Armando Rubio Ramos
@bioarm.bsky.social
Cell biologist 🔬 | Exploring the mysteries of centrosomes and cytoskeleton diversity🐉🦠 | Postdoc at Centriole Lab, University of Geneva
Pinned
Reposted by Armando Rubio Ramos
Thrilled to share the preprint from my PhD! 🥳 Where I characterised epithelial cell extrusion in a sea anemone
🔗 www.biorxiv.org/content/10.6...
Big thanks to my supervisor @prhsteinmetz.bsky.social and coauthors @noahbruderer.bsky.social @lionlchristiaen.bsky.social at🇳🇴 @msarscentre.bsky.social ⬇️🧵
🔗 www.biorxiv.org/content/10.6...
Big thanks to my supervisor @prhsteinmetz.bsky.social and coauthors @noahbruderer.bsky.social @lionlchristiaen.bsky.social at🇳🇴 @msarscentre.bsky.social ⬇️🧵
December 16, 2025 at 12:33 PM
Thrilled to share the preprint from my PhD! 🥳 Where I characterised epithelial cell extrusion in a sea anemone
🔗 www.biorxiv.org/content/10.6...
Big thanks to my supervisor @prhsteinmetz.bsky.social and coauthors @noahbruderer.bsky.social @lionlchristiaen.bsky.social at🇳🇴 @msarscentre.bsky.social ⬇️🧵
🔗 www.biorxiv.org/content/10.6...
Big thanks to my supervisor @prhsteinmetz.bsky.social and coauthors @noahbruderer.bsky.social @lionlchristiaen.bsky.social at🇳🇴 @msarscentre.bsky.social ⬇️🧵
Reposted by Armando Rubio Ramos
Tour de force #UExM study of #protist #cytoskeleton structures (>200 species🤯), led by @dudinlab.bsky.social, @gautamdey.bsky.social. A must for #tubulin & #centrin aficionados🤩
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Charting the landscape of cytoskeletal diversity in microbial eukaryotes
An imaging resource of over 200 microbial eukaryotic species provides a glimpse into
the remarkable universe of cytoskeletal diversity.
www.cell.com
December 25, 2025 at 5:11 PM
Tour de force #UExM study of #protist #cytoskeleton structures (>200 species🤯), led by @dudinlab.bsky.social, @gautamdey.bsky.social. A must for #tubulin & #centrin aficionados🤩
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
🧵 Cytoskeleton question of the day:
You want to localize your favourite protein.
What do you trust first?
🔹 GFP overexpression
🔹 CRISPR knock-in
🔹 Commercial Antibodies
🔹Homemade antibodies
🔹 Or “all of the above + controls” 👀
You want to localize your favourite protein.
What do you trust first?
🔹 GFP overexpression
🔹 CRISPR knock-in
🔹 Commercial Antibodies
🔹Homemade antibodies
🔹 Or “all of the above + controls” 👀
December 18, 2025 at 9:44 AM
🧵 Cytoskeleton question of the day:
You want to localize your favourite protein.
What do you trust first?
🔹 GFP overexpression
🔹 CRISPR knock-in
🔹 Commercial Antibodies
🔹Homemade antibodies
🔹 Or “all of the above + controls” 👀
You want to localize your favourite protein.
What do you trust first?
🔹 GFP overexpression
🔹 CRISPR knock-in
🔹 Commercial Antibodies
🔹Homemade antibodies
🔹 Or “all of the above + controls” 👀
Christmas party of the centriole lab - December 2075
Christmas party 🎄- The lab went full senior mode (and won the best costume). You all rock 😄 !!!!!! (If you’re wondering where the youth went… check who’s been quietly draining the lab’s energy 😈)
December 13, 2025 at 12:30 PM
Christmas party of the centriole lab - December 2075
Reposted by Armando Rubio Ramos
Delighted to share our latest preprint on reverse gyrase, a unique topoisomerase found exclusively in thermophiles!
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Reverse gyrase and 3D genome architecture suppress hyperthermophile genome instability arising from horizontal gene transfer
Reverse gyrase (Rgy), a distinctive topoisomerase conserved in all hyperthermophiles, has the unique ability to introduce positive DNA supercoils. It has long been hypothesized that Rgy overwinds geno...
www.biorxiv.org
December 11, 2025 at 6:40 AM
Delighted to share our latest preprint on reverse gyrase, a unique topoisomerase found exclusively in thermophiles!
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Reposted by Armando Rubio Ramos
Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1...
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
August 28, 2025 at 7:03 AM
Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1...
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
'Cum hoc ergo propter hoc'
Correlation does not imply causation.
Here a 'sequence' of 3 nuclei that of U2OS cells
#FluorescenceFriday
#Microscopy
#Expansion
Correlation does not imply causation.
Here a 'sequence' of 3 nuclei that of U2OS cells
#FluorescenceFriday
#Microscopy
#Expansion
December 10, 2025 at 4:18 PM
'Cum hoc ergo propter hoc'
Correlation does not imply causation.
Here a 'sequence' of 3 nuclei that of U2OS cells
#FluorescenceFriday
#Microscopy
#Expansion
Correlation does not imply causation.
Here a 'sequence' of 3 nuclei that of U2OS cells
#FluorescenceFriday
#Microscopy
#Expansion
Reposted by Armando Rubio Ramos
Thrilled to share that my postdoc paper has just been a published in @plosbiology.org !
Thank you to all co-authors, and a special thanks to Paul and Virginie @centriolelab.bsky.social for their support throughout this work.
Proud of what we achieved together!
journals.plos.org/plosbiology/...
Thank you to all co-authors, and a special thanks to Paul and Virginie @centriolelab.bsky.social for their support throughout this work.
Proud of what we achieved together!
journals.plos.org/plosbiology/...
The luminal ring protein C2CD3 acts as a radial in-to-out organizer of the distal centriole and appendages
The centriolar protein C2CD3 has been suggested to be crucial for distal appendage formation in centrioles, but its precise mechanistic role remains unclear. Using a combination of ultrastructure expa...
journals.plos.org
December 10, 2025 at 8:29 AM
Thrilled to share that my postdoc paper has just been a published in @plosbiology.org !
Thank you to all co-authors, and a special thanks to Paul and Virginie @centriolelab.bsky.social for their support throughout this work.
Proud of what we achieved together!
journals.plos.org/plosbiology/...
Thank you to all co-authors, and a special thanks to Paul and Virginie @centriolelab.bsky.social for their support throughout this work.
Proud of what we achieved together!
journals.plos.org/plosbiology/...
Reposted by Armando Rubio Ramos
After years of struggling with how to cryopreserve one of our endosymbiotic bacteria, we found something that worked!
🦠☃️
We crowd-sourced suggestions and then @ruthwright.bsky.social tried the most common ones (like 🥛...). Want to do the same? Here is how we did it:
www.biorxiv.org/content/10.6...
🦠☃️
We crowd-sourced suggestions and then @ruthwright.bsky.social tried the most common ones (like 🥛...). Want to do the same? Here is how we did it:
www.biorxiv.org/content/10.6...
Identifying Effective Cryoprotectant Agents for Emerging Bacterial Model Species
Host-associated bacteria live amongst eukaryotes within varied niches and form relationships ranging from facultative to obligate. With advancement in studies of such symbiotic associations, fastidiou...
www.biorxiv.org
December 8, 2025 at 3:25 PM
After years of struggling with how to cryopreserve one of our endosymbiotic bacteria, we found something that worked!
🦠☃️
We crowd-sourced suggestions and then @ruthwright.bsky.social tried the most common ones (like 🥛...). Want to do the same? Here is how we did it:
www.biorxiv.org/content/10.6...
🦠☃️
We crowd-sourced suggestions and then @ruthwright.bsky.social tried the most common ones (like 🥛...). Want to do the same? Here is how we did it:
www.biorxiv.org/content/10.6...
Reposted by Armando Rubio Ramos
Heading to #CellBio2025 @ascbiology.bsky.social @embo.org?
Stop by my poster P0101 tomorrow (Sun, 12:45 PM) in the session “Cytoskeleton and Motility-Microtubule Organization and Dynamics”.
Looking forward to lively discussions on tubulin regulation & microtubule organization. See you in Philly!
Stop by my poster P0101 tomorrow (Sun, 12:45 PM) in the session “Cytoskeleton and Motility-Microtubule Organization and Dynamics”.
Looking forward to lively discussions on tubulin regulation & microtubule organization. See you in Philly!
December 6, 2025 at 8:44 AM
Heading to #CellBio2025 @ascbiology.bsky.social @embo.org?
Stop by my poster P0101 tomorrow (Sun, 12:45 PM) in the session “Cytoskeleton and Motility-Microtubule Organization and Dynamics”.
Looking forward to lively discussions on tubulin regulation & microtubule organization. See you in Philly!
Stop by my poster P0101 tomorrow (Sun, 12:45 PM) in the session “Cytoskeleton and Motility-Microtubule Organization and Dynamics”.
Looking forward to lively discussions on tubulin regulation & microtubule organization. See you in Philly!
Reposted by Armando Rubio Ramos
Interested in applying U-ExM to cells, tissues, organoids, or cryo-sections? Our EMBO workshop is open for applications!
🧫🔬 Deadline: 12 Jan 2026 — don’t miss it!
🧫🔬 Deadline: 12 Jan 2026 — don’t miss it!
Have you applied for 'Ultrastructure expansion microscopy: from cells to tissue' yet? #EMBOExM
🔬 Advance your microscopy skills by joining us to explore U-ExM techniques and gain hands-on expertise in applying this powerful approach to mammalian cells.
Apply now: s.embl.org/uex26-01-bl
🔬 Advance your microscopy skills by joining us to explore U-ExM techniques and gain hands-on expertise in applying this powerful approach to mammalian cells.
Apply now: s.embl.org/uex26-01-bl
December 2, 2025 at 3:13 PM
Interested in applying U-ExM to cells, tissues, organoids, or cryo-sections? Our EMBO workshop is open for applications!
🧫🔬 Deadline: 12 Jan 2026 — don’t miss it!
🧫🔬 Deadline: 12 Jan 2026 — don’t miss it!
Reposted by Armando Rubio Ramos
New paper from the @rouxlab.bsky.social on Nature Communications! We study how membrane tension is spatially organized in cells. Using the mechanosensitive probe Flipper-TR to visualize tension across the plasma membrane of adherent cells and to dissect the conditions needed for a gradient to happen
November 27, 2025 at 2:14 PM
New paper from the @rouxlab.bsky.social on Nature Communications! We study how membrane tension is spatially organized in cells. Using the mechanosensitive probe Flipper-TR to visualize tension across the plasma membrane of adherent cells and to dissect the conditions needed for a gradient to happen
Reposted by Armando Rubio Ramos
Just uploaded our new preprint to @ecoevorxiv.bsky.social
Multinucleate life really is everywhere...from deep sea forams to slime molds, intracellular parasites, and beyond. 🚀
We explore how scaling, ecology, & evolution intersect when many nuclei share a single cytoplasm.
doi.org/10.32942/X2M...
Multinucleate life really is everywhere...from deep sea forams to slime molds, intracellular parasites, and beyond. 🚀
We explore how scaling, ecology, & evolution intersect when many nuclei share a single cytoplasm.
doi.org/10.32942/X2M...
November 26, 2025 at 3:06 PM
Just uploaded our new preprint to @ecoevorxiv.bsky.social
Multinucleate life really is everywhere...from deep sea forams to slime molds, intracellular parasites, and beyond. 🚀
We explore how scaling, ecology, & evolution intersect when many nuclei share a single cytoplasm.
doi.org/10.32942/X2M...
Multinucleate life really is everywhere...from deep sea forams to slime molds, intracellular parasites, and beyond. 🚀
We explore how scaling, ecology, & evolution intersect when many nuclei share a single cytoplasm.
doi.org/10.32942/X2M...
Reposted by Armando Rubio Ramos
Grants writing tips: (1) Rejections are totally normal, have faith in your idea, push it and improve it; (2) Every panel is different. Study it and prepare your grant for them; (3) Grant-writing takes months. Plan it and get diverse feedback and (4) Have fun with it! The work there is never wasted 😜
November 26, 2025 at 3:53 PM
Grants writing tips: (1) Rejections are totally normal, have faith in your idea, push it and improve it; (2) Every panel is different. Study it and prepare your grant for them; (3) Grant-writing takes months. Plan it and get diverse feedback and (4) Have fun with it! The work there is never wasted 😜
Reposted by Armando Rubio Ramos
In 2023, we first sampled from a geothermal tributary at LVNP and using enrichment culturing, found an amoeba growing at high temp.
November 25, 2025 at 8:22 PM
In 2023, we first sampled from a geothermal tributary at LVNP and using enrichment culturing, found an amoeba growing at high temp.
Reposted by Armando Rubio Ramos
The lab’s first pre-print! We investigated how growth-inducing Erk activity waves are regulated in regenerating zebrafish scales. We discovered that Erk waves are followed by waves of expression of their own inhibitors, as predicted by excitable waves theory. tinyurl.com/26r2cmpj
November 20, 2025 at 6:11 PM
The lab’s first pre-print! We investigated how growth-inducing Erk activity waves are regulated in regenerating zebrafish scales. We discovered that Erk waves are followed by waves of expression of their own inhibitors, as predicted by excitable waves theory. tinyurl.com/26r2cmpj
Reposted by Armando Rubio Ramos
An interesting essay by Oliver Hobert on 'Paraneurons':
"unifying sensory receptors
located on external or internal epithelial
cells feeding into the nervous system,
as well as effector cells of the nervous
system that respond to neuronal
stimuli by […]
[Original post on biologists.social]
"unifying sensory receptors
located on external or internal epithelial
cells feeding into the nervous system,
as well as effector cells of the nervous
system that respond to neuronal
stimuli by […]
[Original post on biologists.social]
November 19, 2025 at 8:12 AM
An interesting essay by Oliver Hobert on 'Paraneurons':
"unifying sensory receptors
located on external or internal epithelial
cells feeding into the nervous system,
as well as effector cells of the nervous
system that respond to neuronal
stimuli by […]
[Original post on biologists.social]
"unifying sensory receptors
located on external or internal epithelial
cells feeding into the nervous system,
as well as effector cells of the nervous
system that respond to neuronal
stimuli by […]
[Original post on biologists.social]
Reposted by Armando Rubio Ramos
Congratulations @centriolelab.bsky.social @dudinlab.bsky.social and @gautamdey.bsky.social for your publication in @cp-cell.bsky.social: Charting the landscape of #cytoskeletal diversity in #microbial eukaryotes #Expansion #Microscopy @sciencesunige.bsky.social
www.unige.ch/medias/en/20...
Congratulations @centriolelab.bsky.social @dudinlab.bsky.social and @gautamdey.bsky.social for your publication in @cp-cell.bsky.social: Charting the landscape of #cytoskeletal diversity in #microbial eukaryotes #Expansion #Microscopy @sciencesunige.bsky.social
www.unige.ch/medias/en/20...
November 3, 2025 at 1:34 PM
Congratulations @centriolelab.bsky.social @dudinlab.bsky.social and @gautamdey.bsky.social for your publication in @cp-cell.bsky.social: Charting the landscape of #cytoskeletal diversity in #microbial eukaryotes #Expansion #Microscopy @sciencesunige.bsky.social
www.unige.ch/medias/en/20...
Congratulations @centriolelab.bsky.social @dudinlab.bsky.social and @gautamdey.bsky.social for your publication in @cp-cell.bsky.social: Charting the landscape of #cytoskeletal diversity in #microbial eukaryotes #Expansion #Microscopy @sciencesunige.bsky.social
www.unige.ch/medias/en/20...
Reposted by Armando Rubio Ramos
Our study, just published in #ScienceAdvances and funded by @hfspo.bsky.social, explores the post metamorphic cell composition of the sea urchin juvenile, revealing that its body is head-like. Long considered brainless creatures, they’re all brain instead!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Single-nucleus profiling highlights the all-brain echinoderm nervous system
A sea urchin is a head with a brain-like organization and a vertebrate-type retinal signature.
www.science.org
November 5, 2025 at 7:03 PM
Our study, just published in #ScienceAdvances and funded by @hfspo.bsky.social, explores the post metamorphic cell composition of the sea urchin juvenile, revealing that its body is head-like. Long considered brainless creatures, they’re all brain instead!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Armando Rubio Ramos
Mammalian cells have KSR, budding yeast has Ste5… and fission yeast has Sms1 as the MAPK scaffold for sexual reproduction!
Very excited to share my postdoc work where we discover that the hemi-arrestin Sms1 binds all components of the MAPK cascade, including ERK-like Spk1
doi.org/10.1101/2025...
Very excited to share my postdoc work where we discover that the hemi-arrestin Sms1 binds all components of the MAPK cascade, including ERK-like Spk1
doi.org/10.1101/2025...
September 25, 2025 at 4:27 PM
Mammalian cells have KSR, budding yeast has Ste5… and fission yeast has Sms1 as the MAPK scaffold for sexual reproduction!
Very excited to share my postdoc work where we discover that the hemi-arrestin Sms1 binds all components of the MAPK cascade, including ERK-like Spk1
doi.org/10.1101/2025...
Very excited to share my postdoc work where we discover that the hemi-arrestin Sms1 binds all components of the MAPK cascade, including ERK-like Spk1
doi.org/10.1101/2025...
Me describing my grant idea to my fellas: A masterpiece of logic and innovation VS
Me actually writing it at 2 AM: Chaos and disillusion
Me actually writing it at 2 AM: Chaos and disillusion
November 16, 2025 at 11:41 AM
Me describing my grant idea to my fellas: A masterpiece of logic and innovation VS
Me actually writing it at 2 AM: Chaos and disillusion
Me actually writing it at 2 AM: Chaos and disillusion
Reposted by Armando Rubio Ramos
Happy to share our manuscript on the in situ visualization of the copia retrotransposon in its final form today published in @cellcellpress.bsky.social www.cell.com/cell/fulltex.... What’s new?
March 5, 2025 at 4:02 PM
Happy to share our manuscript on the in situ visualization of the copia retrotransposon in its final form today published in @cellcellpress.bsky.social www.cell.com/cell/fulltex.... What’s new?
Reposted by Armando Rubio Ramos
Launching celldynamicslab.com, the homepage of our new group at EPFL working on cell fragmentation, membrane and cortex mechanics, FLIM imaging, and microfluidics tools. MSc/PhD or postdocs interested in quantitative cell biology are welcome to reach out. We're also hiring a lab manager in 2026!
Main - Cell Dynamics and Fragmentation Lab
The Cell Dynamics and Fragmentation lab at We study how single cells move and fragment in complex environments using microfluidics. We bring tools and concep...
celldynamicslab.com
November 11, 2025 at 5:10 PM
Launching celldynamicslab.com, the homepage of our new group at EPFL working on cell fragmentation, membrane and cortex mechanics, FLIM imaging, and microfluidics tools. MSc/PhD or postdocs interested in quantitative cell biology are welcome to reach out. We're also hiring a lab manager in 2026!
Check this one out! Outstanding review to understand all the different approaches that are being used to understand the structure and function of the Cilia and the centriole :)
#cytoskeleton #cellbiology
PS: and congrats for the cover🥰
#cytoskeleton #cellbiology
PS: and congrats for the cover🥰
Exciting news: the new review from @centriolelab.bsky.social is out in the amazing #JCSciliaSI! 🎉
I had the pleasure of working alongside Olivier Mercey, Paul Guichard and Virginie Hamel on this one.
Cherry on top: our #UExM image was selected for the cover of the issue! 🤩
I had the pleasure of working alongside Olivier Mercey, Paul Guichard and Virginie Hamel on this one.
Cherry on top: our #UExM image was selected for the cover of the issue! 🤩
Advances in high-resolution imaging of centrioles and cilia
Summary: A review of the progressive advances in light and electron microscopy that have revealed unprecedented structural and molecular insights into centrioles and cilia, and reshaped our view of th...
journals.biologists.com
November 11, 2025 at 3:11 PM
Check this one out! Outstanding review to understand all the different approaches that are being used to understand the structure and function of the Cilia and the centriole :)
#cytoskeleton #cellbiology
PS: and congrats for the cover🥰
#cytoskeleton #cellbiology
PS: and congrats for the cover🥰
Reposted by Armando Rubio Ramos
