Craig Kaplan
@triggerloop.bsky.social
Professor, Department of Biological Sciences, University of Pittsburgh. RNA polymerase II mechanism, classic films, #classiccountdown once in awhile
Reposted by Craig Kaplan
It is absolutely outrageous that Moderna’s flu vaccine was met with a “refusal-to-file” even after their approved their protocol with FDA and carried out the trial as agreed. This vaccine works better in older adults than the current flu vaccines.
apnews.com/article/mode...
apnews.com/article/mode...
Moderna says FDA refuses its application for new mRNA flu vaccine
The U.S. Food and Drug Administration is refusing to consider Moderna’s application for a new flu vaccine made with mRNA technology.
apnews.com
February 11, 2026 at 12:13 AM
It is absolutely outrageous that Moderna’s flu vaccine was met with a “refusal-to-file” even after their approved their protocol with FDA and carried out the trial as agreed. This vaccine works better in older adults than the current flu vaccines.
apnews.com/article/mode...
apnews.com/article/mode...
@superkash.bsky.social 2026 miles run: 7!!!! I’m on a tear, buddy
February 11, 2026 at 1:47 AM
@superkash.bsky.social 2026 miles run: 7!!!! I’m on a tear, buddy
Reposted by Craig Kaplan
The purpose is to disincentivize investments in vaccine development
NEW: The F.D.A. refused to accept an application from Moderna for its mRNA flu vaccine.
Its reason: The agency did not think Moderna compared the new vaccine to one of the best flu shots available. The company spent $750M+ on a 41,000 person study.
www.nytimes.com/2026/02/10/h...
Its reason: The agency did not think Moderna compared the new vaccine to one of the best flu shots available. The company spent $750M+ on a 41,000 person study.
www.nytimes.com/2026/02/10/h...
F.D.A. Refuses to Review Moderna Flu Vaccine
www.nytimes.com
February 10, 2026 at 11:34 PM
The purpose is to disincentivize investments in vaccine development
Reposted by Craig Kaplan
one chatbot told a participant in this study to go lay down in the dark when he was presenting with a brain hemorrhage... what are we even doing
www.404media.co/chatbots-hea...
www.404media.co/chatbots-hea...
Chatbots Make Terrible Doctors, New Study Finds
Chatbots provided incorrect, conflicting medical advice, researchers found: “Despite all the hype, AI just isn't ready to take on the role of the physician.”
www.404media.co
February 9, 2026 at 4:06 PM
one chatbot told a participant in this study to go lay down in the dark when he was presenting with a brain hemorrhage... what are we even doing
www.404media.co/chatbots-hea...
www.404media.co/chatbots-hea...
Reposted by Craig Kaplan
🧪🧬New preprint We present cryo-EM structures of reconstituted CTCF–nucleosome complexes, showing CTCF dimerization drives nucleosome oligomerization into defined higher-order assemblies. Disrupting CTCF–CTCF interfaces in mESCs reduces looping and impairs differentiation. tinyurl.com/CTCF-nucleos...
February 9, 2026 at 12:54 PM
🧪🧬New preprint We present cryo-EM structures of reconstituted CTCF–nucleosome complexes, showing CTCF dimerization drives nucleosome oligomerization into defined higher-order assemblies. Disrupting CTCF–CTCF interfaces in mESCs reduces looping and impairs differentiation. tinyurl.com/CTCF-nucleos...
Reposted by Craig Kaplan
Just a few weeks ago, the administration cancelled all remaining department of energy grid resilience projects in Puerto Rico. All of them. www.latitudemedia.com/news/the-end...
The end of DOE’s grid work in Puerto Rico
The Trump administration has canceled all eight of the remaining awards devoted to distributed energy on the island.
www.latitudemedia.com
February 9, 2026 at 2:00 AM
Just a few weeks ago, the administration cancelled all remaining department of energy grid resilience projects in Puerto Rico. All of them. www.latitudemedia.com/news/the-end...
Reposted by Craig Kaplan
no eres mis casa bonita
no eres mis esposa bonita
no eres mis esposa bonita
February 9, 2026 at 1:33 AM
no eres mis casa bonita
no eres mis esposa bonita
no eres mis esposa bonita
Reposted by Craig Kaplan
A Reddit user identifies the boy who took a Grammy from Bad Bunny in the halftime show as five-year-old model Lincoln Fox and says that he was meant to represent Bad Bunny as a child www.instagram.com/the_lincfox/... www.reddit.com/user/BabySea...
February 9, 2026 at 2:46 AM
A Reddit user identifies the boy who took a Grammy from Bad Bunny in the halftime show as five-year-old model Lincoln Fox and says that he was meant to represent Bad Bunny as a child www.instagram.com/the_lincfox/... www.reddit.com/user/BabySea...
Reposted by Craig Kaplan
Reposted by Craig Kaplan
“Mr. Beast Salesforce ad” - they’re calling it the least appealing phrase ever assembled in any language. They finally did it
February 9, 2026 at 2:32 AM
“Mr. Beast Salesforce ad” - they’re calling it the least appealing phrase ever assembled in any language. They finally did it
Reposted by Craig Kaplan
NANCY GOAT
February 9, 2026 at 1:50 AM
NANCY GOAT
Reposted by Craig Kaplan
Dump Truck, by Mikhail Evdokimovich Tkachev, 1956
February 9, 2026 at 1:28 AM
Dump Truck, by Mikhail Evdokimovich Tkachev, 1956
Reposted by Craig Kaplan
the coinbase commercial was a karaoke rugpull
February 9, 2026 at 1:02 AM
the coinbase commercial was a karaoke rugpull
Reposted by Craig Kaplan
Mercury, Messenger of the Gods, by Giovanni Battista Tiepolo, 18th c, 📸 by @PhilEllsworth1
February 9, 2026 at 12:57 AM
Mercury, Messenger of the Gods, by Giovanni Battista Tiepolo, 18th c, 📸 by @PhilEllsworth1
Reposted by Craig Kaplan
Eadweard Muybridge: Animal Locomotion: An Electro-Photographic Investigation of Consecutive Phases of Animal Movement 1872-1885
July 19, 2025 at 8:34 AM
Eadweard Muybridge: Animal Locomotion: An Electro-Photographic Investigation of Consecutive Phases of Animal Movement 1872-1885
Such a JAM
February 7, 2026 at 2:54 PM
Such a JAM
Reposted by Craig Kaplan
I am excited to share a new review @cp-molcell.bsky.social written in collaboration with @tanjamittag.bsky.social , Mikayla Eppert, and Ambuja Navalkar where we review the current evidence for and against the role of density transitions in regulating transcription www.cell.com/molecular-ce...
February 6, 2026 at 9:20 PM
I am excited to share a new review @cp-molcell.bsky.social written in collaboration with @tanjamittag.bsky.social , Mikayla Eppert, and Ambuja Navalkar where we review the current evidence for and against the role of density transitions in regulating transcription www.cell.com/molecular-ce...
Reposted by Craig Kaplan
Want to interpret DNA sequence-to-function models to understand the underlying molecular mechanisms? Then this is a must read!
The new updates for Charles McAnany’s preprint “Positional Interpretation of Cis-Regulatory Code and Nucleosome Organization with Deep Learning Models” (www.biorxiv.org/content/10.1...) are up!
We introduce PISA, a tool to visualize the cis-regulatory code. See a recap below:
We introduce PISA, a tool to visualize the cis-regulatory code. See a recap below:
www.biorxiv.org
February 6, 2026 at 4:25 PM
Want to interpret DNA sequence-to-function models to understand the underlying molecular mechanisms? Then this is a must read!
Reposted by Craig Kaplan
New, from me: Trump finalized his Schedule F policy, allowing him to remove job protections from career civil servants.
The new rule is dishonest and unmoored from reality in its effort to formalize the politicization of the federal government 🧵
donmoynihan.substack.com/p/trumps-sch...
The new rule is dishonest and unmoored from reality in its effort to formalize the politicization of the federal government 🧵
donmoynihan.substack.com/p/trumps-sch...
Trump's Schedule F Rule Finalized
A bizarro rule formally justifies politicizing public services
donmoynihan.substack.com
February 6, 2026 at 4:16 AM
New, from me: Trump finalized his Schedule F policy, allowing him to remove job protections from career civil servants.
The new rule is dishonest and unmoored from reality in its effort to formalize the politicization of the federal government 🧵
donmoynihan.substack.com/p/trumps-sch...
The new rule is dishonest and unmoored from reality in its effort to formalize the politicization of the federal government 🧵
donmoynihan.substack.com/p/trumps-sch...
Reposted by Craig Kaplan
Breaking, from me: An executive order from Oklahoma's governor directs most of the state's public colleges to "phase out tenure." #AcademicSky #HigherEd @chronicle.com
www.chronicle.com/article/tenu...
www.chronicle.com/article/tenu...
Tenure Will Be Eliminated at Most of Oklahoma’s Public Colleges, Governor Says
Gov. Kevin Stitt, a Republican, directed the state’s two-dozen regional universities and community colleges to phase out the practice. Existing faculty members will be grandfathered in.
www.chronicle.com
February 5, 2026 at 9:59 PM
Breaking, from me: An executive order from Oklahoma's governor directs most of the state's public colleges to "phase out tenure." #AcademicSky #HigherEd @chronicle.com
www.chronicle.com/article/tenu...
www.chronicle.com/article/tenu...
@cindynorth1.bsky.social exits to freeways
February 6, 2026 at 1:11 AM
@cindynorth1.bsky.social exits to freeways
Reposted by Craig Kaplan
AI Chatbot That Only Responds ‘Huh’ Valued At $200 Billion https://theonion.com/ai-chatbot-that-only-responds-huh-valued-at-200-billion/
February 5, 2026 at 4:00 PM
AI Chatbot That Only Responds ‘Huh’ Valued At $200 Billion https://theonion.com/ai-chatbot-that-only-responds-huh-valued-at-200-billion/
@aavihail.bsky.social I wanted to mention that my Advanced Mol Gen class has started with host-phage module each year and we read your Cell paper as a class!
February 5, 2026 at 4:01 PM
@aavihail.bsky.social I wanted to mention that my Advanced Mol Gen class has started with host-phage module each year and we read your Cell paper as a class!