Cynthia Wolberger
@cwolberger.bsky.social
Professor and Director, Dept. of Biophysics & Biophysical Chemistry
Johns Hopkins School of Medicine, structural biologist, lover of chromatin and ubiquitin, fan of the active voice.
Johns Hopkins School of Medicine, structural biologist, lover of chromatin and ubiquitin, fan of the active voice.
Get this over with already so we can see the figure skating.
February 9, 2026 at 1:27 AM
Get this over with already so we can see the figure skating.
Reposted by Cynthia Wolberger
It is with deep sadness that we share that Michael J. Matunis, a professor in the Department of Biochemistry and Molecular Biology, has passed away. (1/4)
In Memoriam: Michael Matunis, 1964-2026 | Johns Hopkins Bloomberg School of Public Health
publichealth.jhu.edu
February 4, 2026 at 7:50 PM
It is with deep sadness that we share that Michael J. Matunis, a professor in the Department of Biochemistry and Molecular Biology, has passed away. (1/4)
Reposted by Cynthia Wolberger
Engineering Light-Responsive Transcription Factors via Strategic Masking of Post-translational Modification Residues
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
Engineering Light-Responsive Transcription Factors via Strategic Masking of Post-translational Modification Residues
The development of synthetic transcription factors (TFs) that generate functional outputs in response to specific stimuli holds significant promise for modulating key cellular processes in both basic ...
pubs.acs.org
January 27, 2026 at 6:13 PM
Engineering Light-Responsive Transcription Factors via Strategic Masking of Post-translational Modification Residues
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
On International Holocaust Remembrance Day I remember my grandmother, Cywia Wolberger, and aunts, Aliza and Perel Wolberger, who were murdered in the Warsaw Ghetto. Never again.
January 27, 2026 at 6:13 PM
On International Holocaust Remembrance Day I remember my grandmother, Cywia Wolberger, and aunts, Aliza and Perel Wolberger, who were murdered in the Warsaw Ghetto. Never again.
Let’s see what @charlesmbrenner.bsky.social has to say about this…..
Wanna see real-life miracles? Fund scientific research.
A team of US scientists just cured Alzheimer’s in mice — and there is now hope that the disease can be reversed in humans.
futurism.com/health-medic...
A team of US scientists just cured Alzheimer’s in mice — and there is now hope that the disease can be reversed in humans.
futurism.com/health-medic...
Alzheimer's Fully Reversed in Mice, Scientists Say
A new compound has been shown to reverse late stage Alzheimer's disease in lab mice, which gives millions of sufferers new cause for hope.
futurism.com
December 31, 2025 at 12:00 PM
Let’s see what @charlesmbrenner.bsky.social has to say about this…..
For a few moments of distraction in these trying times, check out the Cheetah Cub Cam at the Smithsonian Conservation Biology Institute:
nationalzoo.si.edu/webcams/chee...
nationalzoo.si.edu/webcams/chee...
Cheetah Cub Cam
The Cheetah Cub Cam streams live from the Smithsonian Conservation Biology Institute in Front Royal, Virginia.
nationalzoo.si.edu
November 25, 2025 at 1:51 AM
For a few moments of distraction in these trying times, check out the Cheetah Cub Cam at the Smithsonian Conservation Biology Institute:
nationalzoo.si.edu/webcams/chee...
nationalzoo.si.edu/webcams/chee...
I am going to scream if one more person sends me a schedule but calls it an "itinerary."
itinerary = planned route or journey, or a document recording it. It is from the Latin, "itinerarium," which means route of travel.
Please spread the word!!
itinerary = planned route or journey, or a document recording it. It is from the Latin, "itinerarium," which means route of travel.
Please spread the word!!
November 7, 2025 at 1:49 PM
I am going to scream if one more person sends me a schedule but calls it an "itinerary."
itinerary = planned route or journey, or a document recording it. It is from the Latin, "itinerarium," which means route of travel.
Please spread the word!!
itinerary = planned route or journey, or a document recording it. It is from the Latin, "itinerarium," which means route of travel.
Please spread the word!!
Apply now to join the Johns Hopkins Program in Molecular Biophysics! Our interdisciplinary Ph.D. program trains students to explore the physical principles underlying biology — from molecules to cells. Open to both U.S. and international applicants. Application deadline Dec. 1 : pmb.jhu.edu
Home | Program in Molecular Biophysics
The Program in Molecular Biophysics (PMB) trains PhD students to do cutting-edge biophysics research using the methods of biology, biochemistry, chemistry, physics, engineering, and computer science.
pmb.jhu.edu
November 3, 2025 at 10:14 PM
Apply now to join the Johns Hopkins Program in Molecular Biophysics! Our interdisciplinary Ph.D. program trains students to explore the physical principles underlying biology — from molecules to cells. Open to both U.S. and international applicants. Application deadline Dec. 1 : pmb.jhu.edu
I’ve been enjoying your drawings but especially love this one ! 💕
This October I’m drawing 1 molecule a day inspired by proteins in pdb @rcsbpdb.bsky.social
Day 20/31
Prompt RIVALS
Pdb: 8V27 & 8G6S
Two rival histone modifications on a nucleosome. Ubiquitination of H2BK120 activates genes while H2AK119 represses them.
Next: BLAST
Suggestions?
Day 20/31
Prompt RIVALS
Pdb: 8V27 & 8G6S
Two rival histone modifications on a nucleosome. Ubiquitination of H2BK120 activates genes while H2AK119 represses them.
Next: BLAST
Suggestions?
November 2, 2025 at 7:37 PM
I’ve been enjoying your drawings but especially love this one ! 💕
Because sometimes we just need a laugh:
October 24, 2025 at 5:48 PM
Because sometimes we just need a laugh:
Reposted by Cynthia Wolberger
Chemical Engineering of Transcription Factors Uncovered Cell-Permeable μMax Modulators l @jacs.acspublications.org
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
Chemical Engineering of Transcription Factors Uncovered Cell-Permeable μMax Modulators
Transcription factor engineering has emerged as a powerful strategy for generating novel proteins for fundamental research and biomedical applications. Although various analogs have been developed, th...
pubs.acs.org
October 15, 2025 at 6:44 PM
Chemical Engineering of Transcription Factors Uncovered Cell-Permeable μMax Modulators l @jacs.acspublications.org
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
Reposted by Cynthia Wolberger
Prof. Jasmina Wiemann has been selected for a prestigious Packard fellowship. This the first recognition of a paleobiologist by the Foundation!
That is 8 Packard Fellows in 6 years for Johns Hopkins University.
Prof. Wiemann's website is the stuff of movies: www.jasminawiemann.com
That is 8 Packard Fellows in 6 years for Johns Hopkins University.
Prof. Wiemann's website is the stuff of movies: www.jasminawiemann.com
October 15, 2025 at 1:54 PM
Prof. Jasmina Wiemann has been selected for a prestigious Packard fellowship. This the first recognition of a paleobiologist by the Foundation!
That is 8 Packard Fellows in 6 years for Johns Hopkins University.
Prof. Wiemann's website is the stuff of movies: www.jasminawiemann.com
That is 8 Packard Fellows in 6 years for Johns Hopkins University.
Prof. Wiemann's website is the stuff of movies: www.jasminawiemann.com
Reposted by Cynthia Wolberger
This is, without any exaggeration, exactly how Putin and Orbán proceeded — using antisemitism to discredit the idea of civil society and political opposition, and as an excuse to undo the rule of law.
www.nytimes.com/2025/09/25/u...
www.nytimes.com/2025/09/25/u...
Justice Dept. Official Pushes Prosecutors to Investigate George Soros’s Foundation
www.nytimes.com
September 25, 2025 at 4:14 PM
This is, without any exaggeration, exactly how Putin and Orbán proceeded — using antisemitism to discredit the idea of civil society and political opposition, and as an excuse to undo the rule of law.
www.nytimes.com/2025/09/25/u...
www.nytimes.com/2025/09/25/u...
Reposted by Cynthia Wolberger
Reposted by Cynthia Wolberger
Reposted by Cynthia Wolberger
🚨🧠🔬 A major breakthrough in molecular neuroscience:
I am excited to share a new story from our lab, published in accelerated format today by @nature.com:
"Delta-type glutamate receptors are ligand-gated ion channels"
Read more here (free article link): rdcu.be/eGIKz
I am excited to share a new story from our lab, published in accelerated format today by @nature.com:
"Delta-type glutamate receptors are ligand-gated ion channels"
Read more here (free article link): rdcu.be/eGIKz
September 16, 2025 at 4:47 PM
🚨🧠🔬 A major breakthrough in molecular neuroscience:
I am excited to share a new story from our lab, published in accelerated format today by @nature.com:
"Delta-type glutamate receptors are ligand-gated ion channels"
Read more here (free article link): rdcu.be/eGIKz
I am excited to share a new story from our lab, published in accelerated format today by @nature.com:
"Delta-type glutamate receptors are ligand-gated ion channels"
Read more here (free article link): rdcu.be/eGIKz
A giant in molecular biology and virology has passed. RIP David Baltimore.
www.nytimes.com/2025/09/07/s...
www.nytimes.com/2025/09/07/s...
David Baltimore, Nobel-Winning Molecular Biologist, Dies at 87
www.nytimes.com
September 8, 2025 at 2:02 AM
A giant in molecular biology and virology has passed. RIP David Baltimore.
www.nytimes.com/2025/09/07/s...
www.nytimes.com/2025/09/07/s...
Reposted by Cynthia Wolberger
Reposted by Cynthia Wolberger
shocking to read over and over the stories of close colleagues who can't run their lab anymore. I know Karen well and it's heartbreaking. Also #PIinthelab! www.washingtonpost.com/education/20...
Harvard’s research is shrinking amid the Trump administration’s freeze
Even if grants at Harvard are suddenly restored, there is deep-rooted uncertainty about the damage already done and the future of basic science research in the U.S.
www.washingtonpost.com
August 25, 2025 at 7:42 PM
shocking to read over and over the stories of close colleagues who can't run their lab anymore. I know Karen well and it's heartbreaking. Also #PIinthelab! www.washingtonpost.com/education/20...
Reposted by Cynthia Wolberger
These are the most challenging times for early-career scientists and engineers.
My team is doing its bit to help by maintaining and even expanding our database of funding opportunities for early-career researchers.
We found 437 of them.
Download it freely here: research.jhu.edu/rdt/funding-...
My team is doing its bit to help by maintaining and even expanding our database of funding opportunities for early-career researchers.
We found 437 of them.
Download it freely here: research.jhu.edu/rdt/funding-...
August 11, 2025 at 11:54 AM
These are the most challenging times for early-career scientists and engineers.
My team is doing its bit to help by maintaining and even expanding our database of funding opportunities for early-career researchers.
We found 437 of them.
Download it freely here: research.jhu.edu/rdt/funding-...
My team is doing its bit to help by maintaining and even expanding our database of funding opportunities for early-career researchers.
We found 437 of them.
Download it freely here: research.jhu.edu/rdt/funding-...
Reposted by Cynthia Wolberger
On Sept 30 in Baltimore MD I will deliver the annual Michael Klag and Lucy Meoni Lecture at Johns Hopkins Bloomberg School of Public Health @johnshopkinssph.bsky.social
publichealth.jhu.edu/events/2025/...
publichealth.jhu.edu/events/2025/...
Global Vaccines and Immunizations in a Time of Global Boiling, Megacities, and Anti-Science | Johns Hopkins Bloomberg School of Public Health
publichealth.jhu.edu
August 7, 2025 at 11:02 AM
On Sept 30 in Baltimore MD I will deliver the annual Michael Klag and Lucy Meoni Lecture at Johns Hopkins Bloomberg School of Public Health @johnshopkinssph.bsky.social
publichealth.jhu.edu/events/2025/...
publichealth.jhu.edu/events/2025/...
Reposted by Cynthia Wolberger
See our new article in Structure! Sub-3 Å resolution protein structure determination by single-particle #cryoEM at 100 keV. Really exciting results with 100kV Tundra Cryo-TEM.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Sub-3 Å resolution protein structure determination by single-particle cryo-EM at 100 keV
Cryoelectron microscopy (cryo-EM) has transformed structural biology by providing high-resolution insights into biological macromolecules. We report s…
www.sciencedirect.com
July 31, 2025 at 8:38 PM
See our new article in Structure! Sub-3 Å resolution protein structure determination by single-particle #cryoEM at 100 keV. Really exciting results with 100kV Tundra Cryo-TEM.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Cynthia Wolberger
Absolutely outrageous interference in NIH extramural funding by OMB dropping this evening. Damaging to our nation’s world leadership, innovation, and training today and for years in the future. www.wsj.com/politics/pol...
Trump Administration Puts New Chokehold on Billions in Health-Research Funding
The National Institutes of Health can’t award grants to outside researchers under a new White House restriction.
www.wsj.com
July 30, 2025 at 12:45 AM
Absolutely outrageous interference in NIH extramural funding by OMB dropping this evening. Damaging to our nation’s world leadership, innovation, and training today and for years in the future. www.wsj.com/politics/pol...
Reposted by Cynthia Wolberger
#cryoEM confluence in Munich #womeninSTEM
July 17, 2025 at 9:44 PM
#cryoEM confluence in Munich #womeninSTEM
Reposted by Cynthia Wolberger
Powerful story from Kate Zernike from the NYT
Covers the diversity of young scientists targeted by the anti-DEI BS. Definitely worth a read and a share.
[Gift link]
www.nytimes.com/2025/07/10/u...
Covers the diversity of young scientists targeted by the anti-DEI BS. Definitely worth a read and a share.
[Gift link]
www.nytimes.com/2025/07/10/u...
The Surprising Scientists Hit by Trump’s D.E.I. Cuts
www.nytimes.com
July 10, 2025 at 5:53 PM
Powerful story from Kate Zernike from the NYT
Covers the diversity of young scientists targeted by the anti-DEI BS. Definitely worth a read and a share.
[Gift link]
www.nytimes.com/2025/07/10/u...
Covers the diversity of young scientists targeted by the anti-DEI BS. Definitely worth a read and a share.
[Gift link]
www.nytimes.com/2025/07/10/u...