Toby Hillman
@tobyhillman.bsky.social
Consultant Respiratory Physician, Long COVID Physician. Interested in almost anything but using this for medical stuff. Other platforms for hobbies.
Reposted by Toby Hillman
Annals of Medicine: Mitochondrial function is impaired in long COVID patients
A study comparing Long COVID patients with controls found altered mitochondrial activity in immune cells, including abnormal ATP synthase behaviour.
Read more: https://meassociation.org.uk/icpw
#LongCovid #MECFS
A study comparing Long COVID patients with controls found altered mitochondrial activity in immune cells, including abnormal ATP synthase behaviour.
Read more: https://meassociation.org.uk/icpw
#LongCovid #MECFS
Annals of Medicine: Mitochondrial function is impaired in long COVID patients - The ME Association
On the 12th August, 2025, the following paper, ‘Mitochondrial function […]
meassociation.org.uk
August 13, 2025 at 10:35 AM
Annals of Medicine: Mitochondrial function is impaired in long COVID patients
A study comparing Long COVID patients with controls found altered mitochondrial activity in immune cells, including abnormal ATP synthase behaviour.
Read more: https://meassociation.org.uk/icpw
#LongCovid #MECFS
A study comparing Long COVID patients with controls found altered mitochondrial activity in immune cells, including abnormal ATP synthase behaviour.
Read more: https://meassociation.org.uk/icpw
#LongCovid #MECFS
Reposted by Toby Hillman
Evidence that Long Covid is fundamentally a disease of mitochondrial dysfunction is becoming overwhelming. Exciting b/c this points toward both potential diagnostics and future therapeutics. I wish my wife could have lived to see this hopeful progress.
www.tandfonline.com/doi/full/10....
www.tandfonline.com/doi/full/10....
Mitochondrial function is impaired in long COVID patients
The Long COVID syndrome is a major global health problem, affecting approximately 10–20% of individuals infected with SARS-CoV-2 virus with many remaining symptomatic beyond one year. Fatigue, redu...
www.tandfonline.com
August 13, 2025 at 3:46 PM
Evidence that Long Covid is fundamentally a disease of mitochondrial dysfunction is becoming overwhelming. Exciting b/c this points toward both potential diagnostics and future therapeutics. I wish my wife could have lived to see this hopeful progress.
www.tandfonline.com/doi/full/10....
www.tandfonline.com/doi/full/10....
Reposted by Toby Hillman
NL Times: 'Growing number of long covid patients declared unfit for work'
'The number of people in the Netherlands declared partially or fully unfit for work due to long Covid has risen sharply in recent years...more than 12,000 people..'
nltimes.nl/2025/03/03/g...
'The number of people in the Netherlands declared partially or fully unfit for work due to long Covid has risen sharply in recent years...more than 12,000 people..'
nltimes.nl/2025/03/03/g...
Growing number of long covid patients declared unfit for work
The number of people in the Netherlands declared partially or fully unfit for work due to long Covid has risen sharply in recent years. According to figures from the Employee Insurance Agency (UWV), m...
nltimes.nl
March 3, 2025 at 3:24 PM
NL Times: 'Growing number of long covid patients declared unfit for work'
'The number of people in the Netherlands declared partially or fully unfit for work due to long Covid has risen sharply in recent years...more than 12,000 people..'
nltimes.nl/2025/03/03/g...
'The number of people in the Netherlands declared partially or fully unfit for work due to long Covid has risen sharply in recent years...more than 12,000 people..'
nltimes.nl/2025/03/03/g...
Reposted by Toby Hillman
Reposted by Toby Hillman
We're looking again at the Chief Medical Officer's 2022 #AirPollution report and noting how much diesel contributes to the nitrogen oxides we are breathing across England. Diesel needs to go. #DitchDiesel https://buff.ly/4hY9erU
February 18, 2025 at 1:00 PM
We're looking again at the Chief Medical Officer's 2022 #AirPollution report and noting how much diesel contributes to the nitrogen oxides we are breathing across England. Diesel needs to go. #DitchDiesel https://buff.ly/4hY9erU
Population-health impact of new drugs recommended by the National Institute for Health and Care Excellence in England during 2000–20: a retrospective analysis - The Lancet www.thelancet.com/journals/lan... > v thought provoking paper on the opportunity costs of ever more advanced (£) treatments
Population-health impact of new drugs recommended by the National Institute for Health and Care Excellence in England during 2000–20: a retrospective analysis
During 2000–20, NHS coverage of new drugs displaced more population health than it
generated. Our results highlight the inherent trade-offs between individuals who directly
benefit from new drugs and ...
www.thelancet.com
January 22, 2025 at 7:37 PM
Population-health impact of new drugs recommended by the National Institute for Health and Care Excellence in England during 2000–20: a retrospective analysis - The Lancet www.thelancet.com/journals/lan... > v thought provoking paper on the opportunity costs of ever more advanced (£) treatments
And please don’t anyone put the cart before the horse interpreting this paper. There is NOTHING about causation - only that those suffering with LC need support for both body and mind. Holistic care doesn’t ignore psychology- bad care often does
December 24, 2024 at 5:19 AM
And please don’t anyone put the cart before the horse interpreting this paper. There is NOTHING about causation - only that those suffering with LC need support for both body and mind. Holistic care doesn’t ignore psychology- bad care often does
Conclusion about hire the health system needs to change to take account of post-infection illness absolutely spot on… the next pandemic is only a matter of time - we must prepare not just to cope with the acute phase- but also the aftermath.
'Long COVID and sleep: an urgent call to action' by Dr. Elizabeth Benge, Harvard
'Long COVID underscores the urgent need for a multidisciplinary approach to post-viral care. Patients deserve a medical system that validates their experiences, invests in research...
kevinmd.com/2024/12/long...
'Long COVID underscores the urgent need for a multidisciplinary approach to post-viral care. Patients deserve a medical system that validates their experiences, invests in research...
kevinmd.com/2024/12/long...
Long COVID and sleep: an urgent call to action
Long COVID disrupts lives with persistent symptoms, including sleep disturbances, requiring urgent research and compassionate care to improve patient outcomes.
kevinmd.com
December 24, 2024 at 5:16 AM
Conclusion about hire the health system needs to change to take account of post-infection illness absolutely spot on… the next pandemic is only a matter of time - we must prepare not just to cope with the acute phase- but also the aftermath.
Reposted by Toby Hillman
'Long COVID and sleep: an urgent call to action' by Dr. Elizabeth Benge, Harvard
'Long COVID underscores the urgent need for a multidisciplinary approach to post-viral care. Patients deserve a medical system that validates their experiences, invests in research...
kevinmd.com/2024/12/long...
'Long COVID underscores the urgent need for a multidisciplinary approach to post-viral care. Patients deserve a medical system that validates their experiences, invests in research...
kevinmd.com/2024/12/long...
Long COVID and sleep: an urgent call to action
Long COVID disrupts lives with persistent symptoms, including sleep disturbances, requiring urgent research and compassionate care to improve patient outcomes.
kevinmd.com
December 23, 2024 at 2:43 PM
'Long COVID and sleep: an urgent call to action' by Dr. Elizabeth Benge, Harvard
'Long COVID underscores the urgent need for a multidisciplinary approach to post-viral care. Patients deserve a medical system that validates their experiences, invests in research...
kevinmd.com/2024/12/long...
'Long COVID underscores the urgent need for a multidisciplinary approach to post-viral care. Patients deserve a medical system that validates their experiences, invests in research...
kevinmd.com/2024/12/long...
Reposted by Toby Hillman
'2024 Science Highlights from the NIH Director’s Blog'
Featured on the Top 6: 'Many People with Long COVID Have Signs of Persistent SARS-CoV-2 Proteins, New Findings Show'
directorsblog.nih.gov/2024/12/20/2...
Featured on the Top 6: 'Many People with Long COVID Have Signs of Persistent SARS-CoV-2 Proteins, New Findings Show'
directorsblog.nih.gov/2024/12/20/2...
2024 Science Highlights from the NIH Director’s Blog
This year on the NIH Director’s Blog, we covered a wide range of NIH-supported research from across our institutes and centers. We explored exciting new findings that came from clinical trials and …
directorsblog.nih.gov
December 20, 2024 at 9:16 PM
'2024 Science Highlights from the NIH Director’s Blog'
Featured on the Top 6: 'Many People with Long COVID Have Signs of Persistent SARS-CoV-2 Proteins, New Findings Show'
directorsblog.nih.gov/2024/12/20/2...
Featured on the Top 6: 'Many People with Long COVID Have Signs of Persistent SARS-CoV-2 Proteins, New Findings Show'
directorsblog.nih.gov/2024/12/20/2...
Reposted by Toby Hillman
Random geography facts as we head towards the end of the year:
Glasgow is north of the southern tip of Alaska
Edinburgh is west of Bristol
Denver, Colorado is south of Rome
France's longest land border is with Brazil
The town of Vardø in Norway is nearer to China than to Portugal
Glasgow is north of the southern tip of Alaska
Edinburgh is west of Bristol
Denver, Colorado is south of Rome
France's longest land border is with Brazil
The town of Vardø in Norway is nearer to China than to Portugal
December 18, 2024 at 8:19 PM
Random geography facts as we head towards the end of the year:
Glasgow is north of the southern tip of Alaska
Edinburgh is west of Bristol
Denver, Colorado is south of Rome
France's longest land border is with Brazil
The town of Vardø in Norway is nearer to China than to Portugal
Glasgow is north of the southern tip of Alaska
Edinburgh is west of Bristol
Denver, Colorado is south of Rome
France's longest land border is with Brazil
The town of Vardø in Norway is nearer to China than to Portugal
Reposted by Toby Hillman
Calcific aortic stenosis is a prevalent, progressive disorder in older adults, diagnosed via echocardiography. This narrative review describes the clinical presentation, diagnostic evaluation, and management of calcific aortic stenosis.
ja.ma/3OWLMyN #CardioSky #MedSky
ja.ma/3OWLMyN #CardioSky #MedSky
December 17, 2024 at 6:02 PM
Calcific aortic stenosis is a prevalent, progressive disorder in older adults, diagnosed via echocardiography. This narrative review describes the clinical presentation, diagnostic evaluation, and management of calcific aortic stenosis.
ja.ma/3OWLMyN #CardioSky #MedSky
ja.ma/3OWLMyN #CardioSky #MedSky
Reposted by Toby Hillman
@therestpolitics.bsky.social hey - any explanation for the inability to play on Amazon music? Has there been a falling out?
December 16, 2024 at 9:36 AM
@therestpolitics.bsky.social hey - any explanation for the inability to play on Amazon music? Has there been a falling out?
I thought I saw a link somewhere on here recently about very much simplified approach to anticoagulation choices in AF. Did I dream it? #help #medsky #cardiosky
December 11, 2024 at 10:13 PM
I thought I saw a link somewhere on here recently about very much simplified approach to anticoagulation choices in AF. Did I dream it? #help #medsky #cardiosky
Reposted by Toby Hillman
A new study from @unibirmingham.bsky.social has shown that burning wood at home produces more PM2.5 #AirPollution than road traffic. Based on Prof Zongbo Shi's findings, which even he was surprised by, people should think twice before installing a wood burning stove.
Air pollution: Wood burners more polluting than traffic - Birmingham research
Birmingham researchers say they have found wood burning at home is more polluting than traffic.
buff.ly
December 11, 2024 at 8:00 PM
A new study from @unibirmingham.bsky.social has shown that burning wood at home produces more PM2.5 #AirPollution than road traffic. Based on Prof Zongbo Shi's findings, which even he was surprised by, people should think twice before installing a wood burning stove.
Reposted by Toby Hillman
Published in JAMA with #CCRdownunder:
In critically ill adults with suspected sepsis, antibiotic regimens were safely reduced when guided by measurement of procalcitonin but not by C-reactive protein. @criticalcarereviews.com
ja.ma/3BovM5v
In critically ill adults with suspected sepsis, antibiotic regimens were safely reduced when guided by measurement of procalcitonin but not by C-reactive protein. @criticalcarereviews.com
ja.ma/3BovM5v
December 9, 2024 at 10:20 PM
Published in JAMA with #CCRdownunder:
In critically ill adults with suspected sepsis, antibiotic regimens were safely reduced when guided by measurement of procalcitonin but not by C-reactive protein. @criticalcarereviews.com
ja.ma/3BovM5v
In critically ill adults with suspected sepsis, antibiotic regimens were safely reduced when guided by measurement of procalcitonin but not by C-reactive protein. @criticalcarereviews.com
ja.ma/3BovM5v
Absolutely thrilled to be at the Royal Institution for the Christmas Lecture tonight - given by Dr Chris... Excitement building in the lecture theatre. Fulfilment of a life long ambition for me!
December 10, 2024 at 5:42 PM
Absolutely thrilled to be at the Royal Institution for the Christmas Lecture tonight - given by Dr Chris... Excitement building in the lecture theatre. Fulfilment of a life long ambition for me!
Reposted by Toby Hillman
New asthma guideline’s treatment algorithm for 12+ 🫁:
🎉 Start with the AIR (anti inflammatory reliever)
✅ No more SABA 🙌
✅ No more theophylline
✅ Unified, simple pathway
#BTSWinter2024
🎉 Start with the AIR (anti inflammatory reliever)
✅ No more SABA 🙌
✅ No more theophylline
✅ Unified, simple pathway
#BTSWinter2024
November 28, 2024 at 9:09 AM
New asthma guideline’s treatment algorithm for 12+ 🫁:
🎉 Start with the AIR (anti inflammatory reliever)
✅ No more SABA 🙌
✅ No more theophylline
✅ Unified, simple pathway
#BTSWinter2024
🎉 Start with the AIR (anti inflammatory reliever)
✅ No more SABA 🙌
✅ No more theophylline
✅ Unified, simple pathway
#BTSWinter2024
Reposted by Toby Hillman
The new NICE/BTS/SIGN #Asthma guidelines are superb. A collaborative approach. A focus on using blood eos and FeNO at initial presentation and finally the long-overdue end to salbutamol. Read it and use it now www.nice.org.uk/guidance/NG245
Overview | Asthma: diagnosis, monitoring and chronic asthma management (BTS, NICE, SIGN) | Guidance | NICE
www.nice.org.uk
November 28, 2024 at 9:31 AM
The new NICE/BTS/SIGN #Asthma guidelines are superb. A collaborative approach. A focus on using blood eos and FeNO at initial presentation and finally the long-overdue end to salbutamol. Read it and use it now www.nice.org.uk/guidance/NG245
Reposted by Toby Hillman
The HPV vaccine has been recommended in the US since 2006. New study out today shows that cervical cancer deaths in young women in the years that followed have plummeted, decreasing 15% per year from 2013-2015.
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Cervical Cancer Mortality Among US Women Younger Than 25 Years
This study examines trends in cervical cancer mortality in US women aged younger than 25 years before and after the introduction of human papillomavirus vaccines.
jamanetwork.com
November 28, 2024 at 2:43 AM
The HPV vaccine has been recommended in the US since 2006. New study out today shows that cervical cancer deaths in young women in the years that followed have plummeted, decreasing 15% per year from 2013-2015.
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Reposted by Toby Hillman
New guidelines.
Asthma: diagnosis, monitoring and chronic asthma management (BTS, NICE, SIGN).
www.nice.org.uk/guidance/ng245 #BTSWinter2024 #LungSky #RespEd
Asthma: diagnosis, monitoring and chronic asthma management (BTS, NICE, SIGN).
www.nice.org.uk/guidance/ng245 #BTSWinter2024 #LungSky #RespEd
Overview | Asthma: diagnosis, monitoring and chronic asthma management (BTS, NICE, SIGN) | Guidance | NICE
www.nice.org.uk
November 27, 2024 at 11:06 AM
New guidelines.
Asthma: diagnosis, monitoring and chronic asthma management (BTS, NICE, SIGN).
www.nice.org.uk/guidance/ng245 #BTSWinter2024 #LungSky #RespEd
Asthma: diagnosis, monitoring and chronic asthma management (BTS, NICE, SIGN).
www.nice.org.uk/guidance/ng245 #BTSWinter2024 #LungSky #RespEd
Reposted by Toby Hillman
Clear clinical statement. Treating tobacco dependence as a disease = person centered approach to managing nicotine withdrawal. Important to prescribe sufficient nicotine substitution products immediately, and give patients access to the most effective evidence based treatments for smoking cessation
BTS Clinical Statement
Medical management of inpatients with tobacco dependency
thorax.bmj.com/content/79/S... #LungSky #RespEd @bmj.com
Medical management of inpatients with tobacco dependency
thorax.bmj.com/content/79/S... #LungSky #RespEd @bmj.com
November 27, 2024 at 2:03 PM
Clear clinical statement. Treating tobacco dependence as a disease = person centered approach to managing nicotine withdrawal. Important to prescribe sufficient nicotine substitution products immediately, and give patients access to the most effective evidence based treatments for smoking cessation