Clement Tsui PhD 🇭🇰 🇨🇦
@clementsui.bsky.social
- Prin Scientific Officer, NCID, Singapore
- Asst Prof @UBC Canada
- Asst Prof @NTU Singapore
- views are my own
- Editor, tea lover, hiker
#microbiology #mycology #evolutionarybiology #genomics #AMR
- Asst Prof @UBC Canada
- Asst Prof @NTU Singapore
- views are my own
- Editor, tea lover, hiker
#microbiology #mycology #evolutionarybiology #genomics #AMR
Reposted by Clement Tsui PhD 🇭🇰 🇨🇦
Exciting news! I have two positions open in my lab at the UoManchester: one PDRA and one Research Tech.
Join our team to study evolutionary mycology and help us understand antifungal resistance in fungal pathogens. A fantastic opportunity to join the brilliant Manchester Fungal Infection Group!
Join our team to study evolutionary mycology and help us understand antifungal resistance in fungal pathogens. A fantastic opportunity to join the brilliant Manchester Fungal Infection Group!
November 5, 2025 at 3:35 PM
Exciting news! I have two positions open in my lab at the UoManchester: one PDRA and one Research Tech.
Join our team to study evolutionary mycology and help us understand antifungal resistance in fungal pathogens. A fantastic opportunity to join the brilliant Manchester Fungal Infection Group!
Join our team to study evolutionary mycology and help us understand antifungal resistance in fungal pathogens. A fantastic opportunity to join the brilliant Manchester Fungal Infection Group!
Reposted by Clement Tsui PhD 🇭🇰 🇨🇦
Still using 16S/ITS profiling? You might want to reconsider👀
Our new paper presents pangenome-informed amplicons that provide up to 10× higher phylogenetic resolution than full-length ribosomal markers- while remaining cost effective and scalable!
microbiomejournal.biomedcentral.com/articles/10....
Our new paper presents pangenome-informed amplicons that provide up to 10× higher phylogenetic resolution than full-length ribosomal markers- while remaining cost effective and scalable!
microbiomejournal.biomedcentral.com/articles/10....
High-resolution profiling of bacterial and fungal communities using pangenome-informed taxon-specific long-read amplicons - Microbiome
Background High-throughput sequencing technologies have greatly advanced our understanding of microbiomes, but resolving microbial communities at species and strain levels remains challenging. Results...
microbiomejournal.biomedcentral.com
October 30, 2025 at 1:32 PM
Still using 16S/ITS profiling? You might want to reconsider👀
Our new paper presents pangenome-informed amplicons that provide up to 10× higher phylogenetic resolution than full-length ribosomal markers- while remaining cost effective and scalable!
microbiomejournal.biomedcentral.com/articles/10....
Our new paper presents pangenome-informed amplicons that provide up to 10× higher phylogenetic resolution than full-length ribosomal markers- while remaining cost effective and scalable!
microbiomejournal.biomedcentral.com/articles/10....
Discarded cigarette butts as overlooked reservoirs and amplifiers of antibiotic resistance genes and pathogens in urban green spaces | PNAS www.pnas.org/doi/abs/10.1...
Discarded cigarette butts as overlooked reservoirs and amplifiers of antibiotic resistance genes and pathogens in urban green spaces | PNAS
Cigarette butts are widely discarded in urban green spaces, yet their microbial health
risks remain poorly understood. In a nationwide survey acros...
www.pnas.org
October 30, 2025 at 4:42 AM
Discarded cigarette butts as overlooked reservoirs and amplifiers of antibiotic resistance genes and pathogens in urban green spaces | PNAS www.pnas.org/doi/abs/10.1...
Antifungal treatment strategies and their impact on resistance development in clinical settings url: academic.oup.com/jac/article/...
Antifungal treatment strategies and their impact on resistance development in clinical settings
Abstract. Invasive fungal diseases, particularly among immunocompromised patients, represent a growing clinical challenge due to limited therapeutic option
academic.oup.com
October 27, 2025 at 1:15 PM
Antifungal treatment strategies and their impact on resistance development in clinical settings url: academic.oup.com/jac/article/...
Escherichia coli with a 57-codon genetic code | Science www.science.org/doi/10.1126/...
Escherichia coli with a 57-codon genetic code
The near-universal genetic code uses 64 codons to encode the 20 canonical amino acids and protein synthesis. Here, we designed and generated Escherichia coli with a 4-megabase synthetic genome in whic...
www.science.org
October 26, 2025 at 1:18 AM
Escherichia coli with a 57-codon genetic code | Science www.science.org/doi/10.1126/...
Reposted by Clement Tsui PhD 🇭🇰 🇨🇦
Identification and Domestication of a Wild Edible Oyster Mushroom Growing on Loblolly Pine (Pinus taeda) in Mississippi https://www.biorxiv.org/content/10.1101/2025.10.23.684254v1
October 25, 2025 at 1:31 AM
Identification and Domestication of a Wild Edible Oyster Mushroom Growing on Loblolly Pine (Pinus taeda) in Mississippi https://www.biorxiv.org/content/10.1101/2025.10.23.684254v1
Reposted by Clement Tsui PhD 🇭🇰 🇨🇦
Wheat and barley stripe rust pan-genome facilitates discovery of the predominant North American lineage's origin in somatic hybridization https://www.biorxiv.org/content/10.1101/2025.10.24.684071v1
October 25, 2025 at 5:18 AM
Wheat and barley stripe rust pan-genome facilitates discovery of the predominant North American lineage's origin in somatic hybridization https://www.biorxiv.org/content/10.1101/2025.10.24.684071v1
Reposted by Clement Tsui PhD 🇭🇰 🇨🇦
Amazing opportunity for a postdoc. Can't think of a more exciting place (speaking from experience)
Applications are now open for two two-year UBC Biodiversity Postdoc Fellowships biodiversity.ubc.ca/training-and.... $77,000 /y + benefits and $7000 /y research funds.
October 25, 2025 at 7:00 AM
Amazing opportunity for a postdoc. Can't think of a more exciting place (speaking from experience)
High-risk clonal expansion of IMP-producing Enterobacter cloacae complex in regional Japanese healthcare settings | Antimicrobial Agents and Chemotherapy journals.asm.org/doi/10.1128/...
High-risk clonal expansion of IMP-producing Enterobacter cloacae complex in regional Japanese healthcare settings | Antimicrobial Agents and Chemotherapy
Enterobacter cloacae complex (ECC) comprises gram-negative, facultative anaerobic bacteria prevalent in
healthcare settings and recognized as notable opportunistic pathogens (1). ECC commonly causes n...
journals.asm.org
October 24, 2025 at 1:16 PM
High-risk clonal expansion of IMP-producing Enterobacter cloacae complex in regional Japanese healthcare settings | Antimicrobial Agents and Chemotherapy journals.asm.org/doi/10.1128/...
Non-conjugative plasmids limit their mobility to persist in nature: Cell Reports www.cell.com/cell-reports...
Non-conjugative plasmids limit their mobility to persist in nature
Sabnis et al. explain why non-conjugative plasmids move at a low rate in nature. While
increased mobility can easily evolve by incorporating phage DNA into plasmids, this
is disadvantageous because it...
www.cell.com
October 24, 2025 at 4:23 AM
Non-conjugative plasmids limit their mobility to persist in nature: Cell Reports www.cell.com/cell-reports...
Reposted by Clement Tsui PhD 🇭🇰 🇨🇦
🐼🦠Roles of soil microbes in shaping the nutrient accumulation of dietary bamboo of giant pandas
vist.ly/4bhs8
#SoilMicrobes #BambooShootGrowth #KeyFoodResources #PlantSoilInteractions #PlantHerbivoreInteractions #GiantPandas
vist.ly/4bhs8
#SoilMicrobes #BambooShootGrowth #KeyFoodResources #PlantSoilInteractions #PlantHerbivoreInteractions #GiantPandas
October 23, 2025 at 5:06 PM
🐼🦠Roles of soil microbes in shaping the nutrient accumulation of dietary bamboo of giant pandas
vist.ly/4bhs8
#SoilMicrobes #BambooShootGrowth #KeyFoodResources #PlantSoilInteractions #PlantHerbivoreInteractions #GiantPandas
vist.ly/4bhs8
#SoilMicrobes #BambooShootGrowth #KeyFoodResources #PlantSoilInteractions #PlantHerbivoreInteractions #GiantPandas
Persister cells in human #fungal pathogens dx.plos.org/10.1371/jour...
Persister cells in human fungal pathogens
Microbicidal persistence refers to the phenomenon whereby a subpopulation of microbial cells enters a dormant state to evade drug killing. This phenomenon is associated with antibiotic treatment failu...
dx.plos.org
October 24, 2025 at 1:59 AM
Persister cells in human #fungal pathogens dx.plos.org/10.1371/jour...
Reposted by Clement Tsui PhD 🇭🇰 🇨🇦
New #AquaticFungi to start your Wednesday!
Check out the dazzling array of new CLASSES of fungi--including those with highest frequency in freshwater.
Congrats to our #FunAqua friends, whose project features prominently in these finds! 🧡 @kristelpanksep.bsky.social @vprins.bsky.social
Check out the dazzling array of new CLASSES of fungi--including those with highest frequency in freshwater.
Congrats to our #FunAqua friends, whose project features prominently in these finds! 🧡 @kristelpanksep.bsky.social @vprins.bsky.social
Thirty novel fungal lineages: formal description based on environmental samples and DNA
Molecular analyses of soil and water commonly reveal large proportions of fungal taxa that cannot be assigned to any taxonomic or functional groups. Some of these so-called dark taxa have been encoded...
doi.org
October 22, 2025 at 8:47 AM
New #AquaticFungi to start your Wednesday!
Check out the dazzling array of new CLASSES of fungi--including those with highest frequency in freshwater.
Congrats to our #FunAqua friends, whose project features prominently in these finds! 🧡 @kristelpanksep.bsky.social @vprins.bsky.social
Check out the dazzling array of new CLASSES of fungi--including those with highest frequency in freshwater.
Congrats to our #FunAqua friends, whose project features prominently in these finds! 🧡 @kristelpanksep.bsky.social @vprins.bsky.social
Reposted by Clement Tsui PhD 🇭🇰 🇨🇦
The New England Journal of Medicine and the Center for Infectious Disease Research and Policy will be publishing regular public health alerts to replace the CDC’s Morbidity and Mortality Weekly Report, which has been paused due to the federal government shutdown.
October 22, 2025 at 1:44 AM
The New England Journal of Medicine and the Center for Infectious Disease Research and Policy will be publishing regular public health alerts to replace the CDC’s Morbidity and Mortality Weekly Report, which has been paused due to the federal government shutdown.
Reposted by Clement Tsui PhD 🇭🇰 🇨🇦
From genotype to phenotype with 1,086 near telomere-to-telomere #yeast genomes rdcu.be/eLI6i
From genotype to phenotype with 1,086 near telomere-to-telomere yeast genomes
Nature - A newly compiled atlas of species-wide structural variants and gene-based and graph pangenomes derived from highly complete assemblies of genomes from 1,086 natural isolates enable...
rdcu.be
October 19, 2025 at 9:52 AM
From genotype to phenotype with 1,086 near telomere-to-telomere #yeast genomes rdcu.be/eLI6i
Defensive fungal symbiosis on insect hindlegs | Science www.science.org/doi/10.1126/...
Defensive fungal symbiosis on insect hindlegs
Dinidorid stinkbugs were reported to possess a conspicuous tympanal organ on female hindlegs. In this study, we show that this organ is specialized to retain microbial symbionts rather than to perceiv...
www.science.org
October 19, 2025 at 9:49 AM
Defensive fungal symbiosis on insect hindlegs | Science www.science.org/doi/10.1126/...
Reposted by Clement Tsui PhD 🇭🇰 🇨🇦
What makes luciferase such a versatile reporter? 🔬
This primer covers how luciferase works, different variants available, and ways to use it to track gene expression and cellular pathways.
🔗 Read the blog:
This primer covers how luciferase works, different variants available, and ways to use it to track gene expression and cellular pathways.
🔗 Read the blog:
blog.addgene.org
Fluorescent Proteins 101: Luciferases
twp.ai
October 14, 2025 at 2:00 PM
What makes luciferase such a versatile reporter? 🔬
This primer covers how luciferase works, different variants available, and ways to use it to track gene expression and cellular pathways.
🔗 Read the blog:
This primer covers how luciferase works, different variants available, and ways to use it to track gene expression and cellular pathways.
🔗 Read the blog:
Reposted by Clement Tsui PhD 🇭🇰 🇨🇦
Reposted by Clement Tsui PhD 🇭🇰 🇨🇦
This work advances honeybee gut microbiome studies and weighs in with a frame flip of limited to no evidence of diversification between gut bacteria and bees beyond the rate of chance. ⚖️
Happy to announce that our comparative metagenomic analysis of the gut microbiota of five honeybee species - spearheaded by @aiswarya.bsky.social - is finally published in a peer-reviewed journal! rdcu.be/eKMCs @fbm-unil.bsky.social @dmf-unil.bsky.social 🧵👇
Evolution of gut microbiota across honeybee species revealed by comparative metagenomics
Nature Communications - Here, the authors perform metagenomic analysis of honeybee gut microbes, uncovering many previously unidentified species and host specific differences in composition and...
rdcu.be
October 14, 2025 at 9:01 PM
This work advances honeybee gut microbiome studies and weighs in with a frame flip of limited to no evidence of diversification between gut bacteria and bees beyond the rate of chance. ⚖️
Reposted by Clement Tsui PhD 🇭🇰 🇨🇦
Including a position in my group to work on Evolutionary Genomics of Fungal pathogens
📢 EvoMG-DN PhD applications are now open!
Join our EU-funded MSCA network and explore evolution, ageing, and disease.
👉 www.evomg-dn.eu
📅 Apply by 30 November 2025
#PhD #DoctoralTraining #MSCA #HorizonEurope #Genomics #EvolutionaryBiology #BiomedicalResearch#EarlyCareerResearchers
Join our EU-funded MSCA network and explore evolution, ageing, and disease.
👉 www.evomg-dn.eu
📅 Apply by 30 November 2025
#PhD #DoctoralTraining #MSCA #HorizonEurope #Genomics #EvolutionaryBiology #BiomedicalResearch#EarlyCareerResearchers
October 10, 2025 at 4:00 PM
Including a position in my group to work on Evolutionary Genomics of Fungal pathogens
Genetic and environmental control of parasexual reproduction in the pathogenic Candida species | Microbiology and Molecular Biology Reviews journals.asm.org/doi/10.1128/...
Genetic and environmental control of parasexual reproduction in the pathogenic Candida species | Microbiology and Molecular Biology Reviews
SUMMARYCandida species are major yeast pathogens that cause both mucosal candidiasis and life-threatening
invasive infections. Most Candida species, including Candida albicans, have long been thought ...
journals.asm.org
October 14, 2025 at 7:45 AM
Genetic and environmental control of parasexual reproduction in the pathogenic Candida species | Microbiology and Molecular Biology Reviews journals.asm.org/doi/10.1128/...
Identification of the putative gene encoding the RNA subunit of telomerase in Malassezia clade species through comparative genomic analysis url: academic.oup.com/g3journal/ar...
Validate User
academic.oup.com
October 12, 2025 at 8:54 AM
Identification of the putative gene encoding the RNA subunit of telomerase in Malassezia clade species through comparative genomic analysis url: academic.oup.com/g3journal/ar...
EASYstrata: an all-in-one workflow for genome annotation and genomic divergence analysis url: academic.oup.com/nargab/artic...
Validate User
academic.oup.com
October 10, 2025 at 7:31 AM
EASYstrata: an all-in-one workflow for genome annotation and genomic divergence analysis url: academic.oup.com/nargab/artic...