Lee Zamparo
@lzamparo.bsky.social
Interested in ML, comp bio, immunology, and just about anything one hop away from either.
Reposted by Lee Zamparo
we released Olmo 3! lot of exciting stuff but wanna focus on:
🐟Olmo 3 32B Base, the best fully-open base model to-date, near Qwen 2.5 & Gemma 3 on diverse evals
🐠Olmo 3 32B Think, first fully-open reasoning model approaching Qwen 3 levels
🐡12 training datasets corresp to different staged training
🐟Olmo 3 32B Base, the best fully-open base model to-date, near Qwen 2.5 & Gemma 3 on diverse evals
🐠Olmo 3 32B Think, first fully-open reasoning model approaching Qwen 3 levels
🐡12 training datasets corresp to different staged training
November 20, 2025 at 6:20 PM
we released Olmo 3! lot of exciting stuff but wanna focus on:
🐟Olmo 3 32B Base, the best fully-open base model to-date, near Qwen 2.5 & Gemma 3 on diverse evals
🐠Olmo 3 32B Think, first fully-open reasoning model approaching Qwen 3 levels
🐡12 training datasets corresp to different staged training
🐟Olmo 3 32B Base, the best fully-open base model to-date, near Qwen 2.5 & Gemma 3 on diverse evals
🐠Olmo 3 32B Think, first fully-open reasoning model approaching Qwen 3 levels
🐡12 training datasets corresp to different staged training
Reposted by Lee Zamparo
In a new phase 3 trial, people randomly assigned to receive a flu shot made with modified mRNA were 34.5% less likely to be diagnosed with an influenza-like illness than people given a standard flu shot made with inactivated virus.
We need to stop the anti-science attacks against mRNA vaccines!
We need to stop the anti-science attacks against mRNA vaccines!
November 20, 2025 at 1:03 AM
In a new phase 3 trial, people randomly assigned to receive a flu shot made with modified mRNA were 34.5% less likely to be diagnosed with an influenza-like illness than people given a standard flu shot made with inactivated virus.
We need to stop the anti-science attacks against mRNA vaccines!
We need to stop the anti-science attacks against mRNA vaccines!
Reposted by Lee Zamparo
Come do a PhD internship with me!
You have until Dec 1 to apply to the bioml PhD research internship!
This is where you apply to work with me,
@alexijie.bsky.social @avapamini.bsky.social @lcrawford.bsky.social or Kristen Severson!
(new) link and some instructions below
apply.careers.microsoft.com/careers/job/...
This is where you apply to work with me,
@alexijie.bsky.social @avapamini.bsky.social @lcrawford.bsky.social or Kristen Severson!
(new) link and some instructions below
apply.careers.microsoft.com/careers/job/...
Research Intern - Machine Learning for Biology and Healthcare | Microsoft Careers
Research Interns put inquiry and theory into practice. Alongside fellow doctoral candidates and some of the world's best researchers, Research Interns learn, collaborate, and network for life. Researc...
apply.careers.microsoft.com
November 20, 2025 at 3:31 PM
Come do a PhD internship with me!
Reposted by Lee Zamparo
My first @umasschan.bsky.social/@impvienna.bsky.social affiliated paper is up!
tomtom-lite is a re-implementation of tomtom targeting the ML age of genomics. Fast annotations ("what is this motif?") and simple large-scale discovery of motifs.
Check it out!
academic.oup.com/bioinformati...
tomtom-lite is a re-implementation of tomtom targeting the ML age of genomics. Fast annotations ("what is this motif?") and simple large-scale discovery of motifs.
Check it out!
academic.oup.com/bioinformati...
November 20, 2025 at 2:02 PM
My first @umasschan.bsky.social/@impvienna.bsky.social affiliated paper is up!
tomtom-lite is a re-implementation of tomtom targeting the ML age of genomics. Fast annotations ("what is this motif?") and simple large-scale discovery of motifs.
Check it out!
academic.oup.com/bioinformati...
tomtom-lite is a re-implementation of tomtom targeting the ML age of genomics. Fast annotations ("what is this motif?") and simple large-scale discovery of motifs.
Check it out!
academic.oup.com/bioinformati...
Reposted by Lee Zamparo
Creating a caricature of your critics in order to dodge responsibility for the negative consequences of your votes is the real immaturity here. If you don't want to be held accountable for the way your votes affect Toronto, maybe councillor isn't the right job for you.
November 18, 2025 at 1:06 PM
Creating a caricature of your critics in order to dodge responsibility for the negative consequences of your votes is the real immaturity here. If you don't want to be held accountable for the way your votes affect Toronto, maybe councillor isn't the right job for you.
This is as close as I want to get to the trashful profile in the Times. This take is true, not only supported by how many of them have shamefully acquiesced to Trump this past year, but also by who is corruptly profiting in plain sight from it. Much shame to go around.
the story is about how the American elite is rotten to its very marrow, to the extent that half of it was plotting and scheming about how to use Trump to advance their own venal interests before he even won
November 14, 2025 at 8:07 PM
This is as close as I want to get to the trashful profile in the Times. This take is true, not only supported by how many of them have shamefully acquiesced to Trump this past year, but also by who is corruptly profiting in plain sight from it. Much shame to go around.
the aws cli is utter trash, a total disgrace to the fine lineage of shell tools.
November 12, 2025 at 9:59 PM
the aws cli is utter trash, a total disgrace to the fine lineage of shell tools.
Reposted by Lee Zamparo
you should quit social media if you can.
if you can't, you should use apps that give you and old-school reverse chronological feed of posts from people you follow. yes, like bluesky.
www.gelliottmorris.com/p/you-should...
if you can't, you should use apps that give you and old-school reverse chronological feed of posts from people you follow. yes, like bluesky.
www.gelliottmorris.com/p/you-should...
You should quit social media for good
Platforms optimized for engagement warp our politics, erode attention, and harm our wellbeing. Here’s how I minimize time on the (anti‑)social web.
www.gelliottmorris.com
November 12, 2025 at 1:01 PM
you should quit social media if you can.
if you can't, you should use apps that give you and old-school reverse chronological feed of posts from people you follow. yes, like bluesky.
www.gelliottmorris.com/p/you-should...
if you can't, you should use apps that give you and old-school reverse chronological feed of posts from people you follow. yes, like bluesky.
www.gelliottmorris.com/p/you-should...
Reposted by Lee Zamparo
Great piece by Zadie Smith. When the right talks about classics or "Western" culture, these works are only important to the extent that it demonstrates their superiority, they have no interest in art in and of itself beyond that www.theguardian.com/commentisfre...
November 12, 2025 at 2:29 PM
Great piece by Zadie Smith. When the right talks about classics or "Western" culture, these works are only important to the extent that it demonstrates their superiority, they have no interest in art in and of itself beyond that www.theguardian.com/commentisfre...
That warm fuzzy feeling when you rediscover a bug in cpython that's been closed as `not planned` 🤪
November 12, 2025 at 3:28 PM
That warm fuzzy feeling when you rediscover a bug in cpython that's been closed as `not planned` 🤪
Reposted by Lee Zamparo
Are you an early-stage graduate student (2nd or 3rd year) or early-stage postdoc based in the US or Canada, working primarily in Drosophila? Would you like to help improve the experience of all trainees working in Drosophila research? If so, read on.
(Please repost to reach a broad audience.)
(Please repost to reach a broad audience.)
November 12, 2025 at 4:49 AM
Are you an early-stage graduate student (2nd or 3rd year) or early-stage postdoc based in the US or Canada, working primarily in Drosophila? Would you like to help improve the experience of all trainees working in Drosophila research? If so, read on.
(Please repost to reach a broad audience.)
(Please repost to reach a broad audience.)
Reposted by Lee Zamparo
*Urgently* looking for emergency reviewers for the ARR October Interpretability track 🙏🙏
ReSkies much appreciated
ReSkies much appreciated
November 11, 2025 at 10:29 AM
*Urgently* looking for emergency reviewers for the ARR October Interpretability track 🙏🙏
ReSkies much appreciated
ReSkies much appreciated
Reposted by Lee Zamparo
We have recently uploaded our revised manuscript “Evaluating the role of pre-training dataset size and diversity on single-cell foundation model performance”.
TL;DR: More models, more tasks => same results.
TL;DR: More models, more tasks => same results.
November 7, 2025 at 8:07 PM
We have recently uploaded our revised manuscript “Evaluating the role of pre-training dataset size and diversity on single-cell foundation model performance”.
TL;DR: More models, more tasks => same results.
TL;DR: More models, more tasks => same results.
Reposted by Lee Zamparo
How much shit will Ontario continue to eat?
"Despite Ford stating speed cameras are ineffective, regional data shows that since launching its program in February (following a pilot program that had been in place since 2021), average speeds in school zones have decreased by 15 km/h."
Waterloo Region forges ahead with speed cameras despite looming ban
The Region of Waterloo will go ahead with turning on six speed cameras despite Doug Ford’s scathing condemnation
buff.ly
November 6, 2025 at 1:46 PM
How much shit will Ontario continue to eat?
Reposted by Lee Zamparo
The way all of these people convinced themselves that Mamdani is antisemitic is a subject far more worthy of media examination than any of the ‘groupthink on campuses!’ thinkpieces we’ve been subjected to
November 5, 2025 at 8:58 PM
The way all of these people convinced themselves that Mamdani is antisemitic is a subject far more worthy of media examination than any of the ‘groupthink on campuses!’ thinkpieces we’ve been subjected to
First submission as an AE of TMLR. I hope I can do it justice 😁
November 5, 2025 at 5:12 PM
First submission as an AE of TMLR. I hope I can do it justice 😁
Reposted by Lee Zamparo
A study out today in @natgenet.nature.com from Core Investigator Luke Gilbert, Haolong Li, & others identifies PTGES3 as a critical regulator of androgen receptor (AR) protein levels in prostate cancer, revealing a potential new target for tumors that become treatment-resistant.
November 5, 2025 at 4:21 PM
A study out today in @natgenet.nature.com from Core Investigator Luke Gilbert, Haolong Li, & others identifies PTGES3 as a critical regulator of androgen receptor (AR) protein levels in prostate cancer, revealing a potential new target for tumors that become treatment-resistant.
Prosecution rests, defence may rest too? All this loafing around won't bring us to a conclusion
Day 3 of the “no more than 2” day trial of Sandwich Guy. The prosecution intends to rest; the defense hasn’t decided yet. Dispute over jury instructions continues, a few morsels (sorry) to follow.
November 5, 2025 at 4:51 PM
Prosecution rests, defence may rest too? All this loafing around won't bring us to a conclusion
Reposted by Lee Zamparo
The committee clerk email is srsr@parl.gc.ca
Messages there will be translated and circulated to the full committee.
Messages there will be translated and circulated to the full committee.
Canadian researchers should be aware the there is a motion before the Parliamentary Standing Committee on Science and Research to force Tricouncils to hand over disaggregated peer review data on all applications:
Applicant names, profiles, demographics
Reviewers names, profiles, comments, and scores
Applicant names, profiles, demographics
Reviewers names, profiles, comments, and scores
October 31, 2025 at 1:50 PM
The committee clerk email is srsr@parl.gc.ca
Messages there will be translated and circulated to the full committee.
Messages there will be translated and circulated to the full committee.
Reposted by Lee Zamparo
If you don't think rando MPs (and whoever else they share it with) should have access to personal information of individual applicants, reviewers, and students, confidential data, & full applications and reviews in every Canadian research grant (funded or not), please sign.
Yes! Contact them and sign this petition here —it’s not just about EDI data! So much personally identifying information for applicants and reviewers will not be protected!
docs.google.com/forms/d/e/1F...
docs.google.com/forms/d/e/1F...
Open Letter to Protect Tri-Council EDI Data
Why do we need urgent action to protect our data?
The mandate of the House of Commons Standing Committee on Science and Research is to review and report on topics relating to science and research in ...
docs.google.com
October 31, 2025 at 12:46 AM
If you don't think rando MPs (and whoever else they share it with) should have access to personal information of individual applicants, reviewers, and students, confidential data, & full applications and reviews in every Canadian research grant (funded or not), please sign.
Nestle Brunch
Change one letter, ruin a candy.
Bit-O-Homey
Bit-O-Homey
Change one letter, ruin a candy.
Starwurst
Starwurst
October 30, 2025 at 3:07 PM
Nestle Brunch
I absolutely applaud this, bravo!!
Started a thread in the other place and bringing it over here - I really think we should be more vocal about the opportunities that lay at the intersection of these two options!
So I'm starting a live thread of new roles as I become aware of them - feel free to add / extend / share :
So I'm starting a live thread of new roles as I become aware of them - feel free to add / extend / share :
Life situations are bleak right now for a lot of people. In tech, the "Venn Diagram" of (1) positive work and (2) making enough money to support your family is increasingly non-overlapping. We all do what we can.
This image has been living in my mind rent-free for months.
This image has been living in my mind rent-free for months.
October 30, 2025 at 2:50 AM
I absolutely applaud this, bravo!!
What the heck @sportsnetpr.bsky.social , this is the very worst time for your app to flake out. Boooooooo
October 29, 2025 at 2:22 AM
What the heck @sportsnetpr.bsky.social , this is the very worst time for your app to flake out. Boooooooo
Reposted by Lee Zamparo
Hello! The Narwhal is looking to talk to people in Canada who regularly send money home to Jamaica, Cuba, Haiti or the Bahamas and might increase it in the wake of Melissa. I am at denise@thenarwhal.ca 💚
October 28, 2025 at 9:00 PM
Hello! The Narwhal is looking to talk to people in Canada who regularly send money home to Jamaica, Cuba, Haiti or the Bahamas and might increase it in the wake of Melissa. I am at denise@thenarwhal.ca 💚