Syma Khalid
@sykhalid.bsky.social
Prof of Computational Microbiology. Oxford Biochemistry & St Anne’s College. Bacterial Cell Envelopes. LFC fan 🌈
Reposted by Syma Khalid
Check out our latest paper on the glycine receptor with
@chakrapanilab.bsky.social
where we show the interplay between the orthosteric and allosteric binding sites.
www.science.org/doi/10.1126/...
@chakrapanilab.bsky.social
where we show the interplay between the orthosteric and allosteric binding sites.
www.science.org/doi/10.1126/...
Structural basis for domain coupling in heteromeric glycine receptors revealed by an atypical allosteric agonist
Counteracting ligands stabilize glycine receptor states revealing mechanisms of pentameric ligand-gated channel allostery.
www.science.org
February 14, 2026 at 8:24 AM
Check out our latest paper on the glycine receptor with
@chakrapanilab.bsky.social
where we show the interplay between the orthosteric and allosteric binding sites.
www.science.org/doi/10.1126/...
@chakrapanilab.bsky.social
where we show the interplay between the orthosteric and allosteric binding sites.
www.science.org/doi/10.1126/...
Reposted by Syma Khalid
Check out our latest review of advanced sampling of membrane transporter dynamics - link.springer.com/chapter/10.1...
Great work from Jon Colburn and @simonlichtinger.bsky.social !
Great work from Jon Colburn and @simonlichtinger.bsky.social !
Advanced Computational Methods in Protein Simulations: A Case Study of Enhanced Sampling Applied to Membrane Transporters
We review the use of state-of-the-art enhanced sampling techniques in molecular dynamics (MD) simulations. We briefly introduce the principles and practical considerations underlying the application o...
link.springer.com
February 8, 2026 at 10:01 PM
Check out our latest review of advanced sampling of membrane transporter dynamics - link.springer.com/chapter/10.1...
Great work from Jon Colburn and @simonlichtinger.bsky.social !
Great work from Jon Colburn and @simonlichtinger.bsky.social !
View of the @britishlibrary.bsky.social from my hotel. A long day again, but a good day
February 10, 2026 at 10:13 PM
View of the @britishlibrary.bsky.social from my hotel. A long day again, but a good day
Ancient wine-making tradition in Pakistan. An interesting read imho
www.wineenthusiast.com/kalash-wine-...
www.wineenthusiast.com/kalash-wine-...
www.wineenthusiast.com
February 7, 2026 at 5:52 PM
Ancient wine-making tradition in Pakistan. An interesting read imho
www.wineenthusiast.com/kalash-wine-...
www.wineenthusiast.com/kalash-wine-...
Reposted by Syma Khalid
Yesterday we came together to honour Professor Raymond Dwek through the naming of the Raymond Dwek Seminar Room. Raymond's family (pictured) joined the celebration and Raymond was visibly touched, saying: "Thank you for this amazing gesture. I'm humbled by it, but I will treasure it."
February 6, 2026 at 2:29 PM
Yesterday we came together to honour Professor Raymond Dwek through the naming of the Raymond Dwek Seminar Room. Raymond's family (pictured) joined the celebration and Raymond was visibly touched, saying: "Thank you for this amazing gesture. I'm humbled by it, but I will treasure it."
Andrew & Fergie hiding in the jungle to escape the Epstein allegations.
Credit: Sahdia Khalid
Credit: Sahdia Khalid
February 6, 2026 at 12:42 PM
Andrew & Fergie hiding in the jungle to escape the Epstein allegations.
Credit: Sahdia Khalid
Credit: Sahdia Khalid
Reposted by Syma Khalid
In today's @scienceofthetimes.bsky.social @sykhalid.bsky.social ^& I talk with Adrian Wooflson about his new book "On the Future of Species". Where AI and genome editing meet, new species lie, and ethical questions emerge. podcasts.apple.com/gb/podcast/s...
Where Genome Editing and Artificial Intelligence meet New Species Lie
Podcast Episode · Science Of The Times · 05/02/2026 · 45m
podcasts.apple.com
February 6, 2026 at 10:51 AM
In today's @scienceofthetimes.bsky.social @sykhalid.bsky.social ^& I talk with Adrian Wooflson about his new book "On the Future of Species". Where AI and genome editing meet, new species lie, and ethical questions emerge. podcasts.apple.com/gb/podcast/s...
Reposted by Syma Khalid
#OnThisDay in 1826, the first paper to be written by a woman was read at a Royal Society meeting. The paper, by noted polymath Mary Somerville, was read at the meeting by her husband, as she wasn't permitted to attend. https://bit.ly/2A3Cj2N
February 2, 2026 at 2:59 PM
#OnThisDay in 1826, the first paper to be written by a woman was read at a Royal Society meeting. The paper, by noted polymath Mary Somerville, was read at the meeting by her husband, as she wasn't permitted to attend. https://bit.ly/2A3Cj2N
A gift of an article from the inimitable Colin Kleanthous as he says a moving farewell to his laboratory. A brave, unrepentant and scientifically brilliant journey is described - please have a read, friends.
www.jbc.org/article/S002...
www.jbc.org/article/S002...
Bacteriocin biophysics: From protein-protein interaction models to navigators of the bacterial cell envelope
Bacteriocins are toxins deployed by bacteria to kill their competitors. Here, I reflect
on my laboratory’s work on protein bacteriocins and their immunity proteins from Gram-negative
bacteria. We unco...
www.jbc.org
February 2, 2026 at 12:39 PM
A gift of an article from the inimitable Colin Kleanthous as he says a moving farewell to his laboratory. A brave, unrepentant and scientifically brilliant journey is described - please have a read, friends.
www.jbc.org/article/S002...
www.jbc.org/article/S002...
Reposted by Syma Khalid
Scientists are concerned that curiosity-driven research is set to be further cut back after three research councils confirmed they have paused funding opportunities. @jgro-the.bsky.social reports #academicsky #researchfunding
https://ow.ly/lpvO50Y67ku
https://ow.ly/lpvO50Y67ku
Three UK research councils suspend funding opportunities
Temporary block on grant applications by MRC, BBSRC and EPSRC heightens concerns over funding cuts
ow.ly
January 30, 2026 at 4:08 PM
Scientists are concerned that curiosity-driven research is set to be further cut back after three research councils confirmed they have paused funding opportunities. @jgro-the.bsky.social reports #academicsky #researchfunding
https://ow.ly/lpvO50Y67ku
https://ow.ly/lpvO50Y67ku
Long day, finished with a really fun dinner at Merton college Oxford
January 29, 2026 at 11:39 PM
Long day, finished with a really fun dinner at Merton college Oxford
Football has entered a dark era
January 24, 2026 at 8:25 PM
Football has entered a dark era
We’re not winning the league this season, but at least we’ve not lost to utterly unlikeable Arteta.
January 9, 2026 at 6:10 PM
We’re not winning the league this season, but at least we’ve not lost to utterly unlikeable Arteta.
Reposted by Syma Khalid
Professor Raymond Dwek and colleagues @ox.ac.uk urge renewed investment in host-targeting broad-spectrum antivirals as a ‘global shield’ if vaccines falter. Read more ⬇️
If vaccines falter, broad-spectrum antivirals provide a global shield
Professor Raymond Dwek and colleagues urge renewed investment in host-targeting broad-spectrum antivirals
bit.ly
January 9, 2026 at 10:31 AM
Professor Raymond Dwek and colleagues @ox.ac.uk urge renewed investment in host-targeting broad-spectrum antivirals as a ‘global shield’ if vaccines falter. Read more ⬇️
December in Oxford
December 18, 2025 at 10:43 PM
December in Oxford
Reposted by Syma Khalid
Poppit the Classics School dog is getting into the festive spirit and wishes all her fans the very best.
December 9, 2025 at 9:20 PM
Poppit the Classics School dog is getting into the festive spirit and wishes all her fans the very best.
Wise words from @profpaulbehrens.bsky.social!
You can hear more from Paul here on our podcast: How To Build A Sustainable World - Paul Behrens.
youtu.be/VQrGldPO7P8
@timcoulson.bsky.social
You can hear more from Paul here on our podcast: How To Build A Sustainable World - Paul Behrens.
youtu.be/VQrGldPO7P8
@timcoulson.bsky.social
December 6, 2025 at 11:23 AM
Wise words from @profpaulbehrens.bsky.social!
You can hear more from Paul here on our podcast: How To Build A Sustainable World - Paul Behrens.
youtu.be/VQrGldPO7P8
@timcoulson.bsky.social
You can hear more from Paul here on our podcast: How To Build A Sustainable World - Paul Behrens.
youtu.be/VQrGldPO7P8
@timcoulson.bsky.social
England batting collapse…. And I land back at Heathrow in time for the Liverpool game- it’s just all too uplifting 🤦🏽♀️
December 6, 2025 at 11:03 AM
England batting collapse…. And I land back at Heathrow in time for the Liverpool game- it’s just all too uplifting 🤦🏽♀️
Watching Crawley bat is pure pain
December 6, 2025 at 9:47 AM
Watching Crawley bat is pure pain
Our paper on polymyxin interacting with the E. coli outer membrane is out! Simulations by the very talented @dheerajprakaash.bsky.social www.nature.com/articles/s42...
To scale outer membrane protein island simulated at coarse-grained resolution with portions refined at all atom resolution.
To scale outer membrane protein island simulated at coarse-grained resolution with portions refined at all atom resolution.
Polymyxins slow down lateral diffusion of proteins and lipopolysaccharide in the E. coli outer membrane - Communications Biology
Multi-scale molecular dynamics simulations reveal that polymyxins form polymyxin-protein aggregates upon associating with the E. coli outer membrane thereby reducing lateral mobility of outer membrane...
www.nature.com
December 5, 2025 at 3:42 PM
Our paper on polymyxin interacting with the E. coli outer membrane is out! Simulations by the very talented @dheerajprakaash.bsky.social www.nature.com/articles/s42...
To scale outer membrane protein island simulated at coarse-grained resolution with portions refined at all atom resolution.
To scale outer membrane protein island simulated at coarse-grained resolution with portions refined at all atom resolution.
Reposted by Syma Khalid
"Why do we put hurdles in the way of the people that are actually going to drive our economy? It makes zero sense."
Prof Sir Paul Nurse, Nobel prize winning scientist, says the UK's scientific future is being put at risk
www.bbc.co.uk/news/article...
Prof Sir Paul Nurse, Nobel prize winning scientist, says the UK's scientific future is being put at risk
www.bbc.co.uk/news/article...
Top UK scientist says research visa restrictions endanger economy
Prof Sir Paul Nurse says the UK is
www.bbc.co.uk
December 5, 2025 at 7:34 AM
"Why do we put hurdles in the way of the people that are actually going to drive our economy? It makes zero sense."
Prof Sir Paul Nurse, Nobel prize winning scientist, says the UK's scientific future is being put at risk
www.bbc.co.uk/news/article...
Prof Sir Paul Nurse, Nobel prize winning scientist, says the UK's scientific future is being put at risk
www.bbc.co.uk/news/article...
Reposted by Syma Khalid
My department at California State University Northridge is hiring! We're looking for a new colleague studying microbiology or molecular/cellular biology. I'm not on the search committee, but happy to answer questions about the department and campus, and life in LA
buff.ly/Pc1KOaC
buff.ly/Pc1KOaC
Career Opportunities
Applicant Log-In
careers.pageuppeople.com
December 4, 2025 at 7:19 PM
My department at California State University Northridge is hiring! We're looking for a new colleague studying microbiology or molecular/cellular biology. I'm not on the search committee, but happy to answer questions about the department and campus, and life in LA
buff.ly/Pc1KOaC
buff.ly/Pc1KOaC
I appear to be in Heidelberg
December 3, 2025 at 5:44 PM
I appear to be in Heidelberg
Better ditch my horse & cart for the last bit of the trip to EMBL.
December 3, 2025 at 1:16 PM
Better ditch my horse & cart for the last bit of the trip to EMBL.
New podcast episode just dropped! @timcoulson.bsky.social I are joined by Simon Newstead and David Bennett who have identified a new genetic link to chronic pain - solved the structure of the protein that the gene encodes and linked its function to pain.
youtu.be/ETGzmy_BfCg
youtu.be/ETGzmy_BfCg
Science Of The Times Ep 31 Cracking The Code of Chronic Pain
YouTube video by Science Of The Times Podcast
youtu.be
December 1, 2025 at 8:40 AM
New podcast episode just dropped! @timcoulson.bsky.social I are joined by Simon Newstead and David Bennett who have identified a new genetic link to chronic pain - solved the structure of the protein that the gene encodes and linked its function to pain.
youtu.be/ETGzmy_BfCg
youtu.be/ETGzmy_BfCg