Rui Fu
@ray-bio.bsky.social
Senior bioinformatics scientist at @nygenome.org. Mostly single-cell now, but still think of myself as an RNA biologist first. Aquarium volunteering and cat pics did wonders for my mental health. https://github.com/raysinensis
Reposted by Rui Fu
Delighted to present our second paper of the year. This one explores the molecular mechanism of TTP, a key post-transcriptional regulator of AU-rich mRNAs. Work led and coordinated by @filippekovic.bsky.social, in collaboration with Perry Blackshear.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Multivalent interactions with CCR4–NOT and PABPC1 determine mRNA repression efficiency by tristetraprolin - Nature Communications
Deadenylation leads to mRNA decay, with PABPC1 protecting the poly(A) tail, while tristetraprolin and CCR4–NOT promote deadenylation. Here, the authors describe how these three proteins interact to re...
www.nature.com
August 13, 2025 at 5:32 PM
Delighted to present our second paper of the year. This one explores the molecular mechanism of TTP, a key post-transcriptional regulator of AU-rich mRNAs. Work led and coordinated by @filippekovic.bsky.social, in collaboration with Perry Blackshear.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Rui Fu
amidst bad stuff these days, check this awesome initiative Shefali @iamshef.bsky.social started last year, and expanding in 2025. #FlyCROSS is a mentor-mentee matching program to help early career Fly scientists at all levels. not only students and PDs, but young faculty. pls participate and share!🪰
Hey #Drosophila folks ! #FlyCROSS is back and #Mentor surveys are open NOW ! If you're a faculty/postdoc/ equivalent in any scientific career & have #Drosophila research experience - we'd be delighted to have you as mentors to empower early career scientists in the #Dros community !
Summer 2025 Survey For Mentors : FlyCROSS Mentor Mentee Matching Program
We appreciate you taking the time and volunteering to be a mentor! Add dmelcross@gmail.com to your email address book or safe sender list, so that you can receive our emails. To be a participating me...
docs.google.com
June 3, 2025 at 8:55 PM
amidst bad stuff these days, check this awesome initiative Shefali @iamshef.bsky.social started last year, and expanding in 2025. #FlyCROSS is a mentor-mentee matching program to help early career Fly scientists at all levels. not only students and PDs, but young faculty. pls participate and share!🪰
Reposted by Rui Fu
Very excited to announce the first **RNA x Tech Dev Mini-Symposium** in collab with the Tri-I RNA Club!
Talks from Chris Mason, Ildar Gainetdinov,
@xuebingwu.bsky.social, and Sanja Vickovic!
Come down to @nygenome.org and hear about the latest in RNA technology development being done in NYC!
Talks from Chris Mason, Ildar Gainetdinov,
@xuebingwu.bsky.social, and Sanja Vickovic!
Come down to @nygenome.org and hear about the latest in RNA technology development being done in NYC!
May 6, 2025 at 1:31 PM
Very excited to announce the first **RNA x Tech Dev Mini-Symposium** in collab with the Tri-I RNA Club!
Talks from Chris Mason, Ildar Gainetdinov,
@xuebingwu.bsky.social, and Sanja Vickovic!
Come down to @nygenome.org and hear about the latest in RNA technology development being done in NYC!
Talks from Chris Mason, Ildar Gainetdinov,
@xuebingwu.bsky.social, and Sanja Vickovic!
Come down to @nygenome.org and hear about the latest in RNA technology development being done in NYC!
Reposted by Rui Fu
I know that the mRNA is larger than the protein it codes for but I don't believe it
March 3, 2025 at 6:07 PM
I know that the mRNA is larger than the protein it codes for but I don't believe it
Reposted by Rui Fu
One of my favorite poems since childhood, and a poem I share every #autumnequinox.
By the 12thc warrior poet Xin Qiji 辛棄疾, sidelined during peacetime, demoted, drifting through a decade of minor posts in remote lands.
Poetry, then, is that which is left unsaid.
“My, what a cool and lovely autumn.”
By the 12thc warrior poet Xin Qiji 辛棄疾, sidelined during peacetime, demoted, drifting through a decade of minor posts in remote lands.
Poetry, then, is that which is left unsaid.
“My, what a cool and lovely autumn.”
September 22, 2024 at 11:07 AM
One of my favorite poems since childhood, and a poem I share every #autumnequinox.
By the 12thc warrior poet Xin Qiji 辛棄疾, sidelined during peacetime, demoted, drifting through a decade of minor posts in remote lands.
Poetry, then, is that which is left unsaid.
“My, what a cool and lovely autumn.”
By the 12thc warrior poet Xin Qiji 辛棄疾, sidelined during peacetime, demoted, drifting through a decade of minor posts in remote lands.
Poetry, then, is that which is left unsaid.
“My, what a cool and lovely autumn.”
Reposted by Rui Fu
HT to Sean Davis for creating a status page for NIH websites: stats.uptimerobot.com/Zrqh8AhvKn - simultaneous worth sharing and sad.
Government Biomedical data
stats.uptimerobot.com
March 2, 2025 at 1:11 PM
HT to Sean Davis for creating a status page for NIH websites: stats.uptimerobot.com/Zrqh8AhvKn - simultaneous worth sharing and sad.
Reposted by Rui Fu
Reposted by Rui Fu
NIH's new policy (NOT-OD-25-068) capping indirect cost reimbursement at 15% threatens the future of research, training, & scientific infrastructure at research institutions nationwide. The NYGC has drafted a petition urging reversal.
Please sign & share within your networks: bit.ly/40KK21a
Please sign & share within your networks: bit.ly/40KK21a
Sign the Petition
Petition to Reverse the NIH Indirect Cost Cap (NOT-OD-25-068)
chng.it
February 10, 2025 at 8:12 PM
NIH's new policy (NOT-OD-25-068) capping indirect cost reimbursement at 15% threatens the future of research, training, & scientific infrastructure at research institutions nationwide. The NYGC has drafted a petition urging reversal.
Please sign & share within your networks: bit.ly/40KK21a
Please sign & share within your networks: bit.ly/40KK21a
Reposted by Rui Fu
Petition to Reverse the NIH Indirect Cost Cap.
Sign and Circulate.
Mobilize. Organize.
chng.it/LS57Nk7r6k
Sign and Circulate.
Mobilize. Organize.
chng.it/LS57Nk7r6k
This campaign needs you now
Petition to Reverse the NIH Indirect Cost Cap (NOT-OD-25-068)
chng.it
February 10, 2025 at 3:38 PM
Petition to Reverse the NIH Indirect Cost Cap.
Sign and Circulate.
Mobilize. Organize.
chng.it/LS57Nk7r6k
Sign and Circulate.
Mobilize. Organize.
chng.it/LS57Nk7r6k
Reposted by Rui Fu
An anonymous person at the CDC just archived all the public CDC datasets as of 1/28 and uploaded it to archive.org
Internet Archive: Digital Library of Free & Borrowable Texts, Movies, Music & Wayback Machine
archive.org
February 2, 2025 at 5:47 PM
An anonymous person at the CDC just archived all the public CDC datasets as of 1/28 and uploaded it to archive.org
Reposted by Rui Fu
Venus and the Moon are gorgeous tonight 😍
February 2, 2025 at 12:41 AM
Venus and the Moon are gorgeous tonight 😍
Reposted by Rui Fu
you either die young or live long enough for The Phantom Menace to become blistering topical commentary
guy who has only seen Star Wars Episode I The Phantom Menace: hmmm I'm getting real Star Wars Episode I The Phantom Menace vibes right now
February 2, 2025 at 2:31 AM
you either die young or live long enough for The Phantom Menace to become blistering topical commentary
Reposted by Rui Fu
On the migration of the scientific community to Bluesky:
www.nature.com/articles/d41... 🧪
www.nature.com/articles/d41... 🧪
Bluesky’s science takeover: 70% of Nature poll respondents use platform
Roughly 6,000 readers answered our poll, with many declaring that Bluesky was nicer, kinder and less antagonistic to science than X.
www.nature.com
January 27, 2025 at 8:19 PM
On the migration of the scientific community to Bluesky:
www.nature.com/articles/d41... 🧪
www.nature.com/articles/d41... 🧪
Reposted by Rui Fu
Made a life size 3D print on Anomolacaris! One of the Earth's first Apex Predators! The segment colors make it look like candy corn. Going to fill and paint it, but in reality we don't know what color it was!
January 13, 2025 at 4:06 AM
Made a life size 3D print on Anomolacaris! One of the Earth's first Apex Predators! The segment colors make it look like candy corn. Going to fill and paint it, but in reality we don't know what color it was!
Reposted by Rui Fu
Sorry, but I really hope people who love THE WILD ROBOT movie know it was inspired by my book. It's mentioned in the credits but most people don't read that stuff. If you love the movie you should check out the book! There's more to the story and it's a quick read.
December 11, 2024 at 3:55 PM
Sorry, but I really hope people who love THE WILD ROBOT movie know it was inspired by my book. It's mentioned in the credits but most people don't read that stuff. If you love the movie you should check out the book! There's more to the story and it's a quick read.
Reposted by Rui Fu
Our new paper shows the utility of Element AVITI sequencing for sequencing through poly(dT)-primed single-cell RNA-seq libraries. This ability enables direct measurement of polyadenylation sites. Fun work with former student John Chamberlin and Austin Gillen.
academic.oup.com/nargab/artic...
academic.oup.com/nargab/artic...
Improved characterization of 3′ single-cell RNA-seq libraries with paired-end avidity sequencing
Abstract. Prevailing poly(dT)-primed 3′ single-cell RNA-seq protocols generate barcoded cDNA fragments containing the reverse transcriptase priming site or
academic.oup.com
December 19, 2024 at 4:49 PM
Our new paper shows the utility of Element AVITI sequencing for sequencing through poly(dT)-primed single-cell RNA-seq libraries. This ability enables direct measurement of polyadenylation sites. Fun work with former student John Chamberlin and Austin Gillen.
academic.oup.com/nargab/artic...
academic.oup.com/nargab/artic...
Reposted by Rui Fu
The mini games anthology that I helped organize for the Ann Arbor District Library for the city's bicentennial is out. Featuring a puzzle game by @flyovergames.bsky.social, game boy game by @itsmelilyv.bsky.social, and point-and-click adventure by me
aadl.org/drchasegames
aadl.org/drchasegames
December 30, 2024 at 3:52 PM
The mini games anthology that I helped organize for the Ann Arbor District Library for the city's bicentennial is out. Featuring a puzzle game by @flyovergames.bsky.social, game boy game by @itsmelilyv.bsky.social, and point-and-click adventure by me
aadl.org/drchasegames
aadl.org/drchasegames
Reposted by Rui Fu
Fish shell 4.0 is out, and it's re-written in Rust! fishshell.com/blog/rustport/
Fish 4.0: The Fish Of Theseus
A smart and user-friendly command line shell
fishshell.com
December 29, 2024 at 2:37 AM
Fish shell 4.0 is out, and it's re-written in Rust! fishshell.com/blog/rustport/
Reposted by Rui Fu
🗓️Here’s a recap of my 2024 year in review and my thoughts about the future
disabilityvisibilityproject.com/2024/12/27/y...
disabilityvisibilityproject.com/2024/12/27/y...
December 30, 2024 at 4:57 AM
🗓️Here’s a recap of my 2024 year in review and my thoughts about the future
disabilityvisibilityproject.com/2024/12/27/y...
disabilityvisibilityproject.com/2024/12/27/y...
Reposted by Rui Fu
Of all the polar bears I saw this fall, this one is probably my favourite. Kelp Bear living its best life. 🐻❄️🦊🌿
December 28, 2024 at 4:28 PM
Of all the polar bears I saw this fall, this one is probably my favourite. Kelp Bear living its best life. 🐻❄️🦊🌿
Reposted by Rui Fu
Btw, speaking of Mitch, he wrote one of my favorite posts on how to motivate yourself to build things: get yourself to a demo.
mitchellh.com/writing/buil...
mitchellh.com/writing/buil...
My Approach to Building Large Technical Projects
mitchellh.com
November 2, 2024 at 12:42 PM
Btw, speaking of Mitch, he wrote one of my favorite posts on how to motivate yourself to build things: get yourself to a demo.
mitchellh.com/writing/buil...
mitchellh.com/writing/buil...
Reposted by Rui Fu
The Swiss typeface designer Adrian Frutiger — creator of Univers, Frutiger, and Avenir — designed this book as a Christmas gift for personal and professional friends in 1969. It contains the creation myth from Genesis in four languages, accompanied by his own modernist illustrations. 1/n
December 25, 2023 at 10:56 PM
The Swiss typeface designer Adrian Frutiger — creator of Univers, Frutiger, and Avenir — designed this book as a Christmas gift for personal and professional friends in 1969. It contains the creation myth from Genesis in four languages, accompanied by his own modernist illustrations. 1/n
Reposted by Rui Fu
Reposted by Rui Fu
My favorite holiday record is “A Charlie Brown Christmas” by Vince Guaraldi. But I’d never seen a photo of him until tonight. I don’t think I was prepared for this!
December 22, 2024 at 11:26 PM
My favorite holiday record is “A Charlie Brown Christmas” by Vince Guaraldi. But I’d never seen a photo of him until tonight. I don’t think I was prepared for this!
Reposted by Rui Fu
The underrated Vib Ribbon soundtrack is great background noise for pre-holiday work www.youtube.com/watch?v=OWzk...
Vib-Ribbon - Soundtrack (Full) (Lyrics)
YouTube video by Ta2
www.youtube.com
December 18, 2024 at 5:27 PM
The underrated Vib Ribbon soundtrack is great background noise for pre-holiday work www.youtube.com/watch?v=OWzk...