Maxime Rousseaux
@maximewc.bsky.social
Associate Professor and CRC studying protein mislocalization, neurodegeneration and functional genomics at uOttawa Brain and Mind Research Institute and co-director of Genome Editing and Molecular biology core at uOttawa
Very fun collaborating with the Russell lab on this one. Tireless efforts of Dr. Truc (Cloe) Losier to bring this across the finish line.
Identification of organelle-specific #autophagy regulators from tandem #CRISPR screens. New study from Truc Losier, Karyn King, Maxime Rousseaux, and Ryan Russell (@russellbiolab.bsky.social) @uottawa.ca: rupress.org/jcb/article/...
#Biochemistry #CellSignaling
#Biochemistry #CellSignaling
August 29, 2025 at 1:17 AM
Very fun collaborating with the Russell lab on this one. Tireless efforts of Dr. Truc (Cloe) Losier to bring this across the finish line.
Reposted by Maxime Rousseaux
Excited to share our new autophagy resource here, a dataset directly contrasting kinase regulators of bulk or organelle-specific autophagy. Look at the results for your gene/organelle of interest or get ideas for your own parallel screen. #autophagy #CRISPR #functionalgenomics
Losier, Russell et al. @uottawa.ca identify distinct kinase signaling pathways that differentially regulate bulk and selective #autophagy. Using kinome-wide #CRISPR screening, they reveal both shared and pathway-specific regulators rupress.org/jcb/article/...
August 27, 2025 at 1:59 PM
Excited to share our new autophagy resource here, a dataset directly contrasting kinase regulators of bulk or organelle-specific autophagy. Look at the results for your gene/organelle of interest or get ideas for your own parallel screen. #autophagy #CRISPR #functionalgenomics
Reposted by Maxime Rousseaux
Reposted by Maxime Rousseaux
Losier, Russell et al. @uottawa.ca identify distinct kinase signaling pathways that differentially regulate bulk and selective #autophagy. Using kinome-wide #CRISPR screening, they reveal both shared and pathway-specific regulators rupress.org/jcb/article/...
August 21, 2025 at 4:02 PM
Losier, Russell et al. @uottawa.ca identify distinct kinase signaling pathways that differentially regulate bulk and selective #autophagy. Using kinome-wide #CRISPR screening, they reveal both shared and pathway-specific regulators rupress.org/jcb/article/...
Reposted by Maxime Rousseaux
Good morning #university students in Canada!
📢 Spread the word; you can #VoteOnCampus April 13-16.
#VoteScience🇨🇦 #VoterRecherche #VotonsRecherche #ResearchersVote
#Elxn45
🎁
www.theglobeandmail.com/gift/c231c7b...
📢 Spread the word; you can #VoteOnCampus April 13-16.
#VoteScience🇨🇦 #VoterRecherche #VotonsRecherche #ResearchersVote
#Elxn45
🎁
www.theglobeandmail.com/gift/c231c7b...
Campus polls open at universities and colleges across Canada
Elections Canada spokesperson Serge Fleyfel said the on-campus polling stations are part of the agency’s efforts to make casting a ballot easier for younger voters
www.theglobeandmail.com
April 14, 2025 at 1:20 PM
Good morning #university students in Canada!
📢 Spread the word; you can #VoteOnCampus April 13-16.
#VoteScience🇨🇦 #VoterRecherche #VotonsRecherche #ResearchersVote
#Elxn45
🎁
www.theglobeandmail.com/gift/c231c7b...
📢 Spread the word; you can #VoteOnCampus April 13-16.
#VoteScience🇨🇦 #VoterRecherche #VotonsRecherche #ResearchersVote
#Elxn45
🎁
www.theglobeandmail.com/gift/c231c7b...
Thrilled to see our work published in its final form @Mol. Neurodegeneration. Outstanding work by @terryrsuk.bsky.social and colleagues. Please check-out the "skytorial" below. As always, happy to share reagents (plasmids are being put on @addgene.bsky.social ), mice and other data; just reach out!
We’re happy to share that our labs first #ALS and #FTD study “A stress-dependent TDP-43 SUMOylation program preserves neuronal function” is now online at Molecular Neurodegeneration! doi.org/10.1186/s130...
A stress-dependent TDP-43 SUMOylation program preserves neuronal function - Molecular Neurodegeneration
Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD) are overwhelmingly linked to TDP-43 dysfunction. Mutations in TDP-43 are rare, indicating that the progressive accumulation of exo...
doi.org
March 31, 2025 at 2:00 PM
Thrilled to see our work published in its final form @Mol. Neurodegeneration. Outstanding work by @terryrsuk.bsky.social and colleagues. Please check-out the "skytorial" below. As always, happy to share reagents (plasmids are being put on @addgene.bsky.social ), mice and other data; just reach out!
Reposted by Maxime Rousseaux
Looking for alternative non-US suppliers of lab reagents too. Would be great if someone had a list to share.
March 17, 2025 at 3:24 AM
Looking for alternative non-US suppliers of lab reagents too. Would be great if someone had a list to share.
Reposted by Maxime Rousseaux
To me, the worrying part about the push for more research on vaccines and autism isn’t that it’s a waste of money, it’s that those pushing for more research are also interested in seeing a specific result. And if they start messing w the process of science, that would send us down a really dark path
March 9, 2025 at 2:45 PM
To me, the worrying part about the push for more research on vaccines and autism isn’t that it’s a waste of money, it’s that those pushing for more research are also interested in seeing a specific result. And if they start messing w the process of science, that would send us down a really dark path
Reposted by Maxime Rousseaux
It’s pretty easy to “apply” for a PhD in Canada, and a little different from most US places, just send a cover letter, CV and undergrad transcript to a PI you’d like to work with. Put some effort into it, make sure you convey what you’re applying for and why.
Many US students don’t know how to seek opportunities outside the US. With some help from our colleagues in EU and Canada, we could put together a consolidated website of PhD opportunities and scholarships outside the US, organized by field. There might still be time for this year in some places.
I’m having similar conversations and sharing international opportunities a lot. I’m sure for a lot of US based trainees that feels overwhelming. I moved to Europe for my postdoc.Happy to chat with any trainees about my experience if it would be helpful.
March 1, 2025 at 2:33 PM
It’s pretty easy to “apply” for a PhD in Canada, and a little different from most US places, just send a cover letter, CV and undergrad transcript to a PI you’d like to work with. Put some effort into it, make sure you convey what you’re applying for and why.
Reposted by Maxime Rousseaux
With the craziness going on in the south, I am opening up a few postdoc positions in my lab. Contact me if interested. Those with experience in ethnic-racial marginalized families, peer relationships, EEG, and ILD are especially welcome! Please circulate, thx!!
February 20, 2025 at 5:38 PM
With the craziness going on in the south, I am opening up a few postdoc positions in my lab. Contact me if interested. Those with experience in ethnic-racial marginalized families, peer relationships, EEG, and ILD are especially welcome! Please circulate, thx!!
Reposted by Maxime Rousseaux
Did you ever think about how much time you spend *judging* as a scientist? Judging papers, research proposals, other scientists...
This onslaught of judging duties hit me hard as a new professor & I've written about the need to explicitly decide one's judging criteria here 👇
This onslaught of judging duties hit me hard as a new professor & I've written about the need to explicitly decide one's judging criteria here 👇
How to explore your scientific values and develop a vision for your field.
By @neurograce.bsky.social
www.thetransmitter.org/craft-and-ca...
How to explore your scientific values and develop a vision for your field
As a new professor, I was caught off guard by one part of the job: my role as an evaluator.
www.thetransmitter.org
May 3, 2024 at 4:09 PM
Did you ever think about how much time you spend *judging* as a scientist? Judging papers, research proposals, other scientists...
This onslaught of judging duties hit me hard as a new professor & I've written about the need to explicitly decide one's judging criteria here 👇
This onslaught of judging duties hit me hard as a new professor & I've written about the need to explicitly decide one's judging criteria here 👇
Reposted by Maxime Rousseaux
🎄PinkyCaMP- our christmas gift to you! 🎁: We are excited to present PinkyCaMP, the first mScarlet based calcium sensor with:
✨exceptional, brightness
✨phototability
✨and optogenetic compatability.
Check out our new preprint:
www.biorxiv.org/content/10.1...
✨exceptional, brightness
✨phototability
✨and optogenetic compatability.
Check out our new preprint:
www.biorxiv.org/content/10.1...
December 18, 2024 at 10:01 AM
🎄PinkyCaMP- our christmas gift to you! 🎁: We are excited to present PinkyCaMP, the first mScarlet based calcium sensor with:
✨exceptional, brightness
✨phototability
✨and optogenetic compatability.
Check out our new preprint:
www.biorxiv.org/content/10.1...
✨exceptional, brightness
✨phototability
✨and optogenetic compatability.
Check out our new preprint:
www.biorxiv.org/content/10.1...
Reposted by Maxime Rousseaux
In case any of my fellow creatives also needed this reminder:
November 16, 2024 at 1:12 AM
In case any of my fellow creatives also needed this reminder:
Reposted by Maxime Rousseaux
The preprint battle in neuroscience has gradually been won. I think the next step will be more dramatic -- a collapse in peer review resources to service each paper.
December 12, 2024 at 7:48 PM
The preprint battle in neuroscience has gradually been won. I think the next step will be more dramatic -- a collapse in peer review resources to service each paper.
Reposted by Maxime Rousseaux
Alpha-synuclein knockout impairs melanoma development and alters DNA damage repair in the TG3 mouse model in a sex-dependent manner https://www.biorxiv.org/content/10.1101/2024.12.01.626256v1
December 5, 2024 at 6:51 PM
Alpha-synuclein knockout impairs melanoma development and alters DNA damage repair in the TG3 mouse model in a sex-dependent manner https://www.biorxiv.org/content/10.1101/2024.12.01.626256v1
Reposted by Maxime Rousseaux
I will have space in my lab to supervise a new Ph.D. student and/or a postdoc to work on projects focussing on the role of the immune system in Parkinson's disease. Please share with potentially interested candidates.
November 26, 2024 at 11:03 PM
I will have space in my lab to supervise a new Ph.D. student and/or a postdoc to work on projects focussing on the role of the immune system in Parkinson's disease. Please share with potentially interested candidates.
Reposted by Maxime Rousseaux
Twitter used to be the second-highest source of traffic to protocols.io as researchers shared their public methods (highest was Google). Today, 0.1% of our monthly traffic is from Twitter.
I'm hopeful for the growth of the research community on Bluesky & sad about the senseless demise of Twitter.
I'm hopeful for the growth of the research community on Bluesky & sad about the senseless demise of Twitter.
November 20, 2024 at 7:31 PM
Twitter used to be the second-highest source of traffic to protocols.io as researchers shared their public methods (highest was Google). Today, 0.1% of our monthly traffic is from Twitter.
I'm hopeful for the growth of the research community on Bluesky & sad about the senseless demise of Twitter.
I'm hopeful for the growth of the research community on Bluesky & sad about the senseless demise of Twitter.
Reposted by Maxime Rousseaux
We are starting a search for senior and mid career researchers candidates for the Canada Excellence Research Chair Program. We have amazing infrastructure for research including state of the art microscopy (STED, lightsheet etc), 🐁 behavior and MRI facilities (new 15.2T for 🐁 ) mouse-trap.org
MouseTRAP – MouseTRAP is a distinctive platform that operates within Western University and is available to researchers on a fee-for-service basis. Various levels of support are available to users at ...
mouse-trap.org
November 16, 2024 at 12:36 AM
We are starting a search for senior and mid career researchers candidates for the Canada Excellence Research Chair Program. We have amazing infrastructure for research including state of the art microscopy (STED, lightsheet etc), 🐁 behavior and MRI facilities (new 15.2T for 🐁 ) mouse-trap.org
Reposted by Maxime Rousseaux
Download our database of 492 (!) funding opportunities for EARLY-CAREER FACULTY AND RESEARCHERS.
For each entry, we provide link to funder, description, amount, deadline, and eligibility criteria (e.g. citizenship).
Download freely here: research.jhu.edu/rdt/funding-...
For each entry, we provide link to funder, description, amount, deadline, and eligibility criteria (e.g. citizenship).
Download freely here: research.jhu.edu/rdt/funding-...
November 17, 2024 at 4:38 PM
Download our database of 492 (!) funding opportunities for EARLY-CAREER FACULTY AND RESEARCHERS.
For each entry, we provide link to funder, description, amount, deadline, and eligibility criteria (e.g. citizenship).
Download freely here: research.jhu.edu/rdt/funding-...
For each entry, we provide link to funder, description, amount, deadline, and eligibility criteria (e.g. citizenship).
Download freely here: research.jhu.edu/rdt/funding-...
Reposted by Maxime Rousseaux
Way to go Eve! My wonderful colleague, friend and mentor Eve Marder just won the National Medal of Science!
www.c-span.org/video/?53134...
www.c-span.org/video/?53134...
President Biden Awards National Medal of Science and National Medal of Technology and Innovation
www.c-span.org
October 24, 2023 at 4:54 PM
Way to go Eve! My wonderful colleague, friend and mentor Eve Marder just won the National Medal of Science!
www.c-span.org/video/?53134...
www.c-span.org/video/?53134...