Alexandra Colin
@alexandra-colin.bsky.social
CNRS researcher in the Cytomorpholab (Grenoble, France)
Reposted by Alexandra Colin
⚡Ready to grow and be inspired as a scientist?
We’re looking for a *PhD student* to join our lab at @crg.eu
in Barcelona and explore how cells self-organize, uncovering life’s inner design💡
We offer strong mentoring, cutting-edge science, and a vibrant international team🌍
Check the link below!
We’re looking for a *PhD student* to join our lab at @crg.eu
in Barcelona and explore how cells self-organize, uncovering life’s inner design💡
We offer strong mentoring, cutting-edge science, and a vibrant international team🌍
Check the link below!
October 23, 2025 at 9:56 AM
⚡Ready to grow and be inspired as a scientist?
We’re looking for a *PhD student* to join our lab at @crg.eu
in Barcelona and explore how cells self-organize, uncovering life’s inner design💡
We offer strong mentoring, cutting-edge science, and a vibrant international team🌍
Check the link below!
We’re looking for a *PhD student* to join our lab at @crg.eu
in Barcelona and explore how cells self-organize, uncovering life’s inner design💡
We offer strong mentoring, cutting-edge science, and a vibrant international team🌍
Check the link below!
Reposted by Alexandra Colin
Very excited that my final postdoctoral work is now online in Cell @cellpress.bsky.social.
www.sciencedirect.com/science/arti...
Using 16 (!) cryo-EM structures, we uncovered how the three proteins coronin, cofilin and AIP1 work together to rapidly disassemble actin filaments.
www.sciencedirect.com/science/arti...
Using 16 (!) cryo-EM structures, we uncovered how the three proteins coronin, cofilin and AIP1 work together to rapidly disassemble actin filaments.
October 13, 2025 at 9:04 AM
Very excited that my final postdoctoral work is now online in Cell @cellpress.bsky.social.
www.sciencedirect.com/science/arti...
Using 16 (!) cryo-EM structures, we uncovered how the three proteins coronin, cofilin and AIP1 work together to rapidly disassemble actin filaments.
www.sciencedirect.com/science/arti...
Using 16 (!) cryo-EM structures, we uncovered how the three proteins coronin, cofilin and AIP1 work together to rapidly disassemble actin filaments.
Reposted by Alexandra Colin
Live on Oct 7, the MBoC 2025 Early Career Award Webinar (Part 1) runs 12–1 pm ET.
> Keynote: Margaret Gardel (UChicago)
> lightning talks from UCSF, UVM, ETH Zurich, Cambridge & Harvard
> moderation by John Aitchison
Free to attend → www.ascb.org/ascb-meeting... #ASCB #CellBiology
> Keynote: Margaret Gardel (UChicago)
> lightning talks from UCSF, UVM, ETH Zurich, Cambridge & Harvard
> moderation by John Aitchison
Free to attend → www.ascb.org/ascb-meeting... #ASCB #CellBiology
September 24, 2025 at 12:29 PM
Live on Oct 7, the MBoC 2025 Early Career Award Webinar (Part 1) runs 12–1 pm ET.
> Keynote: Margaret Gardel (UChicago)
> lightning talks from UCSF, UVM, ETH Zurich, Cambridge & Harvard
> moderation by John Aitchison
Free to attend → www.ascb.org/ascb-meeting... #ASCB #CellBiology
> Keynote: Margaret Gardel (UChicago)
> lightning talks from UCSF, UVM, ETH Zurich, Cambridge & Harvard
> moderation by John Aitchison
Free to attend → www.ascb.org/ascb-meeting... #ASCB #CellBiology
Reposted by Alexandra Colin
”Please inhibit responsibly: Natural and synthetic actin toxins as useful tools in cell biology”
I had a lot of fun going down different actin inhibitor rabbit holes with @onishilab.bsky.social on this perspective!
www.molbiolcell.org/doi/10.1091/...
www.molbiolcell.org/cms/10.1091/...
I had a lot of fun going down different actin inhibitor rabbit holes with @onishilab.bsky.social on this perspective!
www.molbiolcell.org/doi/10.1091/...
www.molbiolcell.org/cms/10.1091/...
September 16, 2025 at 1:31 AM
”Please inhibit responsibly: Natural and synthetic actin toxins as useful tools in cell biology”
I had a lot of fun going down different actin inhibitor rabbit holes with @onishilab.bsky.social on this perspective!
www.molbiolcell.org/doi/10.1091/...
www.molbiolcell.org/cms/10.1091/...
I had a lot of fun going down different actin inhibitor rabbit holes with @onishilab.bsky.social on this perspective!
www.molbiolcell.org/doi/10.1091/...
www.molbiolcell.org/cms/10.1091/...
Reposted by Alexandra Colin
We’re organizing a conference at @ijmonod.bsky.social in Paris, January 2026, in memory of M.P. Sheetz — pioneer in cell mechanics and mechanobiology, co-discoverer of kinesin, and founder of @mbisg.bsky.social. Join us to explore his legacy.
mikeinmemoriam.sciencesconf.org
mikeinmemoriam.sciencesconf.org
September 18, 2025 at 8:50 AM
We’re organizing a conference at @ijmonod.bsky.social in Paris, January 2026, in memory of M.P. Sheetz — pioneer in cell mechanics and mechanobiology, co-discoverer of kinesin, and founder of @mbisg.bsky.social. Join us to explore his legacy.
mikeinmemoriam.sciencesconf.org
mikeinmemoriam.sciencesconf.org
Reposted by Alexandra Colin
Allocation of resources among multiple daughter cells. New study from Alison Wirshing, Daniel Lew and colleagues @mit.edu: rupress.org/jcb/article/...
#Cytoskeleton #Development
#Cytoskeleton #Development
September 9, 2025 at 2:16 PM
Allocation of resources among multiple daughter cells. New study from Alison Wirshing, Daniel Lew and colleagues @mit.edu: rupress.org/jcb/article/...
#Cytoskeleton #Development
#Cytoskeleton #Development
Reposted by Alexandra Colin
New short paper from our lab @currentbiology.bsky.social, in which we discover of a new mode of cell motility for choanoflagellates: flagellar gliding. www.cell.com/current-biol... - A 🧵
Flagellar gliding in choanoflagellates
Freire-Delgado and Brunet discover a new mode of cell motility in choanoflagellates,
the closest relatives of animals. Under mild confinement, choanoflagellate move over
surfaces without cell deformat...
www.cell.com
September 9, 2025 at 6:12 PM
New short paper from our lab @currentbiology.bsky.social, in which we discover of a new mode of cell motility for choanoflagellates: flagellar gliding. www.cell.com/current-biol... - A 🧵
Reposted by Alexandra Colin
Which city is the best for Cytoskeleton research?
Dresden? Barcelona? Cambridge ? Noooo ... you all know its Paris, right? 😎
Registering to the annual meeting on Friday 14th of November is now open:
pcd2025.sciencesconf.org
Keynote speeches by @carter-lab.bsky.social and Verena Ruprecht !
Dresden? Barcelona? Cambridge ? Noooo ... you all know its Paris, right? 😎
Registering to the annual meeting on Friday 14th of November is now open:
pcd2025.sciencesconf.org
Keynote speeches by @carter-lab.bsky.social and Verena Ruprecht !
Paris Cytoskeleton Day 2025 - Sciencesconf.org
pcd2025.sciencesconf.org
September 9, 2025 at 12:32 PM
Which city is the best for Cytoskeleton research?
Dresden? Barcelona? Cambridge ? Noooo ... you all know its Paris, right? 😎
Registering to the annual meeting on Friday 14th of November is now open:
pcd2025.sciencesconf.org
Keynote speeches by @carter-lab.bsky.social and Verena Ruprecht !
Dresden? Barcelona? Cambridge ? Noooo ... you all know its Paris, right? 😎
Registering to the annual meeting on Friday 14th of November is now open:
pcd2025.sciencesconf.org
Keynote speeches by @carter-lab.bsky.social and Verena Ruprecht !
Reposted by Alexandra Colin
A new #UExM probe for #Actin!
Fun times thinking/developing/testing with @centriolelab.bsky.social & @lreymond.bsky.social !
Congrats to all !
If interested in #UExM, or #HAK-Actin, feel free to reach out !
Soon available at @spirochrome.com
#Expansion #Microscopy #ProtistsOnSky
Fun times thinking/developing/testing with @centriolelab.bsky.social & @lreymond.bsky.social !
Congrats to all !
If interested in #UExM, or #HAK-Actin, feel free to reach out !
Soon available at @spirochrome.com
#Expansion #Microscopy #ProtistsOnSky
Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1...
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
August 28, 2025 at 7:16 AM
A new #UExM probe for #Actin!
Fun times thinking/developing/testing with @centriolelab.bsky.social & @lreymond.bsky.social !
Congrats to all !
If interested in #UExM, or #HAK-Actin, feel free to reach out !
Soon available at @spirochrome.com
#Expansion #Microscopy #ProtistsOnSky
Fun times thinking/developing/testing with @centriolelab.bsky.social & @lreymond.bsky.social !
Congrats to all !
If interested in #UExM, or #HAK-Actin, feel free to reach out !
Soon available at @spirochrome.com
#Expansion #Microscopy #ProtistsOnSky
Reposted by Alexandra Colin
🌱✂️ How do plant cells decide where to divide?
Our work shows that actin can override the geometric rules—guiding cells to divide in alternative orientations.
#PlantScience #CellBiology #Arabidopsis
@camilagoldy.bsky.social @rdplab.bsky.social
www.biorxiv.org/content/10.1...
Our work shows that actin can override the geometric rules—guiding cells to divide in alternative orientations.
#PlantScience #CellBiology #Arabidopsis
@camilagoldy.bsky.social @rdplab.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org
August 25, 2025 at 8:34 AM
🌱✂️ How do plant cells decide where to divide?
Our work shows that actin can override the geometric rules—guiding cells to divide in alternative orientations.
#PlantScience #CellBiology #Arabidopsis
@camilagoldy.bsky.social @rdplab.bsky.social
www.biorxiv.org/content/10.1...
Our work shows that actin can override the geometric rules—guiding cells to divide in alternative orientations.
#PlantScience #CellBiology #Arabidopsis
@camilagoldy.bsky.social @rdplab.bsky.social
www.biorxiv.org/content/10.1...
Reposted by Alexandra Colin
Microtubules: the architect of muscles. Watch how microtubules transport mitochondria in proximity to energy consuming sarcomeres in muscles of flies and mice. @jeromeavellaneda.bsky.social @nunoluis.bsky.social @ibdm.bsky.social with @gomeslabo.bsky.social www.sciencedirect.com/science/arti...
July 21, 2025 at 12:52 PM
Microtubules: the architect of muscles. Watch how microtubules transport mitochondria in proximity to energy consuming sarcomeres in muscles of flies and mice. @jeromeavellaneda.bsky.social @nunoluis.bsky.social @ibdm.bsky.social with @gomeslabo.bsky.social www.sciencedirect.com/science/arti...
Reposted by Alexandra Colin
We have used many microwells to confine biochemical reactions in our recent studies. We wanted to share the protocol for preparing and characterizing microwells; this protocol is now published here : www.frontiersin.org/journals/cel...
@manuelthery.bsky.social @lblanchoin.bsky.social
@manuelthery.bsky.social @lblanchoin.bsky.social
July 17, 2025 at 7:20 AM
We have used many microwells to confine biochemical reactions in our recent studies. We wanted to share the protocol for preparing and characterizing microwells; this protocol is now published here : www.frontiersin.org/journals/cel...
@manuelthery.bsky.social @lblanchoin.bsky.social
@manuelthery.bsky.social @lblanchoin.bsky.social
Reposted by Alexandra Colin
#science 🧬 | Non, ce ne sont ni les slips de Superman, ni ceux de Walter White dans Breaking Bad.
C’est une cellule ... et la même photographiée 36 fois.
Sensation, adaptation, mémoire… la cellule est plus futée qu’on ne le croit 🤯.
Pour en savoir plus 👉 youtu.be/dX4rDXLJAdI
C’est une cellule ... et la même photographiée 36 fois.
Sensation, adaptation, mémoire… la cellule est plus futée qu’on ne le croit 🤯.
Pour en savoir plus 👉 youtu.be/dX4rDXLJAdI
July 18, 2025 at 7:17 AM
#science 🧬 | Non, ce ne sont ni les slips de Superman, ni ceux de Walter White dans Breaking Bad.
C’est une cellule ... et la même photographiée 36 fois.
Sensation, adaptation, mémoire… la cellule est plus futée qu’on ne le croit 🤯.
Pour en savoir plus 👉 youtu.be/dX4rDXLJAdI
C’est une cellule ... et la même photographiée 36 fois.
Sensation, adaptation, mémoire… la cellule est plus futée qu’on ne le croit 🤯.
Pour en savoir plus 👉 youtu.be/dX4rDXLJAdI
We have used many microwells to confine biochemical reactions in our recent studies. We wanted to share the protocol for preparing and characterizing microwells; this protocol is now published here : www.frontiersin.org/journals/cel...
@manuelthery.bsky.social @lblanchoin.bsky.social
@manuelthery.bsky.social @lblanchoin.bsky.social
July 17, 2025 at 7:20 AM
We have used many microwells to confine biochemical reactions in our recent studies. We wanted to share the protocol for preparing and characterizing microwells; this protocol is now published here : www.frontiersin.org/journals/cel...
@manuelthery.bsky.social @lblanchoin.bsky.social
@manuelthery.bsky.social @lblanchoin.bsky.social
Reposted by Alexandra Colin
🔬 From JCB’s July issue (rupress.org/jcb/issue/22...): a PtK2 cell plated on a micropattern and injected with low doses of soluble actin (orange) and tubulin (blue) in order to generate speckles along the corresponding filaments. From @manuelthery.bsky.social group (rupress.org/jcb/article/...).
July 14, 2025 at 3:05 PM
🔬 From JCB’s July issue (rupress.org/jcb/issue/22...): a PtK2 cell plated on a micropattern and injected with low doses of soluble actin (orange) and tubulin (blue) in order to generate speckles along the corresponding filaments. From @manuelthery.bsky.social group (rupress.org/jcb/article/...).
Reposted by Alexandra Colin
this focused issue includes a great method by @alexandra-colin.bsky.social to make closed microwell in order to encapsulate your favorite reconstitution mix in compartments of controled size and shape. 🔴🟥🔻❤️
Interested in reconstitution methods? Love cell biology? Check out the accepted manuscripts in our Research Topic on Reconstitution Methods in Cell Biology! We are still open for submissions so if you're writing something exciting this summer, send it here: www.frontiersin.org/research-top...
Frontiers | Reconstitution Methods in Cell Biology
Reconstitution of cellular phenomena is a powerful approach for investigating the biochemical and biophysical processes that sustain life. Cell-free reconsti...
www.frontiersin.org
July 9, 2025 at 5:17 PM
this focused issue includes a great method by @alexandra-colin.bsky.social to make closed microwell in order to encapsulate your favorite reconstitution mix in compartments of controled size and shape. 🔴🟥🔻❤️
Reposted by Alexandra Colin
Interested in reconstitution methods? Love cell biology? Check out the accepted manuscripts in our Research Topic on Reconstitution Methods in Cell Biology! We are still open for submissions so if you're writing something exciting this summer, send it here: www.frontiersin.org/research-top...
Frontiers | Reconstitution Methods in Cell Biology
Reconstitution of cellular phenomena is a powerful approach for investigating the biochemical and biophysical processes that sustain life. Cell-free reconsti...
www.frontiersin.org
July 9, 2025 at 1:54 PM
Interested in reconstitution methods? Love cell biology? Check out the accepted manuscripts in our Research Topic on Reconstitution Methods in Cell Biology! We are still open for submissions so if you're writing something exciting this summer, send it here: www.frontiersin.org/research-top...
Reposted by Alexandra Colin
Want to brush up your French? Check the summary of our work with @stefvass.bsky.social, “Plongée au cœur de l'endocytose axonale”, just out in the June issue of Médecine/Science! Open access here: www.medecinesciences.org/fr/articles/...
And we got the cover 😎
And we got the cover 😎
July 8, 2025 at 9:09 AM
Want to brush up your French? Check the summary of our work with @stefvass.bsky.social, “Plongée au cœur de l'endocytose axonale”, just out in the June issue of Médecine/Science! Open access here: www.medecinesciences.org/fr/articles/...
And we got the cover 😎
And we got the cover 😎
Reposted by Alexandra Colin
Come and Join our Dpt in Beautiful #Geneva !
We are looking for a #Microscopy & #Image #Analysis expert to help all of us at the Dpt.
We are looking for a #Microscopy & #Image #Analysis expert to help all of us at the Dpt.
Hello microscopy and imaging experts and enthusiasts!
We are looking for a staff scientist to join us here in Geneva to work on microscopy and image analysis projects! See the link for the job announcement (in French and in English).
Please apply and/or repost!
jobs.unige.ch/www/wd_porta...
We are looking for a staff scientist to join us here in Geneva to work on microscopy and image analysis projects! See the link for the job announcement (in French and in English).
Please apply and/or repost!
jobs.unige.ch/www/wd_porta...
July 8, 2025 at 4:24 AM
Come and Join our Dpt in Beautiful #Geneva !
We are looking for a #Microscopy & #Image #Analysis expert to help all of us at the Dpt.
We are looking for a #Microscopy & #Image #Analysis expert to help all of us at the Dpt.
Reposted by Alexandra Colin
Registration and abstract submission for the 2025 SFP Physics & Life days are now open!
The meeting will be held on October 2-3 at the Institute Jacques Monod, Paris. Deadline: September 5.
phys-life-2025.sciencesconf.org?lang=en
@sfp-physique.bsky.social
@ijmonod.bsky.social
The meeting will be held on October 2-3 at the Institute Jacques Monod, Paris. Deadline: September 5.
phys-life-2025.sciencesconf.org?lang=en
@sfp-physique.bsky.social
@ijmonod.bsky.social
July 7, 2025 at 10:54 AM
Registration and abstract submission for the 2025 SFP Physics & Life days are now open!
The meeting will be held on October 2-3 at the Institute Jacques Monod, Paris. Deadline: September 5.
phys-life-2025.sciencesconf.org?lang=en
@sfp-physique.bsky.social
@ijmonod.bsky.social
The meeting will be held on October 2-3 at the Institute Jacques Monod, Paris. Deadline: September 5.
phys-life-2025.sciencesconf.org?lang=en
@sfp-physique.bsky.social
@ijmonod.bsky.social
Reposted by Alexandra Colin
One of the most exciting discoveries from our lab so far is now online as a preprint!
Read a story on how the ParMR and Min systems started to collaborate to create the CorMR cytoskeleton, which now controls cell shape in multicellular cyanobacteria:
www.biorxiv.org/content/10.1...
Read a story on how the ParMR and Min systems started to collaborate to create the CorMR cytoskeleton, which now controls cell shape in multicellular cyanobacteria:
www.biorxiv.org/content/10.1...
Evolutionary repurposing of a DNA segregation machinery into a cytoskeletal system controlling cyanobacterial cell shape
Bacteria, despite their diversity, use conserved cytoskeletal systems for their intracellular organization. In unicellular bacteria, the ParMRC DNA partitioning apparatus is well known for forming act...
www.biorxiv.org
July 2, 2025 at 11:35 AM
One of the most exciting discoveries from our lab so far is now online as a preprint!
Read a story on how the ParMR and Min systems started to collaborate to create the CorMR cytoskeleton, which now controls cell shape in multicellular cyanobacteria:
www.biorxiv.org/content/10.1...
Read a story on how the ParMR and Min systems started to collaborate to create the CorMR cytoskeleton, which now controls cell shape in multicellular cyanobacteria:
www.biorxiv.org/content/10.1...
Reposted by Alexandra Colin
Just out: we used SReD to measure the periodicity of spectrin rings along axons, finely capturing the effect of actin depolymerization. This and many more applications ➡️ www.nature.com/articles/s41...
Another great collab with @henriqueslab.bsky.social, congrats @afonsomendes92.bsky.social et al 🙏
Another great collab with @henriqueslab.bsky.social, congrats @afonsomendes92.bsky.social et al 🙏
July 2, 2025 at 12:20 PM
Just out: we used SReD to measure the periodicity of spectrin rings along axons, finely capturing the effect of actin depolymerization. This and many more applications ➡️ www.nature.com/articles/s41...
Another great collab with @henriqueslab.bsky.social, congrats @afonsomendes92.bsky.social et al 🙏
Another great collab with @henriqueslab.bsky.social, congrats @afonsomendes92.bsky.social et al 🙏
Reposted by Alexandra Colin
AML patient blasts exhibit polarization defects upon interaction with bone marrow stromal cells.
www.embopress.org/doi/full/10....
Work by Manuel Thery @manuelthery.bsky.social @institut-leucemie.bsky.social and co-workers.
www.embopress.org/doi/full/10....
Work by Manuel Thery @manuelthery.bsky.social @institut-leucemie.bsky.social and co-workers.
July 2, 2025 at 5:55 AM
AML patient blasts exhibit polarization defects upon interaction with bone marrow stromal cells.
www.embopress.org/doi/full/10....
Work by Manuel Thery @manuelthery.bsky.social @institut-leucemie.bsky.social and co-workers.
www.embopress.org/doi/full/10....
Work by Manuel Thery @manuelthery.bsky.social @institut-leucemie.bsky.social and co-workers.
Reposted by Alexandra Colin
Exciting news: our Board of Trustees has appointed @monicabettencourt.bsky.social as the CRG's new Director. Prof Bettencourt-Dias is expected to take up the post in 2026, replacing Dr. Luis Serrano, who will continue to maintain a research group at the institute.
www.crg.eu/en/news/moni...
www.crg.eu/en/news/moni...
July 1, 2025 at 8:59 AM
Exciting news: our Board of Trustees has appointed @monicabettencourt.bsky.social as the CRG's new Director. Prof Bettencourt-Dias is expected to take up the post in 2026, replacing Dr. Luis Serrano, who will continue to maintain a research group at the institute.
www.crg.eu/en/news/moni...
www.crg.eu/en/news/moni...
Reposted by Alexandra Colin
Les membres du Conseil scientifique de l'ENS-PSL partagent la vive inquiétude des personnels d'@universcience.bsky.social sur le devenir du @palaisdecouverte.bsky.social et s'associent à la pétition en cours.
En savoir plus 👉 https://bit.pulse.ly/b1pitkbaaa
En savoir plus 👉 https://bit.pulse.ly/b1pitkbaaa
June 26, 2025 at 2:59 PM
Les membres du Conseil scientifique de l'ENS-PSL partagent la vive inquiétude des personnels d'@universcience.bsky.social sur le devenir du @palaisdecouverte.bsky.social et s'associent à la pétition en cours.
En savoir plus 👉 https://bit.pulse.ly/b1pitkbaaa
En savoir plus 👉 https://bit.pulse.ly/b1pitkbaaa