Silvia Remeseiro Lab
remeseiro-lab.bsky.social
Silvia Remeseiro Lab
@remeseiro-lab.bsky.social
Associate Professor & Docent @umeauniversitet.bsky.social
Wallenberg Fellow in Molecular Medicine at WCMM Umeå
Postdoc @embl.org
PhD @cniostopcancer.bsky.social
3D genomics , epigenomics, gene regulation, enhancer, cancer, glioblastoma, cancer neuroscience
Reposted by Silvia Remeseiro Lab
Excited to share I’ve received a #SSMF #Consolidator grant!

📣 Recruiting a #postdoc to study #cancer #neuroscience #3Dgenomics #multiomics #singlecellomics

🔬How neural inputs shape #3Dgenome and #cellplasticity in #glioblastoma #GBM

Interested? Apply now 👇
rb.gy/m7xz7b
Postdoctoral Researcher in "Cancer Neuroscience: the impact of neural activity on 3D genome organization and cellular plasticity in glioblastoma”
rb.gy
November 14, 2025 at 11:00 AM
Reposted by Silvia Remeseiro Lab
🚨Reposts appreciated‼️If I had read this PhD offer five years ago, I wouldn’t have hesitated for a second to apply 😉
Passionate about gene regulation, chromatin, and developmental biology? Just contact @radaiglesiaslab.bsky.social at @ibbtec.bsky.social 🧬✨

#PhD #3DGenome
November 15, 2025 at 9:53 AM
Excited to share I’ve received a #SSMF #Consolidator grant!

📣 Recruiting a #postdoc to study #cancer #neuroscience #3Dgenomics #multiomics #singlecellomics

🔬How neural inputs shape #3Dgenome and #cellplasticity in #glioblastoma #GBM

Interested? Apply now 👇
rb.gy/m7xz7b
Postdoctoral Researcher in "Cancer Neuroscience: the impact of neural activity on 3D genome organization and cellular plasticity in glioblastoma”
rb.gy
November 14, 2025 at 11:00 AM
#CancerNeuroscience EACR conference there we go!
📣 Today is the day!! 📣

The @helloeacr.bsky.social #CancerNeuroscience conference will kick off in beautiful Bilbao, Spain.
🇪🇸 🧠🤩

It’s an excellent program 😍
We are looking forward to many interesting new insights and discussions! 💡

See you in a few hours! 👋

#cancer #neuroscience #EACRconference
Introduction | Cancer Neuroscience | The European Association for Cancer Research
eacr.org
October 14, 2025 at 12:46 PM
Reposted by Silvia Remeseiro Lab
Thanks to all speakers, including bsky users @winklerlab.bsky.social @claudiakleinman.bsky.social @nelander-lab.bsky.social @gocastelobranco.bsky.social, the Ragnar Söderberg foundation, and co-hosts @remeseiro-lab.bsky.social, @maawim.bsky.social, and Fredrik Swartling.
September 19, 2025 at 5:50 AM
Reposted by Silvia Remeseiro Lab
Emmanuelle Charpentier has been appointed honorary citizen of Umeå Municipality, and in connection with the honorary citizenship ceremony, the Nobel Prize winner is making a long-awaited visit to her alma mater for a public seminar/talk. Read more here: www.umu.se/en/events/se...
September 3, 2025 at 7:00 AM
Reposted by Silvia Remeseiro Lab
#Preprint alert! 📣

We are thrilled to share the work led by Lara Zorro-Shahidian and Lucio di Filippo, in which we show that #MLL2 controls gene expression in both #ESC and upon #differentiation by facilitating the #enhancer like activity of #LINE1 elements

www.biorxiv.org/cgi/content/...
MLL2 facilitates long-range gene regulation through LINE1 elements
Transcriptional regulation is tightly linked to chromatin organization, with H3K4me3 commonly marking both active and bivalent promoters. In embryonic stem cells (ESC), MLL2 is essential for H3K4me3 d...
www.biorxiv.org
August 13, 2025 at 5:54 AM
Now out @genomeresearch.bsky.social this fantastic work in collaboration with Claudio Cantù's lab.

About how #Wnt signalling activation induces #CTCF binding and formation of new #chromatin #loops at #CREs of target genes.

genome.cshlp.org/content/earl...
August 1, 2025 at 1:58 PM
Reposted by Silvia Remeseiro Lab
The latest upgrading of the #supercomputer Berzelius @liu.se has now been completed. Its doubled capacity enables researchers across Sweden to tackle current and future challenges in areas such as materials science, bioinformatics and machine learning #research #science
tinyurl.com/ydduwzc7
Stronger Berzelius ready for the research of the future
The latest upgrading of the supercomputer Berzelius at LiU has now been completed. Its doubled capacity enables researchers across Sweden to tackle current and future challenges in areas such as mater...
tinyurl.com
June 4, 2025 at 12:03 PM
Reposted by Silvia Remeseiro Lab
Nu är den senaste uppgraderingen av superdatorn Berzelius @liu.se klar. Med en fördubblad kapacitet kan forskare i hela Sverige ta sig an samtidens och framtidens utmaningar inom bland annat materialvetenskap, bioinformatik och maskininlärning #forskning #vetenskap
tinyurl.com/nns7pks6
Starkare Berzelius är redo för framtidens forskning
Nu är den senaste uppgraderingen av superdatorn Berzelius vid LiU klar. Med en fördubblad kapacitet kan forskare i hela Sverige ta sig an samtidens och framtidens utmaningar inom bland annat materialv...
tinyurl.com
June 4, 2025 at 12:01 PM
Reposted by Silvia Remeseiro Lab
Really looking forward to @radaiglesiaslab.bsky.social's talk on "Gaining mechanistic insights into long-range gene regulation through synthetic biology approaches" in @enhancedgenomics.bsky.social's seminar series.

📅 June 5th 2025 tomorrow
⏰ 4pm GMT

Please join us:
us02web.zoom.us/webinar/regi...
Welcome! You are invited to join a webinar: The 3D Regulatory Genome: Gaining mechanistic insights into long-range gene regulation through synthetic biology approaches. After registering, you will rec...
Join our guest speaker, Dr. Alvaro Rada-Iglesias, in this exciting seminar on the 3D Regulatory Genome, sponsored by Enhanced Genomics.
us02web.zoom.us
June 4, 2025 at 12:37 PM
Are you a US-based researcher who want to return to #Sweden 🇸🇪 to establish your #research here?

This is your shot to make it happen 👇
strategiska.se/en/press-rel...
45 million in research support for returnees from USA!
strategiska.se
May 29, 2025 at 9:18 AM
Reposted by Silvia Remeseiro Lab
How to find Evolutionary Conserved Enhancers in 2025? 🐣-🐭
Check out our paper - fresh off the press!!!
We find widespread functional conservation of enhancers in absence of sequence homology
Including: a bioinformatic tool to map sequence-diverged enhancers!
rdcu.be/enVDN
github.com/tobiaszehnde...
Conservation of regulatory elements with highly diverged sequences across large evolutionary distances
Nature Genetics - Combining functional genomic data from mouse and chicken with a synteny-based strategy identifies positionally conserved cis-regulatory elements in the absence of direct sequence...
rdcu.be
May 27, 2025 at 12:19 PM
📣 New pre-print from the lab:
👉 “Gene regulatory networks linked to GABA signalling emerge as relevant for glioblastoma pathogenesis” #Glioblastoma #GB #GRNs #multiomics #GABA #CancerNeuroscience #ML #GBM

📝 Read the #BioRxiv here:
doi.org/10.1101/2025...
May 21, 2025 at 8:55 AM
Reposted by Silvia Remeseiro Lab
🚨 We’re hiring a bioinformatics-focused PhD student for our ERC-funded project on recurrent GBM! Focus: tumor-supportive microenvironment 🔬 Experience with scRNA-seq, spatial transcriptomics & Python/R a plus. Must be self-motivated & driven. DM for details! Repost=❤️ lu.varbi.com/en/what:job/...
Doctoral Student in Tumor Biology
Description of the workplace The research group conducts experimental research on brain tumors and is led by Associate Professor Alexander Pietras. The group consists of a bioinformatician, two postdo
lu.varbi.com
May 15, 2025 at 8:27 AM
Spetses Summer School on Functional Genomics of Metabolic Diseases

functionalgenomics2025.febsevents.org
FEBS Advanced Lecture Course 2025 – Functional genomics of metabolic diseases<br />
August 29 – September 3, 2025 │ Spetses Island, Greece
functionalgenomics2025.febsevents.org
May 15, 2025 at 7:10 AM
Link to register here 👇
www.kva.se/evenemang/br...
May 13, 2025 at 6:54 AM
Reposted by Silvia Remeseiro Lab
Just a few spots left for this exciting symposium on brain tumor plasticity—grab yours (free of charge!) before they're gone! 🚨
May 12, 2025 at 2:37 PM
🎫 Exclusive event: One-day symposium on #Brain #Tumor #Plasticity
🕣September 16, 2025. The Royal Swedish Academy of Sciences, Stockholm @scienceacademyswe.bsky.social

Few spots available. Register here: ui.ungpd.com/Events/ed387...
Brain Tumor Plasticity
A growing body of evidence emphasizes the presence of significant intra-tumoral phenotypic diversity and plasticity within brain tumors. Inherent plasticity introduces an additional layer of intricacy...
ui.ungpd.com
May 12, 2025 at 12:42 PM
Reposted by Silvia Remeseiro Lab
I’m very excited to share our work on the early evolution of animal regulatory genome architecture - the main project of my postdoc, carried out across two wonderful and inspirational labs of @arnausebe.bsky.social and @mamartirenom.bsky.social. www.nature.com/articles/s41...
Chromatin loops are an ancestral hallmark of the animal regulatory genome - Nature
The physical organization of the genome in non-bilaterian animals and their closest&nbsp;unicellular relatives is characterized; comparative analysis shows chromatin looping is a conserved feature of ...
www.nature.com
May 7, 2025 at 3:23 PM
Reposted by Silvia Remeseiro Lab
Epichrom 2025 !

After 3 years, Epichrom is revived and will take place in Stockholm on the 12th of June. Great opportunity to share your research and hear about latest epigenetics/chromatin research in Sweden.

Registration is free of charge
www.bartosovic-lab.com/epichrom
LinkedIn
This link will take you to a page that’s not on LinkedIn
lnkd.in
May 7, 2025 at 5:23 AM
Reposted by Silvia Remeseiro Lab
A tour de force study from Taipale&Yin labs. It expands the vocabulary of the Regulatory Code by adding 1131 TF:TF composite motifs that are different from the individual TF motifs. The new composite motifs are enriched in cell-type specific elements and active in vivo
www.nature.com/articles/s41...
DNA-guided transcription factor interactions extend human gene regulatory code - Nature
A large-scale analysis of DNA-bound transcription factors (TFs) shows how the presence of DNA markedly affects the landscape of TF interactions, and identifies composite motifs that are recognized by ...
www.nature.com
April 9, 2025 at 4:51 PM
Now online the last work published in collaboration with @hornblad-lab.bsky.social

insight.jci.org/articles/vie...
JCI Insight - AMPK activator ATX-304 reduces oxidative stress and improves MASLD via metabolic switching
insight.jci.org
April 10, 2025 at 8:14 PM