.”
REMINDER: Trump just have $40 billion away to Argentina.
REMINDER: Trump just have $40 billion away to Argentina.
Reposted by John Chodera
This City Belongs to You.
YouTube video by Zohran Mamdani for NYC
youtu.be
November 7, 2025 at 1:13 PM
Reposted by John Chodera
HE'S APPEALING TO THE SUPREME COURT OF THE UNITED STATES THAT HE BE ALLOWED TO STARVE AMERICANS
November 7, 2025 at 11:50 PM
HE'S APPEALING TO THE SUPREME COURT OF THE UNITED STATES THAT HE BE ALLOWED TO STARVE AMERICANS
Reposted by John Chodera
Nov 7th is the birthday of both Lise Meitner & Marie Curie. Of the 13 chemical elements named directly after real people (not mythological figures) only two are named after women: meitnerium and curium (the latter of which is named in honour of both Marie & her husband) #chemsky 🧪
November 7, 2025 at 9:49 PM
Nov 7th is the birthday of both Lise Meitner & Marie Curie. Of the 13 chemical elements named directly after real people (not mythological figures) only two are named after women: meitnerium and curium (the latter of which is named in honour of both Marie & her husband) #chemsky 🧪
Reposted by John Chodera
Please, please, please take a few minutes to read this and share with colleagues. We are in a *critical* moment. If we all take a stand right now, we can avoid some version of this fate.
Notes from the first Gov led faculty meeting in Nazi Germany:
www.facinghistory.org/resource-lib...
Notes from the first Gov led faculty meeting in Nazi Germany:
www.facinghistory.org/resource-lib...
November 7, 2025 at 11:18 PM
Please, please, please take a few minutes to read this and share with colleagues. We are in a *critical* moment. If we all take a stand right now, we can avoid some version of this fate.
Notes from the first Gov led faculty meeting in Nazi Germany:
www.facinghistory.org/resource-lib...
Notes from the first Gov led faculty meeting in Nazi Germany:
www.facinghistory.org/resource-lib...
Reposted by John Chodera
Hey folks, as news of Watson's demise spreads, please don't set aside his weighty legacy of misogyny and racism. He was truly among the worst of us. www.vox.com/2019/1/15/18...
DNA scientist James Watson has a remarkably long history of sexist, racist public comments
“People say it would be terrible if we made all girls pretty,” he said in 2003. “I think it would be great.”
www.vox.com
November 7, 2025 at 7:45 PM
Hey folks, as news of Watson's demise spreads, please don't set aside his weighty legacy of misogyny and racism. He was truly among the worst of us. www.vox.com/2019/1/15/18...
Reposted by John Chodera
This is the facility that I and many others have been protesting. We’ve been hit, thrown, gassed, and shot with pepper bullets but none of that holds a candle to what is being done to people *in* the actual facility.
Read this thread. Don’t look away. Keep your eyes and the pressure on Broadview.
Read this thread. Don’t look away. Keep your eyes and the pressure on Broadview.
A family friend was telling us about what her husband shared about his experience in Broadview before he was deported back to Mexico. She's been sharing to friends and family because she's just in disbelief & horror what her husband told her. She wasn't able to talk to him until he was in Mexico.
November 7, 2025 at 3:29 PM
This is the facility that I and many others have been protesting. We’ve been hit, thrown, gassed, and shot with pepper bullets but none of that holds a candle to what is being done to people *in* the actual facility.
Read this thread. Don’t look away. Keep your eyes and the pressure on Broadview.
Read this thread. Don’t look away. Keep your eyes and the pressure on Broadview.