Nat Clarke
@natclarke.bsky.social
Assistant Prof @univmiami.bsky.social. Cellular and Developmental Biology / Evo-Devo / Animal Multicellularity / Cell adhesion. Lover of weird invertebrates. Learn more: clarkelab.com
Pinned
Nat Clarke
@natclarke.bsky.social
· Oct 8
🚨 My lab is hiring at all levels!
Interested in animal origins & evolutionary cell biology?
I'm recruiting a postdoc, PhD students & a research assistant to study the molecular evolution of cell adhesion using marine invertebrates + comparative genomics.
🔗: clarkelab.com/join/
Please repost!
Interested in animal origins & evolutionary cell biology?
I'm recruiting a postdoc, PhD students & a research assistant to study the molecular evolution of cell adhesion using marine invertebrates + comparative genomics.
🔗: clarkelab.com/join/
Please repost!
Reposted by Nat Clarke
NEW pub in @science.org 🥳
Is it sponges (panels A & B) or comb jellies (C & D) that root the animal tree of life?
For over 15 years, #phylogenomic studies have been divided.
We provide new evidence suggesting that...
🔗: www.science.org/doi/10.1126/...
Is it sponges (panels A & B) or comb jellies (C & D) that root the animal tree of life?
For over 15 years, #phylogenomic studies have been divided.
We provide new evidence suggesting that...
🔗: www.science.org/doi/10.1126/...
November 13, 2025 at 8:34 PM
NEW pub in @science.org 🥳
Is it sponges (panels A & B) or comb jellies (C & D) that root the animal tree of life?
For over 15 years, #phylogenomic studies have been divided.
We provide new evidence suggesting that...
🔗: www.science.org/doi/10.1126/...
Is it sponges (panels A & B) or comb jellies (C & D) that root the animal tree of life?
For over 15 years, #phylogenomic studies have been divided.
We provide new evidence suggesting that...
🔗: www.science.org/doi/10.1126/...
Reposted by Nat Clarke
The Lariviere lab at UMiami is recruiting PhD students! Incoming students will join us in studying host-microbe interactions in the honey bee gut, using molecular and genetic approaches. Please see the attached flyer for more details.
#Symbiosis #SymbioSky #MicroSky #PhDOpportunity #AcademicJobs
#Symbiosis #SymbioSky #MicroSky #PhDOpportunity #AcademicJobs
November 13, 2025 at 3:14 PM
The Lariviere lab at UMiami is recruiting PhD students! Incoming students will join us in studying host-microbe interactions in the honey bee gut, using molecular and genetic approaches. Please see the attached flyer for more details.
#Symbiosis #SymbioSky #MicroSky #PhDOpportunity #AcademicJobs
#Symbiosis #SymbioSky #MicroSky #PhDOpportunity #AcademicJobs
Reposted by Nat Clarke
My book 'The Tree of Life' is published in the USA and Canada today.
Available as book, on kindle and as audio.
I would be really grateful for reposts.
www.amazon.com/Tree-Life-So...
www.amazon.ca/Tree-Life-So...
Available as book, on kindle and as audio.
I would be really grateful for reposts.
www.amazon.com/Tree-Life-So...
www.amazon.ca/Tree-Life-So...
November 11, 2025 at 12:01 PM
My book 'The Tree of Life' is published in the USA and Canada today.
Available as book, on kindle and as audio.
I would be really grateful for reposts.
www.amazon.com/Tree-Life-So...
www.amazon.ca/Tree-Life-So...
Available as book, on kindle and as audio.
I would be really grateful for reposts.
www.amazon.com/Tree-Life-So...
www.amazon.ca/Tree-Life-So...
Reposted by Nat Clarke
"Saving Science by the Sea" – a piece on the importance of marine laboratories in advancing biomedical science, including the beginning of the Meselson-Stahl collaboration that ultimately elucidated the process of DNA replication:
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Saving science by the sea
As funding for science tightens across the United States, attention has turned to pressures faced by universities and biomedical research institutions. An often overlooked part of the nation’s science...
www.science.org
November 10, 2025 at 1:17 AM
"Saving Science by the Sea" – a piece on the importance of marine laboratories in advancing biomedical science, including the beginning of the Meselson-Stahl collaboration that ultimately elucidated the process of DNA replication:
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Nat Clarke
We’re hiring! 🚨
Assistant Professor (TT) in Theoretical or Computational Biological Physics @univmiami.bsky.social 😀
Come build the future of interdisciplinary biophysics with us!
Apply by Dec 15 → tinyurl.com/5n9bk836
#Biophysics #PhysicsJobs #AcademicJobs #UMiami
Assistant Professor (TT) in Theoretical or Computational Biological Physics @univmiami.bsky.social 😀
Come build the future of interdisciplinary biophysics with us!
Apply by Dec 15 → tinyurl.com/5n9bk836
#Biophysics #PhysicsJobs #AcademicJobs #UMiami
November 8, 2025 at 5:54 PM
We’re hiring! 🚨
Assistant Professor (TT) in Theoretical or Computational Biological Physics @univmiami.bsky.social 😀
Come build the future of interdisciplinary biophysics with us!
Apply by Dec 15 → tinyurl.com/5n9bk836
#Biophysics #PhysicsJobs #AcademicJobs #UMiami
Assistant Professor (TT) in Theoretical or Computational Biological Physics @univmiami.bsky.social 😀
Come build the future of interdisciplinary biophysics with us!
Apply by Dec 15 → tinyurl.com/5n9bk836
#Biophysics #PhysicsJobs #AcademicJobs #UMiami
Reposted by Nat Clarke
Pleased to share our latest paper led by @tomlewin.bsky.social, now out in @currentbiology.bsky.social! We present the first chromosome-level genome of a phoronid and show that shared chromosomal fusions unite phoronids and bryozoans as sister groups.
www.cell.com/current-biol...
www.cell.com/current-biol...
November 7, 2025 at 4:21 PM
Pleased to share our latest paper led by @tomlewin.bsky.social, now out in @currentbiology.bsky.social! We present the first chromosome-level genome of a phoronid and show that shared chromosomal fusions unite phoronids and bryozoans as sister groups.
www.cell.com/current-biol...
www.cell.com/current-biol...
Reposted by Nat Clarke
I am beyond excited to share that my postdoc project @szndohrn.bsky.social and the @arnonelab.bsky.social is now available in #ScienceAdvances @science.org. www.science.org/doi/10.1126/...
November 5, 2025 at 7:02 PM
I am beyond excited to share that my postdoc project @szndohrn.bsky.social and the @arnonelab.bsky.social is now available in #ScienceAdvances @science.org. www.science.org/doi/10.1126/...
Reposted by Nat Clarke
Major cell type differences between larval and adult hemichordate body plans https://www.biorxiv.org/content/10.1101/2025.10.31.685866v1
November 3, 2025 at 7:31 PM
Major cell type differences between larval and adult hemichordate body plans https://www.biorxiv.org/content/10.1101/2025.10.31.685866v1
Reposted by Nat Clarke
🚨 We're hiring! 🚨 Our lab at the University of Málaga, Spain🇪🇸 is looking for a bioinformatician researcher for a postdoc position (1+1 years). Check the ad, and if you're interested, get in touch!
📅 Starting date early 2026, with some flexibility.
🙏Please, RT!
📅 Starting date early 2026, with some flexibility.
🙏Please, RT!
October 30, 2025 at 5:50 PM
🚨 We're hiring! 🚨 Our lab at the University of Málaga, Spain🇪🇸 is looking for a bioinformatician researcher for a postdoc position (1+1 years). Check the ad, and if you're interested, get in touch!
📅 Starting date early 2026, with some flexibility.
🙏Please, RT!
📅 Starting date early 2026, with some flexibility.
🙏Please, RT!
Reposted by Nat Clarke
🚨Our collaboration with @centriolelab.bsky.social & @gautamdey.bsky.social is out today in @cp-cell.bsky.social
We show that #Expansion #Microscopy is a broad-spectrum modality for Euks, enabling 3D phenotypic maps rooted to phylogeny.
#ProtistsOnSky #SciComm #SciSky
www.cell.com/cell/fulltex...
We show that #Expansion #Microscopy is a broad-spectrum modality for Euks, enabling 3D phenotypic maps rooted to phylogeny.
#ProtistsOnSky #SciComm #SciSky
www.cell.com/cell/fulltex...
October 31, 2025 at 2:42 PM
🚨Our collaboration with @centriolelab.bsky.social & @gautamdey.bsky.social is out today in @cp-cell.bsky.social
We show that #Expansion #Microscopy is a broad-spectrum modality for Euks, enabling 3D phenotypic maps rooted to phylogeny.
#ProtistsOnSky #SciComm #SciSky
www.cell.com/cell/fulltex...
We show that #Expansion #Microscopy is a broad-spectrum modality for Euks, enabling 3D phenotypic maps rooted to phylogeny.
#ProtistsOnSky #SciComm #SciSky
www.cell.com/cell/fulltex...
Reposted by Nat Clarke
Very happy to see our paper published online natcomms.nature.com. Thank you to @wellcometrust.bsky.social for funding this work during my time with @robklose.bsky.social and David Booth! Thanks also to collaborators @garcialabms.bsky.social @alexdemendoza.bsky.social and the other authors!
Chromatin profiling identifies putative dual roles for H3K27me3 in regulating cell type-specific genes and transposable elements in choanoflagellates
Nature Communications - Here, the authors investigate chromatin-based gene regulation in the closest relative of animal, choanoflagellates. They uncover a putative dual role for the histone...
rdcu.be
October 29, 2025 at 1:40 PM
Very happy to see our paper published online natcomms.nature.com. Thank you to @wellcometrust.bsky.social for funding this work during my time with @robklose.bsky.social and David Booth! Thanks also to collaborators @garcialabms.bsky.social @alexdemendoza.bsky.social and the other authors!
Reposted by Nat Clarke
How can we see the cells that make up a living organism? Membrane-localising tags can drive fluorescent proteins to the cell's outer membrane, making their outlines visible. But the tags don't work well in all organisms. How do you find one for your species of interest? 🧵
Check our latest preprint
Check our latest preprint
A toolkit for testing membrane-localising tags across species
Transgenic markers and tools have revolutionised how we study cells and developing organisms. Some of the elements needed to construct those tools are universally applicable (e.g. fluorescent proteins...
www.biorxiv.org
October 23, 2025 at 8:16 AM
How can we see the cells that make up a living organism? Membrane-localising tags can drive fluorescent proteins to the cell's outer membrane, making their outlines visible. But the tags don't work well in all organisms. How do you find one for your species of interest? 🧵
Check our latest preprint
Check our latest preprint
Reposted by Nat Clarke
Two tenure-track faculty positions open in our department:
1) Microbial Ecology and Evolution careers.rpi.edu/en-us/job/49...
2) Cellular Neuroscience careers.rpi.edu/en-us/job/49...
Join our collaborative, interdisciplinary community, which has proved to be a fantastic place to start a lab!
1) Microbial Ecology and Evolution careers.rpi.edu/en-us/job/49...
2) Cellular Neuroscience careers.rpi.edu/en-us/job/49...
Join our collaborative, interdisciplinary community, which has proved to be a fantastic place to start a lab!
Details - Assistant Professor, Microbial Ecology - RPI Jobs
careers.rpi.edu
October 22, 2025 at 4:46 PM
Two tenure-track faculty positions open in our department:
1) Microbial Ecology and Evolution careers.rpi.edu/en-us/job/49...
2) Cellular Neuroscience careers.rpi.edu/en-us/job/49...
Join our collaborative, interdisciplinary community, which has proved to be a fantastic place to start a lab!
1) Microbial Ecology and Evolution careers.rpi.edu/en-us/job/49...
2) Cellular Neuroscience careers.rpi.edu/en-us/job/49...
Join our collaborative, interdisciplinary community, which has proved to be a fantastic place to start a lab!
Reposted by Nat Clarke
📣 Fully-funded PhD opportunity in my Lab @bristolbiosci.bsky.social @bristoluni.bsky.social
🔬We will explore how coral larvae sense their environment and guide settlement.
Check out the details! 👇
www.findaphd.com/phds/project...
#Coral #SensoryEcology #PhD #MarineScience
🔬We will explore how coral larvae sense their environment and guide settlement.
Check out the details! 👇
www.findaphd.com/phds/project...
#Coral #SensoryEcology #PhD #MarineScience
October 21, 2025 at 6:57 PM
📣 Fully-funded PhD opportunity in my Lab @bristolbiosci.bsky.social @bristoluni.bsky.social
🔬We will explore how coral larvae sense their environment and guide settlement.
Check out the details! 👇
www.findaphd.com/phds/project...
#Coral #SensoryEcology #PhD #MarineScience
🔬We will explore how coral larvae sense their environment and guide settlement.
Check out the details! 👇
www.findaphd.com/phds/project...
#Coral #SensoryEcology #PhD #MarineScience
Reposted by Nat Clarke
Sea cucumbers are beautiful! 🥒
This image shows the skeleton of a baby sea cucumber. Very happy that it got awarded by #NikonSmallWorld 😊
👇 Check the preprint by @PranavVyas and @prakashlab.bsky.social if you want to learn more about skeleton development in these animals:
shorturl.at/J3g1h
This image shows the skeleton of a baby sea cucumber. Very happy that it got awarded by #NikonSmallWorld 😊
👇 Check the preprint by @PranavVyas and @prakashlab.bsky.social if you want to learn more about skeleton development in these animals:
shorturl.at/J3g1h
October 16, 2025 at 3:29 PM
Sea cucumbers are beautiful! 🥒
This image shows the skeleton of a baby sea cucumber. Very happy that it got awarded by #NikonSmallWorld 😊
👇 Check the preprint by @PranavVyas and @prakashlab.bsky.social if you want to learn more about skeleton development in these animals:
shorturl.at/J3g1h
This image shows the skeleton of a baby sea cucumber. Very happy that it got awarded by #NikonSmallWorld 😊
👇 Check the preprint by @PranavVyas and @prakashlab.bsky.social if you want to learn more about skeleton development in these animals:
shorturl.at/J3g1h
Reposted by Nat Clarke
We are happy to share our latest work in @nature.com . We study the genomic and cellular basis of facultative symbiosis in Oculina patagonica - a Mediterranean coral remarkable for its ability to survive long periods without algal symbionts. Led by Shani Levy and @xgrau.bsky.social
rdcu.be/eLbaZ
rdcu.be/eLbaZ
October 15, 2025 at 7:58 PM
We are happy to share our latest work in @nature.com . We study the genomic and cellular basis of facultative symbiosis in Oculina patagonica - a Mediterranean coral remarkable for its ability to survive long periods without algal symbionts. Led by Shani Levy and @xgrau.bsky.social
rdcu.be/eLbaZ
rdcu.be/eLbaZ
Reposted by Nat Clarke
We have PhD and Postdoc positions open in our group. Join us in Lausanne to explore how cells pull off extreme shape changes and how cilia drive biological flows.
You can find more details on the projects available and how to apply in our website:
www.epfl.ch/labs/lpl/joi...
You can find more details on the projects available and how to apply in our website:
www.epfl.ch/labs/lpl/joi...
Join us !
We are looking for creative and motivated scientists at to join the group. We are recruiting candidates from various scientific backgrounds including, but not limited to: biophysics, physics, biochemi...
www.epfl.ch
October 15, 2025 at 11:20 AM
We have PhD and Postdoc positions open in our group. Join us in Lausanne to explore how cells pull off extreme shape changes and how cilia drive biological flows.
You can find more details on the projects available and how to apply in our website:
www.epfl.ch/labs/lpl/joi...
You can find more details on the projects available and how to apply in our website:
www.epfl.ch/labs/lpl/joi...
Reposted by Nat Clarke
We hire!
The CytoMorpho Lab is looking for an engineer with a background in cell and molecular biology to join our team in Paris. This is a 18-month contract position, but we're open to exploring long-term opportunities.
More details here:
cytomorpholab.com/index.php/jo...
The CytoMorpho Lab is looking for an engineer with a background in cell and molecular biology to join our team in Paris. This is a 18-month contract position, but we're open to exploring long-term opportunities.
More details here:
cytomorpholab.com/index.php/jo...
October 14, 2025 at 1:50 PM
We hire!
The CytoMorpho Lab is looking for an engineer with a background in cell and molecular biology to join our team in Paris. This is a 18-month contract position, but we're open to exploring long-term opportunities.
More details here:
cytomorpholab.com/index.php/jo...
The CytoMorpho Lab is looking for an engineer with a background in cell and molecular biology to join our team in Paris. This is a 18-month contract position, but we're open to exploring long-term opportunities.
More details here:
cytomorpholab.com/index.php/jo...
Reposted by Nat Clarke
I'm very excited to announce that UNC Biology has 6 faculty positions open this year! The first is for an Asst Professor who studies organismal resilience using an integrative approach 1/n
unc.peopleadmin.com/postings/307...
unc.peopleadmin.com/postings/307...
October 12, 2025 at 2:20 PM
I'm very excited to announce that UNC Biology has 6 faculty positions open this year! The first is for an Asst Professor who studies organismal resilience using an integrative approach 1/n
unc.peopleadmin.com/postings/307...
unc.peopleadmin.com/postings/307...
Reposted by Nat Clarke
Many sea stars begin life as young fairy-like creature (called a brachiolaria) that float through the open ocean. Eventually, a small star forms within them (here in yellow). The fairy-like brachiolaria sinks under the star’s weight, and the star pops out!
🎥@the_story_of_a_biologist (on Insta)
🎥@the_story_of_a_biologist (on Insta)
October 9, 2025 at 4:24 AM
Many sea stars begin life as young fairy-like creature (called a brachiolaria) that float through the open ocean. Eventually, a small star forms within them (here in yellow). The fairy-like brachiolaria sinks under the star’s weight, and the star pops out!
🎥@the_story_of_a_biologist (on Insta)
🎥@the_story_of_a_biologist (on Insta)
🚨 My lab is hiring at all levels!
Interested in animal origins & evolutionary cell biology?
I'm recruiting a postdoc, PhD students & a research assistant to study the molecular evolution of cell adhesion using marine invertebrates + comparative genomics.
🔗: clarkelab.com/join/
Please repost!
Interested in animal origins & evolutionary cell biology?
I'm recruiting a postdoc, PhD students & a research assistant to study the molecular evolution of cell adhesion using marine invertebrates + comparative genomics.
🔗: clarkelab.com/join/
Please repost!
October 8, 2025 at 5:49 PM
🚨 My lab is hiring at all levels!
Interested in animal origins & evolutionary cell biology?
I'm recruiting a postdoc, PhD students & a research assistant to study the molecular evolution of cell adhesion using marine invertebrates + comparative genomics.
🔗: clarkelab.com/join/
Please repost!
Interested in animal origins & evolutionary cell biology?
I'm recruiting a postdoc, PhD students & a research assistant to study the molecular evolution of cell adhesion using marine invertebrates + comparative genomics.
🔗: clarkelab.com/join/
Please repost!
Reposted by Nat Clarke
Are you interested in how multicellular vertices resolve in epithelia?
Checkout our recent bioRxiv preprint www.biorxiv.org/content/10.1...
(Scroll down to see some cool videos)
Checkout our recent bioRxiv preprint www.biorxiv.org/content/10.1...
(Scroll down to see some cool videos)
PAK4 promotes vertex remodeling to maintain epithelial integrity and barrier function
Cell-cell junctions are essential for epithelial integrity and barrier function, but the mechanisms regulating their remodeling remain unclear. Here, we investigated the role of the junctional kinase ...
www.biorxiv.org
October 5, 2025 at 3:06 PM
Are you interested in how multicellular vertices resolve in epithelia?
Checkout our recent bioRxiv preprint www.biorxiv.org/content/10.1...
(Scroll down to see some cool videos)
Checkout our recent bioRxiv preprint www.biorxiv.org/content/10.1...
(Scroll down to see some cool videos)
Reposted by Nat Clarke
Latest from ours: www.cell.com/cell-reports...
This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵
This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵
October 5, 2025 at 10:35 AM
Latest from ours: www.cell.com/cell-reports...
This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵
This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵
Reposted by Nat Clarke
We knew that cnidarians have stunning regenerative capacities. But the molecular and cellular mechanisms underlying the self-organization of gastruloids of Nematostella surprised us. A story of cell sorting and Notch signaling. Please check out the work of Sanjay's PhD work: doi.org/10.1101/2025...
September 11, 2025 at 4:16 PM
We knew that cnidarians have stunning regenerative capacities. But the molecular and cellular mechanisms underlying the self-organization of gastruloids of Nematostella surprised us. A story of cell sorting and Notch signaling. Please check out the work of Sanjay's PhD work: doi.org/10.1101/2025...
Reposted by Nat Clarke
I am very happy to announce that the Echinox Lab will open in the BIOM unit at @obs-banyuls.fr in January 2026!! 🥳
We will use several echinoderm species to study animal body plan evolution.
🔽 Check our brand new lab website if you want to learn more about our future research
www.echinox.org
We will use several echinoderm species to study animal body plan evolution.
🔽 Check our brand new lab website if you want to learn more about our future research
www.echinox.org
September 10, 2025 at 8:48 PM
I am very happy to announce that the Echinox Lab will open in the BIOM unit at @obs-banyuls.fr in January 2026!! 🥳
We will use several echinoderm species to study animal body plan evolution.
🔽 Check our brand new lab website if you want to learn more about our future research
www.echinox.org
We will use several echinoderm species to study animal body plan evolution.
🔽 Check our brand new lab website if you want to learn more about our future research
www.echinox.org