Marco Trizzino
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marcotrizzino.bsky.social
Marco Trizzino
@marcotrizzino.bsky.social
2.8K followers 1.1K following 210 posts
Associate Professor of Developmental and Evolutionary Genomics at Imperial College London, Department of Life Sciences. Spent a decade in Philly, #FlyEaglesFly
https://marcotrizzino.wordpress.com/
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marcotrizzino.bsky.social
Marco Trizzino @marcotrizzino.bsky.social · Sep 22
Our study on the role of LTR5HS and SVAs in regulation of human neural crest migration is now published as peer-reviewed paper on @molsystbiol.org!
Congrats to first author brilliant postdoc Laura Deelen, and all the authors involved! @imperialsci.bsky.social
www.embopress.org/doi/full/10....
marcotrizzino.bsky.social
Now “The Big Beautiful Bill” makes a lot more sense
November 16, 2025 at 9:42 AM
Reposted by Marco Trizzino
orpsf.bsky.social
Thrilled to share our new review in Current Opinion in Genetics & Development on TE driven innovation in gene regulation🤘. I am honored to be part of this with two major TE aficionados @cedricfeschotte.bsky.social and @trono-lab.bsky.social
#TEsky #TEworldwide

authors.elsevier.com/c/1m6MC,LqAZ...
November 15, 2025 at 5:23 PM
Reposted by Marco Trizzino
crick.ac.uk
This image shows a mass of human stem cells, collectively known as an ‘organoid’.

We stained the neural crest cells of this organoid to better understand diseases related to defects in their development, such as Hirschsprung's disease and Neuroblastoma.

Image credit: @carmenmorenogon.bsky.social
A circle composed of many oval-shaped dots, mostly coloured blue apart from a few pink ones in the bottom left corner.
November 10, 2025 at 9:27 AM
Reposted by Marco Trizzino
bencollins.bsky.social
“I want you to understand what it is like to live in Chicago during this time.”

aphyr.com/posts/397-i-...
I want you to understand what it is like to live in Chicago during this time. Every day my phone buzzes. It is a neighborhood group: four people were kidnapped at the corner drugstore. A friend a mile away sends a Slack message: she was at the scene when masked men assaulted and abducted two people on the street. A plumber working on my pipes is distraught, and I find out that two of his employees were kidnapped that morning. A week later it happens again. An email arrives. Agents with guns have chased a teacher into the school where she works. They did not have a warrant. They dragged her away, ignoring her and her colleagues’ pleas to show proof of her documentation. That evening I stand a few feet from the parents of Rayito de Sol and listen to them describe, with anguish, how good Ms. Diana was to their children. What it is like to have strangers with guns traumatize your kids. For a teacher to hide a three-year-old child for fear they might be killed. How their relatives will no longer leave the house. I hear the pain and fury in their voices, and I wonder who will be next. Understand what it is to pray in Chicago.
November 9, 2025 at 5:26 PM
marcotrizzino.bsky.social
Congratulations @fueyoraquel.bsky.social !!
November 7, 2025 at 1:50 PM
marcotrizzino.bsky.social
The new album by Rosalia is MIND BLOWING.
November 7, 2025 at 1:43 PM
Reposted by Marco Trizzino
christoseland.bsky.social
Please repost - Multiple PhDs available

www.findaphd.com/phds/project...

www.findaphd.com/phds/project...

www.findaphd.com/phds/project...
November 5, 2025 at 9:18 AM
marcotrizzino.bsky.social
I have been living in the UK for several years, and still can't wrap my head around the fact that half the country calls lunch "dinner" and dinner "tea", while the other half of the country calls lunch "lunch" and dinner "dinner" with the exception of school lunches, that are called school dinners
November 5, 2025 at 1:19 PM
Reposted by Marco Trizzino
biologists.bsky.social
One month left for early-career researchers to apply for a funded place at our Workshop 'Novelty, Co-option and Divergence During Gene Network Evolution' organised by James Hombría & Antónia Monteiro Deadline 5 Dec.
biologists.com/workshops/ju...

@isabelalmudi.bsky.social @jlopezrios.bsky.social
Novelty, Co-option and Divergence During Gene Network Evolution
Novelty, Co-option and Divergence During Gene Network Evolution Recent studies on the evolution of novel traits provide a window of opportunity to understand how existing gene-regulatory networks (GRN...
biologists.com
November 5, 2025 at 7:31 AM
Reposted by Marco Trizzino
maxperutzlabs.ac.at
📢 Open Call! The Max Perutz Labs invite applications for a Tenure-Track Professorship in Genome Biology. We are particularly interested in researchers investigating the molecular and biophysical mechanisms underlying genome function and regulation. More details ➡️ tinyurl.com/3t7vvdct
November 5, 2025 at 10:59 AM
Reposted by Marco Trizzino
sj-marzi.bsky.social
@andreaserio.bsky.social and I are recruiting a postdoc to lead an exciting MNDA-funded project using multi-omics to study long axons in motor neurons and how they shape susceptibility to #ALS.

Get in touch for any questions and apply by 2 December:
my.corehr.com/pls/kclrecru...
Stained axons
November 4, 2025 at 5:33 PM
marcotrizzino.bsky.social
Current situation in my household (we have a 6 year old girl)
Golden
November 2, 2025 at 7:57 PM
Reposted by Marco Trizzino
yukihaba.bsky.social
How does life evolve to adapt to modern cities?

Out now in Science, my PhD work with @lindymcbr.bsky.social uncovers the ancient origin of the “London Underground mosquito” – one of the most iconic examples of urban adaptation.

🧵(1/n)
@science.org
www.science.org/doi/10.1126/science.ady4515
Ancient origin of an urban underground mosquito
Understanding how life is adapting to urban environments represents an important challenge in evolutionary biology. In this work, we investigate a widely cited example of urban adaptation, Culex pipie...
www.science.org
October 25, 2025 at 4:46 AM
Reposted by Marco Trizzino
ella-pbn.bsky.social
Check out our new preprint on the evolution of enhancer loss. Turns out there are 50 ways to lose a function. We found four of them.

www.biorxiv.org/content/10.1...
Distinct mechanisms decommission redundant enhancers to facilitate phenotypic evolution
The evolutionary loss of morphological traits is often driven by changes in gene regulation. Many developmental genes are controlled by multiple, redundant enhancers, raising the question of how robus...
www.biorxiv.org
October 28, 2025 at 8:06 PM
Reposted by Marco Trizzino
maxvcg.bsky.social
Spread the word! There is a professor position opening at our University @upcite.bsky.social. There are several possible (great) labs to join, but if you are interested in DNA methylation and epigenetics in mammals, don't hesitate to contact me directly!
ijmonod.bsky.social Institut Jacques Monod @ijmonod.bsky.social · 20d
#JobOffer

💼 Un poste susceptible d’être vacant de Professeur en stabilité des génomes devrait s’ouvrir pour la rentrée 2026 au sein de l’Institut Jacques Monod

➡️ Informations concernant ce poste et la procédure de candidature 🔗 www.ijm.fr/poste-de-pro...
October 28, 2025 at 1:51 PM
Reposted by Marco Trizzino
embo.org
Sign up now for EMBO Workshop "Molecular mechanisms of selfish elements and strategies" in Bern, Switzerland, 8–11 February 2026.

Abstract submission/Registration by: 15 December 2025/15 January 2026

https://meetings.embo.org/event/26-selfish-elements
#EMBOselfishElements #GeneSky #EMBOevents 🧪
Molecular mechanisms of selfish elements and strategies
Certain genes, chromosomes, organelles, or entire sets of chromosomes can bias their transmission to the next generation, propagating themselves at the expense of the rest of the genome. Referred to …
meetings.embo.org
October 29, 2025 at 7:20 AM
Reposted by Marco Trizzino
embojournal.org
TET knockout cells transit between pluripotent states and exhibit precocious germline entry
Ian Chambers and collaborators
www.embopress.org/doi/full/10....
October 27, 2025 at 12:25 PM
Reposted by Marco Trizzino
sedonamurphy.bsky.social
Here, we show that the unique regulatory landscape of ecDNA enables an ancient LINE to resurrect and act as an enhancer of Myc. This was so fun with @katerinakraft.bsky.social and @mattjones.bsky.social and others. www.nature.com/articles/s41...
Enhancer activation from transposable elements in extrachromosomal DNA - Nature Cell Biology
Kraft, Murphy, Jones et al. identify extrachromosomal DNA (ecDNA)-interacting elements (EIEs) enriched for transposable elements within ecDNA in colorectal cancer cells. They show that EIE 14 integrat...
www.nature.com
October 21, 2025 at 9:43 AM
Reposted by Marco Trizzino
robklose.bsky.social
We are recuiting two new Associate Professors here in Oxford Biochemistry. Come join us! Reach out to me if you have any questions. Please repost! tinyurl.com/mr3m7bd3
October 17, 2025 at 2:56 PM
Reposted by Marco Trizzino
blanka-majchrzycka.bsky.social
Out now! 🎉 Check the thread & preprint to see why we think E–P specificity is real in mammals — and, well, a few other interesting things popped up too 👀
Huge thanks to @danielibrahim.bsky.social, @arnaudkr.bsky.social & @stemundi.bsky.social and fantastic people in their labs — what a journey! 🧪🔬
October 17, 2025 at 5:50 AM
Reposted by Marco Trizzino
kaessmannlab.bsky.social
Did transposable elements shape brain evolution — and if so, which ones, and in which cell states and lineages? Led by @tyamadat.bsky.social, we explored this question in cerebellum development using sequence-based deep learning models!
www.biorxiv.org/content/10.1...
October 16, 2025 at 10:01 PM
Reposted by Marco Trizzino
electionmaps.uk
Following the announcement of YourParty, support for 'Others' in opinion polls increased from 3.7% to 6.0%. It has since dropped back to 3.7%, with the Greens seemingly gaining, reaching a peak of 10.7%.

electionmaps.uk/polling/vi
October 15, 2025 at 10:21 AM
Reposted by Marco Trizzino
raduzabet.bsky.social
DNA methylation is one of the most studied epigenetic modification associated with regulation of gene expression. Bisulfite-converted genomic DNA sequencing has been the current gold standard in the field for building genome-wide DNAm maps at base pair resolution.
October 14, 2025 at 8:21 AM
marcotrizzino.bsky.social
Always the same speakers…

www.keystonesymposia.org/conferences/...
Epigenetics and Gene Regulation in Health and Disease: Linking Basic Mechanisms with Therapeutic Opportunities | Keystone Symposia
Join us at the Keystone Symposia on Epigenetics and Gene Regulation in Health and Disease: Linking Basic Mechanisms with Therapeutic Opportunities, March 2026, in Geneva, with field leaders!
www.keystonesymposia.org
October 11, 2025 at 6:06 PM
marcotrizzino.bsky.social
Our Department @imperialcollegeldn.bsky.social just received 546 applications for 3 Assistant/Associate Professor positions. Curious to see how many of these are American scientists trying to relocate
October 11, 2025 at 6:05 PM