María Mariner
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mariamafau.bsky.social
María Mariner
@mariamafau.bsky.social
Postdoctoral researcher at @radaiglesiaslab.bsky.social | Developmental genomics | Prelighter (The Company of Biologists) | Artistic & Creative | Passionate about visual storytelling and design
Pinned
Thrilled to share the story stemming from my PhD!
We used mESC neural differentiation, genome editing and bulk & single-cell approaches to uncover how ZIC2 controls early neural fate by playing a dual and sequential regulatory role as a promiscous pioneer and a selective lineage-specific activator.
Reposted by María Mariner
Applications for our international #PhD program open until 11th Jan. Come work with us @uoe-igc.bsky.social and @hannahlong.bsky.social to understand DNMT3B in ICF syndrome or with our wonderful colleagues.
Details here:
institute-genetics-cancer.ed.ac.uk/igc-graduate...
#epigenetics Please repost 🙏
December 19, 2025 at 10:31 AM
Mi top 1 de #ESDLB 2025. Qué (casi) 3h de disfrute! Bioética y "Ser Científico" pasando por xenotransplantes, OMGs y (mi parte fav) Labradores simpáticos 🦮 y Síndrome de Williams! @lluismontoliu.bsky.social en youtu.be/uZGrvNpMCGM?...
La Modificación Genética en Personas, Animales y Plantas | Lluis Montoliu #ESDLB Cap.605
YouTube video by El Sentido De La Birra con Ricardo Moya
youtu.be
December 14, 2025 at 1:40 PM
Reposted by María Mariner
Probably the ugliest animal I've been requested to illustrate so far... and so beautiful at the same time :) So much fun to draw!
#bats #sciart #art
December 12, 2025 at 9:44 AM
Reposted by María Mariner
🧬🎉Join us on Dec 17th for our last session of 2025! 🎉🧬Two fantastic talks on transcriptional regulation:
🔬JB Lalanne on developmental enhancers (and starting a lab in 2025?)
🔬 @rberrens.bsky.social on transposable elements in development
📋Register here: us06web.zoom.us/webinar/regi...
December 11, 2025 at 6:54 PM
Reposted by María Mariner
A stem-cell-based monkey embryo model that self-organizes into a comprehensive body plan could lead the way to more-sophisticated models of early human development

go.nature.com/48yxsG6
Primate embryo model leaps across developmental boundaries
A stem-cell-based monkey embryo model that self-organizes into a comprehensive body plan could lead the way to more-sophisticated models of early human development.
go.nature.com
December 4, 2025 at 8:37 AM
Reposted by María Mariner
Want to analyze the role of endogenous retroviruses in early human development or investigate their regulation in pluripotency and early development for your PhD?

Join the lab of @fueyoraquel.bsky.social via the IMPRS-BAC #gradschool!

👉 www.molgen.mpg.de/5094682/Fuey...
November 27, 2025 at 2:06 PM
Reposted by María Mariner
🔔Join us next Wednesday for #FragileNucleosome! 2 fantastic talks on chromatin regulation:🔬 @mariamafau.bsky.social on ZIC2's dual role in neural induction 🔬 @jhenninger.bsky.social on how RNA-binding proteins drive transcription
📋Register here for the entire series: us06web.zoom.us/webinar/regi...
November 26, 2025 at 10:16 AM
Reposted by María Mariner
Do you have an exciting new chromatin/transcription story that you'd like to share with the #FN community?

Fill out this form to be considered for a talk in our Jan-June 2026 schedule! forms.gle/TBi38UgYxPAB...

Please repost and share!
Application to speak in the Fragile Nucleosome series
Thank you for your interest in our seminar series! We use a variety of different session formats but, in general, trainees can plan for a ~15 min talk + 5min Q/A and PIs can plan for a ~25min talk +...
forms.gle
November 24, 2025 at 1:50 PM
Reposted by María Mariner
Major new direction in the lab: hacking human cell biology with pathogen effectors (eORFs) - amazing collaboration with @miketilapia.bsky.social lab. Huge congrats to first authors Tomas & He & all co-authors! Check out the pre-print on @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...
www.biorxiv.org
November 18, 2025 at 2:51 PM
Reposted by María Mariner
IMPRS-BAC #gradschool: Our new groupleader @sedonamurphy.bsky.social has an open PhD project in her lab. Topic: Spatial feedback between epigenetic regulation and chromatin regulation. Apply by Jan 7, 2026!
👉 www.molgen.mpg.de/5091778/Murp...
November 18, 2025 at 4:05 PM
Reposted by María Mariner
🔔This Wednesday , in #FragileNucleosome seminar, we are excited to host @ishtiaqueh.bsky.social of Pastor lab and Prof. Sarah Teichmann, @teichlab.bsky.social, to tell us about their exciting studies!
🗓️Register here for upcoming session and the entire series:
us06web.zoom.us/webinar/regi...
November 18, 2025 at 9:43 AM
🚨Reposts appreciated‼️If I had read this PhD offer five years ago, I wouldn’t have hesitated for a second to apply 😉
Passionate about gene regulation, chromatin, and developmental biology? Just contact @radaiglesiaslab.bsky.social at @ibbtec.bsky.social 🧬✨

#PhD #3DGenome
November 15, 2025 at 9:53 AM
Reposted by María Mariner
OFERTA DE EMPLEO (por favor difundir):

Ofrecemos un contrato predoctoral de 4 años asociado a nuestro proyecto PID2024-157249OB-I00. El objetivo del proyecto es evaluar un nuevo mecanismo patológico según el cual la competición entre promotores puede llegar a ocasionar enfermedades congénitas
👇
November 6, 2025 at 5:24 PM
Reposted by María Mariner
2nd Meeting on Early Embryogenesis and Epigenetics
16 - 18 Feb 2026 at MPI for Molecular Genetics, Berlin
with support by the Weizmann Institute for Science.
Early bird registration until 30 Sep - register now👇
www.molgen.mpg.de/embryo2026
September 26, 2025 at 1:09 PM
Reposted by María Mariner
🚨🚨🚨 Please repost
We are looking for postdocs to join our lab at NIH.
Apply:
www.nichd.nih.gov/research/atNICHD/Investigators/rocha/apply
Learn more about training at NIH :
www.training.nih.gov/research-tra...
September 8, 2025 at 3:15 PM
Reposted by María Mariner
Axolotl (Ambystoma mexicanum)🦎 can regrow limbs, tail, spinal cord, heart, and even parts of its brain. Axolotls are champions of regeneration and also shed light on limb patterning, wound healing, and developmental plasticity. Image from Prayag Murawala #ModelMonday #DevBio
September 2, 2025 at 12:11 AM
Honoured to be part of this awesome lineup 😍! @fnucleosome.bsky.social thanks for the opportunity! A very exciting Fall Season is about to start, I wouldn't miss it 😌🧬
We're super excited to announce the entire lineup for the Fall season of Fragile Nucleosome Seminars, starting on Sept 10th at 1200 EDT / 1600 UTC with @gracebower.bsky.social and @creminslab.bsky.social!

register here for the entire series: us06web.zoom.us/webinar/regi...
September 2, 2025 at 8:56 AM
Reposted by María Mariner
We are searching for a research technician in our group at EMBL Heidelberg! 🧫🧬🔬

For more details, see the ad. Please reach out in case of any questions.

The position is ideally filled by October 1.

embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Research Technician
We are looking for a highly motivated research technician to join the Zaugg group at EMBL Heidelberg, an interdisciplinary team of experimental and computational scientists. Our research combines larg...
embl.wd103.myworkdayjobs.com
September 1, 2025 at 7:37 AM
Reposted by María Mariner
#Preprint alert! 📣

We are thrilled to share the work led by Lara Zorro-Shahidian and Lucio di Filippo, in which we show that #MLL2 controls gene expression in both #ESC and upon #differentiation by facilitating the #enhancer like activity of #LINE1 elements

www.biorxiv.org/cgi/content/...
MLL2 facilitates long-range gene regulation through LINE1 elements
Transcriptional regulation is tightly linked to chromatin organization, with H3K4me3 commonly marking both active and bivalent promoters. In embryonic stem cells (ESC), MLL2 is essential for H3K4me3 d...
www.biorxiv.org
August 13, 2025 at 5:54 AM
🗒️‼️Do not miss this exciting new #preprint from the @radaiglesiaslab.bsky.social, led by @eharo84.bsky.social: a master of building synergy ⏫- both in #enhancer research and at the lab! #DarkGenome #Transcription #GeneRegulation #Development #Genomics
August 11, 2025 at 4:16 PM
Reposted by María Mariner
#JobOffer
#cienciajobs

Postdoctoral position at the #CABD working with the amazing and dynamic team of @crisprscan.bsky.social ✂️🧬🐟

📍Sevilla, Spain

Apply or share

@sebioldev.bsky.social @segenetica.bsky.social @sebbm.bsky.social
July 24, 2025 at 8:24 PM
Thrilled to share the story stemming from my PhD!
We used mESC neural differentiation, genome editing and bulk & single-cell approaches to uncover how ZIC2 controls early neural fate by playing a dual and sequential regulatory role as a promiscous pioneer and a selective lineage-specific activator.
July 24, 2025 at 4:28 PM
Reposted by María Mariner
⚠️ I am really excited to share the work of Anastasios Balaskas, an excellent PhD candidate in the lab, with the wider world. Tasos made a significant advance: generating a stem cell-based embryo model that contains both posterior and anterior neural tissues of the late-stage gastrulating embryo.
June 23, 2025 at 7:51 AM
Just visited the pond where my passion for developmental biology began🥹. No tadpoles in sight, but I did spot these handsome little guys. Counted over 30 frogs 🐸—most of them covered in moist soil, undergoing estivation!🥵🌄
June 24, 2025 at 6:15 PM
CAR-T therapy dev is on fire! Still remember covering the ARI project (Clínic Bcn-IDIBAPS) as an assignment during my Biotech days at UPV—I am sure Ariana would be smiling, excited to see how fast the field is moving to make the treatment she dreamt of simpler and more accessible.🧡
May 31, 2025 at 3:51 PM