Ina Klockner 🧬👩🔬🔬
@inaklockner.bsky.social
Postdoc exploring new gene editing therapies for the neurodevelopmental disorder #AngelmanSyndrome at #UNCZylkaLab, also interested in post-transcriptional gene regulation via non-coding RNAs in neuromuscular disease |she/her|🇩🇪 🇺🇲
Amazing paper with gorgeous imaging 🔥
from @mathpreu.bsky.social
journals.biologists.com/dev/article/...
from @mathpreu.bsky.social
journals.biologists.com/dev/article/...
A developmental atlas of zebrafish gills links early vascular patterning to adult architecture
Summary: An atlas of zebrafish gill vasculature reveals developmental asymmetries and shows how early vascular patterning shapes filaments and lamellae and is reflected in adult gill architecture.
journals.biologists.com
October 31, 2025 at 9:19 PM
Amazing paper with gorgeous imaging 🔥
from @mathpreu.bsky.social
journals.biologists.com/dev/article/...
from @mathpreu.bsky.social
journals.biologists.com/dev/article/...
Reposted by Ina Klockner 🧬👩🔬🔬
Can't believe it — my first‑author paper is out and my image graces the cover of @dev-journal.bsky.social 🎉
Here, we reveal how early developmental programs shape and maintain #zebrafish gill architecture throughout life
🔗 journals.biologists.com/dev/issue/15...
#FluorescenceFriday #LifelongDevSI
Here, we reveal how early developmental programs shape and maintain #zebrafish gill architecture throughout life
🔗 journals.biologists.com/dev/issue/15...
#FluorescenceFriday #LifelongDevSI
October 31, 2025 at 10:55 AM
Can't believe it — my first‑author paper is out and my image graces the cover of @dev-journal.bsky.social 🎉
Here, we reveal how early developmental programs shape and maintain #zebrafish gill architecture throughout life
🔗 journals.biologists.com/dev/issue/15...
#FluorescenceFriday #LifelongDevSI
Here, we reveal how early developmental programs shape and maintain #zebrafish gill architecture throughout life
🔗 journals.biologists.com/dev/issue/15...
#FluorescenceFriday #LifelongDevSI
Reposted by Ina Klockner 🧬👩🔬🔬
A developmental atlas of zebrafish gills links early vascular patterning to adult architecture
Read this #LifelongDevSI #OA Research Article by Mathieu Preußner @mathpreu.bsky.social, Virginie Lecaudey @vlecaudey.bsky.social and colleagues:
journals.biologists.com/dev/article/...
Read this #LifelongDevSI #OA Research Article by Mathieu Preußner @mathpreu.bsky.social, Virginie Lecaudey @vlecaudey.bsky.social and colleagues:
journals.biologists.com/dev/article/...
October 21, 2025 at 12:36 PM
A developmental atlas of zebrafish gills links early vascular patterning to adult architecture
Read this #LifelongDevSI #OA Research Article by Mathieu Preußner @mathpreu.bsky.social, Virginie Lecaudey @vlecaudey.bsky.social and colleagues:
journals.biologists.com/dev/article/...
Read this #LifelongDevSI #OA Research Article by Mathieu Preußner @mathpreu.bsky.social, Virginie Lecaudey @vlecaudey.bsky.social and colleagues:
journals.biologists.com/dev/article/...
Reposted by Ina Klockner 🧬👩🔬🔬
My entry for today’s #FluorescenceFriday: a pupal #Drosophila testis with muscles expressing
🔵 lifeact &
🔴 RFP-nls
Honored & grateful to receive an honorable mention at @healthcare.nikon.com Nikon Small World 🌍🔬✨
🔗 www.nikonsmallworld.com/galleries/20...
#NikonSmallWorld #Microscopy #ScienceArt
🔵 lifeact &
🔴 RFP-nls
Honored & grateful to receive an honorable mention at @healthcare.nikon.com Nikon Small World 🌍🔬✨
🔗 www.nikonsmallworld.com/galleries/20...
#NikonSmallWorld #Microscopy #ScienceArt
October 3, 2025 at 9:06 AM
My entry for today’s #FluorescenceFriday: a pupal #Drosophila testis with muscles expressing
🔵 lifeact &
🔴 RFP-nls
Honored & grateful to receive an honorable mention at @healthcare.nikon.com Nikon Small World 🌍🔬✨
🔗 www.nikonsmallworld.com/galleries/20...
#NikonSmallWorld #Microscopy #ScienceArt
🔵 lifeact &
🔴 RFP-nls
Honored & grateful to receive an honorable mention at @healthcare.nikon.com Nikon Small World 🌍🔬✨
🔗 www.nikonsmallworld.com/galleries/20...
#NikonSmallWorld #Microscopy #ScienceArt
Reposted by Ina Klockner 🧬👩🔬🔬
1/12 A very special moment for me! 🎉
My first paper as corresponding author—a @jcb.org Perspective on how contact-based decision-making in collective cell migration can itself encode blueprints for complex patterns and shapes.
rupress.org/jcb/article/...
#cellbio #devbio #science
🧵for details
My first paper as corresponding author—a @jcb.org Perspective on how contact-based decision-making in collective cell migration can itself encode blueprints for complex patterns and shapes.
rupress.org/jcb/article/...
#cellbio #devbio #science
🧵for details
September 24, 2025 at 1:06 PM
1/12 A very special moment for me! 🎉
My first paper as corresponding author—a @jcb.org Perspective on how contact-based decision-making in collective cell migration can itself encode blueprints for complex patterns and shapes.
rupress.org/jcb/article/...
#cellbio #devbio #science
🧵for details
My first paper as corresponding author—a @jcb.org Perspective on how contact-based decision-making in collective cell migration can itself encode blueprints for complex patterns and shapes.
rupress.org/jcb/article/...
#cellbio #devbio #science
🧵for details
Reposted by Ina Klockner 🧬👩🔬🔬
New perspective by @maikbischoff.bsky.social & @mayorlab.bsky.social about how mesenchymal cells use contact-dependent rules to generate swarm-like behaviors, patterns & organ forms. rupress.org/jcb/article/...
#CellBio #CellMigration #Morphogenesis #Development #Science
#CellBio #CellMigration #Morphogenesis #Development #Science
September 23, 2025 at 6:45 PM
New perspective by @maikbischoff.bsky.social & @mayorlab.bsky.social about how mesenchymal cells use contact-dependent rules to generate swarm-like behaviors, patterns & organ forms. rupress.org/jcb/article/...
#CellBio #CellMigration #Morphogenesis #Development #Science
#CellBio #CellMigration #Morphogenesis #Development #Science
Reposted by Ina Klockner 🧬👩🔬🔬
We’re excited to announce the launch of our new website at angelman.org! 🎉 Our updated site features easy navigation and filters that help you find the resources, clinics, research, and support you need on any device. Check it out!➡️ angelman.org
June 26, 2025 at 9:40 PM
We’re excited to announce the launch of our new website at angelman.org! 🎉 Our updated site features easy navigation and filters that help you find the resources, clinics, research, and support you need on any device. Check it out!➡️ angelman.org
Reposted by Ina Klockner 🧬👩🔬🔬
A Boa Constrictor brain-derived cell expressing a viral glycoprotein (magenta) and stained for actin (yellow) and DNA (white).
#FluorescenceFriday
#FluorescenceFriday
June 27, 2025 at 11:20 AM
A Boa Constrictor brain-derived cell expressing a viral glycoprotein (magenta) and stained for actin (yellow) and DNA (white).
#FluorescenceFriday
#FluorescenceFriday
Reposted by Ina Klockner 🧬👩🔬🔬
FINALLY out in #Science Advances! 🎉
3 years of hard work, a fantastic team — and I’m proud to be first and co-corresponding author!
It's about Plexin signaling driving collective cell migration & organ sculpting. Check out the videos 😀
www.science.org/doi/10.1126/...
#DevBio #CellBio #Microscopy
3 years of hard work, a fantastic team — and I’m proud to be first and co-corresponding author!
It's about Plexin signaling driving collective cell migration & organ sculpting. Check out the videos 😀
www.science.org/doi/10.1126/...
#DevBio #CellBio #Microscopy
June 18, 2025 at 7:06 PM
FINALLY out in #Science Advances! 🎉
3 years of hard work, a fantastic team — and I’m proud to be first and co-corresponding author!
It's about Plexin signaling driving collective cell migration & organ sculpting. Check out the videos 😀
www.science.org/doi/10.1126/...
#DevBio #CellBio #Microscopy
3 years of hard work, a fantastic team — and I’m proud to be first and co-corresponding author!
It's about Plexin signaling driving collective cell migration & organ sculpting. Check out the videos 😀
www.science.org/doi/10.1126/...
#DevBio #CellBio #Microscopy
Reposted by Ina Klockner 🧬👩🔬🔬
For #fluorescencefriday the Mesoscopic Integrated NeuroImaging Data (MIND) platform @westernu.bsky.social presents abeta plaques and blood vessels in the 🧠 of our ApoE4 mouse model of AD. 🧪 #clearing #lightsheet 🔬 Courtesy of Arash Salahinejad, Luke Smolders and @shahrzadbahrampour.bsky.social
June 13, 2025 at 5:35 PM
For #fluorescencefriday the Mesoscopic Integrated NeuroImaging Data (MIND) platform @westernu.bsky.social presents abeta plaques and blood vessels in the 🧠 of our ApoE4 mouse model of AD. 🧪 #clearing #lightsheet 🔬 Courtesy of Arash Salahinejad, Luke Smolders and @shahrzadbahrampour.bsky.social
Stunning images!
1)
Branching morphogenesis is fundamental to animal development, shaping complex organs like lungs, kidneys, and vascular networks. Gills are another highly branched organ. Yet, the developmental processes behind gill formation in zebrafish remain poorly understood.
#zebrafish #gills #microscopy
Branching morphogenesis is fundamental to animal development, shaping complex organs like lungs, kidneys, and vascular networks. Gills are another highly branched organ. Yet, the developmental processes behind gill formation in zebrafish remain poorly understood.
#zebrafish #gills #microscopy
June 6, 2025 at 5:09 PM
Stunning images!
Reposted by Ina Klockner 🧬👩🔬🔬
1)
Branching morphogenesis is fundamental to animal development, shaping complex organs like lungs, kidneys, and vascular networks. Gills are another highly branched organ. Yet, the developmental processes behind gill formation in zebrafish remain poorly understood.
#zebrafish #gills #microscopy
Branching morphogenesis is fundamental to animal development, shaping complex organs like lungs, kidneys, and vascular networks. Gills are another highly branched organ. Yet, the developmental processes behind gill formation in zebrafish remain poorly understood.
#zebrafish #gills #microscopy
June 6, 2025 at 4:12 PM
1)
Branching morphogenesis is fundamental to animal development, shaping complex organs like lungs, kidneys, and vascular networks. Gills are another highly branched organ. Yet, the developmental processes behind gill formation in zebrafish remain poorly understood.
#zebrafish #gills #microscopy
Branching morphogenesis is fundamental to animal development, shaping complex organs like lungs, kidneys, and vascular networks. Gills are another highly branched organ. Yet, the developmental processes behind gill formation in zebrafish remain poorly understood.
#zebrafish #gills #microscopy
Reposted by Ina Klockner 🧬👩🔬🔬
Gills just wanna have #FluorescenceFriday 🎵
Phalloidin reveals the beauty of the filament's distal tip in cleared gills of adult 🦓🐟
#microscopy #devbio #sciart
Phalloidin reveals the beauty of the filament's distal tip in cleared gills of adult 🦓🐟
#microscopy #devbio #sciart
April 11, 2025 at 4:20 PM
Gills just wanna have #FluorescenceFriday 🎵
Phalloidin reveals the beauty of the filament's distal tip in cleared gills of adult 🦓🐟
#microscopy #devbio #sciart
Phalloidin reveals the beauty of the filament's distal tip in cleared gills of adult 🦓🐟
#microscopy #devbio #sciart
Reposted by Ina Klockner 🧬👩🔬🔬
Reposted by Ina Klockner 🧬👩🔬🔬
I know, it's a bit late for #FluorescenceFriday but I want to share my new banner :D
#cellmigration #cellbio #devbio #sciart #microcosm #science
#cellmigration #cellbio #devbio #sciart #microcosm #science
March 28, 2025 at 9:39 PM
I know, it's a bit late for #FluorescenceFriday but I want to share my new banner :D
#cellmigration #cellbio #devbio #sciart #microcosm #science
#cellmigration #cellbio #devbio #sciart #microcosm #science
Reposted by Ina Klockner 🧬👩🔬🔬
I begrudgingly admit that actin is pretty cool 🤩
🎥 Primary mouse myotubes labeled with Lifeact-mScarlet-I3 (cyan) and H2B-mStayGreen (red). #FluorescenceFriday
🎥 Primary mouse myotubes labeled with Lifeact-mScarlet-I3 (cyan) and H2B-mStayGreen (red). #FluorescenceFriday
March 22, 2025 at 5:15 AM
I begrudgingly admit that actin is pretty cool 🤩
🎥 Primary mouse myotubes labeled with Lifeact-mScarlet-I3 (cyan) and H2B-mStayGreen (red). #FluorescenceFriday
🎥 Primary mouse myotubes labeled with Lifeact-mScarlet-I3 (cyan) and H2B-mStayGreen (red). #FluorescenceFriday
Reposted by Ina Klockner 🧬👩🔬🔬
2/4 I chose this picture because I am interested in an old question:
How do fly testes obtain their specific shape?
In my previous research I learned that muscle precursors shape it, using collective cell migration and alignement to achieve the pattern visible in this picture.
How do fly testes obtain their specific shape?
In my previous research I learned that muscle precursors shape it, using collective cell migration and alignement to achieve the pattern visible in this picture.
March 11, 2025 at 12:03 PM
2/4 I chose this picture because I am interested in an old question:
How do fly testes obtain their specific shape?
In my previous research I learned that muscle precursors shape it, using collective cell migration and alignement to achieve the pattern visible in this picture.
How do fly testes obtain their specific shape?
In my previous research I learned that muscle precursors shape it, using collective cell migration and alignement to achieve the pattern visible in this picture.
Reposted by Ina Klockner 🧬👩🔬🔬
Stand up for science Raleigh!! Let’s keep this energy going!!
March 8, 2025 at 3:13 AM
Stand up for science Raleigh!! Let’s keep this energy going!!
Reposted by Ina Klockner 🧬👩🔬🔬
Mesonephric glomeruli of #zebrafish for #FluorescenceFriday 🔬
kdrl-mCherry nicely reveals the capillary tuft of the glomerulus.
The zebrafish kidney stops developing at the mesonephros stage! It serves as their main kidney structure, and they don't develop a metanephros like humans do.
kdrl-mCherry nicely reveals the capillary tuft of the glomerulus.
The zebrafish kidney stops developing at the mesonephros stage! It serves as their main kidney structure, and they don't develop a metanephros like humans do.
February 28, 2025 at 4:48 PM
Mesonephric glomeruli of #zebrafish for #FluorescenceFriday 🔬
kdrl-mCherry nicely reveals the capillary tuft of the glomerulus.
The zebrafish kidney stops developing at the mesonephros stage! It serves as their main kidney structure, and they don't develop a metanephros like humans do.
kdrl-mCherry nicely reveals the capillary tuft of the glomerulus.
The zebrafish kidney stops developing at the mesonephros stage! It serves as their main kidney structure, and they don't develop a metanephros like humans do.
Reposted by Ina Klockner 🧬👩🔬🔬
For today's #fluorescencefriday I have a riddle 😊. Can anyone who is knowledgeable in #Drosophila #neuroscience tell my what these are? I honestly don't know! Overview picture in the comments-they are from the brain🧠🪰. The marker is lifeact::GFP, depth-coded...
#sciart #microscopy #cellbio #cellfy🔬
#sciart #microscopy #cellbio #cellfy🔬
February 28, 2025 at 7:03 PM
For today's #fluorescencefriday I have a riddle 😊. Can anyone who is knowledgeable in #Drosophila #neuroscience tell my what these are? I honestly don't know! Overview picture in the comments-they are from the brain🧠🪰. The marker is lifeact::GFP, depth-coded...
#sciart #microscopy #cellbio #cellfy🔬
#sciart #microscopy #cellbio #cellfy🔬
Reposted by Ina Klockner 🧬👩🔬🔬
An ancient unpublished picture from my PhD
#FluorescenceFriday!
Drosophila sperm pump depth-coded
with muscles (phalloidin=cyan/green) + Dapi (yellow/red).
Not confocal but an old Zeiss Apotome - which is still an awesome scope! #sciart #microscopy #bioart #sciart #microscopyart #cellbio #devbio
#FluorescenceFriday!
Drosophila sperm pump depth-coded
with muscles (phalloidin=cyan/green) + Dapi (yellow/red).
Not confocal but an old Zeiss Apotome - which is still an awesome scope! #sciart #microscopy #bioart #sciart #microscopyart #cellbio #devbio
February 7, 2025 at 2:02 PM
An ancient unpublished picture from my PhD
#FluorescenceFriday!
Drosophila sperm pump depth-coded
with muscles (phalloidin=cyan/green) + Dapi (yellow/red).
Not confocal but an old Zeiss Apotome - which is still an awesome scope! #sciart #microscopy #bioart #sciart #microscopyart #cellbio #devbio
#FluorescenceFriday!
Drosophila sperm pump depth-coded
with muscles (phalloidin=cyan/green) + Dapi (yellow/red).
Not confocal but an old Zeiss Apotome - which is still an awesome scope! #sciart #microscopy #bioart #sciart #microscopyart #cellbio #devbio
Reposted by Ina Klockner 🧬👩🔬🔬
Wow! We got the cover! #MBOC #ASCB #CellBio
So proud of #TeamTestis. Screening <270 lines for shape defects was a huge team effort!
I created this collage from the team’s images from the past 2 years! Depth-color-coded with Fiji. Inspired by late 19th century lithographic animal illustrations.
So proud of #TeamTestis. Screening <270 lines for shape defects was a huge team effort!
I created this collage from the team’s images from the past 2 years! Depth-color-coded with Fiji. Inspired by late 19th century lithographic animal illustrations.
January 30, 2025 at 4:17 PM
Wow! We got the cover! #MBOC #ASCB #CellBio
So proud of #TeamTestis. Screening <270 lines for shape defects was a huge team effort!
I created this collage from the team’s images from the past 2 years! Depth-color-coded with Fiji. Inspired by late 19th century lithographic animal illustrations.
So proud of #TeamTestis. Screening <270 lines for shape defects was a huge team effort!
I created this collage from the team’s images from the past 2 years! Depth-color-coded with Fiji. Inspired by late 19th century lithographic animal illustrations.
Reposted by Ina Klockner 🧬👩🔬🔬
🔬My first try on #FluorescenceFriday
Nice detail of a tissue-cleared kidney from neonatal mice.
-GFP is expressed in podocytes and pericytes.
-CD31 antibody highlights the branched blood vessels and glomeruli in red
Nice detail of a tissue-cleared kidney from neonatal mice.
-GFP is expressed in podocytes and pericytes.
-CD31 antibody highlights the branched blood vessels and glomeruli in red
December 20, 2024 at 7:08 PM
🔬My first try on #FluorescenceFriday
Nice detail of a tissue-cleared kidney from neonatal mice.
-GFP is expressed in podocytes and pericytes.
-CD31 antibody highlights the branched blood vessels and glomeruli in red
Nice detail of a tissue-cleared kidney from neonatal mice.
-GFP is expressed in podocytes and pericytes.
-CD31 antibody highlights the branched blood vessels and glomeruli in red
Reposted by Ina Klockner 🧬👩🔬🔬
How proximal is proximity labeling❓ Using DNA nanorulers we found that TurboID/BioID are largely contact labeling, while APEX2 also bears a major contact labeling pathway in parallel with diffusive labeling.
www.biorxiv.org/content/10.1...
Special thanks to @aliceyting.bsky.social for discussions
www.biorxiv.org/content/10.1...
Special thanks to @aliceyting.bsky.social for discussions
December 19, 2024 at 2:22 AM
How proximal is proximity labeling❓ Using DNA nanorulers we found that TurboID/BioID are largely contact labeling, while APEX2 also bears a major contact labeling pathway in parallel with diffusive labeling.
www.biorxiv.org/content/10.1...
Special thanks to @aliceyting.bsky.social for discussions
www.biorxiv.org/content/10.1...
Special thanks to @aliceyting.bsky.social for discussions
Reposted by Ina Klockner 🧬👩🔬🔬
Muscles growth by sarcomere divisions - how your muscles add new sarcomeres during developmental growth: they divide! Cool collaboration @friedrich-group.bsky.social @raunser-lab.bsky.social @Dirk Görlich @univ-amu.fr @cnrs.bsky.social sciencecast.org/casts/aspy9l... www.biorxiv.org/content/10.1...
December 19, 2024 at 10:10 AM
Muscles growth by sarcomere divisions - how your muscles add new sarcomeres during developmental growth: they divide! Cool collaboration @friedrich-group.bsky.social @raunser-lab.bsky.social @Dirk Görlich @univ-amu.fr @cnrs.bsky.social sciencecast.org/casts/aspy9l... www.biorxiv.org/content/10.1...