Frank Schnorrer
@frankschnorrer.bsky.social
Developmental & cell biologist @IBDM and @Centuri in Marseille. Studying muscle making and maintenance in Drosophila and in culture.
Passionate cyclist.
Passionate cyclist.
Pinned
SARCOMERES divide! Mechanism how muscles grow while contracting - daughter sarcomeres appear everywhere. Seen live, registered on our cover. Pioneered by @clementrodier.bsky.social @friedrich-group.bsky.social Ian Estabrook @ibdm.bsky.social $ by @hfspo.bsky.social www.science.org/doi/10.1126/...
On the cover - Congrats @jeromeavellaneda.bsky.social @nunoluis.bsky.social
flies fly! @fly-eds.bsky.social www.cell.com/developmenta...
flies fly! @fly-eds.bsky.social www.cell.com/developmenta...
November 3, 2025 at 5:22 PM
On the cover - Congrats @jeromeavellaneda.bsky.social @nunoluis.bsky.social
flies fly! @fly-eds.bsky.social www.cell.com/developmenta...
flies fly! @fly-eds.bsky.social www.cell.com/developmenta...
Reposted by Frank Schnorrer
Nature suggests you use their "Manuscript Adviser" bot to get advice before submitting
I uploaded the classic Watson & Crick paper about DNA structure, and the Adviser had this to say about one of the greatest paper endings of the century:
I uploaded the classic Watson & Crick paper about DNA structure, and the Adviser had this to say about one of the greatest paper endings of the century:
November 3, 2025 at 1:55 PM
Nature suggests you use their "Manuscript Adviser" bot to get advice before submitting
I uploaded the classic Watson & Crick paper about DNA structure, and the Adviser had this to say about one of the greatest paper endings of the century:
I uploaded the classic Watson & Crick paper about DNA structure, and the Adviser had this to say about one of the greatest paper endings of the century:
Reposted by Frank Schnorrer
There's an update on the state of FlyBase on the FlyBase.org front page. You can contribute to FlyBase at this link wiki.flybase.org/wiki/FlyBase...
We express enormous gratitude to the people, labs, groups, and foundations who have already helped us.
#FlyBase #Drosophila
We express enormous gratitude to the people, labs, groups, and foundations who have already helped us.
#FlyBase #Drosophila
October 3, 2025 at 6:19 PM
There's an update on the state of FlyBase on the FlyBase.org front page. You can contribute to FlyBase at this link wiki.flybase.org/wiki/FlyBase...
We express enormous gratitude to the people, labs, groups, and foundations who have already helped us.
#FlyBase #Drosophila
We express enormous gratitude to the people, labs, groups, and foundations who have already helped us.
#FlyBase #Drosophila
Reposted by Frank Schnorrer
We close the day at #25EngLife with an inspiring talk by @frankschnorrer.bsky.social Titin rules!
September 2, 2025 at 3:33 PM
We close the day at #25EngLife with an inspiring talk by @frankschnorrer.bsky.social Titin rules!
Read about how female muscles grow larger than male ones! and hearts too!
Excited to share our new preprint on bioRxiv: "Cell type specific allometry controls sex-differences in Drosophila body size"!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Cell type specific allometry controls sex-differences in Drosophila body size
Species and sex-specific differences in organ size are fundamental features of animal biology, yet the mechanisms that drive these differences remain debated. Adult female Drosophila are larger than m...
www.biorxiv.org
August 29, 2025 at 2:00 PM
Read about how female muscles grow larger than male ones! and hearts too!
Females are larger than males. How? Here is one solution- they have MORE nuclei in their flight muscles and grow LARGER heart and fat body cells with MORE ribosomal mRNAs. Fun collaboration of @jeromeavellaneda.bsky.social with @soumitrakp.bsky.social & Brian Oliver www.biorxiv.org/content/10.1...
August 29, 2025 at 1:57 PM
Females are larger than males. How? Here is one solution- they have MORE nuclei in their flight muscles and grow LARGER heart and fat body cells with MORE ribosomal mRNAs. Fun collaboration of @jeromeavellaneda.bsky.social with @soumitrakp.bsky.social & Brian Oliver www.biorxiv.org/content/10.1...
Microtubules: the architect of muscles. Watch how microtubules transport mitochondria in proximity to energy consuming sarcomeres in muscles of flies and mice. @jeromeavellaneda.bsky.social @nunoluis.bsky.social @ibdm.bsky.social with @gomeslabo.bsky.social www.sciencedirect.com/science/arti...
July 21, 2025 at 12:52 PM
Microtubules: the architect of muscles. Watch how microtubules transport mitochondria in proximity to energy consuming sarcomeres in muscles of flies and mice. @jeromeavellaneda.bsky.social @nunoluis.bsky.social @ibdm.bsky.social with @gomeslabo.bsky.social www.sciencedirect.com/science/arti...
SARCOMERES divide! Mechanism how muscles grow while contracting - daughter sarcomeres appear everywhere. Seen live, registered on our cover. Pioneered by @clementrodier.bsky.social @friedrich-group.bsky.social Ian Estabrook @ibdm.bsky.social $ by @hfspo.bsky.social www.science.org/doi/10.1126/...
July 10, 2025 at 10:16 AM
SARCOMERES divide! Mechanism how muscles grow while contracting - daughter sarcomeres appear everywhere. Seen live, registered on our cover. Pioneered by @clementrodier.bsky.social @friedrich-group.bsky.social Ian Estabrook @ibdm.bsky.social $ by @hfspo.bsky.social www.science.org/doi/10.1126/...
Reposted by Frank Schnorrer
Visualising where different genes are switched on throughout a fly
📷 @jasperjanssens.bsky.social et al @steinaerts.bsky.social
@cbdresearch.bsky.social @frankschnorrer.bsky.social
@centuri-ls.bsky.social in @elife.bsky.social
➡️ bpod.org.uk/archive/2025/5/14 with @DrJohnAnkers
📷 @jasperjanssens.bsky.social et al @steinaerts.bsky.social
@cbdresearch.bsky.social @frankschnorrer.bsky.social
@centuri-ls.bsky.social in @elife.bsky.social
➡️ bpod.org.uk/archive/2025/5/14 with @DrJohnAnkers
May 14, 2025 at 3:23 PM
Visualising where different genes are switched on throughout a fly
📷 @jasperjanssens.bsky.social et al @steinaerts.bsky.social
@cbdresearch.bsky.social @frankschnorrer.bsky.social
@centuri-ls.bsky.social in @elife.bsky.social
➡️ bpod.org.uk/archive/2025/5/14 with @DrJohnAnkers
📷 @jasperjanssens.bsky.social et al @steinaerts.bsky.social
@cbdresearch.bsky.social @frankschnorrer.bsky.social
@centuri-ls.bsky.social in @elife.bsky.social
➡️ bpod.org.uk/archive/2025/5/14 with @DrJohnAnkers
Reposted by Frank Schnorrer
The amazing tour de force of the great @lcferme.bsky.social is now out in its final form in @ScienceAdvances (not on Bluesky???). It was hard work and all the conceptual advance was her doing. Check it out: www.science.org/doi/epdf/10....
Timely neurogenesis drives the transition from nematic to crystalline nuclear packing during retinal morphogenesis
You have to enable JavaScript in your browser's settings in order to use the eReader.
www.science.org
May 10, 2025 at 8:40 AM
The amazing tour de force of the great @lcferme.bsky.social is now out in its final form in @ScienceAdvances (not on Bluesky???). It was hard work and all the conceptual advance was her doing. Check it out: www.science.org/doi/epdf/10....
Titin evolution, titin force and muscle contraction instruct sarcomere dimensions in insect muscles to allow high frequency flight, larval crawling and max force to cut leafs. @ibdm.bsky.social @mpi-nat.bsky.social @jfrupprecht.bsky.social @vincent-loreau.bsky.social
www.science.org/doi/epdf/10....
www.science.org/doi/epdf/10....
May 10, 2025 at 11:15 AM
Titin evolution, titin force and muscle contraction instruct sarcomere dimensions in insect muscles to allow high frequency flight, larval crawling and max force to cut leafs. @ibdm.bsky.social @mpi-nat.bsky.social @jfrupprecht.bsky.social @vincent-loreau.bsky.social
www.science.org/doi/epdf/10....
www.science.org/doi/epdf/10....
😀 looking forward to continuing our collaboration
Fully-funded PhD position at @poldresden.bsky.social in Dresden, Germany, to theoretically study sarcomere self-assembly in muscle cells, in collaboration with the experimental group of Frank Schnorrer @frankschnorrer.bsky.social
More information here:
physics-of-life.tu-dresden.de/friedrich
More information here:
physics-of-life.tu-dresden.de/friedrich
April 6, 2025 at 8:08 PM
😀 looking forward to continuing our collaboration
Reposted by Frank Schnorrer
Great Dispatch article by @tarafinegan.bsky.social on our new paper by @theajacobs.bsky.social in @currentbiology.bsky.social - thanks for condensing our findings so clearly and nicely!
Epithelial biology: Holding the corners together: shorturl.at/cMziC
@sfb1348.bsky.social @uni-muenster.de
Epithelial biology: Holding the corners together: shorturl.at/cMziC
@sfb1348.bsky.social @uni-muenster.de
Epithelial biology: Holding the corners together
A new study reveals that the Drosophila follicular epithelium opens its permeability
barrier to allow passage of yolk to the oocyte by relaxing, not actively pulling open,
cell vertices. This work res...
www.cell.com
March 24, 2025 at 3:15 PM
Great Dispatch article by @tarafinegan.bsky.social on our new paper by @theajacobs.bsky.social in @currentbiology.bsky.social - thanks for condensing our findings so clearly and nicely!
Epithelial biology: Holding the corners together: shorturl.at/cMziC
@sfb1348.bsky.social @uni-muenster.de
Epithelial biology: Holding the corners together: shorturl.at/cMziC
@sfb1348.bsky.social @uni-muenster.de
Fly group leaders in Eastern Europe, UK, France, Germany, Switzerland/Austria, please step forward. The European Fly community needs your help. #Drosophila #EDRC
European Drosophila Board election call for nominations. Join the EDB to represent and support Drosophila research in Europe! Five representatives will be elected for different regions. Check our election page for details:
europeandrosophilasociety.org/european-dro...
#Drosophila, #EDRC2025
europeandrosophilasociety.org/european-dro...
#Drosophila, #EDRC2025
March 18, 2025 at 12:20 PM
Fly group leaders in Eastern Europe, UK, France, Germany, Switzerland/Austria, please step forward. The European Fly community needs your help. #Drosophila #EDRC
Reposted by Frank Schnorrer
💪🇺🇸🇫🇷
Press release from Stand Up For Science France (cc @standupforscience.bsky.social)
March 6, 2025 at 6:57 PM
💪🇺🇸🇫🇷
Spatial transcriptomics in fly brain and body. Wonderful collaboration with @steinaerts.bsky.social led by @jasperjanssens.bsky.social @pierremangeol.bsky.social Nikolai Hecker & Gabriele Partel - look at mRNA patterns in muscles and brains spatialfly.aertslab.org
elifesciences.org/reviewed-pre...
elifesciences.org/reviewed-pre...
March 6, 2025 at 8:58 AM
Spatial transcriptomics in fly brain and body. Wonderful collaboration with @steinaerts.bsky.social led by @jasperjanssens.bsky.social @pierremangeol.bsky.social Nikolai Hecker & Gabriele Partel - look at mRNA patterns in muscles and brains spatialfly.aertslab.org
elifesciences.org/reviewed-pre...
elifesciences.org/reviewed-pre...
#PodcastCNRS 🎧 Quels mécanismes sont impliqués dans la fonte musculaire lors d’une maladie ou en vieillissant ? Bianca Habermann, tente de répondre en observant les mitochondries, siège de la fabrication de notre énergie !
👉 smartlink.ausha.co/cnrs-qu-est-...
👉 smartlink.ausha.co/cnrs-qu-est-...
February 4, 2025 at 4:08 PM
Reposted by Frank Schnorrer
Interested in the cell biology of the nucleus? Join us for this unique exciting meeting that covers everything from nuclear biophysics and mechanics to signaling and evolution😍 amazing speaker list and more will be selected from abstracts 🤩
📣 Join us for #EESNucleus 🧬
Explore the dynamic world of the nucleus at the new EMBO | EMBL Symposium. From nuclear mechanics to pathomechanisms, join the conversation shaping modern cell biology.
🗓️ 18 – 21 November 2025
📥 Submit your abstract by 26 August
👉 https://s.embl.org/ees25-07-bl
Explore the dynamic world of the nucleus at the new EMBO | EMBL Symposium. From nuclear mechanics to pathomechanisms, join the conversation shaping modern cell biology.
🗓️ 18 – 21 November 2025
📥 Submit your abstract by 26 August
👉 https://s.embl.org/ees25-07-bl
January 24, 2025 at 12:11 PM
Interested in the cell biology of the nucleus? Join us for this unique exciting meeting that covers everything from nuclear biophysics and mechanics to signaling and evolution😍 amazing speaker list and more will be selected from abstracts 🤩
Super - congrats Thomas! Very proud to have you as colleague at IBDM 😀
Had a fantastic time at the Fertility Conference 2025 in Liverpool! And thrilled to have been awarded the British Fertility Society Best Young Scientist Award! 🙌🏼
January 12, 2025 at 5:40 PM
Super - congrats Thomas! Very proud to have you as colleague at IBDM 😀
Reposted by Frank Schnorrer
Together with other JEDIs @michaelrera.bsky.social @drosostalis.bsky.social @ksiudeja.bsky.social @felsenberg.bsky.social and Gerit Linneweber, we are trying to restart this awesome initiative that was unfortunately silenced during COVID. More information here: flies-jedi.github.io Please repost!
January 10, 2025 at 1:49 PM
Together with other JEDIs @michaelrera.bsky.social @drosostalis.bsky.social @ksiudeja.bsky.social @felsenberg.bsky.social and Gerit Linneweber, we are trying to restart this awesome initiative that was unfortunately silenced during COVID. More information here: flies-jedi.github.io Please repost!
Reposted by Frank Schnorrer
We are excited to announce the opening of registrations for the upcoming #EDRC2025 conference (25th-28th September 2025) in Alicante to showcase the latest advances in #Drosophila biology and technology edrc2025alicante.com
EDRC 2025 Alicante
edrc2025alicante.com
January 7, 2025 at 2:29 PM
We are excited to announce the opening of registrations for the upcoming #EDRC2025 conference (25th-28th September 2025) in Alicante to showcase the latest advances in #Drosophila biology and technology edrc2025alicante.com
Reposted by Frank Schnorrer
Interesting study showing that Bicoid clusters in fly embryos preserve nuclear concentration info, guiding gene expression despite non-linear LLPS models. These clusters also act as high-fidelity sensors, key for fast, precise transcriptional regulation. www.science.org/doi/10.1126/...
Transcription factor clusters as information transfer agents
Live imaging shows that regulatory protein clusters may aid fast and precise delivery of transcriptional information to gene loci.
www.science.org
January 6, 2025 at 4:01 PM
Interesting study showing that Bicoid clusters in fly embryos preserve nuclear concentration info, guiding gene expression despite non-linear LLPS models. These clusters also act as high-fidelity sensors, key for fast, precise transcriptional regulation. www.science.org/doi/10.1126/...
Reposted by Frank Schnorrer
Interested in starting a PhD to explore ovarian biology through a cross-disciplinary approach combining live-cell microscopy and biophysics?
Get in touch for more details—and please share! 🔬🙌🏼
Get in touch for more details—and please share! 🔬🙌🏼
January 2, 2025 at 12:00 PM
Interested in starting a PhD to explore ovarian biology through a cross-disciplinary approach combining live-cell microscopy and biophysics?
Get in touch for more details—and please share! 🔬🙌🏼
Get in touch for more details—and please share! 🔬🙌🏼
mitoXplorer goes single cell data - how similar are mitochondria between individual cells? Test it in your data.
New year, new version of mitoXplorer 3.0 (mitoxplorer3.ibdm.univ-amu.fr) : mine your single-cell RNA-seq data from a mitochondrial perspective by creating cell-type specific pseudo-bulks or by looking at mitochondrial variability on single-cell level. Check it out at doi: doi.org/10.1101/2024...
mitoXplorer 3.0, a web tool for exploring mitochondrial dynamics in single-cell RNA-seq data
Mitochondria are important eukaryotic organelles, best known for their function in ATP production and in cellular metabolism and signalling. It is widely accepted that their structure, composition and...
doi.org
January 2, 2025 at 4:00 PM
mitoXplorer goes single cell data - how similar are mitochondria between individual cells? Test it in your data.
Muscles growth by sarcomere divisions - how your muscles add new sarcomeres during developmental growth: they divide! Cool collaboration @friedrich-group.bsky.social @raunser-lab.bsky.social @Dirk Görlich @univ-amu.fr @cnrs.bsky.social sciencecast.org/casts/aspy9l... www.biorxiv.org/content/10.1...
December 19, 2024 at 10:10 AM
Muscles growth by sarcomere divisions - how your muscles add new sarcomeres during developmental growth: they divide! Cool collaboration @friedrich-group.bsky.social @raunser-lab.bsky.social @Dirk Görlich @univ-amu.fr @cnrs.bsky.social sciencecast.org/casts/aspy9l... www.biorxiv.org/content/10.1...