Pravrutha Raman
@pravrutharaman.bsky.social
👩🏾🔬,🐶👶🏽mom, immigrant 🇴🇲🇮🇳🇬🇧🇺🇸| curiosity-driven science | K99/R00 Fellow Malik+Tsukiyama labs | PhD, Jose lab | She/Her
Reposted by Pravrutha Raman
Ever wondered what the lonely histone H3C110 does? We found that it’s lost in many fungi. Adding it back boosts histone H3 copper reductase activity, rescues iron defects and modulates lifespan, suggesting an evolutionary tradeoff between these effects.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Histone H3 cysteine 110 enhances iron metabolism and modulates replicative life span in Saccharomyces cerevisiae
Histone H3 cysteine 110 enhances iron metabolism and modulates replicative life span in yeast.
www.science.org
April 11, 2025 at 9:43 PM
Ever wondered what the lonely histone H3C110 does? We found that it’s lost in many fungi. Adding it back boosts histone H3 copper reductase activity, rescues iron defects and modulates lifespan, suggesting an evolutionary tradeoff between these effects.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Pravrutha Raman
🔬 @claudiamcl.bsky.social and I both work to support the next generation of scientists and foster a scientifically aware public. We authored an Op-Ed for the @seattletimes-rss.bsky.social about what’s at stake for science-and science education-right now!
www.seattletimes.com/opinion/if-w...
www.seattletimes.com/opinion/if-w...
If we gut science, where will the discoveries of the future come from? | Op-Ed
The student in a lab today may one day shape public policy, develop treatments or discover the next lifesaving cure.
www.seattletimes.com
April 9, 2025 at 12:21 AM
🔬 @claudiamcl.bsky.social and I both work to support the next generation of scientists and foster a scientifically aware public. We authored an Op-Ed for the @seattletimes-rss.bsky.social about what’s at stake for science-and science education-right now!
www.seattletimes.com/opinion/if-w...
www.seattletimes.com/opinion/if-w...
Reposted by Pravrutha Raman
Two reminders for aspiring PhD candidates: April 3 is the information session, and April 11 is the application deadline. See below for more info.
Our team is going to answer student questions about our PhD program on 3 April! We have 25+ fully-funded positions in this call. Pass on or share with your colleagues! Sign up here
ow.ly/ptFT50PNJV2
ow.ly/ptFT50PNJV2
April 2, 2025 at 7:50 AM
Two reminders for aspiring PhD candidates: April 3 is the information session, and April 11 is the application deadline. See below for more info.
Reposted by Pravrutha Raman
Proud of this work, led by the amazing Jeannette Tenthorey (now Assistant Professor at UCSF), demonstrating the adaptive power of single indel mutations in host-virus arms races, but a little sad that this is the coda to her amazing postdoc in the Malik & Emerman labs.
www.cell.com/cell-genomic...
www.cell.com/cell-genomic...
Indels allow antiviral proteins to evolve functional novelty inaccessible by missense mutations
Tenthorey et al. compare the effects of missense and indel mutations on the acquisition
of functional novelty by the rapidly evolving antiviral protein TRIM5α. They find
that single indel mutations al...
www.cell.com
March 27, 2025 at 9:36 PM
Proud of this work, led by the amazing Jeannette Tenthorey (now Assistant Professor at UCSF), demonstrating the adaptive power of single indel mutations in host-virus arms races, but a little sad that this is the coda to her amazing postdoc in the Malik & Emerman labs.
www.cell.com/cell-genomic...
www.cell.com/cell-genomic...
Reposted by Pravrutha Raman
Welcome to the home of #labdaptations ! My name is Kat and I am a Genetics PhD student, navigating science with a disability. Early in my grad school journey, I discovered that accessible lab equipment/tools were lacking, making it difficult for me to perform experiments.
March 25, 2025 at 10:45 PM
Welcome to the home of #labdaptations ! My name is Kat and I am a Genetics PhD student, navigating science with a disability. Early in my grad school journey, I discovered that accessible lab equipment/tools were lacking, making it difficult for me to perform experiments.
Reposted by Pravrutha Raman
Peer review completed within 7 days!
Paying peer reviewers!
Yes, it's possible.
Fast & Fair peer review by @biologyopen.bsky.social
More innovation from @biologists.bsky.social
Details here: www.biorxiv.org/content/10.1...
Paying peer reviewers!
Yes, it's possible.
Fast & Fair peer review by @biologyopen.bsky.social
More innovation from @biologists.bsky.social
Details here: www.biorxiv.org/content/10.1...
March 25, 2025 at 12:05 PM
Peer review completed within 7 days!
Paying peer reviewers!
Yes, it's possible.
Fast & Fair peer review by @biologyopen.bsky.social
More innovation from @biologists.bsky.social
Details here: www.biorxiv.org/content/10.1...
Paying peer reviewers!
Yes, it's possible.
Fast & Fair peer review by @biologyopen.bsky.social
More innovation from @biologists.bsky.social
Details here: www.biorxiv.org/content/10.1...
Reposted by Pravrutha Raman
Very excited for Fast & Fair peer review - authors get decisions, with reviews, within 7 business days of submission. Reviews are high quality - lots of quality control by our academic editors, plus we pay reviewers.
We are excited to be launching the next phase of our Fast & Fair peer review initiative: offering high-quality peer review within 7 working days. #fastandfairpeerreview
Read the Editorial by EiC Daniel Gorelick @danielgorelick.bsky.social at: bit.ly/4kYD1mL
Read the Editorial by EiC Daniel Gorelick @danielgorelick.bsky.social at: bit.ly/4kYD1mL
March 25, 2025 at 11:25 AM
Very excited for Fast & Fair peer review - authors get decisions, with reviews, within 7 business days of submission. Reviews are high quality - lots of quality control by our academic editors, plus we pay reviewers.
Reposted by Pravrutha Raman
🚨 HUGE news from Canada's tricouncils who are harmonizing their scholarship & fellowship programs, upping the total number (huzzah!), and critically, allowing foreigners to apply for doctoral and postdoc fellowships. Want to work with me? Get in touch! 🇨🇦🧪⚒️
www.nserc-crsng.gc.ca/NewsDetail-D...
www.nserc-crsng.gc.ca/NewsDetail-D...
NSERC - Latest News - Launch of the new Harmonized Tri-agency Scholarship and Fellowship programs
As announced in Budget 2024, the scholarship and fellowship programs administered by the three federal research funding agencies – the Canadian Institutes of Health Research (CIHR), the Natural Sciences and Engineering Research Council (NSERC), and the Social Sciences and Humanities Research Council (SSHRC) – have been streamlined into a new harmonized talent program called the Canada Research Training Awards Suite (CRTAS) that will open for applications in summer 2025.
www.nserc-crsng.gc.ca
March 14, 2025 at 7:20 PM
🚨 HUGE news from Canada's tricouncils who are harmonizing their scholarship & fellowship programs, upping the total number (huzzah!), and critically, allowing foreigners to apply for doctoral and postdoc fellowships. Want to work with me? Get in touch! 🇨🇦🧪⚒️
www.nserc-crsng.gc.ca/NewsDetail-D...
www.nserc-crsng.gc.ca/NewsDetail-D...
Reposted by Pravrutha Raman
Reposted by Pravrutha Raman
Walz: "The idea that the secretary of education would not know what IDEA is -- individuals with disability in education act -- that's like your mechanic not knowing how to put air in your tire. And she's in charge of this nation's education progress. It is catastrophic."
March 13, 2025 at 12:35 AM
Walz: "The idea that the secretary of education would not know what IDEA is -- individuals with disability in education act -- that's like your mechanic not knowing how to put air in your tire. And she's in charge of this nation's education progress. It is catastrophic."
Reposted by Pravrutha Raman
Keep calling!
AZ, CO, GA, MI, NH, PA, VA scientists: call wavering reps NOW
AZ Gallego 202-224-4521 & Kelly 202-224-2235
CO Bennet 202-224-5852 & Hickenlooper 202-224-5941
GA Ossoff 202-224-3521
NH Hassan 202-224-3324
M: Peters 202-224-6221 & Slotkin 202-224-4822
PA Fetterman 202-224-4254
VA Warner 202-224-2023
AZ Gallego 202-224-4521 & Kelly 202-224-2235
CO Bennet 202-224-5852 & Hickenlooper 202-224-5941
GA Ossoff 202-224-3521
NH Hassan 202-224-3324
M: Peters 202-224-6221 & Slotkin 202-224-4822
PA Fetterman 202-224-4254
VA Warner 202-224-2023
You've made 4,000 calls to your Senators to oppose the CR in the last *35 minutes* alone!! 🔥📞🔥
Keep up the pressure 👉 5calls.org/issue/cr-con...
Keep up the pressure 👉 5calls.org/issue/cr-con...
March 12, 2025 at 11:24 PM
Keep calling!
Reposted by Pravrutha Raman
AZ, CO, GA, MI, NH, PA, VA scientists: call wavering reps NOW
AZ Gallego 202-224-4521 & Kelly 202-224-2235
CO Bennet 202-224-5852 & Hickenlooper 202-224-5941
GA Ossoff 202-224-3521
NH Hassan 202-224-3324
M: Peters 202-224-6221 & Slotkin 202-224-4822
PA Fetterman 202-224-4254
VA Warner 202-224-2023
AZ Gallego 202-224-4521 & Kelly 202-224-2235
CO Bennet 202-224-5852 & Hickenlooper 202-224-5941
GA Ossoff 202-224-3521
NH Hassan 202-224-3324
M: Peters 202-224-6221 & Slotkin 202-224-4822
PA Fetterman 202-224-4254
VA Warner 202-224-2023
You've made 4,000 calls to your Senators to oppose the CR in the last *35 minutes* alone!! 🔥📞🔥
Keep up the pressure 👉 5calls.org/issue/cr-con...
Keep up the pressure 👉 5calls.org/issue/cr-con...
No Federal Funding CR Without DOGE Guardrails - Passed House ⭑ 5 Calls
UPDATE (03/11/25): The House has passed the GOP continuing resolution with a narrow 217-213 vote. The legislation now moves to the Senate where …
5calls.org
March 12, 2025 at 6:30 PM
AZ, CO, GA, MI, NH, PA, VA scientists: call wavering reps NOW
AZ Gallego 202-224-4521 & Kelly 202-224-2235
CO Bennet 202-224-5852 & Hickenlooper 202-224-5941
GA Ossoff 202-224-3521
NH Hassan 202-224-3324
M: Peters 202-224-6221 & Slotkin 202-224-4822
PA Fetterman 202-224-4254
VA Warner 202-224-2023
AZ Gallego 202-224-4521 & Kelly 202-224-2235
CO Bennet 202-224-5852 & Hickenlooper 202-224-5941
GA Ossoff 202-224-3521
NH Hassan 202-224-3324
M: Peters 202-224-6221 & Slotkin 202-224-4822
PA Fetterman 202-224-4254
VA Warner 202-224-2023
Reposted by Pravrutha Raman
Worm friends: The C. elegans Community Mentor Match Program is signing up mentees!
Click on the link to be matched with a mentor and/or to join a peer-mentoring group.
Please spread the word, and share with your lab members and worm friends! 📢
1/n
Click on the link to be matched with a mentor and/or to join a peer-mentoring group.
Please spread the word, and share with your lab members and worm friends! 📢
1/n
Mentee sign-up for the 2025 C. elegans Community Mentor Match program
The 2025 C. elegans Community Mentor Match is open to graduate students, postdocs, and faculty at any career stage. This survey collects information to help the committee (a) identify the most appropr...
forms.gle
March 12, 2025 at 8:31 PM
Worm friends: The C. elegans Community Mentor Match Program is signing up mentees!
Click on the link to be matched with a mentor and/or to join a peer-mentoring group.
Please spread the word, and share with your lab members and worm friends! 📢
1/n
Click on the link to be matched with a mentor and/or to join a peer-mentoring group.
Please spread the word, and share with your lab members and worm friends! 📢
1/n
Reposted by Pravrutha Raman
Today is the 35th anniversary of the Capitol Crawl, in which disabled activists discarded their mobility aids at the foot of the Capitol steps to climb them in support of passage of the Americans with Disabilities Ac. Jennifer Keelan-Chaffins, 8, told reporters "I'll take all night if I have to!"
March 12, 2025 at 1:35 PM
Today is the 35th anniversary of the Capitol Crawl, in which disabled activists discarded their mobility aids at the foot of the Capitol steps to climb them in support of passage of the Americans with Disabilities Ac. Jennifer Keelan-Chaffins, 8, told reporters "I'll take all night if I have to!"
Reposted by Pravrutha Raman
We have a 4-year fully funded PhD position available! Research topics include but are not limited to 1) Parallel evolution of climate adaptation in Europe and South America 2) The genetic architecture of temperature adaptation 3) The evolution of pathogenicity su.varbi.com/en/what:job/...
PhD student in Evolutionary Genomics with Yeast
The Department of Zoology of Stockholm University includes ca. 80 employees, including researchers, PhD students, and administrative staff. Research and education at the department occurs in an intern
su.varbi.com
March 10, 2025 at 11:41 AM
We have a 4-year fully funded PhD position available! Research topics include but are not limited to 1) Parallel evolution of climate adaptation in Europe and South America 2) The genetic architecture of temperature adaptation 3) The evolution of pathogenicity su.varbi.com/en/what:job/...
Reposted by Pravrutha Raman
Hey #Drosophila sky, wondering about tools:
I'm interested in any UAS-GFP or UAS-RFP lines on chr 2 or 3. I have a UAS-mCD8::GFP and UAS-mCD8::RFP from the 2000s, but they're both a bit weak. Wondering if there are better UAS-eGFP or UAS-DsRed lines made?
And next question: can you send them? 😅❤️
I'm interested in any UAS-GFP or UAS-RFP lines on chr 2 or 3. I have a UAS-mCD8::GFP and UAS-mCD8::RFP from the 2000s, but they're both a bit weak. Wondering if there are better UAS-eGFP or UAS-DsRed lines made?
And next question: can you send them? 😅❤️
March 12, 2025 at 9:56 AM
Hey #Drosophila sky, wondering about tools:
I'm interested in any UAS-GFP or UAS-RFP lines on chr 2 or 3. I have a UAS-mCD8::GFP and UAS-mCD8::RFP from the 2000s, but they're both a bit weak. Wondering if there are better UAS-eGFP or UAS-DsRed lines made?
And next question: can you send them? 😅❤️
I'm interested in any UAS-GFP or UAS-RFP lines on chr 2 or 3. I have a UAS-mCD8::GFP and UAS-mCD8::RFP from the 2000s, but they're both a bit weak. Wondering if there are better UAS-eGFP or UAS-DsRed lines made?
And next question: can you send them? 😅❤️
Reposted by Pravrutha Raman
A dear friend of mine just had all her funding pulled. All she has ever done is work exceptionally hard to do excellent science and help others do great science. This is heartbreaking
March 11, 2025 at 2:40 AM
A dear friend of mine just had all her funding pulled. All she has ever done is work exceptionally hard to do excellent science and help others do great science. This is heartbreaking
Reposted by Pravrutha Raman
I was that woman! I have frequently told the story of how Jeremy responded after my second NIH rejection. He said, “Whatever you do, don’t stop spending. If you run out of startup, we’ll find more money for you.” I didn’t need it in the end, but knowing he had my back was huge. Thank you!
Our first recruit struggled initially to succeed in obtaining NIH funding. But her science was/is terrific and we bridged her along. She subsequent received an HHMI appointment, and then substantial NIH funding. She is now a member of the National Academy and is the current department director
25/n
25/n
March 9, 2025 at 4:14 PM
I was that woman! I have frequently told the story of how Jeremy responded after my second NIH rejection. He said, “Whatever you do, don’t stop spending. If you run out of startup, we’ll find more money for you.” I didn’t need it in the end, but knowing he had my back was huge. Thank you!
Reposted by Pravrutha Raman
Mandatory high school civics class that isn’t just like “how a bill becomes law” or whatever but also “how NOAA powers your phone’s weather app” and “NIH helped make your asthma inhaler”
March 8, 2025 at 12:03 PM
Mandatory high school civics class that isn’t just like “how a bill becomes law” or whatever but also “how NOAA powers your phone’s weather app” and “NIH helped make your asthma inhaler”
Reposted by Pravrutha Raman
From DC.
The drawing is of the famous research worm C. elegans, in which microRNAs were discovered.
C. elegans has neither a brain nor a spine. 🧪
The drawing is of the famous research worm C. elegans, in which microRNAs were discovered.
C. elegans has neither a brain nor a spine. 🧪
March 8, 2025 at 3:22 AM
From DC.
The drawing is of the famous research worm C. elegans, in which microRNAs were discovered.
C. elegans has neither a brain nor a spine. 🧪
The drawing is of the famous research worm C. elegans, in which microRNAs were discovered.
C. elegans has neither a brain nor a spine. 🧪
Reposted by Pravrutha Raman
Congrats to Jeremy Hollis, a graduate research assistant in the @melodygcampbell.bsky.social Lab at Fred Hutch, on receiving the 2025 Weintraub Award for excellence in the biological sciences! Read more: bit.ly/41rXJ5q
March 7, 2025 at 9:46 PM
Congrats to Jeremy Hollis, a graduate research assistant in the @melodygcampbell.bsky.social Lab at Fred Hutch, on receiving the 2025 Weintraub Award for excellence in the biological sciences! Read more: bit.ly/41rXJ5q
Reposted by Pravrutha Raman
Standing up for science in Philly!
March 7, 2025 at 5:56 PM
Standing up for science in Philly!
Reposted by Pravrutha Raman
Standing up for science in Seattle
March 7, 2025 at 8:40 PM
Standing up for science in Seattle
Reposted by Pravrutha Raman
New Jersey is standing up for science!!
But the fight isn’t over - now it’s time to get in the faces of our reps and force them to fight for us. As @samwang.bsky.social said, neuroscience tells us that
1) As social creatures, putting a face to the cause makes it memorable
#StandUpForScience2025
But the fight isn’t over - now it’s time to get in the faces of our reps and force them to fight for us. As @samwang.bsky.social said, neuroscience tells us that
1) As social creatures, putting a face to the cause makes it memorable
#StandUpForScience2025
March 7, 2025 at 8:44 PM
New Jersey is standing up for science!!
But the fight isn’t over - now it’s time to get in the faces of our reps and force them to fight for us. As @samwang.bsky.social said, neuroscience tells us that
1) As social creatures, putting a face to the cause makes it memorable
#StandUpForScience2025
But the fight isn’t over - now it’s time to get in the faces of our reps and force them to fight for us. As @samwang.bsky.social said, neuroscience tells us that
1) As social creatures, putting a face to the cause makes it memorable
#StandUpForScience2025
Reposted by Pravrutha Raman
More #standupforscience2025 Trenton. What do nerds do? Stick together! 600 plus nerds! @annikabarber.bsky.social @samwang.bsky.social @rburdine1.bsky.social @cate-cholamine.bsky.social @schindlerlab.bsky.social
March 7, 2025 at 7:25 PM
More #standupforscience2025 Trenton. What do nerds do? Stick together! 600 plus nerds! @annikabarber.bsky.social @samwang.bsky.social @rburdine1.bsky.social @cate-cholamine.bsky.social @schindlerlab.bsky.social