Arnone Lab
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arnonelab.bsky.social
Arnone Lab
@arnonelab.bsky.social
Group established in 2000, studying Echinoderms to unravel the evolution of organs and body parts by comparison of gene regulatory networks. https://arnonelab.it/
Pinned
Exciting news to start the new year! We’re thrilled to see this work finally out in @natecoevo.nature.com, the result of a major collaboration between my lab and the labs of Veronica Hinman and Nacho Maeso, began many years ago with the dear José Luis Gómez-Skarmeta.
www.nature.com/articles/s41...
Reposted by Arnone Lab
There are just a few days (and spots!) left to apply to this EM course with a focus on marine samples 🌊 do not miss it!
Don’t forget to apply to this beautiful Electron Microscopy course at @szndohrn.bsky.social in Napoli, Italy by February 12th! 🌊 ☀️ Stay tuned for the preliminary program, in the meantime take a look here: www.szn.it/index.php/it...
February 9, 2026 at 2:49 PM
Reposted by Arnone Lab
We are excited to share that we are hosting a hands-on course on "Electron Microscopy of Marine Environmental Samples" 🔬🌊
📍Naples, Italy 🗓️ 8th-11th of April 2026
If you are interested, check the program below!
Registration is open until the 12th of February. We look forward to seeing you there!
January 20, 2026 at 4:32 PM
New findings on genomic regulation mechanisms throughout evolution | EurekAlert! www.eurekalert.org/news-release...
New findings on genomic regulation mechanisms throughout evolution
The conservation of genome regulatory elements over long periods of evolution is not limited to vertebrates, as previously thought, but also in echinoderms (invertebrates). This is one of the most not...
www.eurekalert.org
January 15, 2026 at 9:39 AM
Reposted by Arnone Lab
EMHOC’s preliminary program is out. Check it out to stay updated!
EMHOC 2026 preliminary program
EMHOC 2026 Preliminary Program Day 1 - Wednesday, April 8th 13h00 - 14h00 Arrival and registration 14h00 - 14h15 Welcome and introduction to the course Giovanna Benvenuto, Stazione Zoologica Napoli, ...
docs.google.com
January 12, 2026 at 11:06 AM
Reposted by Arnone Lab
Our work on the evolution of the regulatory genome of echinoderms is now out in @natecoevo.nature.com. Led by my former PhD Marta Magri, Danila Voronov & Saoirse Foley. Great collaboration of Arnone, Hinman & Maeso labs, started long time ago with our missed José Luis Gomez-Skarmeta: rdcu.be/eXX8l
Deep conservation of cis-regulatory elements and chromatin organization in echinoderms uncover ancestral regulatory features of animal genomes
Nature Ecology & Evolution - Analysis of the 3D chromatin architecture and cis-regulatory elements in a sea urchin and a sea star reveals mechanisms of 3D chromatin organization in echinoderms...
rdcu.be
January 7, 2026 at 7:33 PM
Reposted by Arnone Lab
I am extremely proud and happy to announce that another paper from my PhD days has just been published in @natecoevo.nature.com on evolution of genome and gene regulation thanks to all the amazing people involved.

Check the paper out at:
www.nature.com/articles/s41...
Deep conservation of cis-regulatory elements and chromatin organization in echinoderms uncover ancestral regulatory features of animal genomes - Nature Ecology & Evolution
Analysis of the 3D chromatin architecture and cis-regulatory elements in a sea urchin and a sea star reveals mechanisms of 3D chromatin organization in echinoderms and the long-term evolutionary dynam...
www.nature.com
January 7, 2026 at 12:08 PM
Thanks to everybody involved, especially my former and present lab members: @danivoronov.bsky.social, @perievodevo.bsky.social, @mlrusciano.bsky.social, Claudia Cuomo, Jovana Ranđelović.
January 7, 2026 at 10:44 AM
We here present two new genome assemblies for S. purpuratus and P. miniata, showing they are organized in TAD-like structures that, unlike vertebrates, are not built with CTCF. We also found deeply conserved cis-regulatory modules such as the one upstream of Tbx2/3, and we functionally evaluated it.
January 7, 2026 at 10:43 AM
In this work, we present Echinoderms as a paradigm to understand how genome organization shapes organismal body plans and their evolution.
January 7, 2026 at 10:43 AM
Exciting news to start the new year! We’re thrilled to see this work finally out in @natecoevo.nature.com, the result of a major collaboration between my lab and the labs of Veronica Hinman and Nacho Maeso, began many years ago with the dear José Luis Gómez-Skarmeta.
www.nature.com/articles/s41...
January 7, 2026 at 10:17 AM
Reposted by Arnone Lab
Don’t forget to apply to this beautiful Electron Microscopy course at @szndohrn.bsky.social in Napoli, Italy by February 12th! 🌊 ☀️ Stay tuned for the preliminary program, in the meantime take a look here: www.szn.it/index.php/it...
January 5, 2026 at 7:10 PM
Thank you!
January 3, 2026 at 5:28 PM
These are the objectives we will pursue in NeurEvoFun (“Dissecting the neurosecretory brain-gut axis function and evolution: from regulome and cell identity to cellular crosstalk”).
January 3, 2026 at 3:18 PM
I am deeply honored to share that my project NeurEvoFun has been awarded support from the Fondo Italiano per la Scienza (FIS), the Advanced Grant by the Italian Ministry of Education, Universities and Research, supporting fundamental research inspired by the ERC model. Excited for what’s ahead!
January 3, 2026 at 10:24 AM
Beautiful course on electron microscopy coming soon in Naples, do not miss it!
The "Electron Microscopy Hands-On Course" returns for its 2nd edition in April 8-11, 2026, at the Stazione Zoologica Anton Dohrn in Naples, Italy. Explore the course overview and start your application here:
www.szn.it/index.php/it...
December 15, 2025 at 8:14 PM
What a nice way to end the year - last shift of 2025 on the EMBL beamline P14 on Petra III in Hamburg! With @mlrusciano.bsky.social we did x-ray imaging of sea urchin larvae and had the honor of using the synchrotron ourselves! Many thanks to Angelika Svetlove. @embl.org
December 12, 2025 at 4:58 PM
Reposted by Arnone Lab
In preprints: cell type-specific gene regulation through the lens of echinoderms

Periklis Paganos and @arnonelab.bsky.social discuss a recent #preprint by Jonas Maurice Brandenburg, David Aaron Garfield and colleagues

doi.org/10.1242/dev....
November 18, 2025 at 3:06 PM
Thank you, Filippo!
November 6, 2025 at 6:50 PM
Thank you!
November 5, 2025 at 9:50 PM
In collaboration with @mfnberlin.bsky.social, Jack Ullrich-Lüter, Jil Carl, Anne-C. Zakrzewski, Berit Zemann, Carsten Lüter, @biodev-vlfr.bsky.social @croce-urchin.bsky.social, Tiphaine Sancerni, Maria Schauer, Oğuz Akar, @igflyon.bsky.social, @almazan.bsky.social. Thank you, all!
November 5, 2025 at 7:06 PM
November 5, 2025 at 7:05 PM
We report high expression of vertebrates’ brain and retina genes, and a vast array of photoreceptor cells. Among those, we detect cells that express a rare combination of opsins, perhaps an ideal candidate for non-ocular vision. 👀 #ScienceAdvancesResearch @szndohrn.bsky.social @science.org
November 5, 2025 at 7:04 PM