John Chodera
@jchodera.bsky.social
Achira | http://achira.ai
Research laboratory | http://choderalab.org
Antiviral drug discovery for pandemics | http://asapdiscovery.org
OpenADMET | http://openadmet.org
Employer-mandated disclaimer: http://choderalab.org/disclaimer
Pronouns: he/him
Research laboratory | http://choderalab.org
Antiviral drug discovery for pandemics | http://asapdiscovery.org
OpenADMET | http://openadmet.org
Employer-mandated disclaimer: http://choderalab.org/disclaimer
Pronouns: he/him
Pinned
John Chodera
@jchodera.bsky.social
· Sep 24
Great news! 🎉
Following an independent expert review, we have formally nominated the broad-spectrum pan-coronavirus antiviral ASAP-0017445 as a pre-clinical drug candidate.
🔗Read the press release here: dndi.org/press-releas...
Following an independent expert review, we have formally nominated the broad-spectrum pan-coronavirus antiviral ASAP-0017445 as a pre-clinical drug candidate.
🔗Read the press release here: dndi.org/press-releas...
Incredibly proud to have played a small role in this journey alongside so many incredible scientists like Annette von Delft and Peter Sjö!
Reposted by John Chodera
Congressional Republicans gave Trump a slush fund for ICE and CBP in the "Big Beautiful Bill." Tens of billions of dollars that is still usable even during a shutdown.
Democrats must make rescinding that money the price of any future govt funding, as Republicans did with IRS money from the IRA.
Democrats must make rescinding that money the price of any future govt funding, as Republicans did with IRS money from the IRA.
January 25, 2026 at 4:36 PM
Congressional Republicans gave Trump a slush fund for ICE and CBP in the "Big Beautiful Bill." Tens of billions of dollars that is still usable even during a shutdown.
Democrats must make rescinding that money the price of any future govt funding, as Republicans did with IRS money from the IRA.
Democrats must make rescinding that money the price of any future govt funding, as Republicans did with IRS money from the IRA.
Reposted by John Chodera
Voting NO on the DHS funding bill is the bare minimum.
Backing Kristi Noem’s impeachment is the bare minimum.
Holding law-breaking ICE agents legally accountable is the bare minimum.
ICE is beyond reform. Abolish it.
Backing Kristi Noem’s impeachment is the bare minimum.
Holding law-breaking ICE agents legally accountable is the bare minimum.
ICE is beyond reform. Abolish it.
January 25, 2026 at 9:59 PM
Voting NO on the DHS funding bill is the bare minimum.
Backing Kristi Noem’s impeachment is the bare minimum.
Holding law-breaking ICE agents legally accountable is the bare minimum.
ICE is beyond reform. Abolish it.
Backing Kristi Noem’s impeachment is the bare minimum.
Holding law-breaking ICE agents legally accountable is the bare minimum.
ICE is beyond reform. Abolish it.
Reposted by John Chodera
Dr. William Foege, a leader of one of humanity's greatest public health victories — the global eradication of smallpox — has died.
https://to.pbs.org/49WGkpV
https://to.pbs.org/49WGkpV
Leader in smallpox eradication, Dr. William Foege, dies at 89
Dr. William Foege, a leader of one of humanity's greatest public health victories — the global eradication of smallpox — has died.
www.pbs.org
January 25, 2026 at 9:17 PM
Dr. William Foege, a leader of one of humanity's greatest public health victories — the global eradication of smallpox — has died.
https://to.pbs.org/49WGkpV
https://to.pbs.org/49WGkpV
Reposted by John Chodera
Reposted by John Chodera
"Our agents can kill people on weekends, but you can't serve us 'til Monday."
Update: In the evidence preservation lawsuit, the current Civil Chief at the Minnesota U.S. Attorney's Office (who appears to be Ana Voss, based on the letter), refused to accept email service of the lawsuit last night and then refused to accept in-person service until Monday.
Ridiculous behavior.
Ridiculous behavior.
January 25, 2026 at 6:38 PM
"Our agents can kill people on weekends, but you can't serve us 'til Monday."
Reposted by John Chodera
One of the hardest things to do is bring campaign-level communications to the work of governance, and snowstorms are notoriously one of the biggest litmus tests that less-engaged voters use to judge mayoral administrations. This is an excellent way to communicate.
January 25, 2026 at 4:39 PM
One of the hardest things to do is bring campaign-level communications to the work of governance, and snowstorms are notoriously one of the biggest litmus tests that less-engaged voters use to judge mayoral administrations. This is an excellent way to communicate.
Reposted by John Chodera
I’m here for the positivity today. Tomorrow I want us to say to ourselves, “six guys brutally beat that man, shot him half a dozen times, and then lied about it on national television. they were probably prison guards, since that’s the population ICE recruits from. I wonder what goes on in prisons”
January 25, 2026 at 7:00 PM
I’m here for the positivity today. Tomorrow I want us to say to ourselves, “six guys brutally beat that man, shot him half a dozen times, and then lied about it on national television. they were probably prison guards, since that’s the population ICE recruits from. I wonder what goes on in prisons”
Reposted by John Chodera
It is insane and just impossible to fire 20% of NASAs senior engineering and management staff and axe its budget and at the same time, this year, drastically accelerate its Moon program.
the American government is effectively ending its space program.
Over 2,000 senior staff set to leave NASA under agency push
The losses could endanger the administration’s plans for landing astronauts on the moon and Mars.
www.politico.com
January 25, 2026 at 5:25 AM
It is insane and just impossible to fire 20% of NASAs senior engineering and management staff and axe its budget and at the same time, this year, drastically accelerate its Moon program.
Reposted by John Chodera
They are kidnapping young children and murdering citizens in the street in broad daylight and lying to us when we can see what they are doing. This will be in textbooks and generations from now will ask us what we stood for. 🖕🧊
January 25, 2026 at 5:28 AM
They are kidnapping young children and murdering citizens in the street in broad daylight and lying to us when we can see what they are doing. This will be in textbooks and generations from now will ask us what we stood for. 🖕🧊
Reposted by John Chodera
YouGov is out with a new poll after ICE killed another person in Minnesota today. Abolishing ICE is now +5 among all adults, and **+12 among independents**
substack.com/@gelliottmor...
substack.com/@gelliottmor...
January 25, 2026 at 2:10 AM
YouGov is out with a new poll after ICE killed another person in Minnesota today. Abolishing ICE is now +5 among all adults, and **+12 among independents**
substack.com/@gelliottmor...
substack.com/@gelliottmor...
Reposted by John Chodera
The violent attacks from federal enforcement in Minneapolis make it clear: we need a full abolition of ICE.
Our communities are hurting, especially immigrants. It’s up to us to use our voices and our power to protect them.
Our communities are hurting, especially immigrants. It’s up to us to use our voices and our power to protect them.
January 25, 2026 at 1:52 AM
The violent attacks from federal enforcement in Minneapolis make it clear: we need a full abolition of ICE.
Our communities are hurting, especially immigrants. It’s up to us to use our voices and our power to protect them.
Our communities are hurting, especially immigrants. It’s up to us to use our voices and our power to protect them.
Reposted by John Chodera
Reminder: If the Supreme Court upholds Trump’s attack on birthright citizenship, some of the ICE officers currently brutalizing Minnesotans may be reassigned to apprehend newborns from the hospital for immediate deportation. Just read the Trump administration’s own memo. slate.com/news-and-pol...
January 25, 2026 at 12:14 AM
Reminder: If the Supreme Court upholds Trump’s attack on birthright citizenship, some of the ICE officers currently brutalizing Minnesotans may be reassigned to apprehend newborns from the hospital for immediate deportation. Just read the Trump administration’s own memo. slate.com/news-and-pol...
Reposted by John Chodera
Some 2,255 measles cases were recorded last year, marking the highest point in over 30 years.
Measles Cases Boom To Start 2026—Here’s Where Cases Have Been Confirmed
Some 2,255 measles cases were recorded last year, marking the highest point in over 30 years.
www.forbes.com
January 23, 2026 at 8:35 PM
Some 2,255 measles cases were recorded last year, marking the highest point in over 30 years.
Reposted by John Chodera
A doctor who witnessed the shooting submits a sworn declaration in federal litigation to halt ICE surge in MN:
"I did not see him attack the agents or brandish a weapon of any kind."
and
"The victim had at least three bullet wounds in his back."
Read storage.courtlistener.com/recap/gov.us...
"I did not see him attack the agents or brandish a weapon of any kind."
and
"The victim had at least three bullet wounds in his back."
Read storage.courtlistener.com/recap/gov.us...
January 25, 2026 at 1:49 AM
A doctor who witnessed the shooting submits a sworn declaration in federal litigation to halt ICE surge in MN:
"I did not see him attack the agents or brandish a weapon of any kind."
and
"The victim had at least three bullet wounds in his back."
Read storage.courtlistener.com/recap/gov.us...
"I did not see him attack the agents or brandish a weapon of any kind."
and
"The victim had at least three bullet wounds in his back."
Read storage.courtlistener.com/recap/gov.us...
Reposted by John Chodera
I don’t want to hear anything from an elected official unless it’s a plan to defund the DHS and impeach Noem, Bovino, etc. No texts. No emails. No talk about the economy. Step up or step off.
January 24, 2026 at 7:23 PM
I don’t want to hear anything from an elected official unless it’s a plan to defund the DHS and impeach Noem, Bovino, etc. No texts. No emails. No talk about the economy. Step up or step off.
Reposted by John Chodera
After hearing today’s news & knowing Alex Pretti - dry January is over.
In my ICU rotations at Minneapolis VA, nights in residency, & days as a fellow in infectious diseases, I worked alongside Alex.
Surely our nurses unions can help make some good trouble for a fallen hero?
#Neat
#NoICE
#MedSky
In my ICU rotations at Minneapolis VA, nights in residency, & days as a fellow in infectious diseases, I worked alongside Alex.
Surely our nurses unions can help make some good trouble for a fallen hero?
#Neat
#NoICE
#MedSky
January 25, 2026 at 1:47 AM
Reposted by John Chodera
Imagine what’s happening in the camps.
Imagine how much they’d be lying about what happened without all the videos showing it from multiple angles.
January 24, 2026 at 11:29 PM
Imagine what’s happening in the camps.
Reposted by John Chodera
This looks like an execution. There must be an investigation. There must be accountability.
Joining ICE does not give you license to murder.
The President is escalating the situation—and I have no faith he will stop. The Republican Congress must join us to end this. Enough.
Joining ICE does not give you license to murder.
The President is escalating the situation—and I have no faith he will stop. The Republican Congress must join us to end this. Enough.
Live: Man shot and killed by federal agents in Minneapolis this morning, police chief says
A video appears to shows federal agents wrestling a man to the ground then shooting him. The Department of Homeland Security said the man was armed with a gun.
www.startribune.com
January 24, 2026 at 5:58 PM
This looks like an execution. There must be an investigation. There must be accountability.
Joining ICE does not give you license to murder.
The President is escalating the situation—and I have no faith he will stop. The Republican Congress must join us to end this. Enough.
Joining ICE does not give you license to murder.
The President is escalating the situation—and I have no faith he will stop. The Republican Congress must join us to end this. Enough.
Reposted by John Chodera
This is essentially what governments did in the late 1900s and early 2000s with respect to Nazis. Whether you were a lowly concentration camp guard or in Hitler's inner circle, if there was evidence you were a Nazi, it was straight to jail with your walker.
It worked.
It worked.
Maybe instead of identifying specific ICE agents who do particularly heinous things, we could just penalize everyone who was on payroll at the agency starting by a certain date.
January 24, 2026 at 3:49 AM
This is essentially what governments did in the late 1900s and early 2000s with respect to Nazis. Whether you were a lowly concentration camp guard or in Hitler's inner circle, if there was evidence you were a Nazi, it was straight to jail with your walker.
It worked.
It worked.
Reposted by John Chodera
Alex Pretti was a colleague at the VA. We hired him to recruit for our trial. He became an ICU nurse- I lover working with him. He was a good kind person who lived to help and these fuckers executed him.
White. Hot. Rage.
White. Hot. Rage.
January 24, 2026 at 7:31 PM
Alex Pretti was a colleague at the VA. We hired him to recruit for our trial. He became an ICU nurse- I lover working with him. He was a good kind person who lived to help and these fuckers executed him.
White. Hot. Rage.
White. Hot. Rage.
Reposted by John Chodera
It's time to abolish Trump’s ICE.
January 24, 2026 at 7:26 PM
It's time to abolish Trump’s ICE.
Reposted by John Chodera
Reporters, if you wrote about learning loss due to covid school closures, you can write about learning loss due to state terror.
I am not being snarky. I need my colleagues who wrote on covid school lockdowns to engage with this. To be as loud as they have been about prior "learning loss." Hell, you can cite Tom & Mark's AERJ paper so you feel better that there's some econ somewhere in your argument.
"In St. Paul, at least one-fourth of students from Spanish-speaking homes have missed every day of school since Dec. 12."
January 23, 2026 at 11:06 PM
Reporters, if you wrote about learning loss due to covid school closures, you can write about learning loss due to state terror.
Reposted by John Chodera
If you / your lab / your institution rely on NIH funding, you need to read this and understand how this is one of many changes affecting you. www.nature.com/articles/d41...
Exclusive: key NIH review panels due to lose all members by the end of 2026
Thirteen of the agency’s advisory councils, which must review grant applications before funding is awarded, are on track to have no voting members.
www.nature.com
January 23, 2026 at 1:44 PM
If you / your lab / your institution rely on NIH funding, you need to read this and understand how this is one of many changes affecting you. www.nature.com/articles/d41...
Reposted by John Chodera
Please know that if your institution did this, it's a racist institution. Sure, many good people still work there and do good work there. But the school as a whole functions as a white supremacist institution. Proceed accordingly.
This must be weird news to see if you’re one of the literally hundreds or even thousands of university administrators who preemptively censored faculty, scrubbed websites, changed the names of centers, etc.
Trump administration drops legal appeal over anti-DEI funding threat to schools and colleges. This leaves in place a federal judge's ruling that the anti-DEI effort violated the First Amendment and federal procedural rules. (Via AP) apnews.com/article/dei-... #ncpol #nced
January 23, 2026 at 3:41 PM
Please know that if your institution did this, it's a racist institution. Sure, many good people still work there and do good work there. But the school as a whole functions as a white supremacist institution. Proceed accordingly.
Reposted by John Chodera
📣 Please spread: we’re hiring a Lab Manager! It is a critical position in our new lab. As our lab moves to Barcelona and joins the @crg.eu, we’re looking for a Lab Manager to help build the lab and set the lab atmosphere.
🔗 Apply here 👉 recruitment.crg.eu/content/jobs...
🔗 Apply here 👉 recruitment.crg.eu/content/jobs...
January 23, 2026 at 6:41 AM
📣 Please spread: we’re hiring a Lab Manager! It is a critical position in our new lab. As our lab moves to Barcelona and joins the @crg.eu, we’re looking for a Lab Manager to help build the lab and set the lab atmosphere.
🔗 Apply here 👉 recruitment.crg.eu/content/jobs...
🔗 Apply here 👉 recruitment.crg.eu/content/jobs...