Richard Lenski traces the legacy of Escherichia coli and how science is evolving to use this model organism in new ways.

Studies focused on bacterial diversity in rivers often face significant limitations. Traditional sampling approaches frequently overlook spatial and temporal variability at the reach scale. Molecular ...

Nature Microbiology - Candida auris can scavenge carbon dioxide from microenvironments through Nce103 to sustain fitness when colonizing human skin.

Abstract. Accelerating climate change and extreme temperatures urge us to better understand the potential of populations to tolerate and adapt to thermal c

Background Septoria tritici blotch, caused by Zymoseptoria tritici, is a major wheat disease worldwide. Demethylation inhibitor (DMI) fungicides, which target the sterol 14α-demethylase enzyme encoded...

Features identified as important predictors of IMI case status using machine learning methods deviated from classic IMI risk factors. Our results will inform robust and feasible IMI case prediction models for public health surveillance.

For most species in nature, transcriptome data is much more readily available than genome data. Without a reference genome, however, gene calling is cumbersome and inaccurate due to the high degree…

Features identified as important predictors of IMI case status using machine learning methods deviated from classic IMI risk factors. Our results will inform robust and feasible IMI case prediction models for public health surveillance.

Machine learning methods have emerged as promising tools to predict antimicrobial resistance (AMR) and uncover resistance determinants from genomic data. This study shows that sampling biases driven b...

Termites detect and selectively respond to the presence of weedy fungi, and burying behavior is more pronounced in the presence of Termitomyces (crop fungi), suggesting a context-dependent perception...

A genomic analysis shows that the evolution of genome size and gene content among fungal pathogens in the class Sordariomycetes varies depending on their interactions with hosts and vectors.

Peer review has been the cornerstone of scientific inquiry for centuries and is considered the backbone of scientific quality and rigour (Spier, 2002). Des

<span><i>Ralstonia mannitolilytica</i> is a rare emerging, multidrug-resistant, opportunistic pathogen known to cause nosocomial outbreaks associated with hospital water sources and medical devices. In June 2024, the microbiology laboratory of Lausanne University Hospital alerted the Infection Prevention</span> …

SUMMARYInvasive fungal infections affect approximately 6.5 million people every year. These infections are frequently associated with high mortality rates, often exceeding 50%, even with antifungal therapy. Candida auris is a multidrug-resistant fungal pathogen that has a unique ability to grow and persist on human skin. Long-term skin colonization by C. auris is a significant medical concern because colonized patients may facilitate inter- and intra-hospital transmission of C. auris to other patients. Furthermore, C. auris-colonized patients are at risk of developing more serious systemic infections. The diagnosis of C. auris infections is often hampered by misidentification, leading to delays in starting appropriate antifungal therapy. Here, we summarize the global burden of candidiasis due to C. auris, antifungal drug resistance mechanisms, host and fungal factors affecting skin colonization, current diagnostic approaches, as well as current and future challenges to combat the spread of invasive fungal infections.

Adaptation occurs through the selection of beneficial mutations enhancing fitness in a specific environment. However, since environments vary across time and space, mutations that are positively selec...

Mushroom-forming fungi have along evolutionary history and a suite of important ecological roles. This Review highlights advances in understanding of Agaricomycetes evolution and ecology driven by gen...

Thrush is one of the most common infections in the world.