The shift strong-arms doctors but hasn’t saved money or shortened waits for critical operations, sources say. A Tyee investigation.

Ativistas denunciam que a presença de representantes da indústria de combustíveis fósseis enfraquece as negociações climáticas e afasta a conferência de avanços reais.

Alberta is working on plans to treat and release oilsands wastewater into the Athabasca River. First Nations downstream don’t want that to happen

Background: All of the major antigenic changes in influenza A(H3N2) viruses since 1968 have involved mutations at just nine amino acid positions, called cluster transition sites, surrounding the receptor binding region of the hemagglutinin surface protein. During the northern hemisphere (NH) 2024–2025 influenza season, A(H3N2) variants emerged with multiple parallel substitutions affecting cluster transition sites 135, 145, 158 and/or 189, with implications for the 2025–2026 season. Methods: Using >24,000 global A(H3) sequences between September 2024 and August 2025, we assess the nature and frequency of amino acid mutations among emerging NH and southern hemisphere (SH) A(H3N2) variants relative to the 2024–2025 subclade J and updated 2025–2026 subclade J.2 vaccine reference strains. We contextualize based upon historic amino acid variation among >210,000 global A(H3) sequences since 1968 and publicly available antigenic characterization data relative to 2024–2025 and 2025–2026 vaccine reference strains Results: Virtually all circulating A(H3N2) viruses in 2024–2025 were subclade J.2. In Europe, about one-third had cluster transition site mutations, mostly T135A with S145N. In North America, more than two-thirds had cluster transition site mutations, including T135K or S145N, with late-season increase in doubly mutated J.2.3 (N158K + K189R) and J.2.5 (S145N + N158K) subclades. The SH 2025 season showed increase in J.2.3 and emergence of J.2.4 (T135K + K189R) including a further drifted J.2.4.1 variant with additional N158D and other mutations, recently renamed subclade K. A substantial proportion of J.2.3 and J.2.4 viruses are antigenically distinct from the 2025–2026 influenza vaccine. Conclusion: Influenza A(H3N2) variants with a combination of cluster transition site mutations emerged during the NH 2024–2025 season. A further drifted and vaccine-mismatched variant now called subclade K arose during the SH 2025 season and is projected to predominate among A(H3N2) viruses for the NH 2025–2026 season. While mismatched vaccines may still provide protection, enhanced genetic, antigenic and epidemiological (eg, vaccine effectiveness) monitoring are warranted to inform risk assessment and response.

Some scientists say this year's flu shot isn't well matched to a key strain that could spread widely in the months ahead. So, is there still a point in getting it? Medical experts say: absolutely. Her...

A municipality in northwest Alberta plans to put forward a resolution at the Rural Municipalities of Alberta Convention calling on Ottawa to legalize the on-farm sale of raw, unpasteurized dairy produ...

Armed conflict is rising, and Canada plans to increase military spending. Peace advocates say that social programs, not militarization, make a safer world. Even military generals in Canada and the Uni...

Plans to alter what Alberta driver’s licences and ID cards tell authorities need a rethink.

Insolvencies are up sharply, and there’s growing evidence that gambling is partly to blame

The shift strong-arms doctors but hasn’t saved money or shortened waits for critical operations, sources say. A Tyee investigation.

YouTube video by Energi Media

The latest federal data shows Alberta accounts for 38 per cent of Canada’s cases.

Dozens of Calgarians gathered Wednesday to call on the province to step up environmental protections and take proper action to address the growing costs of abandoned oil and gas wells.

On Nov 5, 185 Calgarians packed the Royal Canadian Legion to send a clear message to the government: we won’t let oil companies walk away from billions in cleanup costs AND we won’t accept new coal mi...

After lobbyists spent big on the Trump administration and Democratic defectors, the government funding bill cut food-contamination rules and limited ultraprocessed-food research.