@markpownall.bsky.social
Reposted
Since it's a tense time of year 🫠
December 24, 2025 at 8:35 AM
Since it's a tense time of year 🫠
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I don't always get pretty, isolated, AND transfected primary neurons in culture, but when I do I take advantage.... Rat hippocampal neuron overexpressing ThymosinB4-mScarlet and imaged for 16hr on a @zeiss-microscopy.bsky.social LSM880 with Airyscan. #FluorescenceFriday #Microscopy
December 19, 2025 at 2:01 PM
I don't always get pretty, isolated, AND transfected primary neurons in culture, but when I do I take advantage.... Rat hippocampal neuron overexpressing ThymosinB4-mScarlet and imaged for 16hr on a @zeiss-microscopy.bsky.social LSM880 with Airyscan. #FluorescenceFriday #Microscopy
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Felt a little festive at the microscope this morning for #FluorescenceFriday 🎄
Here’s the nervous system of a juvenile sea star ⭐️
Green = acetylated tubulin, red = nuclei
Happy holidays!
Here’s the nervous system of a juvenile sea star ⭐️
Green = acetylated tubulin, red = nuclei
Happy holidays!
December 19, 2025 at 5:32 PM
Felt a little festive at the microscope this morning for #FluorescenceFriday 🎄
Here’s the nervous system of a juvenile sea star ⭐️
Green = acetylated tubulin, red = nuclei
Happy holidays!
Here’s the nervous system of a juvenile sea star ⭐️
Green = acetylated tubulin, red = nuclei
Happy holidays!
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Second anniversary of our Apple TV’s spectacular attempt to understand me asking for “Hercule Poirot’s Christmas”
December 23, 2025 at 7:25 PM
Second anniversary of our Apple TV’s spectacular attempt to understand me asking for “Hercule Poirot’s Christmas”
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The jury is still out - and that's being generous- on whether Love Actually is a Christmas Film, but there's another seasonal Richard Curtis effort that's absolutely *brilliant* but you never, ever see anywhere now - Bernard And The Genie.
timworthington.org/2020/12/24/l...
timworthington.org/2020/12/24/l...
December 24, 2025 at 10:00 AM
The jury is still out - and that's being generous- on whether Love Actually is a Christmas Film, but there's another seasonal Richard Curtis effort that's absolutely *brilliant* but you never, ever see anywhere now - Bernard And The Genie.
timworthington.org/2020/12/24/l...
timworthington.org/2020/12/24/l...
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Happy unprecedented wave of super-flu season to those who fabulate.
December 23, 2025 at 11:49 AM
Happy unprecedented wave of super-flu season to those who fabulate.
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Right. Where's the discussion on "what does a good migration system look like from a centre-left perspective?"
Instead, look polls!, something, something working people.
Instead, look polls!, something, something working people.
December 22, 2025 at 7:40 AM
Right. Where's the discussion on "what does a good migration system look like from a centre-left perspective?"
Instead, look polls!, something, something working people.
Instead, look polls!, something, something working people.
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The 'betrayal of Brexit' response to rejoining Erasmus is obviously predictable, and stupid (Brexit = leaving EU). But what's more striking is how *dated* it seems, like someone still waving a 'Thatcher out' placard.
December 17, 2025 at 8:13 PM
The 'betrayal of Brexit' response to rejoining Erasmus is obviously predictable, and stupid (Brexit = leaving EU). But what's more striking is how *dated* it seems, like someone still waving a 'Thatcher out' placard.
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This legal action will be costing hundreds of thousands of pounds. It's economic warfare waged by a billionaire bigot against decent, tolerant people across the UK.
can someone please for the love of god tell me where i can see a trans woman? i want to career switch into litigation. ... attorney? what do you mean? no you dingus i'm going to be a professional plaintiff
December 14, 2025 at 11:56 AM
This legal action will be costing hundreds of thousands of pounds. It's economic warfare waged by a billionaire bigot against decent, tolerant people across the UK.
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Incredibly brave. Imagine the faceless bores the BBC will have making their programmes if they continue down this path.
Very sad that I felt I had no choice but to resign from The Infinite Monkey Cage - a victory for the transphobes and other bigots - I did it because so much of the media has chosen to believe the kind and empathetic people are a fiction - they are real and so often unrepresented.
December 13, 2025 at 7:28 AM
Incredibly brave. Imagine the faceless bores the BBC will have making their programmes if they continue down this path.
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If handing someone their arse, was a video clip
December 12, 2025 at 8:12 AM
If handing someone their arse, was a video clip
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I do not like ChatGPT,
Not when it’s paid, nor when it’s free.
I will not use it for a thing,
Especially not for referencing.
It cannot help me with email,
It’s law advice can lead to jail.
It cannot bring back my late Nan,
I do not like it, Sam-Alt-Man.
Not when it’s paid, nor when it’s free.
I will not use it for a thing,
Especially not for referencing.
It cannot help me with email,
It’s law advice can lead to jail.
It cannot bring back my late Nan,
I do not like it, Sam-Alt-Man.
December 10, 2025 at 9:39 PM
I do not like ChatGPT,
Not when it’s paid, nor when it’s free.
I will not use it for a thing,
Especially not for referencing.
It cannot help me with email,
It’s law advice can lead to jail.
It cannot bring back my late Nan,
I do not like it, Sam-Alt-Man.
Not when it’s paid, nor when it’s free.
I will not use it for a thing,
Especially not for referencing.
It cannot help me with email,
It’s law advice can lead to jail.
It cannot bring back my late Nan,
I do not like it, Sam-Alt-Man.
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Getting barred from the USA for making tea and coffee strong enough to actually taste.
Getting barred from the USA for speaking, spelling and writing English well.
Getting barred from the USA because I insisted on calling it The Spar Mangled Banana.
December 11, 2025 at 2:30 PM
Getting barred from the USA for making tea and coffee strong enough to actually taste.
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Sharron Davies has never done anything for women’s rights. She is, however, a racist and transphobic conspiracist
December 10, 2025 at 5:46 PM
Sharron Davies has never done anything for women’s rights. She is, however, a racist and transphobic conspiracist
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"In its 10 years of existence, [press 'regulator' IPSO] has launched no standards investigations and fined no one."
open.substack.com/pub/alanrusb...
open.substack.com/pub/alanrusb...
A crisis at the Jewish Chronicle shows the toothlessness of the press watchdog
The country’s longest-standing Jewish newspaper ran fabricated stories that have prompted a widespread inquiry in Israel. But at home, the press regulator has show little interest in holding the title
open.substack.com
December 11, 2025 at 8:55 AM
"In its 10 years of existence, [press 'regulator' IPSO] has launched no standards investigations and fined no one."
open.substack.com/pub/alanrusb...
open.substack.com/pub/alanrusb...
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Anyone who’s ever actually spoken to a single asylum seeker about their experiences in any country in Europe simply could not honestly conclude that what would improve things would be to further reduce their human rights protections.
It’s vile scapegoating unworthy of us & it needs to end #r4today
It’s vile scapegoating unworthy of us & it needs to end #r4today
December 10, 2025 at 7:35 AM
Anyone who’s ever actually spoken to a single asylum seeker about their experiences in any country in Europe simply could not honestly conclude that what would improve things would be to further reduce their human rights protections.
It’s vile scapegoating unworthy of us & it needs to end #r4today
It’s vile scapegoating unworthy of us & it needs to end #r4today
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"If growth was actually your priority, you would not be doing this."
(Me, stating the obvious)
www.ft.com/content/2b60...
(Me, stating the obvious)
www.ft.com/content/2b60...
Tighter visa rules will cost UK up to £10.8bn
Home Office assessment shows impact of latest changes to immigration regime over next five years
www.ft.com
December 9, 2025 at 5:49 PM
"If growth was actually your priority, you would not be doing this."
(Me, stating the obvious)
www.ft.com/content/2b60...
(Me, stating the obvious)
www.ft.com/content/2b60...
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The court ruled that:
She sent racist messages to colleagues.
She lied in her evidence.
She bullied her trans colleague.
Trans women do not present any risk to other women in changing rooms to toilets.
The headlines don't seem to mention those facts.
She sent racist messages to colleagues.
She lied in her evidence.
She bullied her trans colleague.
Trans women do not present any risk to other women in changing rooms to toilets.
The headlines don't seem to mention those facts.
December 9, 2025 at 12:23 AM
The court ruled that:
She sent racist messages to colleagues.
She lied in her evidence.
She bullied her trans colleague.
Trans women do not present any risk to other women in changing rooms to toilets.
The headlines don't seem to mention those facts.
She sent racist messages to colleagues.
She lied in her evidence.
She bullied her trans colleague.
Trans women do not present any risk to other women in changing rooms to toilets.
The headlines don't seem to mention those facts.
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RFK Jr., I know you can't conceive of caring for anyone else, let alone caring for another life more than your own.
Let alone the pain of wanting to care for your child more than you've ever wanted anything in your entire existence—and your body not allowing you to.
In any case, fuck you to hell.
Let alone the pain of wanting to care for your child more than you've ever wanted anything in your entire existence—and your body not allowing you to.
In any case, fuck you to hell.
RFK Jr: "All of the ingenuity of corporate America has not produced an infant formula that is superior in nutrition and all the qualities that we want to the infant formula that God made, which is the infant formula in a mother's breast."
December 9, 2025 at 6:07 AM
RFK Jr., I know you can't conceive of caring for anyone else, let alone caring for another life more than your own.
Let alone the pain of wanting to care for your child more than you've ever wanted anything in your entire existence—and your body not allowing you to.
In any case, fuck you to hell.
Let alone the pain of wanting to care for your child more than you've ever wanted anything in your entire existence—and your body not allowing you to.
In any case, fuck you to hell.
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So love wobbegongs. Everything is good about the wobbegong. Its name. Its flattened Oscar the Grouch face. Its frondy bits. Its lazy life as a hungry rug. And it’s a shark. Outstanding animal 10/10
The Tasselled Wobbegong is a master of disguise that can eat a fish almost as big as itself in one gulp. It's classified as a shark, but when it lays on the sea floor it looks like a harmless rug if you manage to see it. But with powerful jaws and sharp teeth they are no fish to mess with.
December 8, 2025 at 9:49 AM
So love wobbegongs. Everything is good about the wobbegong. Its name. Its flattened Oscar the Grouch face. Its frondy bits. Its lazy life as a hungry rug. And it’s a shark. Outstanding animal 10/10
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Farage won’t apologise to the victims of his racism and antisemitism.
From that, we can conclude one thing.
He has not changed.
From that, we can conclude one thing.
He has not changed.
December 6, 2025 at 9:35 AM
Farage won’t apologise to the victims of his racism and antisemitism.
From that, we can conclude one thing.
He has not changed.
From that, we can conclude one thing.
He has not changed.
Revolting bigot. Labour can no longer pretend the EHRC is an organisation of any credibility.
Kishwer Falkner in The Times talking about the rights of "biological people". As compared to trans people, who are, of course, non-biological.
December 7, 2025 at 9:38 AM
Revolting bigot. Labour can no longer pretend the EHRC is an organisation of any credibility.
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Very well said and done Emily Thornberry!
Couldn't agree more with her with what she says in this video!
Couldn't agree more with her with what she says in this video!
December 6, 2025 at 7:24 PM
Very well said and done Emily Thornberry!
Couldn't agree more with her with what she says in this video!
Couldn't agree more with her with what she says in this video!
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"I should just point out that this will be the 4th appearance since September for unelected gobshite Zia Yusuf"
December 4, 2025 at 9:32 PM
"I should just point out that this will be the 4th appearance since September for unelected gobshite Zia Yusuf"
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A supposedly grassroots anti-migrant movement led by 'ordinary' women, which is backed by Reform and Conservative politicians and is regularly invited onto news channels to promote their views, is funded by a far-right group and has platformed a Neo-Nazi activist
bylinetimes.com/2025/12/05/t...
bylinetimes.com/2025/12/05/t...
The 'Pink Ladies' Laundering Anti-Migrant Views Into the Mainstream
An anti-migrant movement backed by Reform and Conservative politicians and regularly invited onto news channels is funded by a far-right group and has platformed a Neo-Nazi activist
bylinetimes.com
December 5, 2025 at 10:44 AM
A supposedly grassroots anti-migrant movement led by 'ordinary' women, which is backed by Reform and Conservative politicians and is regularly invited onto news channels to promote their views, is funded by a far-right group and has platformed a Neo-Nazi activist
bylinetimes.com/2025/12/05/t...
bylinetimes.com/2025/12/05/t...