Andreas Müller
@andimicroscopy.bsky.social
Scientist at Paul Langerhans Institute Dresden. Interested in the structural features of pancreatic beta cell function and signaling. 🔬
Pinned
Ok, let's start this thing here with my favorite 3D animation connected to our recent paper on structure and interactions of beta cell primary cilia. www.nature.com/articles/s41...
Still super ecited about cilia-axon contacts in the pancreas.
Still super ecited about cilia-axon contacts in the pancreas.
Reposted by Andreas Müller
My new ImageJ / Fiji toolkit is out 🔥! The goal is to make image handling & visualization easy, with an intuitive interface! Install it on Fiji with the "Image Viewer" update site
#microscopy #ImageJ #FluorescenceFriday #microscopyMonday
imagej.net/plugins/imag...
#microscopy #ImageJ #FluorescenceFriday #microscopyMonday
imagej.net/plugins/imag...
November 4, 2025 at 10:40 PM
My new ImageJ / Fiji toolkit is out 🔥! The goal is to make image handling & visualization easy, with an intuitive interface! Install it on Fiji with the "Image Viewer" update site
#microscopy #ImageJ #FluorescenceFriday #microscopyMonday
imagej.net/plugins/imag...
#microscopy #ImageJ #FluorescenceFriday #microscopyMonday
imagej.net/plugins/imag...
Reposted by Andreas Müller
As a neuroscientist, I’d suggest there is a profound disconnect between what *some* computer scientists think is representative of “intelligence”, cognitive ability, or descriptions of consciousness from some in AI work.
LLMs are not how neural systems process information, nor how brains function.
LLMs are not how neural systems process information, nor how brains function.
November 6, 2025 at 5:19 PM
As a neuroscientist, I’d suggest there is a profound disconnect between what *some* computer scientists think is representative of “intelligence”, cognitive ability, or descriptions of consciousness from some in AI work.
LLMs are not how neural systems process information, nor how brains function.
LLMs are not how neural systems process information, nor how brains function.
Reposted by Andreas Müller
We are looking for motivated #postdocs to join the lab! Biochemistry/microbiology/cryo-EM experience? Excited by #cryo-EM/ET, #chromatin? ❄️🧬🧫
Interdisciplinary projects, top EMBL facilities!
Email CV + short cover letter → svetlana.dodonova@embl.de
Info about the group: www.embl.org/groups/dodon...
Interdisciplinary projects, top EMBL facilities!
Email CV + short cover letter → svetlana.dodonova@embl.de
Info about the group: www.embl.org/groups/dodon...
Dodonova Group – Organisational principles and 3D architecture of archaeal chromatin
www.embl.org
October 15, 2025 at 10:38 AM
We are looking for motivated #postdocs to join the lab! Biochemistry/microbiology/cryo-EM experience? Excited by #cryo-EM/ET, #chromatin? ❄️🧬🧫
Interdisciplinary projects, top EMBL facilities!
Email CV + short cover letter → svetlana.dodonova@embl.de
Info about the group: www.embl.org/groups/dodon...
Interdisciplinary projects, top EMBL facilities!
Email CV + short cover letter → svetlana.dodonova@embl.de
Info about the group: www.embl.org/groups/dodon...
Reposted by Andreas Müller
Everything you wanted to know about #cilia & #signaling in one big beautiful poster format from field thought leaders @wachtenlab.bsky.social & @sorentc.bsky.social- from our just live @jcellsci.bsky.social Special Issue… 🤩🤩🤩
I’m excited to share this collaborative work with Prof. Dagmar Wachten (@wachtenlab.bsky.social), providing an accessible overview of primary cilia signalling and recent advances in cellular signaling in health and disease. Many thanks to Dagmar for a fantastic collaboration! doi.org/10.1242/jcs....
Primary cilia signalling at a glance
Summary: We explore the primary cilium as a master regulator of cellular communication that integrates diverse signalling pathways to guide development and maintain homeostasis. Its dysfunction trigge...
doi.org
October 30, 2025 at 1:11 PM
Everything you wanted to know about #cilia & #signaling in one big beautiful poster format from field thought leaders @wachtenlab.bsky.social & @sorentc.bsky.social- from our just live @jcellsci.bsky.social Special Issue… 🤩🤩🤩
Reposted by Andreas Müller
Our Special Issue on Cilia and Flagella: from Basic Biology to Disease, guest edited by @cilialab.bsky.social and @lottepedersen.bsky.social, is building. We’ll be highlighting all the articles over the next couple of weeks. Follow along at #JCSciliaSI.
journals.biologists.com/jcs/issue/13...
journals.biologists.com/jcs/issue/13...
Volume 138 Issue 20 | Journal of Cell Science | The Company of Biologists
journals.biologists.com
October 27, 2025 at 10:30 AM
Our Special Issue on Cilia and Flagella: from Basic Biology to Disease, guest edited by @cilialab.bsky.social and @lottepedersen.bsky.social, is building. We’ll be highlighting all the articles over the next couple of weeks. Follow along at #JCSciliaSI.
journals.biologists.com/jcs/issue/13...
journals.biologists.com/jcs/issue/13...
Reposted by Andreas Müller
The dark truth behind FormatMyPaper.com
Beware giving this site your unpublished data
Users noticed the website had fake testimonials and a domain name registered seemingly overnight.
https://ubadah.substack.com/p/beware-giving-this-site-your-unpublished\
October 24, 2025 at 12:11 AM
The dark truth behind FormatMyPaper.com
Reposted by Andreas Müller
Are you studying synapses in electron microscopy? Tired of annotating vesicles? We have the tool for you! SynapseNet implements automatic segmentation and analysis of vesicles and other synaptic structures and has now been published:
www.molbiolcell.org/doi/full/10....
www.molbiolcell.org/doi/full/10....
October 17, 2025 at 11:09 AM
Are you studying synapses in electron microscopy? Tired of annotating vesicles? We have the tool for you! SynapseNet implements automatic segmentation and analysis of vesicles and other synaptic structures and has now been published:
www.molbiolcell.org/doi/full/10....
www.molbiolcell.org/doi/full/10....
Reposted by Andreas Müller
Ingenious concept - light sheet on serial sections by photo-etching the expanded hydrogel, layer by layer.
Photo-sectioning is quite slow, and the volumetric images are insanely large and complex, but the data look wonderful.
www.science.org/doi/10.1126/...
Photo-sectioning is quite slow, and the volumetric images are insanely large and complex, but the data look wonderful.
www.science.org/doi/10.1126/...
October 17, 2025 at 7:00 AM
Ingenious concept - light sheet on serial sections by photo-etching the expanded hydrogel, layer by layer.
Photo-sectioning is quite slow, and the volumetric images are insanely large and complex, but the data look wonderful.
www.science.org/doi/10.1126/...
Photo-sectioning is quite slow, and the volumetric images are insanely large and complex, but the data look wonderful.
www.science.org/doi/10.1126/...
Reposted by Andreas Müller
Reposted by Andreas Müller
1925: On this date, 100 years ago, The Company of Biologists is founded by George Parker Bidder III. Throughout today, we will be posting some of our key milestones. Read more about the past 100 years at bit.ly/3WnTVA1.
October 15, 2025 at 8:04 AM
1925: On this date, 100 years ago, The Company of Biologists is founded by George Parker Bidder III. Throughout today, we will be posting some of our key milestones. Read more about the past 100 years at bit.ly/3WnTVA1.
Reposted by Andreas Müller
I found these immune cells just finished mitosis but their midbody is still yet to be resolved. How cool? If you zoom in to the midbody, you can see its classical shape just like in the textbooks. I love these little details.
October 14, 2025 at 10:56 AM
I found these immune cells just finished mitosis but their midbody is still yet to be resolved. How cool? If you zoom in to the midbody, you can see its classical shape just like in the textbooks. I love these little details.
Reposted by Andreas Müller
Join us *next Monday*!
#CrickXrays25
X-ray #nanoimaging of biological tissues
🇬🇧🌐 @crick.ac.uk & online
tinyurl.com/crickxrays25
Sponsored by @dectris.bsky.social, @webknossos.org and @biologists.bsky.social and backed by @brukercorporation.bsky.social and Histomography
#CrickXrays25
X-ray #nanoimaging of biological tissues
🇬🇧🌐 @crick.ac.uk & online
tinyurl.com/crickxrays25
Sponsored by @dectris.bsky.social, @webknossos.org and @biologists.bsky.social and backed by @brukercorporation.bsky.social and Histomography
October 7, 2025 at 9:20 AM
Join us *next Monday*!
#CrickXrays25
X-ray #nanoimaging of biological tissues
🇬🇧🌐 @crick.ac.uk & online
tinyurl.com/crickxrays25
Sponsored by @dectris.bsky.social, @webknossos.org and @biologists.bsky.social and backed by @brukercorporation.bsky.social and Histomography
#CrickXrays25
X-ray #nanoimaging of biological tissues
🇬🇧🌐 @crick.ac.uk & online
tinyurl.com/crickxrays25
Sponsored by @dectris.bsky.social, @webknossos.org and @biologists.bsky.social and backed by @brukercorporation.bsky.social and Histomography
Reposted by Andreas Müller
We present multi-immersion Oblique Plane microscope (miOPM), a light-sheet platform that can be adapted to a wide range of applications, from sensitive live cell imaging to imaging organs and cleared tissues.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
October 6, 2025 at 5:52 PM
We present multi-immersion Oblique Plane microscope (miOPM), a light-sheet platform that can be adapted to a wide range of applications, from sensitive live cell imaging to imaging organs and cleared tissues.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Andreas Müller
🪰 A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system—a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the millions of connections between them.
🔗 https://hhmi.news/4o3EJnk
🔗 https://hhmi.news/4o3EJnk
October 6, 2025 at 2:16 PM
🪰 A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system—a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the millions of connections between them.
🔗 https://hhmi.news/4o3EJnk
🔗 https://hhmi.news/4o3EJnk
Reposted by Andreas Müller
I’m happy to share some plugins I’ve been developping this summer: "Channels and Contrast" and LUTs Manager!
I can’t find new bugs and ideas by now so I need your help to please test them in your machines and report bugs, feedbacks and ideas! forum.image.sc/t/looking-fo...
I can’t find new bugs and ideas by now so I need your help to please test them in your machines and report bugs, feedbacks and ideas! forum.image.sc/t/looking-fo...
October 4, 2025 at 11:50 AM
I’m happy to share some plugins I’ve been developping this summer: "Channels and Contrast" and LUTs Manager!
I can’t find new bugs and ideas by now so I need your help to please test them in your machines and report bugs, feedbacks and ideas! forum.image.sc/t/looking-fo...
I can’t find new bugs and ideas by now so I need your help to please test them in your machines and report bugs, feedbacks and ideas! forum.image.sc/t/looking-fo...
Reposted by Andreas Müller
Check the live stream of the Göttingen Expansion Forum 2025 if you're interested! I think the link changes every day will try to update. Program is here (pdf link): www.rizzoli-lab.de/wp-content/u...
September 28, 2025 at 8:52 AM
Check the live stream of the Göttingen Expansion Forum 2025 if you're interested! I think the link changes every day will try to update. Program is here (pdf link): www.rizzoli-lab.de/wp-content/u...
Reposted by Andreas Müller
Oh yes-the one and only Robert Haase @haesleinhuepf.bsky.social
From #GrandTheftAuto to the impact AI is having on #bioimaging.
+the challenges of creating AI courses for bioimage analysis, & his unique perspective as a programmer-turned-biologist.
Stream- bit.ly/microscopist...
@globias.bsky.social
From #GrandTheftAuto to the impact AI is having on #bioimaging.
+the challenges of creating AI courses for bioimage analysis, & his unique perspective as a programmer-turned-biologist.
Stream- bit.ly/microscopist...
@globias.bsky.social
The Microscopists | Robert Haase (Leipzig University)
We're thrilled to bring you the latest episode of The Microscopists, this time featuring Robert Haase, Lecturer and Training Coordinator at Leipzig University. In this episode, Robert chats about t...
bit.ly
September 19, 2025 at 11:15 AM
Oh yes-the one and only Robert Haase @haesleinhuepf.bsky.social
From #GrandTheftAuto to the impact AI is having on #bioimaging.
+the challenges of creating AI courses for bioimage analysis, & his unique perspective as a programmer-turned-biologist.
Stream- bit.ly/microscopist...
@globias.bsky.social
From #GrandTheftAuto to the impact AI is having on #bioimaging.
+the challenges of creating AI courses for bioimage analysis, & his unique perspective as a programmer-turned-biologist.
Stream- bit.ly/microscopist...
@globias.bsky.social
Reposted by Andreas Müller
Our new preprint is up! This is the main postdoc work of @wiesner-t.bsky.social focusing on exocytosis along the axon shaft and its regulation by the sub membrane actin-spectrin scaffold: www.biorxiv.org/content/10.1...
Read the thread below for a summary of our findings 🧵1/11
Read the thread below for a summary of our findings 🧵1/11
September 17, 2025 at 2:55 PM
Our new preprint is up! This is the main postdoc work of @wiesner-t.bsky.social focusing on exocytosis along the axon shaft and its regulation by the sub membrane actin-spectrin scaffold: www.biorxiv.org/content/10.1...
Read the thread below for a summary of our findings 🧵1/11
Read the thread below for a summary of our findings 🧵1/11
I wrote an article summarizing our recent findings of beta cell cilia - neuron contacts. It was fun to elaborate a bit on the exploration of #openaccess #volumeEM datasets: analyticalscience.wiley.com/content/arti...
Volume EM uncovers hidden tissue contacts - 2025 - Wiley Analytical Science
The largest repository of validated, free and subject-focused e-publications and online seminars in analytical science covering latest techniques, equipment, original research, editorials, and industr...
analyticalscience.wiley.com
September 15, 2025 at 12:24 PM
I wrote an article summarizing our recent findings of beta cell cilia - neuron contacts. It was fun to elaborate a bit on the exploration of #openaccess #volumeEM datasets: analyticalscience.wiley.com/content/arti...
Reposted by Andreas Müller
Super happy to see CLEM-Reg out in @natmethods.nature.com! A short thread on the algorithm behind it and how to try it out for yourself🧵(1/9)
www.nature.com/articles/s41...
www.nature.com/articles/s41...
CLEM-Reg: an automated point cloud-based registration algorithm for volume correlative light and electron microscopy - Nature Methods
CLEM-Reg automates the three-dimensional alignment of volume correlative light and electron microscopy datasets by leveraging probabilistic point cloud registration techniques for fast and accurate re...
www.nature.com
September 10, 2025 at 9:37 AM
Super happy to see CLEM-Reg out in @natmethods.nature.com! A short thread on the algorithm behind it and how to try it out for yourself🧵(1/9)
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Andreas Müller
Our new preprint is about the airway epithelium microtubule network, cilia, basal body protein composition, averaging of volumetric fluorescence data, and expansion microscopy.
Four years of very hard work from our very talented Emma van Grinsven. www.biorxiv.org/content/10.1... (1/N)
Four years of very hard work from our very talented Emma van Grinsven. www.biorxiv.org/content/10.1... (1/N)
September 5, 2025 at 3:37 PM
Our new preprint is about the airway epithelium microtubule network, cilia, basal body protein composition, averaging of volumetric fluorescence data, and expansion microscopy.
Four years of very hard work from our very talented Emma van Grinsven. www.biorxiv.org/content/10.1... (1/N)
Four years of very hard work from our very talented Emma van Grinsven. www.biorxiv.org/content/10.1... (1/N)
Reposted by Andreas Müller
It's TODAY! Join us at the #VirtualPub for a talk by Rene' In't Zandt on “Metabolic MR Imaging in an experimental and clinical setting”
Hope to see you there!
🕐 13:00 CEST
More information ⤵️
www.eurobioimaging.eu/our-events/v...
Hope to see you there!
🕐 13:00 CEST
More information ⤵️
www.eurobioimaging.eu/our-events/v...
September 5, 2025 at 6:45 AM
It's TODAY! Join us at the #VirtualPub for a talk by Rene' In't Zandt on “Metabolic MR Imaging in an experimental and clinical setting”
Hope to see you there!
🕐 13:00 CEST
More information ⤵️
www.eurobioimaging.eu/our-events/v...
Hope to see you there!
🕐 13:00 CEST
More information ⤵️
www.eurobioimaging.eu/our-events/v...
Reposted by Andreas Müller
We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)
September 4, 2025 at 8:22 AM
We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)
Reposted by Andreas Müller
We have a fully funded 3y postdoc position open!!!! Come join us @mpi-cbg.de and @poldresden.bsky.social to understand the role of Membranes in Controlling Biogenic Crystallization :) this is part of our #HFSP funded project with @noemijimenezrojo.bsky.social and @vmonje.bsky.social! Applications👇
The #MaxPlanckPostdocProgram offers a guaranteed contract of at least 3 years, targeted mentoring, and career workshops. The call for applications is open now! 🚀 Take advantage of this opportunity and browse the job vacancies. www.mpg.de/en/max-planc...
September 1, 2025 at 9:17 PM
We have a fully funded 3y postdoc position open!!!! Come join us @mpi-cbg.de and @poldresden.bsky.social to understand the role of Membranes in Controlling Biogenic Crystallization :) this is part of our #HFSP funded project with @noemijimenezrojo.bsky.social and @vmonje.bsky.social! Applications👇
Reposted by Andreas Müller
Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1...
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
August 28, 2025 at 7:03 AM
Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1...
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social