Skywalker
@skywalkersymes.bsky.social
I like physics and computers and complex systems and doing something good in the world. Recovering from LongCovid. I live in Aotearoa/NZ. He/him.
Reposted by Skywalker
Oral Health during and following Covid infection are seriously important
👇🏻👇🏻👇🏻
www.nature.com/articles/s41...
👇🏻👇🏻👇🏻
www.nature.com/articles/s41...
Variations in oral health outcomes and mycobiome composition among COVID-19 convalescents - Scientific Reports
Scientific Reports - Variations in oral health outcomes and mycobiome composition among COVID-19 convalescents
www.nature.com
July 2, 2025 at 9:10 AM
Oral Health during and following Covid infection are seriously important
👇🏻👇🏻👇🏻
www.nature.com/articles/s41...
👇🏻👇🏻👇🏻
www.nature.com/articles/s41...
Reposted by Skywalker
🧬🐄 NEW PREPRINT: Really happy to finally share the last big piece of work from my PhD!
Spoiler: Cows are great and so are their viromes 🧵1/13
www.biorxiv.org/content/10.1...
Spoiler: Cows are great and so are their viromes 🧵1/13
www.biorxiv.org/content/10.1...
Life-Stage Transitions Drive Distinct Gut Viral Communities in Dairy Cattle
Ruminant gut microbial communities profoundly influence host health and environmental impacts, yet their viral components remain poorly characterised across developmental transitions. Here, we analyse...
www.biorxiv.org
May 25, 2025 at 9:05 AM
🧬🐄 NEW PREPRINT: Really happy to finally share the last big piece of work from my PhD!
Spoiler: Cows are great and so are their viromes 🧵1/13
www.biorxiv.org/content/10.1...
Spoiler: Cows are great and so are their viromes 🧵1/13
www.biorxiv.org/content/10.1...
Reposted by Skywalker
Finally, our greatest assets are fresh water, reasonably sound institutions, a creaking but functional green energy infrastructure, our creative and diverse populace, and a resurgent indigenous culture. I'm more worried by soil loss than a few billionaries pissing off to the Caymans tbh. [Ends]
May 18, 2025 at 7:46 AM
Finally, our greatest assets are fresh water, reasonably sound institutions, a creaking but functional green energy infrastructure, our creative and diverse populace, and a resurgent indigenous culture. I'm more worried by soil loss than a few billionaries pissing off to the Caymans tbh. [Ends]
Reposted by Skywalker
Interesting. Increased plasma levels of fibrinogen and haptoglobin observed in persons who have significant/severe #LongCovid, and were even predictive of mortality (28 cases in the sample of 240+)
'Plasma protein biomarkers for long COVID-19: Predictors of symptom severity and mortality risk'
'Plasma protein biomarkers for long COVID-19: Predictors of symptom severity and mortality risk'
Plasma protein biomarkers for long COVID-19: Predictors of symptom severity and mortality risk
Long COVID-19 is marked by persistent symptoms beyond the acute phase, necessitating a deeper understanding of mortality risk factors for effective ma…
www.sciencedirect.com
May 16, 2025 at 7:45 PM
Interesting. Increased plasma levels of fibrinogen and haptoglobin observed in persons who have significant/severe #LongCovid, and were even predictive of mortality (28 cases in the sample of 240+)
'Plasma protein biomarkers for long COVID-19: Predictors of symptom severity and mortality risk'
'Plasma protein biomarkers for long COVID-19: Predictors of symptom severity and mortality risk'
Reposted by Skywalker
Real bombshell of an update from Michael Peluso in this symposium: UCSF's highly-anticipated monoclonal antibody trial did not find the treatment helped alleviate Long COVID symptoms. He speculated that viral persistence may be a less promising avenue for LC than many have long hypothesized.
Today @thesicktimes.bsky.social: We are liveblogging the @polybiorf.bsky.social Spring Symposium! Check this article for updates from the research presentations throughout the day. thesicktimes.org/2025/05/16/l...
Live blog: Following the Spring 2025 PolyBio Symposium on Long COVID and related diseases - The Sick Times
Leading scientists studying Long COVID and related chronic diseases are set to present updates to their work on Friday at the PolyBio Research Foundation’s Spring Symposium. The Sick Times’ team will ...
thesicktimes.org
May 16, 2025 at 5:02 PM
Real bombshell of an update from Michael Peluso in this symposium: UCSF's highly-anticipated monoclonal antibody trial did not find the treatment helped alleviate Long COVID symptoms. He speculated that viral persistence may be a less promising avenue for LC than many have long hypothesized.
Reposted by Skywalker
Quite disheartening to return from 10 days working with some of the most important and relevant #MECFS and #LongCOVID researchers in the world and to read this drivel being allowed through from @bmj_latest. Let's be unambiguous about this: BMJ has
www.bmj.com/content/389/...
1/
www.bmj.com/content/389/...
1/
Patients with severe ME/CFS need hope and expert multidisciplinary care
Reframing beliefs about illness, along with specialist rehabilitation, can help recovery in people with severe ME/CFS, write Alastair Miller, Fiona Symington, Paul Garner, and Maria Pedersen
Myalgic...
www.bmj.com
May 15, 2025 at 8:34 AM
Quite disheartening to return from 10 days working with some of the most important and relevant #MECFS and #LongCOVID researchers in the world and to read this drivel being allowed through from @bmj_latest. Let's be unambiguous about this: BMJ has
www.bmj.com/content/389/...
1/
www.bmj.com/content/389/...
1/
Reposted by Skywalker
Reposted by Skywalker
#MEAwareness
#MillionsMissing
#DisabilitySOS
#WorldMEDay
#GreatestMEdicalScandal
@meactnet.bsky.social
@thesicktimes.bsky.social
@berlin-buyers-club.bsky.social
@notjustfatigue.bsky.social
@johnvsjonvsme.bsky.social
@openmedf.bsky.social
@patientled.bsky.social
@polybiorf.bsky.social
8/
#MillionsMissing
#DisabilitySOS
#WorldMEDay
#GreatestMEdicalScandal
@meactnet.bsky.social
@thesicktimes.bsky.social
@berlin-buyers-club.bsky.social
@notjustfatigue.bsky.social
@johnvsjonvsme.bsky.social
@openmedf.bsky.social
@patientled.bsky.social
@polybiorf.bsky.social
8/
May 11, 2025 at 7:26 PM
Reposted by Skywalker
Powerful moment at Sir Bob Geldof's event: Belinda & Brooke Nickeas (ME/CFS community) shared a letter outlining the history of ME/CFS. Touched by their courage, he shared these words 💙 On #MECFS Awareness Day, their act is a gift. You are seen. You matter.
May 12, 2025 at 5:33 AM
Powerful moment at Sir Bob Geldof's event: Belinda & Brooke Nickeas (ME/CFS community) shared a letter outlining the history of ME/CFS. Touched by their courage, he shared these words 💙 On #MECFS Awareness Day, their act is a gift. You are seen. You matter.
Reposted by Skywalker
CIDRAP: 'Long COVID has unique symptoms, persistence not seen in flu, pneumonia, research suggests'
'The findings were published yesterday in PLOS One'
www.cidrap.umn.edu/covid-19/lon...
'The findings were published yesterday in PLOS One'
www.cidrap.umn.edu/covid-19/lon...
Long COVID has unique symptoms, persistence not seen in flu, pneumonia, research suggests
www.cidrap.umn.edu
April 30, 2025 at 9:06 PM
CIDRAP: 'Long COVID has unique symptoms, persistence not seen in flu, pneumonia, research suggests'
'The findings were published yesterday in PLOS One'
www.cidrap.umn.edu/covid-19/lon...
'The findings were published yesterday in PLOS One'
www.cidrap.umn.edu/covid-19/lon...
Reposted by Skywalker
Newsletter: I am sick and god damn tired of everybody pretending that generative AI is the next big thing. The media is complicit in accepting fantastical nonsense - both in the numbers put out by OpenAI and the silly jobs created by Anthropic - and it has to stop.
www.wheresyoured.at/reality-check/
www.wheresyoured.at/reality-check/
Reality Check
I'm sick and god-damn tired of this! I have written tens of thousands of words about this and still, to this day, people are babbling about the "AI revolution" as the sky rains blood and crevices open...
www.wheresyoured.at
April 28, 2025 at 5:11 PM
Newsletter: I am sick and god damn tired of everybody pretending that generative AI is the next big thing. The media is complicit in accepting fantastical nonsense - both in the numbers put out by OpenAI and the silly jobs created by Anthropic - and it has to stop.
www.wheresyoured.at/reality-check/
www.wheresyoured.at/reality-check/
Reposted by Skywalker
The UK is a fascist state with the pretence of democracy.
Autism is not a disease. Being trans is not a disease. Neither need cured. Leave us the fuck alone!!
Autism is not a disease. Being trans is not a disease. Neither need cured. Leave us the fuck alone!!
April 27, 2025 at 7:15 PM
The UK is a fascist state with the pretence of democracy.
Autism is not a disease. Being trans is not a disease. Neither need cured. Leave us the fuck alone!!
Autism is not a disease. Being trans is not a disease. Neither need cured. Leave us the fuck alone!!
Reposted by Skywalker
May is #Lymedisease awareness month. Spreading the word by sharing our cover image of the new issue of Science Translational Medicine. The issue has two papers that provide a new possible Lyme treatment while enhancing our understanding of Lyme disease symptoms
#sciencenews #HHS #chronic_disease
#sciencenews #HHS #chronic_disease
April 23, 2025 at 6:39 PM
May is #Lymedisease awareness month. Spreading the word by sharing our cover image of the new issue of Science Translational Medicine. The issue has two papers that provide a new possible Lyme treatment while enhancing our understanding of Lyme disease symptoms
#sciencenews #HHS #chronic_disease
#sciencenews #HHS #chronic_disease
Reposted by Skywalker
New paper alert-outstanding postdoc Mecaila McClune has deeply enriched our understanding of #Lymedisease pathogenesis through live, real-time peptidoglycan #glycotime tracking. Her work draws curious parallels to #LongCovid & infection associated chronic illness
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
The peptidoglycan of Borrelia burgdorferi can persist in discrete tissues and cause systemic responses consistent with chronic illness
Polymeric Borrelia burgdorferi peptidoglycan cell wall can persist in murine livers for weeks to months after direct injection or infection.
www.science.org
April 23, 2025 at 6:33 PM
New paper alert-outstanding postdoc Mecaila McClune has deeply enriched our understanding of #Lymedisease pathogenesis through live, real-time peptidoglycan #glycotime tracking. Her work draws curious parallels to #LongCovid & infection associated chronic illness
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Skywalker
In another paper published, Maegan Gabby created a high resolution screen to ID a new possible treatment for #Lymedisease. Mechanistic studies show how an FDA approved drug works at a dose 100x less than doxy to specifically kill the Lyme agent!
www.science.org/doi/10.1126/scitranslmed.adr9091
www.science.org/doi/10.1126/scitranslmed.adr9091
A high-resolution screen identifies a preexisting beta-lactam that specifically treats Lyme disease in mice
Piperacillin, an FDA-approved beta-lactam, is effective at killing the Lyme disease–causing agent Borrelia burgdorferi.
www.science.org
April 23, 2025 at 6:36 PM
In another paper published, Maegan Gabby created a high resolution screen to ID a new possible treatment for #Lymedisease. Mechanistic studies show how an FDA approved drug works at a dose 100x less than doxy to specifically kill the Lyme agent!
www.science.org/doi/10.1126/scitranslmed.adr9091
www.science.org/doi/10.1126/scitranslmed.adr9091
Reposted by Skywalker
“i’ve always been an ignorant piece of shit my entire life guys”
RFK JR: ADD, ADHD, Tourette syndrome, Narcolepsy, Autism.. All of these are injuries that I never heard of when I was a kid.
April 22, 2025 at 11:57 PM
“i’ve always been an ignorant piece of shit my entire life guys”
Reposted by Skywalker
If you ever hear someone say "It feels like my brain is on fire", don't psychologize them. This is what neuroinflammation looks like.
Imagine being a red blood cell whose only mission is to deliver oxygen, only to find a river of fire waiting for you inside the brain. #NeuroCovid
Imagine being a red blood cell whose only mission is to deliver oxygen, only to find a river of fire waiting for you inside the brain. #NeuroCovid
April 10, 2025 at 3:11 AM
If you ever hear someone say "It feels like my brain is on fire", don't psychologize them. This is what neuroinflammation looks like.
Imagine being a red blood cell whose only mission is to deliver oxygen, only to find a river of fire waiting for you inside the brain. #NeuroCovid
Imagine being a red blood cell whose only mission is to deliver oxygen, only to find a river of fire waiting for you inside the brain. #NeuroCovid
Reposted by Skywalker
If you think it’ll stop at Columbia and Harvard, you’re wrong. If you think it won’t go beyond universities to infiltrate all schools, you’re wrong. If you think it won’t demand compliance at media, medical, and non-profit organizations, you’re wrong. Fascism is here. Fight it.
April 1, 2025 at 1:42 AM
If you think it’ll stop at Columbia and Harvard, you’re wrong. If you think it won’t go beyond universities to infiltrate all schools, you’re wrong. If you think it won’t demand compliance at media, medical, and non-profit organizations, you’re wrong. Fascism is here. Fight it.
Reposted by Skywalker
Students horrified by this who attend a protest may find themselves on their university's radar (or much, much worse). Speakers whose slides mention the deaths of humanitarian workers have their invitations rescinded. We can know about these atrocities, but we cannot speak of them. How obscene.
March 31, 2025 at 3:39 PM
Students horrified by this who attend a protest may find themselves on their university's radar (or much, much worse). Speakers whose slides mention the deaths of humanitarian workers have their invitations rescinded. We can know about these atrocities, but we cannot speak of them. How obscene.
Too much Vitamin A can overload your ALDH enzymes which in chronic illness may already be under pressure. Potentially leading to Vitamin A toxicity and liver damage. Most Vit A supplements dosages are too high, safest to get it from a healthy diet.
As the Texas measles outbreak continues, doctors there are treating some children given so much vitamin A that they have signs of liver damage. Story by @teddyrosenbluth.bsky.social Gift link: www.nytimes.com/2025/03/25/h...
For Some Measles Patients, Vitamin A Remedy Supported by RFK Jr. Leaves Them More Ill (Gift Article)
After the health secretary promoted vitamin A as a cure, parents in West Texas began giving their children high doses, sometimes to prevent infection.
www.nytimes.com
March 26, 2025 at 12:00 AM
Too much Vitamin A can overload your ALDH enzymes which in chronic illness may already be under pressure. Potentially leading to Vitamin A toxicity and liver damage. Most Vit A supplements dosages are too high, safest to get it from a healthy diet.
Reposted by Skywalker
can’t sleep, thinking about that ridiculous basilisk and what kind of warped mind it takes to believe you have the power to build god but not the power to make god not-evil
like
my dude
simply build a nicer god wtf is wrong with you
like
my dude
simply build a nicer god wtf is wrong with you
March 23, 2025 at 7:04 AM
can’t sleep, thinking about that ridiculous basilisk and what kind of warped mind it takes to believe you have the power to build god but not the power to make god not-evil
like
my dude
simply build a nicer god wtf is wrong with you
like
my dude
simply build a nicer god wtf is wrong with you
Reposted by Skywalker
This one is important, especially under Trump. The directions may be very slightly changed with later android / iOS updates but you 100% can still remove the advertising ID.
LE buys this data then link you to a time & place and then track you anywhere via advertising ID
www.eff.org/deeplinks/20...
LE buys this data then link you to a time & place and then track you anywhere via advertising ID
www.eff.org/deeplinks/20...
How to Disable Ad ID Tracking on iOS and Android, and Why You Should Do It Now
The ad identifier - aka “IDFA” on iOS, or “AAID” on Android - is the key that enables most third-party tracking on mobile devices. Disabling it will make it substantially harder for advertisers and da...
www.eff.org
March 24, 2025 at 3:06 AM
This one is important, especially under Trump. The directions may be very slightly changed with later android / iOS updates but you 100% can still remove the advertising ID.
LE buys this data then link you to a time & place and then track you anywhere via advertising ID
www.eff.org/deeplinks/20...
LE buys this data then link you to a time & place and then track you anywhere via advertising ID
www.eff.org/deeplinks/20...
Reposted by Skywalker
This is hugely important. Thx Dr. Ruth Ann Crystal.
"These findings suggest that Vitamin B12 may help mitigate neuroinflammation in Long COVID by modulating gene expression through methylation, offering a potential therapeutic approach for cognitive impairment."
www.nature.com/articles/s41...
"These findings suggest that Vitamin B12 may help mitigate neuroinflammation in Long COVID by modulating gene expression through methylation, offering a potential therapeutic approach for cognitive impairment."
www.nature.com/articles/s41...
Vitamin B12 as an epidrug for regulating peripheral blood biomarkers in long COVID-associated visuoconstructive deficit - Scientific Reports
Scientific Reports - Vitamin B12 as an epidrug for regulating peripheral blood biomarkers in long COVID-associated visuoconstructive deficit
www.nature.com
March 23, 2025 at 7:43 PM
This is hugely important. Thx Dr. Ruth Ann Crystal.
"These findings suggest that Vitamin B12 may help mitigate neuroinflammation in Long COVID by modulating gene expression through methylation, offering a potential therapeutic approach for cognitive impairment."
www.nature.com/articles/s41...
"These findings suggest that Vitamin B12 may help mitigate neuroinflammation in Long COVID by modulating gene expression through methylation, offering a potential therapeutic approach for cognitive impairment."
www.nature.com/articles/s41...
Reposted by Skywalker
All along we've thought that aged white blood cells (neutrophils) promote inflammation and were detrimental. Now there's a discovery of aged neutrophils with Large AgingNeutrophil-Derived Vesicles (LAND-Vs)that are anti-inflammatory and help clear bacteria
www.cell.com/cell/abstrac...
www.cell.com/cell/abstrac...
March 20, 2025 at 5:07 PM
All along we've thought that aged white blood cells (neutrophils) promote inflammation and were detrimental. Now there's a discovery of aged neutrophils with Large AgingNeutrophil-Derived Vesicles (LAND-Vs)that are anti-inflammatory and help clear bacteria
www.cell.com/cell/abstrac...
www.cell.com/cell/abstrac...
Reposted by Skywalker
Two research programs coming out of New Zealand: developing an early detection test for myalgic encephalomyelitis and long Covid, and a test to determine familial susceptibility to those diseases. Game changers if successfull
#ME/CFS
#LongCovid
#MillionsMissing
alumni.otago.ac.nz/donate/myalg...
#ME/CFS
#LongCovid
#MillionsMissing
alumni.otago.ac.nz/donate/myalg...
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome/Long Covid - University of Otago
Donate towards Professor Warren Tate's research on Myalgic Encephalomyelitis/Chronic Fatigue syndrome (ME/CFS). Support research into Chronic Fatigue Syndrome/Long Covid
alumni.otago.ac.nz
March 18, 2025 at 1:47 AM
Two research programs coming out of New Zealand: developing an early detection test for myalgic encephalomyelitis and long Covid, and a test to determine familial susceptibility to those diseases. Game changers if successfull
#ME/CFS
#LongCovid
#MillionsMissing
alumni.otago.ac.nz/donate/myalg...
#ME/CFS
#LongCovid
#MillionsMissing
alumni.otago.ac.nz/donate/myalg...