Marine Laporte
@marinelap.bsky.social
Researcher in MeLiS - Lyon. Likes centrioles, cilia and anything graviting around those
Reposted by Marine Laporte
🚨Our collaboration with @centriolelab.bsky.social & @gautamdey.bsky.social is out today in @cp-cell.bsky.social
We show that #Expansion #Microscopy is a broad-spectrum modality for Euks, enabling 3D phenotypic maps rooted to phylogeny.
#ProtistsOnSky #SciComm #SciSky
www.cell.com/cell/fulltex...
We show that #Expansion #Microscopy is a broad-spectrum modality for Euks, enabling 3D phenotypic maps rooted to phylogeny.
#ProtistsOnSky #SciComm #SciSky
www.cell.com/cell/fulltex...
October 31, 2025 at 2:42 PM
🚨Our collaboration with @centriolelab.bsky.social & @gautamdey.bsky.social is out today in @cp-cell.bsky.social
We show that #Expansion #Microscopy is a broad-spectrum modality for Euks, enabling 3D phenotypic maps rooted to phylogeny.
#ProtistsOnSky #SciComm #SciSky
www.cell.com/cell/fulltex...
We show that #Expansion #Microscopy is a broad-spectrum modality for Euks, enabling 3D phenotypic maps rooted to phylogeny.
#ProtistsOnSky #SciComm #SciSky
www.cell.com/cell/fulltex...
Reposted by Marine Laporte
Calling all #Membrane enthusiasts!
Our #MembraneTrafficking online seminar series is back for the 2025-26 season: 8 fantastic speakers from Nov'25 to Feb'26.
The first talks are already next Thursday (Nov 6, 5pm CET) with @agatawitkowska.bsky.social and @abdourachidthiam.bsky.social !
Our #MembraneTrafficking online seminar series is back for the 2025-26 season: 8 fantastic speakers from Nov'25 to Feb'26.
The first talks are already next Thursday (Nov 6, 5pm CET) with @agatawitkowska.bsky.social and @abdourachidthiam.bsky.social !
October 27, 2025 at 5:02 PM
Calling all #Membrane enthusiasts!
Our #MembraneTrafficking online seminar series is back for the 2025-26 season: 8 fantastic speakers from Nov'25 to Feb'26.
The first talks are already next Thursday (Nov 6, 5pm CET) with @agatawitkowska.bsky.social and @abdourachidthiam.bsky.social !
Our #MembraneTrafficking online seminar series is back for the 2025-26 season: 8 fantastic speakers from Nov'25 to Feb'26.
The first talks are already next Thursday (Nov 6, 5pm CET) with @agatawitkowska.bsky.social and @abdourachidthiam.bsky.social !
Reposted by Marine Laporte
The ExM gang @jvermot.bsky.social @mahjoublab.bsky.social @marinelap.bsky.social @centriolelab.bsky.social @simonemortal.bsky.social et al #GEF25
September 29, 2025 at 8:04 PM
Reposted by Marine Laporte
Now out on bioRxiv. 🥳My research on #cytokinesis, averaging thousands of #ExM images🔬, creating a dynamic atlas of cytokinesis 🦠⏳. Here's an animated sneak peek of what we found. Better resolution on bioRxiv😄 #PSFoftheGIF
September 28, 2025 at 2:15 PM
Now out on bioRxiv. 🥳My research on #cytokinesis, averaging thousands of #ExM images🔬, creating a dynamic atlas of cytokinesis 🦠⏳. Here's an animated sneak peek of what we found. Better resolution on bioRxiv😄 #PSFoftheGIF
Reposted by Marine Laporte
Check the live stream of the Göttingen Expansion Forum 2025 if you're interested! I think the link changes every day will try to update. Program is here (pdf link): www.rizzoli-lab.de/wp-content/u...
September 28, 2025 at 8:52 AM
Check the live stream of the Göttingen Expansion Forum 2025 if you're interested! I think the link changes every day will try to update. Program is here (pdf link): www.rizzoli-lab.de/wp-content/u...
Reposted by Marine Laporte
#ExM turned 10 this year - just like #NanoTag! 🎉
Join us & the super-resolution community in Göttingen for the ExM Forum! 🔬Hear from our founder Felipe Opazo @opazo.bsky.social and CSO Steffen Frey on how NanoTag’s sdAb solutions empower nanoscopy & #multiplex imaging.
See you in Göttingen!
#GEF25
Join us & the super-resolution community in Göttingen for the ExM Forum! 🔬Hear from our founder Felipe Opazo @opazo.bsky.social and CSO Steffen Frey on how NanoTag’s sdAb solutions empower nanoscopy & #multiplex imaging.
See you in Göttingen!
#GEF25
September 17, 2025 at 8:33 AM
#ExM turned 10 this year - just like #NanoTag! 🎉
Join us & the super-resolution community in Göttingen for the ExM Forum! 🔬Hear from our founder Felipe Opazo @opazo.bsky.social and CSO Steffen Frey on how NanoTag’s sdAb solutions empower nanoscopy & #multiplex imaging.
See you in Göttingen!
#GEF25
Join us & the super-resolution community in Göttingen for the ExM Forum! 🔬Hear from our founder Felipe Opazo @opazo.bsky.social and CSO Steffen Frey on how NanoTag’s sdAb solutions empower nanoscopy & #multiplex imaging.
See you in Göttingen!
#GEF25
Reposted by Marine Laporte
Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1...
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
August 28, 2025 at 7:03 AM
Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1...
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
Reposted by Marine Laporte
🚨
New Preprint!
Ex-dSTORM resolves fine details of the molecular architecture of CCPs, the 8-nm periodicity of microtubules, and the docking site of synaptic vesicles at the presynapse of hippocampal neurons.
▶️ www.biorxiv.org/content/10.1...
New Preprint!
Ex-dSTORM resolves fine details of the molecular architecture of CCPs, the 8-nm periodicity of microtubules, and the docking site of synaptic vesicles at the presynapse of hippocampal neurons.
▶️ www.biorxiv.org/content/10.1...
August 19, 2025 at 3:32 PM
🚨
New Preprint!
Ex-dSTORM resolves fine details of the molecular architecture of CCPs, the 8-nm periodicity of microtubules, and the docking site of synaptic vesicles at the presynapse of hippocampal neurons.
▶️ www.biorxiv.org/content/10.1...
New Preprint!
Ex-dSTORM resolves fine details of the molecular architecture of CCPs, the 8-nm periodicity of microtubules, and the docking site of synaptic vesicles at the presynapse of hippocampal neurons.
▶️ www.biorxiv.org/content/10.1...
Reposted by Marine Laporte
With a combination of FIB-SEM, super-resolution & expansion #microscopy, Araujo Alves, Bastin et al @bastinlab.bsky.social @pasteur.fr reveal how IFT trains are progressively restricted to a limited number of #microtubule doublets in the flagellum of T. brucei. rupress.org/jcb/article/...
#Cilia
#Cilia
August 13, 2025 at 4:15 PM
With a combination of FIB-SEM, super-resolution & expansion #microscopy, Araujo Alves, Bastin et al @bastinlab.bsky.social @pasteur.fr reveal how IFT trains are progressively restricted to a limited number of #microtubule doublets in the flagellum of T. brucei. rupress.org/jcb/article/...
#Cilia
#Cilia
Reposted by Marine Laporte
⏰ One week countdown- 19/08/2025 15:00 BST we kick off our 52nd BSCB GenSoc UK Cilia and Centrosome Network e-symposium with 6 stellar talks from the field's rising stars 🌠 on the latest breaking science 🧪!!
FOMO? Join the fun: www.eventbrite.co.uk/e/bscb-genso...
FOMO? Join the fun: www.eventbrite.co.uk/e/bscb-genso...
We have something for everyone- CSF flow & #neurodegeneration, ciliary trafficking of PKD2 complexes, cilia & #actin dynamics, #DNADamageResponse & multiciliation, cilia & pituitary development & transcriptional control of ciliogenesis... Great breaking science & rising talent to be showcased...🧪
August 12, 2025 at 6:38 AM
⏰ One week countdown- 19/08/2025 15:00 BST we kick off our 52nd BSCB GenSoc UK Cilia and Centrosome Network e-symposium with 6 stellar talks from the field's rising stars 🌠 on the latest breaking science 🧪!!
FOMO? Join the fun: www.eventbrite.co.uk/e/bscb-genso...
FOMO? Join the fun: www.eventbrite.co.uk/e/bscb-genso...
Reposted by Marine Laporte
Reposted by Marine Laporte
Publications scientifiques - Club Exo Endo - Exocytose Endocytose
exoendo.org
August 1, 2025 at 12:10 PM
Reposted by Marine Laporte
🎉Excited to see my master’s work contributed to this amazing paper! 🎥 🧠
Congrats to all co-authors 👏
Grateful for my time in Dr. Isabelle Caillé & Pr. Alain Trembleau’s lab #IBPS. Isabelle’s passion for science will keep inspiring me ✨
doi.org/10.1126/scia...
Congrats to all co-authors 👏
Grateful for my time in Dr. Isabelle Caillé & Pr. Alain Trembleau’s lab #IBPS. Isabelle’s passion for science will keep inspiring me ✨
doi.org/10.1126/scia...
GPR161 mechanosensitivity at the primary cilium drives neuronal saltatory migration
Primary cilium senses mechanical cues to regulate young neuron migration via GPR161 signaling.
doi.org
July 31, 2025 at 4:08 PM
🎉Excited to see my master’s work contributed to this amazing paper! 🎥 🧠
Congrats to all co-authors 👏
Grateful for my time in Dr. Isabelle Caillé & Pr. Alain Trembleau’s lab #IBPS. Isabelle’s passion for science will keep inspiring me ✨
doi.org/10.1126/scia...
Congrats to all co-authors 👏
Grateful for my time in Dr. Isabelle Caillé & Pr. Alain Trembleau’s lab #IBPS. Isabelle’s passion for science will keep inspiring me ✨
doi.org/10.1126/scia...
Reposted by Marine Laporte
Save the date!
March 2027 on beautiful lake Maggiore right outside #Milan, are you ready for #Cilia2027? 🥳
Stay tuned for more info!
March 2027 on beautiful lake Maggiore right outside #Milan, are you ready for #Cilia2027? 🥳
Stay tuned for more info!
July 29, 2025 at 8:50 AM
Save the date!
March 2027 on beautiful lake Maggiore right outside #Milan, are you ready for #Cilia2027? 🥳
Stay tuned for more info!
March 2027 on beautiful lake Maggiore right outside #Milan, are you ready for #Cilia2027? 🥳
Stay tuned for more info!
Reposted by Marine Laporte
Attention #microtubule and #centrosome fans!!! Here's another fantastic #openaccess #research #article in #CYTOSKELETON. LZTS2 Negatively Regulates Centrosomal CEP135 Levels and Microtubule Nucleation. Check it out here: onlinelibrary.wiley.com/doi/full/10....
August 1, 2025 at 5:10 PM
Attention #microtubule and #centrosome fans!!! Here's another fantastic #openaccess #research #article in #CYTOSKELETON. LZTS2 Negatively Regulates Centrosomal CEP135 Levels and Microtubule Nucleation. Check it out here: onlinelibrary.wiley.com/doi/full/10....
Reposted by Marine Laporte
🚨 New preprint!
Using U-ExM + in situ cryo-ET, we show how C2CD3 builds an in-to-out radial architecture connecting the distal centriole lumen to its appendages. Great collab with @cellarchlab.com @chgenoud.bsky.social @stearnslab.bsky.social 🙌. #TeamTomo #UExM
www.biorxiv.org/content/10.1...
Using U-ExM + in situ cryo-ET, we show how C2CD3 builds an in-to-out radial architecture connecting the distal centriole lumen to its appendages. Great collab with @cellarchlab.com @chgenoud.bsky.social @stearnslab.bsky.social 🙌. #TeamTomo #UExM
www.biorxiv.org/content/10.1...
June 19, 2025 at 8:58 AM
🚨 New preprint!
Using U-ExM + in situ cryo-ET, we show how C2CD3 builds an in-to-out radial architecture connecting the distal centriole lumen to its appendages. Great collab with @cellarchlab.com @chgenoud.bsky.social @stearnslab.bsky.social 🙌. #TeamTomo #UExM
www.biorxiv.org/content/10.1...
Using U-ExM + in situ cryo-ET, we show how C2CD3 builds an in-to-out radial architecture connecting the distal centriole lumen to its appendages. Great collab with @cellarchlab.com @chgenoud.bsky.social @stearnslab.bsky.social 🙌. #TeamTomo #UExM
www.biorxiv.org/content/10.1...
Reposted by Marine Laporte
It's #WorldOceanDay – this year’s theme is: ‘Wonder: sustain what sustains us’. One key force sustaining ocean life is microbes. With @embl.org TREC we explored this hidden universe along Europe's coasts, across water, sediment and soil to see how microbial life connects across ecosystems and biomes
June 8, 2025 at 10:20 AM
It's #WorldOceanDay – this year’s theme is: ‘Wonder: sustain what sustains us’. One key force sustaining ocean life is microbes. With @embl.org TREC we explored this hidden universe along Europe's coasts, across water, sediment and soil to see how microbial life connects across ecosystems and biomes
Reposted by Marine Laporte
During #mitosis, before assembling the mitotic spindle, the early mouse embryo lacking #centrosomes uses #actin rather than #microtubules for chromosome congression 👀👇🏼
I’m excited to announce that my paper describing non-canonical mitotic mechanisms in the early mouse embryo is out in @science.org ! (link at end of 🧵)
May 24, 2025 at 11:03 AM
During #mitosis, before assembling the mitotic spindle, the early mouse embryo lacking #centrosomes uses #actin rather than #microtubules for chromosome congression 👀👇🏼
Reposted by Marine Laporte
New online: Mesoscale regulation of microtubule-organizing centers by the E3 ligase TRIM37
Mesoscale regulation of microtubule-organizing centers by the E3 ligase TRIM37
Nature Structural & Molecular Biology, Published online: 25 May 2025; doi:10.1038/s41594-025-01540-6Here Yeow et al. present a model in which TRIM37 regulates microtubule-organizing centers through substrate-templated activation, providing a unifying mechanism for the control of mesoscale assemblies by the TRIM family of E3 ligases.
go.nature.com
May 25, 2025 at 10:19 AM
New online: Mesoscale regulation of microtubule-organizing centers by the E3 ligase TRIM37
Reposted by Marine Laporte
Nice cool study, @syncellbiolab, @anubhav_dhar, @SuchetaDey69384, @MullickSan22454, @Nishaant_PB, @deepak_iisc and Angana. Wonderful to be collaborating with you on this work and looking at #actin #isoforms in #yeast and #mammalian_cells using #UExM.
Preprint: IntAct-U-ExM enables robust, isoform-specific expansion microscopy of actin networks in yeast and mammalian cells. A cool study led by @anubhavdhar.bsky.social in collaboration with Sudarshan and Deepak Nair. www.biorxiv.org/content/10.1...
May 17, 2025 at 2:54 PM
Nice cool study, @syncellbiolab, @anubhav_dhar, @SuchetaDey69384, @MullickSan22454, @Nishaant_PB, @deepak_iisc and Angana. Wonderful to be collaborating with you on this work and looking at #actin #isoforms in #yeast and #mammalian_cells using #UExM.
On my way to the #NeuroFrance2025 in Montpellier ! Looking forward to see exciting science and present my recent work to the community
May 14, 2025 at 5:33 AM
On my way to the #NeuroFrance2025 in Montpellier ! Looking forward to see exciting science and present my recent work to the community
Reposted by Marine Laporte
Join me May 20 @ 11 AM ET for a webinar with Bio-protocol!
I'll walk through our single-shot 20-fold expansion microscopy (20ExM) method + share the full protocol so you can try it too.
I'll walk through our single-shot 20-fold expansion microscopy (20ExM) method + share the full protocol so you can try it too.
📢 Bio-protocol Webinars present: Next-generation expansion microscopy: 20× magnification in one step
🔗Register now!
Join us on:
🗓 Date: May 20, 2025
⏰ Time: 11:00 AM EST
Speaker: Shiwei Wang
#Webinar #LifeSciences #Microscopy
🔗Register now!
Join us on:
🗓 Date: May 20, 2025
⏰ Time: 11:00 AM EST
Speaker: Shiwei Wang
#Webinar #LifeSciences #Microscopy
May 1, 2025 at 3:11 PM
Join me May 20 @ 11 AM ET for a webinar with Bio-protocol!
I'll walk through our single-shot 20-fold expansion microscopy (20ExM) method + share the full protocol so you can try it too.
I'll walk through our single-shot 20-fold expansion microscopy (20ExM) method + share the full protocol so you can try it too.
Reposted by Marine Laporte
We dedicated this paper to Michel Bornens who passed away 3 years ago. He would have enjoyed this movie so much!
Unlike eggs & mitotic cells, in adherent interphasic cells the centrosome is NOT positioned by a balance of forces along #microtubules, but by cell shape organization around the #centrosome: rupress.org/jcb/article/...
@lblanchoin.bsky.social
@manuelthery.bsky.social
@gelinmatthieu.bsky.social
@lblanchoin.bsky.social
@manuelthery.bsky.social
@gelinmatthieu.bsky.social
April 17, 2025 at 5:00 PM
We dedicated this paper to Michel Bornens who passed away 3 years ago. He would have enjoyed this movie so much!
Reposted by Marine Laporte
A Morpho-Proteomic Atlas of Mitosis at Sub-Minute Resolution https://www.biorxiv.org/content/10.1101/2025.04.09.647158v1
April 10, 2025 at 11:30 PM
A Morpho-Proteomic Atlas of Mitosis at Sub-Minute Resolution https://www.biorxiv.org/content/10.1101/2025.04.09.647158v1