Ivana Gasic
@ivanagasic.bsky.social
SNSF Assistant Professor @UNIGE
www.gasic.net
www.gasic.net
Lab’s 2nd story aired today!
Fantastic @ac-almeida.bsky.social cracks the cellular function of tubulin autoregulation - an over four decades old enigma!
Read on to learn how she deployed human 3D cell culture models to link tubulin homeostasis to tissue organization & viability. Bravo Ana! 👏🏻🍾
Fantastic @ac-almeida.bsky.social cracks the cellular function of tubulin autoregulation - an over four decades old enigma!
Read on to learn how she deployed human 3D cell culture models to link tubulin homeostasis to tissue organization & viability. Bravo Ana! 👏🏻🍾
🔎New preprint!
We reveal a physiological role for tubulin autoregulation, fine-tuning microtubule dynamics and preserving 3D cellular architecture.
Big thanks to @ivanagasic.bsky.social and team!
Link below for all #cytoskeleton & #spheroid enthusiasts👇(1/5)
www.biorxiv.org/content/10.1...
We reveal a physiological role for tubulin autoregulation, fine-tuning microtubule dynamics and preserving 3D cellular architecture.
Big thanks to @ivanagasic.bsky.social and team!
Link below for all #cytoskeleton & #spheroid enthusiasts👇(1/5)
www.biorxiv.org/content/10.1...
Tubulin autoregulation tunes microtubule dynamics to support multicellular architecture and viability
Alpha- and beta-tubulin heterodimers dynamically assemble into microtubules, key cytoskeletal elements involved in intracellular trafficking, cell adhesion and division. The availability of free tubul...
www.biorxiv.org
July 30, 2025 at 9:32 PM
Lab’s 2nd story aired today!
Fantastic @ac-almeida.bsky.social cracks the cellular function of tubulin autoregulation - an over four decades old enigma!
Read on to learn how she deployed human 3D cell culture models to link tubulin homeostasis to tissue organization & viability. Bravo Ana! 👏🏻🍾
Fantastic @ac-almeida.bsky.social cracks the cellular function of tubulin autoregulation - an over four decades old enigma!
Read on to learn how she deployed human 3D cell culture models to link tubulin homeostasis to tissue organization & viability. Bravo Ana! 👏🏻🍾
Arresting mitosis with visible light! Brilliant Victoria von Glasenapp from the Gotta and Winssinger labs @UNIGE develops a cool photo-caged PLK1 inhibitor, which we deploy in 3D spheroids to control mitosis with exquisite spatio-temporal precision. Check out the original article: lnkd.in/eTnzy5Nc
Spatio-temporal control of mitosis using light via a Plk1 inhibitor caged for activity and cellular permeability - Nature Communications
Light is a powerful tool for controlling biological processes. Here, the authors demonstrate its use to modulate inhibitor activity and diffusion, enabling precise control of cell division in multicel...
lnkd.in
February 24, 2025 at 2:11 PM
Arresting mitosis with visible light! Brilliant Victoria von Glasenapp from the Gotta and Winssinger labs @UNIGE develops a cool photo-caged PLK1 inhibitor, which we deploy in 3D spheroids to control mitosis with exquisite spatio-temporal precision. Check out the original article: lnkd.in/eTnzy5Nc
When you come out of your midterm evaluation and your amazing team surprises you with these beauties 😍💐! Thank you, the ProMiCe team, for these flowers, support, and the brilliant work you are doing 🥰🙏!
November 28, 2024 at 8:13 AM
When you come out of your midterm evaluation and your amazing team surprises you with these beauties 😍💐! Thank you, the ProMiCe team, for these flowers, support, and the brilliant work you are doing 🥰🙏!
Hello Bluesky community! What a better way to introduce myself and my research team than post our lab’s first paper freshly off press 🥳🍾
We reveal how tubulins regulate the stability of their mRNA via reversible sequestration of TTC5. Bravo A. Batiuk and all coauthors 👏🏻🥂
doi.org/10.1038/s414...
We reveal how tubulins regulate the stability of their mRNA via reversible sequestration of TTC5. Bravo A. Batiuk and all coauthors 👏🏻🥂
doi.org/10.1038/s414...
Soluble αβ-tubulins reversibly sequester TTC5 to regulate tubulin mRNA decay - Nature Communications
When tubulin proteins are present in excess, their encoding mRNAs are selectively degraded in a process initiated by the protein TTC5. Here, the authors show that tubulins themselves reversibly seques...
doi.org
November 18, 2024 at 8:03 PM
Hello Bluesky community! What a better way to introduce myself and my research team than post our lab’s first paper freshly off press 🥳🍾
We reveal how tubulins regulate the stability of their mRNA via reversible sequestration of TTC5. Bravo A. Batiuk and all coauthors 👏🏻🥂
doi.org/10.1038/s414...
We reveal how tubulins regulate the stability of their mRNA via reversible sequestration of TTC5. Bravo A. Batiuk and all coauthors 👏🏻🥂
doi.org/10.1038/s414...