YouTube video by Francis Crick Institute

Outer membrane attachment to peptidoglycan enables periplasmic pressure to build up and counter cytoplasmic turgor pressure, preventing lysis during osmotic challenges in Escherichia coli.

Background: Antimicrobial resistance (AMR) in bacterial pathogens is a major threat to global health, rendering standard treatments ineffective and increasing the risk of severe infection or death. Re...

Tuberculosis (TB) remains one of the world’s leading infectious diseases. Every year on March 24th, World Tuberculosis Day is observed, which in 1882 is when Robert Koch announced the discovery of Mycobacterium tuberculosis (Mtb) as the causative agent of TB. This Special Issue features 30 original research articles, perspectives, and reviews from researchers representing 11 countries across all six major continents. ACS Infectious Diseases hopes this special issue encourages our readers to explore the wide range of research showcasing advances in drug discovery and a greater understanding of TB biology.

Rashan, Bartlett and colleagues show that mammalian 4-hydroxy fatty acids are primarily catabolized by ACAD10 and ACAD11 (atypical mitochondrial and peroxisomal acyl-CoA dehydrogenases, respectively) ...

Cyclodipeptide oxidases are filamentous enzymes. Here, the authors dissect the mechanism of a promiscuous flavoenzyme from the biosynthesis of cyclodipeptide natural products, unveiling fast catalysis...

The underlying factors that lead to specific strains within a species to emerge as human pathogens remain mostly enigmatic. The diarrheal disease c...

Partitioning of FtsN and the septal peptidoglycan synthesis complex between an active synthesis track and an inactive denuded glycan track coordinates opposing peptidoglycan synthesis and degradation ...

Job Title: Associate or Senior Editor Nature Metabolism Location: New York or Shanghai Application Deadline: June 10th, 2025 About Springer Nature Group Springer Nature opens the doors to discovery for researchers, educators, clinicians and other professionals. Every day, around the globe, our imprints, books, journals, platforms and technology solutions reach millions of people. For over 180 years our brands and imprints have been a trusted source of knowledge to these communities and today, more than ever, we see it as our responsibility to ensure that fundamental knowledge can be found, verified, understood and used by our communities – enabling them to improve outcomes, make progress, and benefit the generations that follow. Visit http://group.springernature.com/ and follow @SpringerNature / @SpringerNatureGroup. About the Brand Nature Portfolio is a flagship portfolio of journals, products and services including Nature and the Nature-branded journals, dedicated to serving the scientific community. Visit nature.com and follow @Nature / @NaturePortfolio. About the Role Nature Metabolism seeks an Associate or Senior Editor to join our expanding editorial team. Do you love science but feel that a research career isn’t enough to sate your desire to learn more about the natural world? Do you enjoy reading papers outside your chosen area of research? If the answer is ‘yes’ to any or both questions, you could be the person we’re looking for to join the editorial team of Nature Metabolism. This role can be in our New York or Shanghai offices on a hybrid working model. Role Responsibilities: Working closely with other editors on all aspects of the editorial process, including manuscript selection and overseeing peer review. 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Experience in cancer research or immunology is a plus. Excellent interpersonal, communication and organizational skills Fluent in spoken and written English To Apply: Please submit a cover letter explaining your interest in the position and your salary expectations please submit a CV concise (up to 500 words) discussion of recent developments or trends in the wider metabolism field, which you have found particularly exciting (and explaining why). 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A brand-new WHO leadership team has been announced, including not only a dramatically reduced number of  leaders but a major shake-out of longstanding faces

In this study, we investigated how iron limitation alters central metabolism in Mycobacterium tuberculosis using metabolomics and stable isotope tracing. Our findings reveal a well-orchestrated metabo...

Fungi can keep us healthy or cause disease. As climate change drives fungi to adapt, learn how we can harness the benefits and tackle the threats.

Genomic and functional analyses of healthcare-associated vancomycin-resistant Enterococcus faecium reveal that bacteriocin T8 is enriched in emergent lineages and provides a competitive advantage in v...

Mandimycin, a polyene macrolide, exhibits strong antifungal activity and possesses a mode of action that is distinct from other compounds of this class.