Shefali
@iamshef.bsky.social
PhD candidate | AHA Predoc Fellow | Grad student rep at Flyboard | Studying metabolism and development in the Tennessen Lab at IU Bloomington | She is into dancing and Drosophila 💃🏽🎶🎙️👩🏽🔬🔬
Pinned
Shefali
@iamshef.bsky.social
· Jul 21
docs.google.com
#FlyCROSS mentee surveys are open for #earlycareer #Drosophila scientists. If you're a #gradstudent #postdoc or pretenure faculty or equivalent - fill up the survey by Sept 1 to participate & be matched by #mentor of your preferences to gain guidance to your unique needs. @flybase.bsky.social
Reposted by Shefali
Check out our newest issue where we interview @juliesemmelhack.bsky.social, who studies the neural circuits of visual behavior at the Hong Kong University of Science and Technology. www.cell.com/current-biol...
Q & A
Interview with Julie Semmelhack, who studies the neural circuits of visual behavior
at the Hong Kong University of Science and Technology.
www.cell.com
November 10, 2025 at 3:31 PM
Check out our newest issue where we interview @juliesemmelhack.bsky.social, who studies the neural circuits of visual behavior at the Hong Kong University of Science and Technology. www.cell.com/current-biol...
Reposted by Shefali
new Lai lab paper @natsmb.nature.com! Dicer is specifically mutated in cancer, but we don't fully understand its molecular/reg impacts. with @danweihuangfu.bsky.social, we characterized the first knockin Dicer hotspot in hESCs, and found unexpected defects in miRNA biogenesis! 🧬 1/4
rdcu.be/eOc0q
rdcu.be/eOc0q
Human DICER1 hotspot mutation induces both loss and gain of miRNA function
Nature Structural & Molecular Biology - Jee et al. study a cancer hotspot allele of DICER1 that disrupts RNaseIIIb activity. Beyond ablating 5p hairpin cleavage, 3p passenger strands are...
rdcu.be
November 10, 2025 at 4:43 PM
new Lai lab paper @natsmb.nature.com! Dicer is specifically mutated in cancer, but we don't fully understand its molecular/reg impacts. with @danweihuangfu.bsky.social, we characterized the first knockin Dicer hotspot in hESCs, and found unexpected defects in miRNA biogenesis! 🧬 1/4
rdcu.be/eOc0q
rdcu.be/eOc0q
November 9, 2025 at 9:56 PM
This 👇🏽👇🏽👇🏽👇🏽
When people celebrate the individual genius of folks in science, they should also
mourn the collective loss of genius of folks who were actively discouraged or disadvantaged from a career in science because of the same person(s)
mourn the collective loss of genius of folks who were actively discouraged or disadvantaged from a career in science because of the same person(s)
November 8, 2025 at 12:57 AM
This 👇🏽👇🏽👇🏽👇🏽
I don't think my phone camera can do justice to how beautiful #iubloomington campus is during the #fall season 🍁🍂
#fallcolors #midwest
#fallcolors #midwest
November 7, 2025 at 4:43 PM
I don't think my phone camera can do justice to how beautiful #iubloomington campus is during the #fall season 🍁🍂
#fallcolors #midwest
#fallcolors #midwest
Reposted by Shefali
hello 🪰 folks! i'm excited to host tim mosca @drosophilosophy.bsky.social for today's DB Program seminar. if you're on the upper east side of NYC at 2 pm, you don't want to miss his talk!
November 6, 2025 at 12:27 PM
hello 🪰 folks! i'm excited to host tim mosca @drosophilosophy.bsky.social for today's DB Program seminar. if you're on the upper east side of NYC at 2 pm, you don't want to miss his talk!
Reposted by Shefali
My lab at Indiana University is searching for a *postdoc* and *technician* to contribute to our work studying the evolution of social behavior using fruit flies as a model system. Details below, feel free to email me with any questions! More info on our research: saltzlab.com
November 5, 2025 at 4:56 PM
My lab at Indiana University is searching for a *postdoc* and *technician* to contribute to our work studying the evolution of social behavior using fruit flies as a model system. Details below, feel free to email me with any questions! More info on our research: saltzlab.com
My brain - literally right after watching the latest episode of the Great British Baking Show.
🤷🏽♀️🧠🥧
#theGreatBritishBakingShow
🤷🏽♀️🧠🥧
#theGreatBritishBakingShow
a couple of people standing next to each other with the words " i want sweets "
ALT: a couple of people standing next to each other with the words " i want sweets "
media.tenor.com
November 6, 2025 at 2:36 AM
My brain - literally right after watching the latest episode of the Great British Baking Show.
🤷🏽♀️🧠🥧
#theGreatBritishBakingShow
🤷🏽♀️🧠🥧
#theGreatBritishBakingShow
November 5, 2025 at 2:22 PM
When you're contemplating if you should sleep early or pull an all nighter to watch the cricket world cup final at 4am #IndvsSA #womenscricket 🇮🇳🇿🇦
🏏🏆
🏏🏆
November 2, 2025 at 2:41 AM
When you're contemplating if you should sleep early or pull an all nighter to watch the cricket world cup final at 4am #IndvsSA #womenscricket 🇮🇳🇿🇦
🏏🏆
🏏🏆
Reposted by Shefali
Zara Weinberg passed away earlier this week. She joined my lab earlier this year when her postdoc lab formally closed.
She was a brilliant scientist, supportive mentor, dear friend, avid music fan, rabid believer in public transit, open science champion, and above all just an amazing human.
She was a brilliant scientist, supportive mentor, dear friend, avid music fan, rabid believer in public transit, open science champion, and above all just an amazing human.
October 31, 2025 at 1:18 PM
Zara Weinberg passed away earlier this week. She joined my lab earlier this year when her postdoc lab formally closed.
She was a brilliant scientist, supportive mentor, dear friend, avid music fan, rabid believer in public transit, open science champion, and above all just an amazing human.
She was a brilliant scientist, supportive mentor, dear friend, avid music fan, rabid believer in public transit, open science champion, and above all just an amazing human.
Reposted by Shefali
PhD studentshipship available through @swbiodtp.bsky.social! This project will take advantage of an incredible RNAseq dataset we are generating using 40 species and multiple infection types to learn how immune systems evolve.
For more info, see: bit.ly/43zNa20
#Drosophila #Immunity
For more info, see: bit.ly/43zNa20
#Drosophila #Immunity
October 29, 2025 at 4:08 PM
PhD studentshipship available through @swbiodtp.bsky.social! This project will take advantage of an incredible RNAseq dataset we are generating using 40 species and multiple infection types to learn how immune systems evolve.
For more info, see: bit.ly/43zNa20
#Drosophila #Immunity
For more info, see: bit.ly/43zNa20
#Drosophila #Immunity
Reposted by Shefali
These folks are opening our eyes to the diversity of life at the nanometer scale--INCREDIBLE! 🧪
🚨Our collaboration with @centriolelab.bsky.social & @gautamdey.bsky.social is out today in @cp-cell.bsky.social
We show that #Expansion #Microscopy is a broad-spectrum modality for Euks, enabling 3D phenotypic maps rooted to phylogeny.
#ProtistsOnSky #SciComm #SciSky
www.cell.com/cell/fulltex...
We show that #Expansion #Microscopy is a broad-spectrum modality for Euks, enabling 3D phenotypic maps rooted to phylogeny.
#ProtistsOnSky #SciComm #SciSky
www.cell.com/cell/fulltex...
November 1, 2025 at 12:06 PM
These folks are opening our eyes to the diversity of life at the nanometer scale--INCREDIBLE! 🧪
Reposted by Shefali
📣 We are moving to Barcelona to join the amazing @crg.eu and explore how centrosomes & cilia work, evolve & respond to the environment. We are looking for
PhD students www.crg.eu/en/content/t...
Postdocs gimm.pt/jobs/postdoc...
Other calls to open, also for an experienced lab manager.
Get in touch!
PhD students www.crg.eu/en/content/t...
Postdocs gimm.pt/jobs/postdoc...
Other calls to open, also for an experienced lab manager.
Get in touch!
October 30, 2025 at 1:15 PM
📣 We are moving to Barcelona to join the amazing @crg.eu and explore how centrosomes & cilia work, evolve & respond to the environment. We are looking for
PhD students www.crg.eu/en/content/t...
Postdocs gimm.pt/jobs/postdoc...
Other calls to open, also for an experienced lab manager.
Get in touch!
PhD students www.crg.eu/en/content/t...
Postdocs gimm.pt/jobs/postdoc...
Other calls to open, also for an experienced lab manager.
Get in touch!
Reposted by Shefali
Excited to be traveling to meetings.embo.org/event/25-cyt... in Pune, India. Looking forward to seeing friends not seen in years and revisiting for the first time since 2020. My lab is recruiting. Those interested, let’s meet up there! (Look out for ads up here soon.)
Frontiers in Cytoskeleton Research
A key question in biology is how living cells adapt to highly complex functional requirements in the context of an organism, within which they need to develop complex morphologies, interact with many…
meetings.embo.org
November 1, 2025 at 12:26 AM
Excited to be traveling to meetings.embo.org/event/25-cyt... in Pune, India. Looking forward to seeing friends not seen in years and revisiting for the first time since 2020. My lab is recruiting. Those interested, let’s meet up there! (Look out for ads up here soon.)
Reposted by Shefali
🌿 Join us Nov 18, 2pm EST to honor the life and legacy of 2025 Thomas Hunt Morgan Medal recipient Joanne Chory, whose remarkable career and lasting contributions to plant genetics have and continue to inspire generations of scientists.
Register now: buff.ly/cC52bJH
1/2🧵⬇️
Register now: buff.ly/cC52bJH
1/2🧵⬇️
October 31, 2025 at 6:15 PM
🌿 Join us Nov 18, 2pm EST to honor the life and legacy of 2025 Thomas Hunt Morgan Medal recipient Joanne Chory, whose remarkable career and lasting contributions to plant genetics have and continue to inspire generations of scientists.
Register now: buff.ly/cC52bJH
1/2🧵⬇️
Register now: buff.ly/cC52bJH
1/2🧵⬇️
Reposted by Shefali
Happy Halloween from the Niemi lab, dressed as the scariest lab technique, western blots. 😂
October 31, 2025 at 8:58 PM
Happy Halloween from the Niemi lab, dressed as the scariest lab technique, western blots. 😂
Reposted by Shefali
Can't believe it — my first‑author paper is out and my image graces the cover of @dev-journal.bsky.social 🎉
Here, we reveal how early developmental programs shape and maintain #zebrafish gill architecture throughout life
🔗 journals.biologists.com/dev/issue/15...
#FluorescenceFriday #LifelongDevSI
Here, we reveal how early developmental programs shape and maintain #zebrafish gill architecture throughout life
🔗 journals.biologists.com/dev/issue/15...
#FluorescenceFriday #LifelongDevSI
October 31, 2025 at 10:55 AM
Can't believe it — my first‑author paper is out and my image graces the cover of @dev-journal.bsky.social 🎉
Here, we reveal how early developmental programs shape and maintain #zebrafish gill architecture throughout life
🔗 journals.biologists.com/dev/issue/15...
#FluorescenceFriday #LifelongDevSI
Here, we reveal how early developmental programs shape and maintain #zebrafish gill architecture throughout life
🔗 journals.biologists.com/dev/issue/15...
#FluorescenceFriday #LifelongDevSI
Reposted by Shefali
I’ll be co-chairing a session on Neural Circuits and Behavior at #Dros26! 🪰
Fly neuro friends, please submit abstracts! Our session will be 🔥
Deadline Nov 13
Fly neuro friends, please submit abstracts! Our session will be 🔥
Deadline Nov 13
Abstract submission for #Dros26 is now open! 🪰
Browse abstract submission topics online and start preparing your abstract today.
Learn more: buff.ly/N0ajcpu
Browse abstract submission topics online and start preparing your abstract today.
Learn more: buff.ly/N0ajcpu
October 26, 2025 at 2:11 PM
I’ll be co-chairing a session on Neural Circuits and Behavior at #Dros26! 🪰
Fly neuro friends, please submit abstracts! Our session will be 🔥
Deadline Nov 13
Fly neuro friends, please submit abstracts! Our session will be 🔥
Deadline Nov 13
Reposted by Shefali
#DBfeature 🪰
Drosophila grh relies on multiple enhancers for robust expression in neural stem cells, with different combinations playing a critical role in regulating its expression in subsets of these cells
By R Sipani, Y Rawal, J Barman, P Abbur, V Kurlawala, & R Joshi
tinyurl.com/2aufrc2w
Drosophila grh relies on multiple enhancers for robust expression in neural stem cells, with different combinations playing a critical role in regulating its expression in subsets of these cells
By R Sipani, Y Rawal, J Barman, P Abbur, V Kurlawala, & R Joshi
tinyurl.com/2aufrc2w
October 31, 2025 at 2:51 PM
#DBfeature 🪰
Drosophila grh relies on multiple enhancers for robust expression in neural stem cells, with different combinations playing a critical role in regulating its expression in subsets of these cells
By R Sipani, Y Rawal, J Barman, P Abbur, V Kurlawala, & R Joshi
tinyurl.com/2aufrc2w
Drosophila grh relies on multiple enhancers for robust expression in neural stem cells, with different combinations playing a critical role in regulating its expression in subsets of these cells
By R Sipani, Y Rawal, J Barman, P Abbur, V Kurlawala, & R Joshi
tinyurl.com/2aufrc2w
Reposted by Shefali
More extraordinary model systems for regeneration
In their #LifelongDevSI Perspective, José Garcıa-Arraras, Chunyi Li, Tania Rozario, Mansi Srivastava & @andrewilloughb.bsky.social introduce five research organisms with remarkable regenerative potential
doi.org/10.1242/dev....
In their #LifelongDevSI Perspective, José Garcıa-Arraras, Chunyi Li, Tania Rozario, Mansi Srivastava & @andrewilloughb.bsky.social introduce five research organisms with remarkable regenerative potential
doi.org/10.1242/dev....
October 30, 2025 at 3:40 PM
More extraordinary model systems for regeneration
In their #LifelongDevSI Perspective, José Garcıa-Arraras, Chunyi Li, Tania Rozario, Mansi Srivastava & @andrewilloughb.bsky.social introduce five research organisms with remarkable regenerative potential
doi.org/10.1242/dev....
In their #LifelongDevSI Perspective, José Garcıa-Arraras, Chunyi Li, Tania Rozario, Mansi Srivastava & @andrewilloughb.bsky.social introduce five research organisms with remarkable regenerative potential
doi.org/10.1242/dev....
Reposted by Shefali
“I never imagined that tiny fruit flies could reveal so much about the brain and its functions until I spent my summer in @alexgouldlab.bsky.social laboratory…” 🪰
Learn more about Padmapriya Ajith’ studentship experience @crick.ac.uk #RosaBeddingtonFund ⬇️
thenode.biologists.com/role-of-fat-...
Learn more about Padmapriya Ajith’ studentship experience @crick.ac.uk #RosaBeddingtonFund ⬇️
thenode.biologists.com/role-of-fat-...
Role of fat body lipid transport in Drosophila neurodevelopment - the Node
I never imagined that tiny fruit flies could reveal so much about the brain and its functions until I spent my summer in Alex Gould’s laboratory at the
thenode.biologists.com
October 30, 2025 at 12:04 PM
“I never imagined that tiny fruit flies could reveal so much about the brain and its functions until I spent my summer in @alexgouldlab.bsky.social laboratory…” 🪰
Learn more about Padmapriya Ajith’ studentship experience @crick.ac.uk #RosaBeddingtonFund ⬇️
thenode.biologists.com/role-of-fat-...
Learn more about Padmapriya Ajith’ studentship experience @crick.ac.uk #RosaBeddingtonFund ⬇️
thenode.biologists.com/role-of-fat-...
Reposted by Shefali
www.science.org/doi/10.1126/... How astrocytes modulate neural circuits & behavior is a fundamental question. Amazing work led by Kevin in Marc Freeman’s lab to reveal octopamine-tyramine exposure enables astrocytes to respond to neurotransmitters by adrenergic gating.
October 29, 2025 at 8:19 AM
www.science.org/doi/10.1126/... How astrocytes modulate neural circuits & behavior is a fundamental question. Amazing work led by Kevin in Marc Freeman’s lab to reveal octopamine-tyramine exposure enables astrocytes to respond to neurotransmitters by adrenergic gating.