Robert Arkowitz
@robertarkowitz.bsky.social
Fascinated by fungal growth & asymmetries. Institute of Biology Valrose, CNRS-Inserm-Université Côté d’Azur, Nice. Microscopy addict, all things cell biological
Pinned
Tolerance to the antifungal drug fluconazole is mediated by tuning cytoplasmic fluidity
Treatment failure rates for fungal infections cannot be explained simply by increased rates of drug resistance. Antifungal drug tolerance, the ability of a susceptible isolate to grow in the presence ...
www.biorxiv.org
Excited to share our new study on antifungal drug tolerance in the human fungal pathogen Candida albicans.
This work highlights a link between between drug tolerance and cytoplasmic fluidity.
👇(1/3)
www.biorxiv.org/content/10.6...
#Science #Microbiology #CellBiology #Fungi
This work highlights a link between between drug tolerance and cytoplasmic fluidity.
👇(1/3)
www.biorxiv.org/content/10.6...
#Science #Microbiology #CellBiology #Fungi
Reposted by Robert Arkowitz
We gave Jay Bhattacharya an opportunity to clarify his vaccine stance: does he REALLY believe that the vaccine is worse than the disease? Instead, he launched into a defense of MAHA as the future of scientific inquiry, and never really gave us a straight answer...
@repauchincloss.bsky.social
@repauchincloss.bsky.social
December 16, 2025 at 2:55 PM
We gave Jay Bhattacharya an opportunity to clarify his vaccine stance: does he REALLY believe that the vaccine is worse than the disease? Instead, he launched into a defense of MAHA as the future of scientific inquiry, and never really gave us a straight answer...
@repauchincloss.bsky.social
@repauchincloss.bsky.social
Reposted by Robert Arkowitz
#NewResearch
During filamentous growth in the human fungal pathogen Candida albicans, a reduction in ribosome concentration leads to a decrease in macromolecular crowding. Inhibition of ribosome biogenesis can trigger filamentous growth in this pathogen.
#MicroSky 🦠
www.nature.com/articles/s41...
During filamentous growth in the human fungal pathogen Candida albicans, a reduction in ribosome concentration leads to a decrease in macromolecular crowding. Inhibition of ribosome biogenesis can trigger filamentous growth in this pathogen.
#MicroSky 🦠
www.nature.com/articles/s41...
Decreased cytoplasmic crowding via inhibition of ribosome biogenesis can trigger Candida albicans filamentous growth - Nature Microbiology
During filamentous growth in the human fungal pathogen Candida albicans, a reduction in ribosome concentration leads to a decrease in macromolecular crowding. Inhibition of ribosome biogenesis can tri...
www.nature.com
December 11, 2025 at 2:35 PM
#NewResearch
During filamentous growth in the human fungal pathogen Candida albicans, a reduction in ribosome concentration leads to a decrease in macromolecular crowding. Inhibition of ribosome biogenesis can trigger filamentous growth in this pathogen.
#MicroSky 🦠
www.nature.com/articles/s41...
During filamentous growth in the human fungal pathogen Candida albicans, a reduction in ribosome concentration leads to a decrease in macromolecular crowding. Inhibition of ribosome biogenesis can trigger filamentous growth in this pathogen.
#MicroSky 🦠
www.nature.com/articles/s41...
Reposted by Robert Arkowitz
Out now! Decreased cytoplasmic crowding via inhibition of ribosome biogenesis can trigger Candida albicans filamentous growth
@robertarkowitz.bsky.social
Read it here: rdcu.be/eT3CP
www.nature.com/articles/s41...
@robertarkowitz.bsky.social
Read it here: rdcu.be/eT3CP
www.nature.com/articles/s41...
Decreased cytoplasmic crowding via inhibition of ribosome biogenesis can trigger Candida albicans filamentous growth - Nature Microbiology
During filamentous growth in the human fungal pathogen Candida albicans, a reduction in ribosome concentration leads to a decrease in macromolecular crowding. Inhibition of ribosome biogenesis can tri...
www.nature.com
December 10, 2025 at 8:52 PM
Out now! Decreased cytoplasmic crowding via inhibition of ribosome biogenesis can trigger Candida albicans filamentous growth
@robertarkowitz.bsky.social
Read it here: rdcu.be/eT3CP
www.nature.com/articles/s41...
@robertarkowitz.bsky.social
Read it here: rdcu.be/eT3CP
www.nature.com/articles/s41...
👉Excited to share our latest work @natmicrobiol.nature.com, revealing a decrease in cytoplasmic crowding during filamentous growth in the human fungal pathogen Candida albicans. Furthermore we found that inhibition of ribosome biogenesis can trigger filamentous growth in this pathogen
rdcu.be/eT1Su
rdcu.be/eT1Su
Decreased cytoplasmic crowding via inhibition of ribosome biogenesis can trigger Candida albicans filamentous growth
Nature Microbiology - During filamentous growth in the human fungal pathogen Candida albicans, a reduction in ribosome concentration leads to a decrease in macromolecular crowding. Inhibition of...
rdcu.be
December 10, 2025 at 12:23 PM
👉Excited to share our latest work @natmicrobiol.nature.com, revealing a decrease in cytoplasmic crowding during filamentous growth in the human fungal pathogen Candida albicans. Furthermore we found that inhibition of ribosome biogenesis can trigger filamentous growth in this pathogen
rdcu.be/eT1Su
rdcu.be/eT1Su
Reposted by Robert Arkowitz
🚨 The NIH open access policy requiring immediate open access for all NIH funded papers is derailing all kinds of research programs because of the high $$$ associated with journal open access fees. Thanks to @docsirianni.bsky.social for your continued advocacy
www.insidehighered.com/news/faculty...
www.insidehighered.com/news/faculty...
The NIH Policy Holding Researchers “Hostage”
An effort to make NIH-funded research immediately accessible to the public has led to disruption and financial strain for scientists already navigating a precarious funding environment. It also spotli...
www.insidehighered.com
December 9, 2025 at 8:30 PM
🚨 The NIH open access policy requiring immediate open access for all NIH funded papers is derailing all kinds of research programs because of the high $$$ associated with journal open access fees. Thanks to @docsirianni.bsky.social for your continued advocacy
www.insidehighered.com/news/faculty...
www.insidehighered.com/news/faculty...
www.biorxiv.org
December 9, 2025 at 6:05 AM
Reposted by Robert Arkowitz
www.nytimes.com/2025/12/05/c...
Micro organisms rule!
Micro organisms rule!
What Scientists Found When a Deep Sea Mining Company Invited Them In
www.nytimes.com
December 6, 2025 at 10:53 PM
www.nytimes.com/2025/12/05/c...
Micro organisms rule!
Micro organisms rule!
Reposted by Robert Arkowitz
Reposted by Robert Arkowitz
Extensive horizontal transfer of transposable elements shapes fungal mobilomes
@currentbiology.bsky.social by @jromeijn.bsky.social et al from @mfseidl.bsky.social
www.cell.com/current-biol...
@currentbiology.bsky.social by @jromeijn.bsky.social et al from @mfseidl.bsky.social
www.cell.com/current-biol...
Extensive horizontal transfer of transposable elements shapes fungal mobilomes
Romeijn et al. reveal that horizontal transposon transfer is widespread in fungi,
contributing up to 70% of transposon content in some taxa. The authors uncover thousands
of events across diverse line...
www.cell.com
December 6, 2025 at 9:22 AM
Extensive horizontal transfer of transposable elements shapes fungal mobilomes
@currentbiology.bsky.social by @jromeijn.bsky.social et al from @mfseidl.bsky.social
www.cell.com/current-biol...
@currentbiology.bsky.social by @jromeijn.bsky.social et al from @mfseidl.bsky.social
www.cell.com/current-biol...
Reposted by Robert Arkowitz
GTPBP1 is a GTPase implicated in neurodevelopment. Our cryo-EM maps show GTPBP1 delivering tRNA to ribosome.
Due to delayed GTPase dissociation, mRNA decoding is more stringent than with bona fide delivery factor eEF1A.
Congrats to Denis Susorov and collab with Pestova lab! tinyurl.com/3smdvt3v
Due to delayed GTPase dissociation, mRNA decoding is more stringent than with bona fide delivery factor eEF1A.
Congrats to Denis Susorov and collab with Pestova lab! tinyurl.com/3smdvt3v
December 5, 2025 at 6:30 PM
GTPBP1 is a GTPase implicated in neurodevelopment. Our cryo-EM maps show GTPBP1 delivering tRNA to ribosome.
Due to delayed GTPase dissociation, mRNA decoding is more stringent than with bona fide delivery factor eEF1A.
Congrats to Denis Susorov and collab with Pestova lab! tinyurl.com/3smdvt3v
Due to delayed GTPase dissociation, mRNA decoding is more stringent than with bona fide delivery factor eEF1A.
Congrats to Denis Susorov and collab with Pestova lab! tinyurl.com/3smdvt3v
Reposted by Robert Arkowitz
Common Infection Is Rapidly Becoming Resistant to Drugs, Scientists Warn : ScienceAlert share.google/zqPGnNCYaZ14...
Common Infection Is Rapidly Becoming Resistant to Drugs, Scientists Warn
Thrush is one of the most common infections in the world.
share.google
December 3, 2025 at 12:21 AM
Common Infection Is Rapidly Becoming Resistant to Drugs, Scientists Warn : ScienceAlert share.google/zqPGnNCYaZ14...
Excited to share our new study on antifungal drug tolerance in the human fungal pathogen Candida albicans.
This work highlights a link between between drug tolerance and cytoplasmic fluidity.
👇(1/3)
www.biorxiv.org/content/10.6...
#Science #Microbiology #CellBiology #Fungi
This work highlights a link between between drug tolerance and cytoplasmic fluidity.
👇(1/3)
www.biorxiv.org/content/10.6...
#Science #Microbiology #CellBiology #Fungi
Tolerance to the antifungal drug fluconazole is mediated by tuning cytoplasmic fluidity
Treatment failure rates for fungal infections cannot be explained simply by increased rates of drug resistance. Antifungal drug tolerance, the ability of a susceptible isolate to grow in the presence ...
www.biorxiv.org
December 4, 2025 at 3:52 PM
Excited to share our new study on antifungal drug tolerance in the human fungal pathogen Candida albicans.
This work highlights a link between between drug tolerance and cytoplasmic fluidity.
👇(1/3)
www.biorxiv.org/content/10.6...
#Science #Microbiology #CellBiology #Fungi
This work highlights a link between between drug tolerance and cytoplasmic fluidity.
👇(1/3)
www.biorxiv.org/content/10.6...
#Science #Microbiology #CellBiology #Fungi
Reposted by Robert Arkowitz
MIT chemists synthesize a fungal compound that holds promise for treating brain cancer news.mit.edu/2025/mit-che...
Preliminary studies find derivatives of the compound, known as verticillin A, can kill some types of glioma cells.
Preliminary studies find derivatives of the compound, known as verticillin A, can kill some types of glioma cells.
MIT chemists synthesize a fungal compound that holds promise for treating brain cancer
MIT chemists synthesized a fungal compound that holds promise for treating brain cancer. Early studies find derivatives of the compound, verticillin A, can kill certain glioma cells.
news.mit.edu
December 4, 2025 at 6:53 AM
MIT chemists synthesize a fungal compound that holds promise for treating brain cancer news.mit.edu/2025/mit-che...
Preliminary studies find derivatives of the compound, known as verticillin A, can kill some types of glioma cells.
Preliminary studies find derivatives of the compound, known as verticillin A, can kill some types of glioma cells.
Reposted by Robert Arkowitz
An 8-nm precise map in live cells, which revealed #actin aster formation by #myosin V-driven transport of #formin.
Happy to see this work now out! 😃
In collaboration with @kaksonen.bsky.social lab
#yeast #pombe #cell_fusion
@biology-unige.bsky.social
Happy to see this work now out! 😃
In collaboration with @kaksonen.bsky.social lab
#yeast #pombe #cell_fusion
@biology-unige.bsky.social
New work by @valthomas.bsky.social et al. in @sophiemartinlab.bsky.social provides a live, 8-nm precision map of the actin fusion focus for cell-cell fusion in S. #pombe. This reveals #actin aster formation by #myosin Myo52-driven transport of the formin Fus1 nucleator rupress.org/jcb/article/...
December 4, 2025 at 7:22 AM
An 8-nm precise map in live cells, which revealed #actin aster formation by #myosin V-driven transport of #formin.
Happy to see this work now out! 😃
In collaboration with @kaksonen.bsky.social lab
#yeast #pombe #cell_fusion
@biology-unige.bsky.social
Happy to see this work now out! 😃
In collaboration with @kaksonen.bsky.social lab
#yeast #pombe #cell_fusion
@biology-unige.bsky.social
Reposted by Robert Arkowitz
#Antifungal resistance is making #thrush hard to treat ...
| #fungi | #infection | #Candida | #yeast | #drugs | Via @theconversation.com
| #fungi | #infection | #Candida | #yeast | #drugs | Via @theconversation.com
Antifungal resistance is making thrush hard to treat – here’s why
Infections are becoming harder to treat because the fungi are adapting to survive antifungal drugs – but this isn’t happening by chance.
theconversation.com
December 3, 2025 at 6:02 PM
#Antifungal resistance is making #thrush hard to treat ...
| #fungi | #infection | #Candida | #yeast | #drugs | Via @theconversation.com
| #fungi | #infection | #Candida | #yeast | #drugs | Via @theconversation.com