Paul & Virginie - Centriole Lab
@centriolelab.bsky.social
Virginie Hamel & Paul Guichard Lab at University of Geneva
#cryoEM/ET❄️ and #UExM ⚗️ #ExpansionMicroscopy #TeamTomo
Genève, Suisse 🇨🇭
https://mocel.unige.ch/research-groups/guichard-hamel/overv
#cryoEM/ET❄️ and #UExM ⚗️ #ExpansionMicroscopy #TeamTomo
Genève, Suisse 🇨🇭
https://mocel.unige.ch/research-groups/guichard-hamel/overv
Pinned
Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1...
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
Reposted by Paul & Virginie - Centriole Lab
In 2017 we showed that homomers evolve on the edge of supramolecular self-assembly. Here we show how to exploit this vulnerability so that ALL homomers can become bona fide drug-🎯. Delighted that Aim 3 of our @erc.europa.eu finally polymerized! Manuscript: 👉 rdcu.be/e27bT
February 9, 2026 at 5:36 PM
In 2017 we showed that homomers evolve on the edge of supramolecular self-assembly. Here we show how to exploit this vulnerability so that ALL homomers can become bona fide drug-🎯. Delighted that Aim 3 of our @erc.europa.eu finally polymerized! Manuscript: 👉 rdcu.be/e27bT
Reposted by Paul & Virginie - Centriole Lab
'The Centre for Research in Cellular Biology of Montpellier (CRBM) is recruiting Junior/Senior Group Leaders to shape its research in the coming decade.
The deadline for application is 31st of March 2026.'
#sciencejobs
focalplane.biologists.com/cell-biology...
The deadline for application is 31st of March 2026.'
#sciencejobs
focalplane.biologists.com/cell-biology...
The Centre for Research in Cellular Biology of Montpellier (CRBM) is recruiting Junior / Senior Group Leaders - FocalPlane
The Centre for Research in Cellular Biology of Montpellier (CRBM) is recruiting Junior / Senior Group Leaders to shape its research in the coming decade
focalplane.biologists.com
February 4, 2026 at 11:52 AM
'The Centre for Research in Cellular Biology of Montpellier (CRBM) is recruiting Junior/Senior Group Leaders to shape its research in the coming decade.
The deadline for application is 31st of March 2026.'
#sciencejobs
focalplane.biologists.com/cell-biology...
The deadline for application is 31st of March 2026.'
#sciencejobs
focalplane.biologists.com/cell-biology...
Reposted by Paul & Virginie - Centriole Lab
📢 Happy to share our new preprint from @sophiemartinlab.bsky.social !
Check our latest work on cell–cell fusion, uncovering how PAK kinases promote cell-cell fusion irreversibility by preventing cell wall repair.
Check our latest work on cell–cell fusion, uncovering how PAK kinases promote cell-cell fusion irreversibility by preventing cell wall repair.
January 30, 2026 at 9:43 AM
📢 Happy to share our new preprint from @sophiemartinlab.bsky.social !
Check our latest work on cell–cell fusion, uncovering how PAK kinases promote cell-cell fusion irreversibility by preventing cell wall repair.
Check our latest work on cell–cell fusion, uncovering how PAK kinases promote cell-cell fusion irreversibility by preventing cell wall repair.
Reposted by Paul & Virginie - Centriole Lab
Please REPOST (“likes” don’t help in diffusion!) and consider applying: we work in such a fantastic context, we ask so interesting questions, and we have such a collegial and best-willing atmosphere… CRBM = Happy & Good Science
February 1, 2026 at 3:32 PM
Please REPOST (“likes” don’t help in diffusion!) and consider applying: we work in such a fantastic context, we ask so interesting questions, and we have such a collegial and best-willing atmosphere… CRBM = Happy & Good Science
Reposted by Paul & Virginie - Centriole Lab
Andreas #Boland's group and collaborators diagnosed a rare genetic disease (ATTR) using a simple skin biopsy. This work paves the way for new diagnostic methods for degenerative diseases. @mocel.bsky.social @sciencesunige.bsky.social @natcomms.nature.com www.unige.ch/medias/en/20...
January 27, 2026 at 7:13 AM
Andreas #Boland's group and collaborators diagnosed a rare genetic disease (ATTR) using a simple skin biopsy. This work paves the way for new diagnostic methods for degenerative diseases. @mocel.bsky.social @sciencesunige.bsky.social @natcomms.nature.com www.unige.ch/medias/en/20...
Reposted by Paul & Virginie - Centriole Lab
📣 Please spread: we’re hiring a Lab Manager! It is a critical position in our new lab. As our lab moves to Barcelona and joins the @crg.eu, we’re looking for a Lab Manager to help build the lab and set the lab atmosphere.
🔗 Apply here 👉 recruitment.crg.eu/content/jobs...
🔗 Apply here 👉 recruitment.crg.eu/content/jobs...
January 23, 2026 at 6:41 AM
📣 Please spread: we’re hiring a Lab Manager! It is a critical position in our new lab. As our lab moves to Barcelona and joins the @crg.eu, we’re looking for a Lab Manager to help build the lab and set the lab atmosphere.
🔗 Apply here 👉 recruitment.crg.eu/content/jobs...
🔗 Apply here 👉 recruitment.crg.eu/content/jobs...
Reposted by Paul & Virginie - Centriole Lab
Don't miss the spotlight that @hiralshah.bsky.social wrote :D
🔬🔦Our Imaging spotlight from @hiralshah.bsky.social & team highlights their U-ExM atlas of planktonic eukaryotes, including details on how you can explore this wonderful resource. Plus, check out Hiral’s top tips on getting started with expansion microscopy.
focalplane.biologists.com/2026/01/20/i...
focalplane.biologists.com/2026/01/20/i...
Imaging spotlight: U-ExM atlas of microbial eukaryotes - FocalPlane
Imaging spotlight: U-ExM atlas of microbial eukaryotes - News
focalplane.biologists.com
January 20, 2026 at 2:38 PM
Don't miss the spotlight that @hiralshah.bsky.social wrote :D
Reposted by Paul & Virginie - Centriole Lab
@marineluciano.bsky.social recreates intestinal Villi geometry by growing epithelial cells on wavy rolling substrates. Unexpected intrication of curvature effects is observed. Thanks to all! @caterinatomba.bsky.social @sgabriele.bsky.social @sciencesunige.bsky.social
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
January 20, 2026 at 10:24 AM
@marineluciano.bsky.social recreates intestinal Villi geometry by growing epithelial cells on wavy rolling substrates. Unexpected intrication of curvature effects is observed. Thanks to all! @caterinatomba.bsky.social @sgabriele.bsky.social @sciencesunige.bsky.social
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Reposted by Paul & Virginie - Centriole Lab
Presenting at the HFSP Awardees Meeting is more than a talk, it’s about exchanging ideas, cross-disciplinary feedback, and building new connections.
🧪 Call for Abstracts is open: zurl.co/AFFCZ
📍 Geneva, Switzerland
📅 8–10 July 2026
🗓 Deadline: 1 March 2026
#sts #HFSPmtg2026
🧪 Call for Abstracts is open: zurl.co/AFFCZ
📍 Geneva, Switzerland
📅 8–10 July 2026
🗓 Deadline: 1 March 2026
#sts #HFSPmtg2026
January 20, 2026 at 9:09 AM
Presenting at the HFSP Awardees Meeting is more than a talk, it’s about exchanging ideas, cross-disciplinary feedback, and building new connections.
🧪 Call for Abstracts is open: zurl.co/AFFCZ
📍 Geneva, Switzerland
📅 8–10 July 2026
🗓 Deadline: 1 March 2026
#sts #HFSPmtg2026
🧪 Call for Abstracts is open: zurl.co/AFFCZ
📍 Geneva, Switzerland
📅 8–10 July 2026
🗓 Deadline: 1 March 2026
#sts #HFSPmtg2026
Reposted by Paul & Virginie - Centriole Lab
🔬 Postdoc position – Infection Biology & Cryo-ET (Zurich) 🇨🇭
We are looking for a motivated Postdoc to join our interdisciplinary team.
📩 Interested? Check out the job advert:
www.imm.uzh.ch/dam/jcr:cb17...
👉 More info on the lab: www.weiss-laboratory.com
Please share with interested colleagues!
We are looking for a motivated Postdoc to join our interdisciplinary team.
📩 Interested? Check out the job advert:
www.imm.uzh.ch/dam/jcr:cb17...
👉 More info on the lab: www.weiss-laboratory.com
Please share with interested colleagues!
January 19, 2026 at 1:15 PM
🔬 Postdoc position – Infection Biology & Cryo-ET (Zurich) 🇨🇭
We are looking for a motivated Postdoc to join our interdisciplinary team.
📩 Interested? Check out the job advert:
www.imm.uzh.ch/dam/jcr:cb17...
👉 More info on the lab: www.weiss-laboratory.com
Please share with interested colleagues!
We are looking for a motivated Postdoc to join our interdisciplinary team.
📩 Interested? Check out the job advert:
www.imm.uzh.ch/dam/jcr:cb17...
👉 More info on the lab: www.weiss-laboratory.com
Please share with interested colleagues!
Reposted by Paul & Virginie - Centriole Lab
The EMBO Workshop "#Centrosomes: From fundamentals to diseases" in #Lausanne, Switzerland, 1–4 September 2026 will highlight the advances in the field of centrosome #research. Register now!
Deadline: 1 June
https://meetings.embo.org/event/26-centrosomes
#EMBOCentrosomes #EMBOevents #conference 🧪
Deadline: 1 June
https://meetings.embo.org/event/26-centrosomes
#EMBOCentrosomes #EMBOevents #conference 🧪
January 16, 2026 at 12:10 PM
The EMBO Workshop "#Centrosomes: From fundamentals to diseases" in #Lausanne, Switzerland, 1–4 September 2026 will highlight the advances in the field of centrosome #research. Register now!
Deadline: 1 June
https://meetings.embo.org/event/26-centrosomes
#EMBOCentrosomes #EMBOevents #conference 🧪
Deadline: 1 June
https://meetings.embo.org/event/26-centrosomes
#EMBOCentrosomes #EMBOevents #conference 🧪
Reposted by Paul & Virginie - Centriole Lab
Professor position in Global Health at the University of Geneva, Institute of Global Health!
This is really an exciting opportunity with lots of possibilities for collaborations, e.g. with our Centre, in the field of infectious diseases, international Geneva, WHO...
jobs.unige.ch/www/wd_porta...
This is really an exciting opportunity with lots of possibilities for collaborations, e.g. with our Centre, in the field of infectious diseases, international Geneva, WHO...
jobs.unige.ch/www/wd_porta...
Professeur-e ordinaire, professeur-e associé-e à l’Institut de santé globale (6726)
et affilié au Département de santé et médecine communautaires / Full professor or Associate professor at the Institute of Global Health and affiliated to the Department of Community Health and Medicin...
jobs.unige.ch
January 18, 2026 at 9:59 AM
Professor position in Global Health at the University of Geneva, Institute of Global Health!
This is really an exciting opportunity with lots of possibilities for collaborations, e.g. with our Centre, in the field of infectious diseases, international Geneva, WHO...
jobs.unige.ch/www/wd_porta...
This is really an exciting opportunity with lots of possibilities for collaborations, e.g. with our Centre, in the field of infectious diseases, international Geneva, WHO...
jobs.unige.ch/www/wd_porta...
Reposted by Paul & Virginie - Centriole Lab
Amazing to hold @lottepedersen.bsky.social & my @jcellsci.bsky.social Special Issue on #Cilia and #Flagella in all its glossy glory & muscle-engaging brain-boosting weight! So much fabulous content from the community! Fab cover @centriolelab.bsky.social 🥰🥰 journals.biologists.com/jcs/pages/ci...
January 16, 2026 at 7:30 PM
Amazing to hold @lottepedersen.bsky.social & my @jcellsci.bsky.social Special Issue on #Cilia and #Flagella in all its glossy glory & muscle-engaging brain-boosting weight! So much fabulous content from the community! Fab cover @centriolelab.bsky.social 🥰🥰 journals.biologists.com/jcs/pages/ci...
Reposted by Paul & Virginie - Centriole Lab
This is such hard news to process. Such an amazing scientist and inspiration for so many of us.
www.embl.org/news/embl-an...
www.embl.org/news/embl-an...
In remembrance of Peer Bork | EMBL
EMBL and its community are deeply saddened by the death of Peer Bork, the organisation’s Interim Director General.
www.embl.org
January 16, 2026 at 6:01 PM
This is such hard news to process. Such an amazing scientist and inspiration for so many of us.
www.embl.org/news/embl-an...
www.embl.org/news/embl-an...
Reposted by Paul & Virginie - Centriole Lab
📢 The Louis-Jeantet Foundation is happy to announce the 2026 #LouisJeantetPrizes, awarded to YASMINE BELKAID @pasteur.fr and to FIONA DOETSCH @doetschlab.bsky.social hlab.bsky.social @biozentrum.unibas.ch @unibas.ch
CONGRATULATIONS!!!
👉 jeantet.ch/en
👇 follow thread
CONGRATULATIONS!!!
👉 jeantet.ch/en
👇 follow thread
January 15, 2026 at 10:09 AM
📢 The Louis-Jeantet Foundation is happy to announce the 2026 #LouisJeantetPrizes, awarded to YASMINE BELKAID @pasteur.fr and to FIONA DOETSCH @doetschlab.bsky.social hlab.bsky.social @biozentrum.unibas.ch @unibas.ch
CONGRATULATIONS!!!
👉 jeantet.ch/en
👇 follow thread
CONGRATULATIONS!!!
👉 jeantet.ch/en
👇 follow thread
Reposted by Paul & Virginie - Centriole Lab
If you are interested in electron microscopy, registration is still open for the
"Electron Microscopy Hands-On Course: sample preparation and imaging of marine environmental samples"
at Stazione Zoologica in Naples.
WIth great teachers from Naples […]
[Original post on biologists.social]
"Electron Microscopy Hands-On Course: sample preparation and imaging of marine environmental samples"
at Stazione Zoologica in Naples.
WIth great teachers from Naples […]
[Original post on biologists.social]
January 13, 2026 at 7:08 AM
If you are interested in electron microscopy, registration is still open for the
"Electron Microscopy Hands-On Course: sample preparation and imaging of marine environmental samples"
at Stazione Zoologica in Naples.
WIth great teachers from Naples […]
[Original post on biologists.social]
"Electron Microscopy Hands-On Course: sample preparation and imaging of marine environmental samples"
at Stazione Zoologica in Naples.
WIth great teachers from Naples […]
[Original post on biologists.social]
Reposted by Paul & Virginie - Centriole Lab
New preprint from the lab 🎉: γ-tubulin is a novel target of the tubulin autoregulation pathway! Previously thought to exclusively target α- and β-tubulin mRNAs, we show that the TTC5–SCAPER–CNOT11 axis also degrades γ-tubulin mRNA, expanding the scope of this fundamental regulatory mechanism.
January 10, 2026 at 11:17 AM
New preprint from the lab 🎉: γ-tubulin is a novel target of the tubulin autoregulation pathway! Previously thought to exclusively target α- and β-tubulin mRNAs, we show that the TTC5–SCAPER–CNOT11 axis also degrades γ-tubulin mRNA, expanding the scope of this fundamental regulatory mechanism.
Reposted by Paul & Virginie - Centriole Lab
This is the cover proposal I made for our recent paper!
It’s Pyramimonas diskoicola — a very beautiful green flagellate and one of those cells that makes you stop and stare for a while.
I tried to capture its shape, symmetry, and general vibe :)
#FluorescenceFriday
#BioArt #SciArt
#Illustration
It’s Pyramimonas diskoicola — a very beautiful green flagellate and one of those cells that makes you stop and stare for a while.
I tried to capture its shape, symmetry, and general vibe :)
#FluorescenceFriday
#BioArt #SciArt
#Illustration
January 9, 2026 at 8:20 AM
This is the cover proposal I made for our recent paper!
It’s Pyramimonas diskoicola — a very beautiful green flagellate and one of those cells that makes you stop and stare for a while.
I tried to capture its shape, symmetry, and general vibe :)
#FluorescenceFriday
#BioArt #SciArt
#Illustration
It’s Pyramimonas diskoicola — a very beautiful green flagellate and one of those cells that makes you stop and stare for a while.
I tried to capture its shape, symmetry, and general vibe :)
#FluorescenceFriday
#BioArt #SciArt
#Illustration
If you’re looking to stain DNA in ExM and in particular U-ExM, Spirochrome offers a broad range of dyes that work really well 👍
Are you staining DNA in your ExM samples?
We have awesome news for you! All our 6 SPY-DNA probes work beautifully well with the U-ExM protocol.
You can now tune the color of the DNA channel to your needs, according to the fluorophores on your preferred antibodies.
spirochrome.com/products/?_c...
We have awesome news for you! All our 6 SPY-DNA probes work beautifully well with the U-ExM protocol.
You can now tune the color of the DNA channel to your needs, according to the fluorophores on your preferred antibodies.
spirochrome.com/products/?_c...
January 8, 2026 at 5:38 PM
If you’re looking to stain DNA in ExM and in particular U-ExM, Spirochrome offers a broad range of dyes that work really well 👍
Reposted by Paul & Virginie - Centriole Lab
Just over a week to our FIRST event for 2️⃣0️⃣2️⃣6️⃣- 13/01/2026 15:00-17:30 GMT. What better way to fire up those neural circuits than dipping into the latest breaking #Cilia and #Centrosome science 🧪? Free and open to everyone- /1
We must have been #ExtraNice this year- our #cilia & #centrosome 🧪 community- 🎅 Santa just dropped the 1st session of 2026 line-up @bscb-official.bsky.social @gensocuk.bsky.social @ukcilianetwork.bsky.social e-symposia- www.eventbrite.co.uk/e/bscb-genso... See you on the other side! Happy Holidays!
BSCB GenSoc UK Cilia and Centrosome Network e-Symposia Series
BSCB GenSoc UK Cilia and Centrosome Network e-Symposia Series
www.eventbrite.co.uk
January 5, 2026 at 5:29 PM
Just over a week to our FIRST event for 2️⃣0️⃣2️⃣6️⃣- 13/01/2026 15:00-17:30 GMT. What better way to fire up those neural circuits than dipping into the latest breaking #Cilia and #Centrosome science 🧪? Free and open to everyone- /1
Reposted by Paul & Virginie - Centriole Lab
Another #notTHECover unfortunately.
But this gorgeous, Tron-like vibe, drawn by the amazing @munafomarzia.bsky.social for our recent #ExM work with @gautamdey.bsky.social & @centriolelab.bsky.social will still be printed out in the lab.
Read here: www.cell.com/cell/fulltex...
But this gorgeous, Tron-like vibe, drawn by the amazing @munafomarzia.bsky.social for our recent #ExM work with @gautamdey.bsky.social & @centriolelab.bsky.social will still be printed out in the lab.
Read here: www.cell.com/cell/fulltex...
December 26, 2025 at 11:53 AM
Another #notTHECover unfortunately.
But this gorgeous, Tron-like vibe, drawn by the amazing @munafomarzia.bsky.social for our recent #ExM work with @gautamdey.bsky.social & @centriolelab.bsky.social will still be printed out in the lab.
Read here: www.cell.com/cell/fulltex...
But this gorgeous, Tron-like vibe, drawn by the amazing @munafomarzia.bsky.social for our recent #ExM work with @gautamdey.bsky.social & @centriolelab.bsky.social will still be printed out in the lab.
Read here: www.cell.com/cell/fulltex...
Reposted by Paul & Virginie - Centriole Lab
As a Christmas present, our Jove paper with @ebertiaux.bsky.social is out and available for everyone ! Check this out & thanks @centriolelab.bsky.social for the nice highlight
A super detailed protocol + video on Cryo-ExM - Cryo-Expansion Microscopy, led by the labs of our former postdocs @marinelap.bsky.social & @ebertiaux.bsky.social.
Clear, practical, and very useful for anyone doing nanoscale imaging 🚀 app.jove.com/t/68595/expa...
Clear, practical, and very useful for anyone doing nanoscale imaging 🚀 app.jove.com/t/68595/expa...
December 25, 2025 at 3:03 PM
As a Christmas present, our Jove paper with @ebertiaux.bsky.social is out and available for everyone ! Check this out & thanks @centriolelab.bsky.social for the nice highlight
A super detailed protocol + video on Cryo-ExM - Cryo-Expansion Microscopy, led by the labs of our former postdocs @marinelap.bsky.social & @ebertiaux.bsky.social.
Clear, practical, and very useful for anyone doing nanoscale imaging 🚀 app.jove.com/t/68595/expa...
Clear, practical, and very useful for anyone doing nanoscale imaging 🚀 app.jove.com/t/68595/expa...
December 25, 2025 at 1:41 PM
A super detailed protocol + video on Cryo-ExM - Cryo-Expansion Microscopy, led by the labs of our former postdocs @marinelap.bsky.social & @ebertiaux.bsky.social.
Clear, practical, and very useful for anyone doing nanoscale imaging 🚀 app.jove.com/t/68595/expa...
Clear, practical, and very useful for anyone doing nanoscale imaging 🚀 app.jove.com/t/68595/expa...
Reposted by Paul & Virginie - Centriole Lab
Tired of drawing cilia or centrioles for slides and papers? I feel you.
Check out CiliaBuilder for ChimeraX → cxtoolshed.rbvi.ucsf.edu/apps/chimera...
Build custom 3D cilia & centriole models (tips + primary cilia included).
Check out CiliaBuilder for ChimeraX → cxtoolshed.rbvi.ucsf.edu/apps/chimera...
Build custom 3D cilia & centriole models (tips + primary cilia included).
December 23, 2025 at 8:02 PM
Tired of drawing cilia or centrioles for slides and papers? I feel you.
Check out CiliaBuilder for ChimeraX → cxtoolshed.rbvi.ucsf.edu/apps/chimera...
Build custom 3D cilia & centriole models (tips + primary cilia included).
Check out CiliaBuilder for ChimeraX → cxtoolshed.rbvi.ucsf.edu/apps/chimera...
Build custom 3D cilia & centriole models (tips + primary cilia included).