Joe McKellar
@viroscope.bsky.social
SciArt & Scientific Visualization (PhD) | Creating Blockbuster Visuals for R&D, Marketing & Advertising
The Big Crunch.
The Big Bang.
And the expansion that follows.
Not a simulation of the early universe, but a single A549 cell dividing.
Watch the Rab11a endosomes rush like a supply fleet. One life becoming two.
Cosmology on a cellular scale.
#SciArt #Microscopy #Fluorescencefriday #BigBang
The Big Bang.
And the expansion that follows.
Not a simulation of the early universe, but a single A549 cell dividing.
Watch the Rab11a endosomes rush like a supply fleet. One life becoming two.
Cosmology on a cellular scale.
#SciArt #Microscopy #Fluorescencefriday #BigBang
January 8, 2026 at 11:37 PM
The Big Crunch.
The Big Bang.
And the expansion that follows.
Not a simulation of the early universe, but a single A549 cell dividing.
Watch the Rab11a endosomes rush like a supply fleet. One life becoming two.
Cosmology on a cellular scale.
#SciArt #Microscopy #Fluorescencefriday #BigBang
The Big Bang.
And the expansion that follows.
Not a simulation of the early universe, but a single A549 cell dividing.
Watch the Rab11a endosomes rush like a supply fleet. One life becoming two.
Cosmology on a cellular scale.
#SciArt #Microscopy #Fluorescencefriday #BigBang
At first glance, chaos.
Looking closer at this human fibroblast however, angles, parallels, and geometric stars appear.
Order in biology is often disguised as chaos. Beautiful chaos.
A golden web spun from the fabric of life.
💛 Gold: Actin
🩵 Cyan: Septin 7
🩶 Grey: DNA
#SciArt #Microscopy
Looking closer at this human fibroblast however, angles, parallels, and geometric stars appear.
Order in biology is often disguised as chaos. Beautiful chaos.
A golden web spun from the fabric of life.
💛 Gold: Actin
🩵 Cyan: Septin 7
🩶 Grey: DNA
#SciArt #Microscopy
January 7, 2026 at 8:30 AM
At first glance, chaos.
Looking closer at this human fibroblast however, angles, parallels, and geometric stars appear.
Order in biology is often disguised as chaos. Beautiful chaos.
A golden web spun from the fabric of life.
💛 Gold: Actin
🩵 Cyan: Septin 7
🩶 Grey: DNA
#SciArt #Microscopy
Looking closer at this human fibroblast however, angles, parallels, and geometric stars appear.
Order in biology is often disguised as chaos. Beautiful chaos.
A golden web spun from the fabric of life.
💛 Gold: Actin
🩵 Cyan: Septin 7
🩶 Grey: DNA
#SciArt #Microscopy
Reposted by Joe McKellar
@viroscope.bsky.social (@karimaj.bsky.social team) partage dans The Scientist ses travaux sur les deltavirus et l’imagerie de cellules, des cellules humaines aux cellules de boa constrictor 🐍.
👉 Lire l’article : “Boa Constrictor Brain Cells Slither into Focus”
www.the-scientist.com/boa-constric...
👉 Lire l’article : “Boa Constrictor Brain Cells Slither into Focus”
www.the-scientist.com/boa-constric...
Boa Constrictor Brain Cells Slither into Focus
From reptiles and Tasmanian devils to humans, one researcher zooms in on unseen features of the brain and liver cells, like the cytoskeleton.
www.the-scientist.com
October 13, 2025 at 11:13 AM
@viroscope.bsky.social (@karimaj.bsky.social team) partage dans The Scientist ses travaux sur les deltavirus et l’imagerie de cellules, des cellules humaines aux cellules de boa constrictor 🐍.
👉 Lire l’article : “Boa Constrictor Brain Cells Slither into Focus”
www.the-scientist.com/boa-constric...
👉 Lire l’article : “Boa Constrictor Brain Cells Slither into Focus”
www.the-scientist.com/boa-constric...
Go and vote for @dianabrychka.bsky.social's stunning image of a brain organoid ! 🤩
My little brain organoid is in a contest. If you find it pretty, you can vote for it 🤍
Go look at the other images too, they’re stunning!
Here is the link to vote:
m.cmpgn.page/jxZjTb?sre=2...
#MicroscopyMonday #SciArt
Go look at the other images too, they’re stunning!
Here is the link to vote:
m.cmpgn.page/jxZjTb?sre=2...
#MicroscopyMonday #SciArt
June 30, 2025 at 1:14 PM
Go and vote for @dianabrychka.bsky.social's stunning image of a brain organoid ! 🤩
A Boa Constrictor brain-derived cell expressing a viral glycoprotein (magenta) and stained for actin (yellow) and DNA (white).
#FluorescenceFriday
#FluorescenceFriday
June 27, 2025 at 11:20 AM
A Boa Constrictor brain-derived cell expressing a viral glycoprotein (magenta) and stained for actin (yellow) and DNA (white).
#FluorescenceFriday
#FluorescenceFriday
HFF cells stained for DNA ⚪, intermediate filaments 🟠, microtubules 🔴 and actin 🔵.
#FluorescenceFriday
#SciArt
#FluorescenceFriday
#SciArt
May 30, 2025 at 2:18 PM
HFF cells stained for DNA ⚪, intermediate filaments 🟠, microtubules 🔴 and actin 🔵.
#FluorescenceFriday
#SciArt
#FluorescenceFriday
#SciArt
For #FluorescenceFriday, a field of individual VSV (rod-shaped, in 🟧) and Deltavirus (dot-shaped, in 🔵) particles imaged by STED (20nm per pixel).
We now know that Deltaviruses can package inside particles of other viruses.
Can you find any of these dual particles in this field?
We now know that Deltaviruses can package inside particles of other viruses.
Can you find any of these dual particles in this field?
May 23, 2025 at 12:05 PM
For #FluorescenceFriday, a field of individual VSV (rod-shaped, in 🟧) and Deltavirus (dot-shaped, in 🔵) particles imaged by STED (20nm per pixel).
We now know that Deltaviruses can package inside particles of other viruses.
Can you find any of these dual particles in this field?
We now know that Deltaviruses can package inside particles of other viruses.
Can you find any of these dual particles in this field?
Reposted by Joe McKellar
🔬✨ Today for #FluorescenceFriday:
A close-up of the dorsal part of the first gill arch in a mature zebrafish.
The intricate vascular network supporting respiration, visualized using kdrl:mcherry.
#Zebrafish #DevBio #Microscopy #Fluorescence #SciArt
A close-up of the dorsal part of the first gill arch in a mature zebrafish.
The intricate vascular network supporting respiration, visualized using kdrl:mcherry.
#Zebrafish #DevBio #Microscopy #Fluorescence #SciArt
May 16, 2025 at 1:38 PM
🔬✨ Today for #FluorescenceFriday:
A close-up of the dorsal part of the first gill arch in a mature zebrafish.
The intricate vascular network supporting respiration, visualized using kdrl:mcherry.
#Zebrafish #DevBio #Microscopy #Fluorescence #SciArt
A close-up of the dorsal part of the first gill arch in a mature zebrafish.
The intricate vascular network supporting respiration, visualized using kdrl:mcherry.
#Zebrafish #DevBio #Microscopy #Fluorescence #SciArt
Viruses in the forest of the lungs.
Human airway epithelia stained for actin 🟢 and SARS-CoV-2 RNA 🟣.
#FluorescenceFriday
#SciArt
Human airway epithelia stained for actin 🟢 and SARS-CoV-2 RNA 🟣.
#FluorescenceFriday
#SciArt
May 16, 2025 at 11:01 AM
Viruses in the forest of the lungs.
Human airway epithelia stained for actin 🟢 and SARS-CoV-2 RNA 🟣.
#FluorescenceFriday
#SciArt
Human airway epithelia stained for actin 🟢 and SARS-CoV-2 RNA 🟣.
#FluorescenceFriday
#SciArt
Reposted by Joe McKellar
Saw this presented at ECV 2025. Fanastic and thought provoking work! Congrats to @viroscope.bsky.social, @karimaj.bsky.social and coauthors.
⚠️ Discovery of a new mode of viral transmission:
Deltaviruses spread through a viral Trojan Horse !
These viral satellites that do not encode their own glycoproteins, are in fact physically encapsulated within their helper virus particles!
www.biorxiv.org/content/10.1...
A thread 1/14
Deltaviruses spread through a viral Trojan Horse !
These viral satellites that do not encode their own glycoproteins, are in fact physically encapsulated within their helper virus particles!
www.biorxiv.org/content/10.1...
A thread 1/14
May 10, 2025 at 10:45 AM
Saw this presented at ECV 2025. Fanastic and thought provoking work! Congrats to @viroscope.bsky.social, @karimaj.bsky.social and coauthors.
Reposted by Joe McKellar
Deltaviruses spread through a viral Trojan Horse www.biorxiv.org/content/10.1...
Deltaviruses spread through a viral Trojan Horse
Hepatitis D-like viral satellites, known as deltaviruses, have been recently discovered in a wide range of animals. These viruses are thought to expropriate glycoproteins from helper viruses to form i...
www.biorxiv.org
May 12, 2025 at 12:52 PM
Deltaviruses spread through a viral Trojan Horse www.biorxiv.org/content/10.1...
Reposted by Joe McKellar
Deltaviruses spread through a viral Trojan Horse https://www.biorxiv.org/content/10.1101/2025.05.09.653040v1
May 10, 2025 at 3:17 AM
Deltaviruses spread through a viral Trojan Horse https://www.biorxiv.org/content/10.1101/2025.05.09.653040v1
Reposted by Joe McKellar
Deltaviruses spread through a viral Trojan Horse https://www.biorxiv.org/content/10.1101/2025.05.09.653040v1
May 10, 2025 at 3:17 AM
Deltaviruses spread through a viral Trojan Horse https://www.biorxiv.org/content/10.1101/2025.05.09.653040v1
Reposted by Joe McKellar
With Joe in our lab, we discovered a new mode of how some viral sattelites can spread : A form of viral hitchhiking we termed Viral Trojan Horse ! check our paper on biorXiv : www.biorxiv.org/content/10.1...
⚠️ Discovery of a new mode of viral transmission:
Deltaviruses spread through a viral Trojan Horse !
These viral satellites that do not encode their own glycoproteins, are in fact physically encapsulated within their helper virus particles!
www.biorxiv.org/content/10.1...
A thread 1/14
Deltaviruses spread through a viral Trojan Horse !
These viral satellites that do not encode their own glycoproteins, are in fact physically encapsulated within their helper virus particles!
www.biorxiv.org/content/10.1...
A thread 1/14
May 10, 2025 at 8:20 AM
With Joe in our lab, we discovered a new mode of how some viral sattelites can spread : A form of viral hitchhiking we termed Viral Trojan Horse ! check our paper on biorXiv : www.biorxiv.org/content/10.1...
⚠️ Discovery of a new mode of viral transmission:
Deltaviruses spread through a viral Trojan Horse !
These viral satellites that do not encode their own glycoproteins, are in fact physically encapsulated within their helper virus particles!
www.biorxiv.org/content/10.1...
A thread 1/14
Deltaviruses spread through a viral Trojan Horse !
These viral satellites that do not encode their own glycoproteins, are in fact physically encapsulated within their helper virus particles!
www.biorxiv.org/content/10.1...
A thread 1/14
May 10, 2025 at 8:12 AM
⚠️ Discovery of a new mode of viral transmission:
Deltaviruses spread through a viral Trojan Horse !
These viral satellites that do not encode their own glycoproteins, are in fact physically encapsulated within their helper virus particles!
www.biorxiv.org/content/10.1...
A thread 1/14
Deltaviruses spread through a viral Trojan Horse !
These viral satellites that do not encode their own glycoproteins, are in fact physically encapsulated within their helper virus particles!
www.biorxiv.org/content/10.1...
A thread 1/14
The beauty and chaos of structure.
HFF cells stained for cytoskeletal proteins Actin (⚪), Septin (🟡), Tubulin (🟣) and DNA (🔵).
#FluorescenceFriday
#SciArt
HFF cells stained for cytoskeletal proteins Actin (⚪), Septin (🟡), Tubulin (🟣) and DNA (🔵).
#FluorescenceFriday
#SciArt
May 9, 2025 at 3:25 PM
The beauty and chaos of structure.
HFF cells stained for cytoskeletal proteins Actin (⚪), Septin (🟡), Tubulin (🟣) and DNA (🔵).
#FluorescenceFriday
#SciArt
HFF cells stained for cytoskeletal proteins Actin (⚪), Septin (🟡), Tubulin (🟣) and DNA (🔵).
#FluorescenceFriday
#SciArt
Reposted by Joe McKellar
#ECV #ECV2025 very proud of @viroscope.bsky.social that presented brilliantly his work in our lab “Deltaviruses spread through viral Trojan Horse” at the European Congress of Virology 2025 in Cavtat, Croatia !
April 28, 2025 at 1:24 PM
#ECV #ECV2025 very proud of @viroscope.bsky.social that presented brilliantly his work in our lab “Deltaviruses spread through viral Trojan Horse” at the European Congress of Virology 2025 in Cavtat, Croatia !
A culture of boa constrictor cells expressing a fusogenic viral protein, leading to cell fusion and giant multinucleated cells!
Actin is in gold, membranes in white and DNA in blue.
#FluorescenceFriday #SciArt
Actin is in gold, membranes in white and DNA in blue.
#FluorescenceFriday #SciArt
April 11, 2025 at 11:23 AM
A culture of boa constrictor cells expressing a fusogenic viral protein, leading to cell fusion and giant multinucleated cells!
Actin is in gold, membranes in white and DNA in blue.
#FluorescenceFriday #SciArt
Actin is in gold, membranes in white and DNA in blue.
#FluorescenceFriday #SciArt
Reposted by Joe McKellar
My monocyte, with a fluorescent membrane (EGFP-CAAX 💛), is transmigrating across the brain microvascular endothelium (VE-cadherin 💙)
#FluorescenceFriday #SciArt
#FluorescenceFriday #SciArt
April 4, 2025 at 1:54 PM
My monocyte, with a fluorescent membrane (EGFP-CAAX 💛), is transmigrating across the brain microvascular endothelium (VE-cadherin 💙)
#FluorescenceFriday #SciArt
#FluorescenceFriday #SciArt
A human lung cell expressing the antiviral protein MX1.
Actin is in cyan, MX1 in orange and DNA in yellow.
#FluorescenceFriday #SciArt
Actin is in cyan, MX1 in orange and DNA in yellow.
#FluorescenceFriday #SciArt
April 4, 2025 at 5:27 PM
A human lung cell expressing the antiviral protein MX1.
Actin is in cyan, MX1 in orange and DNA in yellow.
#FluorescenceFriday #SciArt
Actin is in cyan, MX1 in orange and DNA in yellow.
#FluorescenceFriday #SciArt
Reposted by Joe McKellar
March 28, 2025 at 4:02 PM
Micro-rearrangement of DNA and proteins is a highly dynamic process!
As shown here with cell nucleus (DNA in gray) expressing a fluorescent protein (orange).
1 image acquired every 2 seconds for 2 minutes.
#FluorescenceFriday
#SciArt
As shown here with cell nucleus (DNA in gray) expressing a fluorescent protein (orange).
1 image acquired every 2 seconds for 2 minutes.
#FluorescenceFriday
#SciArt
March 28, 2025 at 2:59 PM
Micro-rearrangement of DNA and proteins is a highly dynamic process!
As shown here with cell nucleus (DNA in gray) expressing a fluorescent protein (orange).
1 image acquired every 2 seconds for 2 minutes.
#FluorescenceFriday
#SciArt
As shown here with cell nucleus (DNA in gray) expressing a fluorescent protein (orange).
1 image acquired every 2 seconds for 2 minutes.
#FluorescenceFriday
#SciArt
New cell line = New cell morphologies to explore!
This hepatic cell line has fully invested into membrane protrusions!
Actin is shown in 🟦 and DNA in 🟧
#FluorescenceFriday
#SciArt
This hepatic cell line has fully invested into membrane protrusions!
Actin is shown in 🟦 and DNA in 🟧
#FluorescenceFriday
#SciArt
March 21, 2025 at 1:05 PM
New cell line = New cell morphologies to explore!
This hepatic cell line has fully invested into membrane protrusions!
Actin is shown in 🟦 and DNA in 🟧
#FluorescenceFriday
#SciArt
This hepatic cell line has fully invested into membrane protrusions!
Actin is shown in 🟦 and DNA in 🟧
#FluorescenceFriday
#SciArt
Reposted by Joe McKellar
One of my favourite images: monocytes 💙 infiltrating a little brain organoid, with post-synaptic protein PSD95 ❤️ and nuclei 🤍 visualized
#FluorescenceFriday
#SciArt
#FluorescenceFriday
#SciArt
March 14, 2025 at 8:16 PM
One of my favourite images: monocytes 💙 infiltrating a little brain organoid, with post-synaptic protein PSD95 ❤️ and nuclei 🤍 visualized
#FluorescenceFriday
#SciArt
#FluorescenceFriday
#SciArt
A Spiky Cell
A boa constrictor brain-derived cell stained for membranes (cyan), actin (yellow) and DNA (pink)
#FluorescenceFriday
#SciArt
A boa constrictor brain-derived cell stained for membranes (cyan), actin (yellow) and DNA (pink)
#FluorescenceFriday
#SciArt
March 7, 2025 at 2:09 PM
A Spiky Cell
A boa constrictor brain-derived cell stained for membranes (cyan), actin (yellow) and DNA (pink)
#FluorescenceFriday
#SciArt
A boa constrictor brain-derived cell stained for membranes (cyan), actin (yellow) and DNA (pink)
#FluorescenceFriday
#SciArt