Mathieu Preußner
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mathpreu.bsky.social
Mathieu Preußner
@mathpreu.bsky.social
750 followers 1K following 150 posts
PhD in the lab of @vlecaudey.bsky.social at JGU. Developmental Biology in #Zebrafish.
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mathpreu.bsky.social
Mathieu Preußner @mathpreu.bsky.social · Oct 31
Can't believe it — my first‑author paper is out and my image graces the cover of @dev-journal.bsky.social 🎉

Here, we reveal how early developmental programs shape and maintain #zebrafish gill architecture throughout life
🔗 journals.biologists.com/dev/issue/15...

#FluorescenceFriday #LifelongDevSI
mathpreu.bsky.social
2/2 zooming in for a more detailed look on lamellae
February 13, 2026 at 3:35 PM
mathpreu.bsky.social
1/2
Happy #FluorescenceFriday 🔬
Another cryosection of a dissected zebrafish gill:
⚪Phalloidin
🔵DAPI
February 13, 2026 at 3:35 PM
Reposted by Mathieu Preußner
kwolbachia.bsky.social
Experimental #FluorescenceFriday today : This is the head of a tiny fig wasp imaged in 3D with confocal microscopy, color gradient indicates depth. Cross your eyes and let the images overlap for a cool 3D effect!
#Sciart
February 6, 2026 at 2:42 PM
Reposted by Mathieu Preußner
dev-journal.bsky.social
Submit your latest research to our upcoming special issue – The Extracellular Environment in Development, Regeneration and Stem Cells

Guest Editors: Alex Hughes (@hugheslabpenn.bsky.social) & Rashmi Priya (@rashmi-priya.bsky.social)

Deadline: 1 March 2026

journals.biologists.com/dev/pages/ex...
Special Issue The Extracellular Environment in Development, Regeneration and Stem Cells Guest Editors Alex Hughes (University of Pennsylvania) Rashmi Priya (The Francis Crick Institute) Submission deadline: 1 March 2026. Development call for papers. Image of magenta and teal cells in a jawbone.
February 10, 2026 at 4:24 PM
Reposted by Mathieu Preußner
reproductionms.bsky.social
🔬Join our #ReproductionMS seminar with Dr.
@maikbischoff.bsky.social on "Coiling a Duct: How Mesenchymal Cells Sculpt Male Reproductive Organ Architecture" this Wednesday, 11 February 12pm CET. DM for Zoom details.
February 9, 2026 at 10:22 AM
Reposted by Mathieu Preußner
stowersinstitute.bsky.social
This week’s #MicroscopyMonday features a confocal microscopy image that shows cell nuclei in zebrafish skin (blue) and different types of skin ionocytes (magenta, orange). 🔬 (Piotrowski Lab)
February 9, 2026 at 5:47 PM
Reposted by Mathieu Preußner
aaandmoore.bsky.social
Not something you see in textbooks very often: tripolar mitosis.
February 7, 2026 at 8:00 AM
Reposted by Mathieu Preußner
tobyandrews.bsky.social
Job alert! 📣 I’m looking for a research assistant to join my new team @idrm.ox.ac.uk

Were using #zebrafish to understand gene-environment interactions that shape the heart 🫀generate natural diversity 🐸🐭 and contribute to congenital defects ❤️‍🩹

Full info below, and please share! 🫶🏻

bit.ly/467TO0M
February 2, 2026 at 2:01 PM
Reposted by Mathieu Preußner
emboreports.org
Christian Helker @unimarburg.bsky.social and co-workers show that apelin signaling acts as a molecular switch between endothelial and hematopoietic #stemcells.

link.springer.com/article/10.1...

Highlight by @labmonteiro.bsky.social @unibirmingham.bsky.social

link.springer.com/article/10.1...
January 26, 2026 at 5:16 PM
Reposted by Mathieu Preußner
zebrafishrock.bsky.social
Adult zebrafish gill vasculature. Credit to @mathpreu.bsky.social. #ZebrafishZunday 🧪
Maximum intensity projection showing dorsal vasculature of the first gill arch of a CUBIC-cleared adult kdrl:mCherry zebrafish. Fluorescent signal was pseudocoloured using the PBIYC lookup table in ImageJ. Analysis of this endothelial reporter enabled detailed mapping of gill vascular development and revealed distinct medial and lateral filament types. Credit text to the journal Development. See Research Article by Preußner et al. https://doi.org/10.1242/dev.204984
February 1, 2026 at 1:09 PM
mathpreu.bsky.social
Wow 😍
Thanks for sharing 🤝
February 1, 2026 at 3:05 PM
Reposted by Mathieu Preußner
cellsdev.bsky.social
A fascinating review on the role of Activin in organ induction. Isn't it wild that in Xenopus embryos, a piece of the animal cap can be induced with Activin at different concentrations and buffers to form the ❤️, kidney, the pancreas, head, tail, and even a whole embryoid 🤯:
doi.org/10.1016/j.cd...
Fig. 1. Animal cap assay and sandwich method as in vitro induction systems. In amphibians, a blastocoel cavity clearly forms inside the animal hemisphere during the blastula and early gastrula stages. The cap-like portion lining the roof of the blastocoel cavity is the animal cap. This region consists of a sheet of pluripotent cells, organized into one or several layers. In the animal cap assay, the animal cap was treated with a physiological saline solution containing inducing factors and then cultured. Depending on the type, concentration, and duration of exposure to the inducing factors, animal caps can differentiate into various cell types. In contrast, the sandwich method, involves culturing the inducer source in between two animal caps. In this technique, the sources of induction can include the dorsal lip of the blastopore (organizer), adult tissues, pelletized soluble factors, or animal caps pretreated with soluble factors. In this figure, activin is used as an example of an inducing factor. Fig. 12. Summary of the in vitro induction system using activin as an inducing factor. This in vitro induction system utilizes activin and retinoic acid as inducing factors to treat animal caps, employing techniques such as animal cap assay, dissociation/reaggregation protocol, and the sandwich method. By applying these methods, various levels of self-organization can be replicated and controlled in vitro, ranging from lower-order cell differentiation to higher-order tissue differentiation, organogenesis, and even the formation of fundamental body plans. Abbreviations: Dorsal [D], ventral [V], and retinoic acid [RA]. Fig. 11. Formation of embryoids by artificial activin concentration gradients. To create embryoids, animal caps were prepared through treatment with low (0.5–1 ng/ml), intermediate (5–10 ng/ml), or high (50–100 ng/ml) concentrations of activin. These three types of activin-treated animal caps were then sequentially arranged and cultured with untreated animal caps. After 3 days of culture, embryoids with distinct head and trunk-tail structures were formed (A). Histological sections revealed differentiation into head tissues, such as the cement gland [cg] and eyes, and trunk-tail tissues including the ear vesicle [ev], brain [br], notochord [not], muscle [mus], and gut (B). When newt embryos are used in similar combination cultures, neural plate structures forming the brain [white arrow] and axial structures forming the trunk-tail regions [black arrow] are sometimes observed (C). Fig. 7. In vitro heart formation and in vivo transplantation experiment. When treated with a high concentration of activin, the animal caps of Xenopus embryos did not differentiate into heart tissue. However, if the animal cap dissociates into individual cells before activin treatment and then reaggregates, it forms a beating heart [arrow] with 100 % efficiency (A). This heart expresses differentiation marker genes, such as Nkx2.5, GATA-4, Tbx5, MHCα, TnIc (cardiac troponin I), and ANF, none of which are expressed in an animal cap treated with activin alone, without dissociation/reaggregation (B). Electron microscopy reveals the presence of intercalated discs [id] specific to the cardiac muscle, along with visible mitochondria [m] and Z-bands [z] (C). When the reaggregated heart tissue is orthotopically transplanted into the cardiac primordium of a neurula-stage embryo, it integrates without rejection and continues to beat (D), although it does not persist through host metamorphosis. In contrast, when the reaggregated tissue is ectopically transplanted into the ventral region of the neurula, it begins to beat synchronously with the host heart and gradually reddens as it initiates blood circulation (E).
January 31, 2026 at 6:39 PM
Reposted by Mathieu Preußner
melaniedwhite.bsky.social
This developing quail embryo looks like it's thinking fiery thoughts for #FluorescenceFriday 🐣🔥🧪. Imaged by the fantastic @vanderspuy.bsky.social
January 30, 2026 at 3:34 AM
Reposted by Mathieu Preußner
lazaroillustration.bsky.social
Illustration of sword-tailed newt #art #wildlife #nature
Illustration of sword-tailed newt
January 28, 2026 at 7:00 PM
Reposted by Mathieu Preußner
biodiversitypix.bsky.social
🦜 A monograph of the Ramphastidae, or family of toucans
London: Published by the author, 20, Broad Street, Golden Square, [1852]-1854.

[Source]
Illustration of a toucan (Ramphastos Inca) perched on a tree branch with green and brown leaves. The bird features a large, prominently curved yellow and black beak, blue skin around its eyes, a white throat, a red band across its chest, and predominantly black plumage with red and yellow accents near its tail. The background shows a faint, misty forest scene. The style reflects a detailed 19th-century natural history illustration.
January 27, 2026 at 7:23 AM
Reposted by Mathieu Preußner
maikbischoff.bsky.social
🚨 The deadline has been extended until January 31st!🚨
maikbischoff.bsky.social Maik Bischoff @maikbischoff.bsky.social · Dec 15
🚨 PhD Position Available 🚨
I’m recruiting a PhD student to join my lab at the Multiscale Imaging Centre (MIC), Münster, Germany.

www.bischofflab.com/jobs

Fully funded ✅
#Cellbio #Morphogenesis #Microscopy
#Drosophila #PhD
(Details Below)

Original Posting:
stellen.uni-muenster.de/jobposting/d...
January 19, 2026 at 12:20 PM
Reposted by Mathieu Preußner
zebrafishrock.bsky.social
We spy a few #zebrafish peeps as invited speakers 🤩
sfb1348.bsky.social SFB 1348 @sfb1348.bsky.social · Jan 14
Cellular Interfaces reloaded: Join us for the @sfb1348.bsky.social International Meeting on „Mechanochemical signals at cellular interfaces" in Münster from May 27–29, 2026.
Registration opens in February! Limited spots – first come, first serve! More info: tinyurl.com/ypyzd23w
@uni-muenster.de
January 17, 2026 at 2:01 PM
Reposted by Mathieu Preußner
kwolbachia.bsky.social
Another pine pollen for #FluorescenceFriday! It seems that this year too, I still won't get tired of colour coding my microscopy 🧡💜💙💚❤️
January 9, 2026 at 5:34 PM
Reposted by Mathieu Preußner
martinowk.bsky.social
For #FluorescenceFriday some co-cultured astrocytes 🟢 and neurons 🔴 that ended up looking super cool from the @lieberinstitute.bsky.social Imaging Development group 🔬🤩🧪🧠
January 9, 2026 at 12:06 PM
mathpreu.bsky.social
Congratulations 🎉
January 8, 2026 at 5:01 PM
Reposted by Mathieu Preußner
inaklockner.bsky.social
New paper out 🔥!

Small promoter, big potential🧬 We show that the ultra-compact Calm1 promoter efficiently targets human neurons in brain organoids and is a promising alternative to hSyn for AAV gene delivery.

Huge thanks to everyone who contributed to this work!
🧠 📄: www.nature.com/articles/s41...
Compact Calm1 promoter enables AAV mediated neuron-targeted expression in human iPSC-derived brain organoids - Scientific Reports
Scientific Reports - Compact Calm1 promoter enables AAV mediated neuron-targeted expression in human iPSC-derived brain organoids
www.nature.com
January 5, 2026 at 12:37 PM
Reposted by Mathieu Preußner
maikbischoff.bsky.social
There is still over a week left to apply.
Please send your documents to maik.bischoff@uni-muenster.de
maikbischoff.bsky.social Maik Bischoff @maikbischoff.bsky.social · Jan 6
Join us to study developmental cell biology with a focus on cell migration and morphogenesis.

More info about our research:
www.bischofflab.com

Job posting and application details:
focalplane.biologists.com/cell-biology...

#Science #CellBio #DevBio #AcademicJobs #PhDJobs #PhDPosition #Drosophila
January 6, 2026 at 12:43 PM
Reposted by Mathieu Preußner
maikbischoff.bsky.social
Morphogenesis & Organogenesis!
Part 1 (full) in the comments 👇

Comment if you'd like to be added (regardless of age or career stage!)

Please post your own biology-related starter packs using #BioStarterPacks

🧬🔬🪰🐟🐁🌱
June 26, 2025 at 9:40 PM
Reposted by Mathieu Preußner
natclarke.bsky.social
Felt a little festive at the microscope this morning for #FluorescenceFriday 🎄

Here’s the nervous system of a juvenile sea star ⭐️

Green = acetylated tubulin, red = nuclei

Happy holidays!
Confocal microscopy image of a juvenile sea star (Patiria miniata) viewed from the oral side. The animal has a five-armed, star-shaped body with a central nerve ring. The nervous system is labeled in green, forming radial nerve cords extending into each arm, and cell nuclei are labeled in red throughout the animal. The image appears against a black background and has a holiday-ornament-like appearance.
December 19, 2025 at 5:32 PM
mathpreu.bsky.social
As a biologist working on the cellular and molecular development of gills, I love seeing gill architecture inspire solutions like this plastic-filtering technology....truly inspiring 🦓🐟🔬
basicthinking.de BASIC thinking @basicthinking.de · Dec 17
Mikroplastik stellt eine große Belastung für Mensch und Natur dar. Forscher haben nun einen Mikroplastikfilter für Waschmaschinen entwickelt, der sich an den Kiemen von Fischen orientiert. So können selbst winzige Kunststoffpartikel besonders effizient aus dem Abwasser gefiltert werden.
Forscher entwickeln neuartigen Mikroplastikfilter für Waschmaschine
Forscher haben einen Mikroplastikfilter entwickelt, der sich an Kiemen von Fischen orientiert und Kunststoffpartikel aus Abwasser filtert.
www.basicthinking.de
December 18, 2025 at 8:14 AM