Drugs for Neglected Diseases initiative (DNDi)
@dndi.org
International non-profit developing safe, effective, and affordable treatments for the most neglected patients.
To learn about the global burden of cryptococcal disease, limitations of currently available treatments, attributes of much-needed novel treatments, and potential drug discovery and development pathways, click here www.journalofinfection.com/article/S016...
Target product profile and discovery and development path for novel cryptococcal disease treatments
Cryptococcus neoformans and Cryptococcus gattii are World Health Organization critical
and medium priority pathogens, respectively. These mainly impact people with human
immunodeficiency virus residin...
www.journalofinfection.com
December 19, 2025 at 2:49 PM
To learn about the global burden of cryptococcal disease, limitations of currently available treatments, attributes of much-needed novel treatments, and potential drug discovery and development pathways, click here www.journalofinfection.com/article/S016...
How does treatment for #PKDL affect the #leishmaniasis parasite and the human immune system? We need to know so that we can get the dosing right. Read more here doi.org/10.1002/cpt....
Bidirectional Interaction Between Liposomal Amphotericin B Pharmacokinetics and Parasite Dynamics in Patients With Post‐Kala‐Azar Dermal Leishmaniasis: Potential Implications for Optimal Dosing
Post-kala-azar dermal leishmaniasis (PKDL) involves a high macrophage burden in which the Leishmania parasites reside. Liposomal amphotericin B (LAmB) plays a key role in the treatment of PKDL. The m...
doi.org
December 19, 2025 at 2:26 PM
How does treatment for #PKDL affect the #leishmaniasis parasite and the human immune system? We need to know so that we can get the dosing right. Read more here doi.org/10.1002/cpt....
✨We wish you a joyful holiday season & happy 2026! We deeply appreciate the colleagues, supporters, partners, & friends who have joined us in our journey putting equity at the heart of medical innovation.
We look forward to continuing to innovate together in the year to come!
We look forward to continuing to innovate together in the year to come!
December 19, 2025 at 11:22 AM
✨We wish you a joyful holiday season & happy 2026! We deeply appreciate the colleagues, supporters, partners, & friends who have joined us in our journey putting equity at the heart of medical innovation.
We look forward to continuing to innovate together in the year to come!
We look forward to continuing to innovate together in the year to come!
On his motorcycle, Andrew Ochieng reaches remote communities on the Kenya–Uganda border to diagnose visceral leishmaniasis and refer people to treatment.
Kang-Chun Cheng met villagers, patients and researchers, and tells their stories for BBC 👇
www.bbc.com/future/artic...
Kang-Chun Cheng met villagers, patients and researchers, and tells their stories for BBC 👇
www.bbc.com/future/artic...
The motorcyclist fighting a deadly disease in the African bush
As a child Andrew Ochieng survived the world's second deadliest parasite. Today he is working to stop this little-known killer from the back of a motorbike.
www.bbc.com
December 18, 2025 at 1:47 PM
On his motorcycle, Andrew Ochieng reaches remote communities on the Kenya–Uganda border to diagnose visceral leishmaniasis and refer people to treatment.
Kang-Chun Cheng met villagers, patients and researchers, and tells their stories for BBC 👇
www.bbc.com/future/artic...
Kang-Chun Cheng met villagers, patients and researchers, and tells their stories for BBC 👇
www.bbc.com/future/artic...
An individual participant data platform at #IDDO hosts data from nearly 15,000 patients with #leishmaniasis; this can enable new evidence generation and serve as historical data to support accelerated drug development. Read more at doi.org/10.1186/s130... @BioMedCentral
The development of a global research agenda and individual participant data platform for visceral leishmaniasis: challenges and future opportunities - Parasites & Vectors
Background Visceral leishmaniasis (VL) is one of the neglected tropical diseases (NTDs) listed by the World Health Organization (WHO). The disease is currently in the elimination phase in the Indian s...
doi.org
December 18, 2025 at 1:16 PM
An individual participant data platform at #IDDO hosts data from nearly 15,000 patients with #leishmaniasis; this can enable new evidence generation and serve as historical data to support accelerated drug development. Read more at doi.org/10.1186/s130... @BioMedCentral
We’re pleased to introduce the 2025-2026 cohort of the #WithoutBordersMediaFellowship! This year, the fellows will spotlight #NTDs & gender-responsive R&D, along with the systemic barriers shaping health outcomes in #SouthAsia.
tinyurl.com/3x74zku3 @gardp.bsky.social
#beatNTDs
tinyurl.com/3x74zku3 @gardp.bsky.social
#beatNTDs
December 16, 2025 at 2:31 PM
We’re pleased to introduce the 2025-2026 cohort of the #WithoutBordersMediaFellowship! This year, the fellows will spotlight #NTDs & gender-responsive R&D, along with the systemic barriers shaping health outcomes in #SouthAsia.
tinyurl.com/3x74zku3 @gardp.bsky.social
#beatNTDs
tinyurl.com/3x74zku3 @gardp.bsky.social
#beatNTDs
👏 Congratulations @gardp.bsky.social on this major achievement—a real breakthrough for patients and an important win in the fight against antimicrobial resistance!
We’re especially delighted to see this achievement given our shared history and our joint CMC platform.
#Gonorrhoea #AMR
We’re especially delighted to see this achievement given our shared history and our joint CMC platform.
#Gonorrhoea #AMR
🚨 US FDA approves Nuzolvence® (zoliflodacin), a first-in-class oral antibiotic for uncomplicated urogenital gonorrhoea, co-developed by GARDP & Innoviva Specialty Therapeutics.
Zoliflodacin is the first new treatment to be developed solely for gonorrhoea in decades.
🔗 gardp.org/nuzolvence-z...
Zoliflodacin is the first new treatment to be developed solely for gonorrhoea in decades.
🔗 gardp.org/nuzolvence-z...
December 15, 2025 at 10:43 AM
👏 Congratulations @gardp.bsky.social on this major achievement—a real breakthrough for patients and an important win in the fight against antimicrobial resistance!
We’re especially delighted to see this achievement given our shared history and our joint CMC platform.
#Gonorrhoea #AMR
We’re especially delighted to see this achievement given our shared history and our joint CMC platform.
#Gonorrhoea #AMR
Congratulations to Nurse Luke Kanyang'areng on his nomination to the list of #Top100Kenyans2025.
A well-deserved recognition for his work as a patient advocate, champion for neglected populations in Kenya & reinforcing primary healthcare delivery.
Read more ➡️ www.kenyans.co.ke/personality/...
A well-deserved recognition for his work as a patient advocate, champion for neglected populations in Kenya & reinforcing primary healthcare delivery.
Read more ➡️ www.kenyans.co.ke/personality/...
December 9, 2025 at 3:58 PM
Congratulations to Nurse Luke Kanyang'areng on his nomination to the list of #Top100Kenyans2025.
A well-deserved recognition for his work as a patient advocate, champion for neglected populations in Kenya & reinforcing primary healthcare delivery.
Read more ➡️ www.kenyans.co.ke/personality/...
A well-deserved recognition for his work as a patient advocate, champion for neglected populations in Kenya & reinforcing primary healthcare delivery.
Read more ➡️ www.kenyans.co.ke/personality/...
Dengue outbreaks in Cuba (where 33 people died in recent months) and Bangladesh (394 deaths this year).
The disease is fueled by climate change and globalization. Cases are almost doubling each year since 2021. There is still no specific treatment.
www.bssnews.net/news/338636
The disease is fueled by climate change and globalization. Cases are almost doubling each year since 2021. There is still no specific treatment.
www.bssnews.net/news/338636
Three dengue patients die, 565 fresh cases detected overnight | News
DHAKA, Dec 04, 2025 (BSS) - Health officials today said they recorded 565 fresh cases of dengue onslaughts, killing at
www.bssnews.net
December 4, 2025 at 3:18 PM
Dengue outbreaks in Cuba (where 33 people died in recent months) and Bangladesh (394 deaths this year).
The disease is fueled by climate change and globalization. Cases are almost doubling each year since 2021. There is still no specific treatment.
www.bssnews.net/news/338636
The disease is fueled by climate change and globalization. Cases are almost doubling each year since 2021. There is still no specific treatment.
www.bssnews.net/news/338636
We are pleased to welcome 5 new members to DNDi’s Board of Directors. Their leadership, expertise, and long-standing commitment to global health will help strengthen our unique collaborations with our founding partners & further embed patient engagement at the heart of our work.
December 4, 2025 at 10:39 AM
We are pleased to welcome 5 new members to DNDi’s Board of Directors. Their leadership, expertise, and long-standing commitment to global health will help strengthen our unique collaborations with our founding partners & further embed patient engagement at the heart of our work.
📖 We spoke with Dr Markus Fraundorfer about his new independent study on the impact of our collaborative, not-for-profit drug development model. In this video, he shares his motivation for the book, key insights, and why the topic matters for global health today.
www.youtube.com/shorts/x3CG_...
www.youtube.com/shorts/x3CG_...
Book Chat with Dr Markus Fraundorfer
YouTube video by Drugs for Neglected Diseases initiative (DNDi)
www.youtube.com
December 3, 2025 at 12:12 PM
📖 We spoke with Dr Markus Fraundorfer about his new independent study on the impact of our collaborative, not-for-profit drug development model. In this video, he shares his motivation for the book, key insights, and why the topic matters for global health today.
www.youtube.com/shorts/x3CG_...
www.youtube.com/shorts/x3CG_...
Results from a Phase II clinical trial of a promising dengue antiviral developed by Johnson & Johnson have been published by @nejm.org. The findings are promising, but further development is needed.
There is still no specific treatment for #dengue.
www.science.org/content/arti...
There is still no specific treatment for #dengue.
www.science.org/content/arti...
Antiviral drug abandoned by pharma shows promise against dengue
A daily pill can prevent the crippling disease, but its maker won’t bring it to market
www.science.org
December 2, 2025 at 4:54 PM
Results from a Phase II clinical trial of a promising dengue antiviral developed by Johnson & Johnson have been published by @nejm.org. The findings are promising, but further development is needed.
There is still no specific treatment for #dengue.
www.science.org/content/arti...
There is still no specific treatment for #dengue.
www.science.org/content/arti...
'It feels as if the disease is eating me from the inside.' In Turkana, Kenya, @efe.com shares harrowing stories of people with mycetoma, a neglected disease that empoverishes communities. 'I dont know how I'll pay school fees for my five children'. www.swissinfo.ch/spa/%22como-...
"Como si me comiera desde dentro": la enfermedad que ataca los huesos en el norte de Kenia
Lucía Blanco Gracia
www.swissinfo.ch
December 2, 2025 at 12:18 PM
'It feels as if the disease is eating me from the inside.' In Turkana, Kenya, @efe.com shares harrowing stories of people with mycetoma, a neglected disease that empoverishes communities. 'I dont know how I'll pay school fees for my five children'. www.swissinfo.ch/spa/%22como-...
Reposted by Drugs for Neglected Diseases initiative (DNDi)
#Leishmaniasis is an endemic disease caused by Leishmania parasites and transmitted through the bite of female sand flies https://www.nature.c...
November 26, 2025 at 7:09 PM
#Leishmaniasis is an endemic disease caused by Leishmania parasites and transmitted through the bite of female sand flies https://www.nature.c...
Important news for #dengue today! We congratulate the Instituto Butantan in Brazil for the approval today of its single-dose dengue vaccine by the Brazilian regulatory authority ANVISA. Our take by @andre-siqueira.bsky.social #Treatment4Dengue #dengue
November 26, 2025 at 5:48 PM
Important news for #dengue today! We congratulate the Instituto Butantan in Brazil for the approval today of its single-dose dengue vaccine by the Brazilian regulatory authority ANVISA. Our take by @andre-siqueira.bsky.social #Treatment4Dengue #dengue
Independent journalist Mansi Vijay, a 2024 MSF South Asia–DNDi Media Fellow, has been honoured with the Laadli Media Award for Gender Sensitivity for her story on how women confront #LymphaticFilariasis & the stigma, silence & barriers around it.
📰 tinyurl.com/4856udhc
#Journalism @msf.ca
📰 tinyurl.com/4856udhc
#Journalism @msf.ca
How Women in UP Confront A Neglected Disease–And Stigma
Of the 345 districts in India affected by lymphatic filariasis, 51 are in Uttar Pradesh where women are at the frontlines, confronting their suffering and a long-standing public health crisis
tinyurl.com
November 26, 2025 at 10:08 AM
Independent journalist Mansi Vijay, a 2024 MSF South Asia–DNDi Media Fellow, has been honoured with the Laadli Media Award for Gender Sensitivity for her story on how women confront #LymphaticFilariasis & the stigma, silence & barriers around it.
📰 tinyurl.com/4856udhc
#Journalism @msf.ca
📰 tinyurl.com/4856udhc
#Journalism @msf.ca
‘Any organization that works in R&D has a duty to have proper governance that includes peer review.’
📽️ Watch our conversation with Dr Pauline Williams, our new Scientific Advisory Committee chair: youtube.com/watch?v=m4TC...
👏 Welcome to the role!
📽️ Watch our conversation with Dr Pauline Williams, our new Scientific Advisory Committee chair: youtube.com/watch?v=m4TC...
👏 Welcome to the role!
Interview with Dr Pauline Williams, new DNDi Scientific Advisory Committee (SAC) Chair
YouTube video by Drugs for Neglected Diseases initiative (DNDi)
youtube.com
November 24, 2025 at 2:01 PM
‘Any organization that works in R&D has a duty to have proper governance that includes peer review.’
📽️ Watch our conversation with Dr Pauline Williams, our new Scientific Advisory Committee chair: youtube.com/watch?v=m4TC...
👏 Welcome to the role!
📽️ Watch our conversation with Dr Pauline Williams, our new Scientific Advisory Committee chair: youtube.com/watch?v=m4TC...
👏 Welcome to the role!
Carolina Batista, our Latin America Board President, grew up with Amazonian roots, worked closely with Indigenous communities, and now leads in global health. Here’s her message to #COP30⤵️
youtube.com/shorts/cNoWL...
youtube.com/shorts/cNoWL...
What she learned from Indigenous communities could change how we talk about climate
YouTube video by Drugs for Neglected Diseases initiative (DNDi)
youtube.com
November 21, 2025 at 3:38 PM
Carolina Batista, our Latin America Board President, grew up with Amazonian roots, worked closely with Indigenous communities, and now leads in global health. Here’s her message to #COP30⤵️
youtube.com/shorts/cNoWL...
youtube.com/shorts/cNoWL...
Our Policy Advocacy Director @childsmichelle.bsky.social with an extremely timely opinion piece in the @financialtimes.com! How to ensure that the exodus from infectious disease research does not affect millions around the world in need of innovation.
Neglecting infectious diseases is a market failure on.ft.com/48r3i8U | opinion
Neglecting infectious diseases is a market failure
Major companies are reducing research on new medicines for illnesses that affect billions of people
on.ft.com
November 20, 2025 at 6:10 PM
Our Policy Advocacy Director @childsmichelle.bsky.social with an extremely timely opinion piece in the @financialtimes.com! How to ensure that the exodus from infectious disease research does not affect millions around the world in need of innovation.
Beni survived #SleepingSickness thanks to timely diagnosis & innovative oral treatments.
This #WorldChildrensDay we call for support to develop urgently needed life-saving treatments for children like Beni living with NTDs.
Watch his story in our new film www.youtube.com/watch?v=GcIx...
This #WorldChildrensDay we call for support to develop urgently needed life-saving treatments for children like Beni living with NTDs.
Watch his story in our new film www.youtube.com/watch?v=GcIx...
Beni: Surviving Sleeping Sickness
YouTube video by Drugs for Neglected Diseases initiative (DNDi)
www.youtube.com
November 20, 2025 at 9:56 AM
Beni survived #SleepingSickness thanks to timely diagnosis & innovative oral treatments.
This #WorldChildrensDay we call for support to develop urgently needed life-saving treatments for children like Beni living with NTDs.
Watch his story in our new film www.youtube.com/watch?v=GcIx...
This #WorldChildrensDay we call for support to develop urgently needed life-saving treatments for children like Beni living with NTDs.
Watch his story in our new film www.youtube.com/watch?v=GcIx...
👋 We welcome Sanjay Sarin as our new Continental Lead Asia and South Asia Director.
A global health leader with 20+ years’ experience, he brings deep expertise in strategy, partnerships, & access, & will help strengthen our work across Asia & expand patient-centred innovation in the region.
A global health leader with 20+ years’ experience, he brings deep expertise in strategy, partnerships, & access, & will help strengthen our work across Asia & expand patient-centred innovation in the region.
November 18, 2025 at 4:06 PM
👋 We welcome Sanjay Sarin as our new Continental Lead Asia and South Asia Director.
A global health leader with 20+ years’ experience, he brings deep expertise in strategy, partnerships, & access, & will help strengthen our work across Asia & expand patient-centred innovation in the region.
A global health leader with 20+ years’ experience, he brings deep expertise in strategy, partnerships, & access, & will help strengthen our work across Asia & expand patient-centred innovation in the region.
💻 We recently hosted a webinar on bridging the research-to-policy gap for NTDs together with @aphrc.bsky.social.
👉 Eliminating NTDs isn't just a scientific challenge; it's a governance and policy challenge which requires Africa-led domestic financing solutions.
www.youtube.com/watch?v=2YXo...
👉 Eliminating NTDs isn't just a scientific challenge; it's a governance and policy challenge which requires Africa-led domestic financing solutions.
www.youtube.com/watch?v=2YXo...
Webinar: Bridging the gap between research and policy for NTDs amid a changing funding landscape
YouTube video by Drugs for Neglected Diseases initiative (DNDi)
www.youtube.com
November 18, 2025 at 2:24 PM
💻 We recently hosted a webinar on bridging the research-to-policy gap for NTDs together with @aphrc.bsky.social.
👉 Eliminating NTDs isn't just a scientific challenge; it's a governance and policy challenge which requires Africa-led domestic financing solutions.
www.youtube.com/watch?v=2YXo...
👉 Eliminating NTDs isn't just a scientific challenge; it's a governance and policy challenge which requires Africa-led domestic financing solutions.
www.youtube.com/watch?v=2YXo...
JUST RELEASED: Open science in a closed world 🌍📘Our new policy report shows how open, collaborative science and pro-access IP approaches can accelerate medical innovation & equitable access to health tools for all. #MakeScienceOpen youtube.com/shorts/UmBAr...
Open Science in a Closed World
YouTube video by Drugs for Neglected Diseases initiative (DNDi)
youtube.com
November 17, 2025 at 11:05 AM
JUST RELEASED: Open science in a closed world 🌍📘Our new policy report shows how open, collaborative science and pro-access IP approaches can accelerate medical innovation & equitable access to health tools for all. #MakeScienceOpen youtube.com/shorts/UmBAr...
Congratulations to Prof Shyam Sundar, on receiving the Clara Southmayd Ludlow Medal from @astmh.bsky.social for his exemplary contributions to visceral leishmaniasis research & innovation. We’re proud to have collaborated with him to advance better, safer & accessible treatments for NTDs.
November 13, 2025 at 4:10 PM
Congratulations to Prof Shyam Sundar, on receiving the Clara Southmayd Ludlow Medal from @astmh.bsky.social for his exemplary contributions to visceral leishmaniasis research & innovation. We’re proud to have collaborated with him to advance better, safer & accessible treatments for NTDs.