Centre de Regulació Genòmica (CRG)
@crg.eu
Hola! We are the CRG, a research institute exploring the frontiers of biology in Barcelona. Som un centre CERCA. www.crg.eu
Reposted by Centre de Regulació Genòmica (CRG)
Last days to apply this position in our group! Do join us in this great Institute @crg.eu, with great colleagues, and help shaping the science and culture of our lab!
📣 Please spread: we’re hiring a Lab Manager! It is a critical position in our new lab. As our lab moves to Barcelona and joins the @crg.eu, we’re looking for a Lab Manager to help build the lab and set the lab atmosphere.
🔗 Apply here 👉 recruitment.crg.eu/content/jobs...
🔗 Apply here 👉 recruitment.crg.eu/content/jobs...
February 9, 2026 at 2:24 PM
Last days to apply this position in our group! Do join us in this great Institute @crg.eu, with great colleagues, and help shaping the science and culture of our lab!
This week is the International Day of Women and Girls in Science (11F) and we’re marking it with an open talk for anyone who’d like to join. Our guest is Sabrya Carim, who will share about her journey as a woman of colour navigating research, self-doubt, and the subtle pressures of belonging.
February 9, 2026 at 8:38 AM
This week is the International Day of Women and Girls in Science (11F) and we’re marking it with an open talk for anyone who’d like to join. Our guest is Sabrya Carim, who will share about her journey as a woman of colour navigating research, self-doubt, and the subtle pressures of belonging.
Happy 25th birthday to @icreacommunity.bsky.social, which has had a huge impact on making Catalonia a scientific powerhouse in the 21st century. This piece reminds us that investing in people is a powerful policy. Talent attracts talent, and entire research ecosystems grow around it.
The extraordinary league that attracts the world's best scientists to Catalonia
This initiative to attract and retain talent, a world first and which has inspired other international programs, has boosted our country's research system.
en.ara.cat
February 8, 2026 at 7:24 AM
Happy 25th birthday to @icreacommunity.bsky.social, which has had a huge impact on making Catalonia a scientific powerhouse in the 21st century. This piece reminds us that investing in people is a powerful policy. Talent attracts talent, and entire research ecosystems grow around it.
Orikine Bio, nacida en 2022 como spin-off del CRG, avanza en el desarrollo preclínico de sus fármacos para enfermedades autoinmunes y capta nuevos fondos de la entidad pública dependiente del Ministerio de Ciencia e Innovación
El CDTI invierte 2,7 millones de euros en Orikine Bio
Orikine Bio capta nuevos fondos con el objetivo de acelerar el desarrollo de fármacos para enfermedades autoinmunes. El CDTI, entidad pública dependiente del Ministerio de...
www.expansion.com
February 5, 2026 at 9:45 AM
Orikine Bio, nacida en 2022 como spin-off del CRG, avanza en el desarrollo preclínico de sus fármacos para enfermedades autoinmunes y capta nuevos fondos de la entidad pública dependiente del Ministerio de Ciencia e Innovación
Some of the most transformative companies began as a research insight that refused to stay inside a lab. That is why we created the CRG BioBusiness School, for life-science researchers who want to translate scientific results into tangible value. Apply by 1 March: www.crg.eu/en/event/crg...
February 4, 2026 at 11:25 AM
Some of the most transformative companies began as a research insight that refused to stay inside a lab. That is why we created the CRG BioBusiness School, for life-science researchers who want to translate scientific results into tangible value. Apply by 1 March: www.crg.eu/en/event/crg...
Reposted by Centre de Regulació Genòmica (CRG)
🧬 En 2024 Google se llevó un Nobel por AlphaFold, una IA para predecir proteínas. Ahora publica AlphaGenome, para leer el genoma. ¿Es esta IA tan rompedora?
🎙️ @lluismontoliu.bsky.social, Mafalda Dias de
@crg.eu, Beatriz López de @univgirona.bsky.social y Dido Carrero de @cniostopcancer.bsky.social
🎙️ @lluismontoliu.bsky.social, Mafalda Dias de
@crg.eu, Beatriz López de @univgirona.bsky.social y Dido Carrero de @cniostopcancer.bsky.social
¿Es la IA de Google que ayuda a leer el genoma una revolución digna de (otro) Nobel?
AlphaGenome predice el impacto de las variaciones en el ADN y puede ayudar a comprender enfermedades complejas. Otro modelo de Google DeepMind se llevó la medalla de oro sueca hace dos años, pero esta nueva IA tiene competencia y limitaciones
www.elconfidencial.com
February 1, 2026 at 9:21 PM
🧬 En 2024 Google se llevó un Nobel por AlphaFold, una IA para predecir proteínas. Ahora publica AlphaGenome, para leer el genoma. ¿Es esta IA tan rompedora?
🎙️ @lluismontoliu.bsky.social, Mafalda Dias de
@crg.eu, Beatriz López de @univgirona.bsky.social y Dido Carrero de @cniostopcancer.bsky.social
🎙️ @lluismontoliu.bsky.social, Mafalda Dias de
@crg.eu, Beatriz López de @univgirona.bsky.social y Dido Carrero de @cniostopcancer.bsky.social
Mafalda Dias, investigadora CRG, cree que el modelo es “un paso adelante" muy importante, pero: “son buenos para comprender qué pasa con la biología regulatoria, pero no son útiles para predecir si una variante entre personas distintas va a tener un impacto; tienen una utilidad clínica limitada."
Google logra predecir con su IA cómo una sola letra del genoma oscuro puede causar enfermedades
El modelo AlphaGenome de DeepMind ayuda a entender cómo gobierna nuestra biología el 98% del ADN, que una vez se consideró basura
elpais.com
January 28, 2026 at 5:09 PM
Mafalda Dias, investigadora CRG, cree que el modelo es “un paso adelante" muy importante, pero: “son buenos para comprender qué pasa con la biología regulatoria, pero no son útiles para predecir si una variante entre personas distintas va a tener un impacto; tienen una utilidad clínica limitada."
We have opened several exciting new positions across our research and administration. If you’re looking to grow your career and enjoy life by the Mediterranean, apply now: recruitment.crg.eu/content/jobs...
January 26, 2026 at 2:07 PM
We have opened several exciting new positions across our research and administration. If you’re looking to grow your career and enjoy life by the Mediterranean, apply now: recruitment.crg.eu/content/jobs...
Here's the official ranking:
January 23, 2026 at 7:29 AM
Here's the official ranking:
Investment in biotech saw a 60% boost last year, according to a joint analysis by Expansión and Biocat. Two CRG startups (Orikine and Seqera) are amongst the top twenty leading funding rounds last year. They are testimony of how publicly funded science can turn into real-world innovation.
Las 'start up' catalanas de salud logran más de 375 millones en rondas de inversión
El ecosistema catalán de empresas emergentes especializadas en el sector de la salud enfila un nuevo récord histórico en rondas de inversión. La financiación captada en...
www.expansion.com
January 23, 2026 at 7:28 AM
Investment in biotech saw a 60% boost last year, according to a joint analysis by Expansión and Biocat. Two CRG startups (Orikine and Seqera) are amongst the top twenty leading funding rounds last year. They are testimony of how publicly funded science can turn into real-world innovation.
We are deeply saddened by the passing of Peer Bork, who was a member of the CRG’s Scientific Advisory Board between Jan 2010 and Dec 2017. He played a key role in helping shape the institute’s scientific strategy. Our thoughts are with his family, friends and colleagues at @embl.org
In remembrance of Peer Bork | EMBL
EMBL and its community are deeply saddened by the death of Peer Bork, the organisation’s Interim Director General.
www.embl.org
January 21, 2026 at 8:34 AM
We are deeply saddened by the passing of Peer Bork, who was a member of the CRG’s Scientific Advisory Board between Jan 2010 and Dec 2017. He played a key role in helping shape the institute’s scientific strategy. Our thoughts are with his family, friends and colleagues at @embl.org
Conocer la variabilidad genética de todo el mundo acaba beneficiando a todo el mundo. Lo cuenta Michele Catanzaro en El Periódico después de que un estudio coliderado por @rodericguigo.bsky.social descubrió y cuantificó las lagunas en los mapas genéticos.
El sesgo europeo en los mapas genéticos entorpece la investigación biomédica
Los mapas de expresión de los genes están dominados por datos de individuos de ascendencia europea y presentan importantes lagunas de información sobre el resto del mundo
www.elperiodico.com
January 13, 2026 at 8:24 AM
Conocer la variabilidad genética de todo el mundo acaba beneficiando a todo el mundo. Lo cuenta Michele Catanzaro en El Periódico después de que un estudio coliderado por @rodericguigo.bsky.social descubrió y cuantificó las lagunas en los mapas genéticos.
Una buena noticia para empezar el año 😊 El trabajo liderado por @larsplus.bsky.social, investigador del CRG, ha sido reconocido por la Asociación Española contra el Cáncer como uno de los avances de investigación más destacados de 2025.
La investigación del cáncer en 2025 | Contra el Cáncer
Descubre los proyectos y avances clave en investigación contra el cáncer que cuentan con el apoyo de la Asociación Española Contra el Cáncer en 2025
blog.contraelcancer.es
January 12, 2026 at 8:56 AM
Una buena noticia para empezar el año 😊 El trabajo liderado por @larsplus.bsky.social, investigador del CRG, ha sido reconocido por la Asociación Española contra el Cáncer como uno de los avances de investigación más destacados de 2025.
Reposted by Centre de Regulació Genòmica (CRG)
What tools do we need to start engineering #aging and #longevity ? A🧵about something we've been cooking up in lab with Jeremy Vicencio at the @crg.eu : technology that lets us reach inside living animals and precisely dial multiple proteins' levels up and down. 1/10
December 16, 2025 at 12:09 PM
What tools do we need to start engineering #aging and #longevity ? A🧵about something we've been cooking up in lab with Jeremy Vicencio at the @crg.eu : technology that lets us reach inside living animals and precisely dial multiple proteins' levels up and down. 1/10
Hem estat seleccionats com a entitat beneficiària dels Projectes Singulars del Departament de Recerca i Universitats. Gràcies a aquest suport, desenvoluparem una infraestructura integral de microscòpia orientada a l’estudi avançat de mostres biològiques. #FEDERrecerca #FonsUEcat
December 16, 2025 at 10:10 AM
Hem estat seleccionats com a entitat beneficiària dels Projectes Singulars del Departament de Recerca i Universitats. Gràcies a aquest suport, desenvoluparem una infraestructura integral de microscòpia orientada a l’estudi avançat de mostres biològiques. #FEDERrecerca #FonsUEcat
The registration deadline for our course which integrates laboratory practice with computational training is approaching fast. You have until 15 December to sign up!
courses.crg.eu/events/decod...
courses.crg.eu/events/decod...
December 9, 2025 at 8:49 AM
The registration deadline for our course which integrates laboratory practice with computational training is approaching fast. You have until 15 December to sign up!
courses.crg.eu/events/decod...
courses.crg.eu/events/decod...
Big congrats to Sara Sdelci @sdelcilab.bsky.social for being as one of the 2025 @embo.org Young Investigators (YIPs), joining 28 outstanding early-career scientists recognised for excellence and originality in the life sciences. She is the eighth CRG scientist to join the prestigious programme!
December 3, 2025 at 7:18 PM
Big congrats to Sara Sdelci @sdelcilab.bsky.social for being as one of the 2025 @embo.org Young Investigators (YIPs), joining 28 outstanding early-career scientists recognised for excellence and originality in the life sciences. She is the eighth CRG scientist to join the prestigious programme!
Human gene maps contain major blind spots that leaves out a vast majority of the world's biological diversity, according to a new study led by the CRG's @rodericguigo.bsky.social with @bsc-cns.bsky.social. The researchers uncovered tens of thousands of new transcripts and entirely new genes.
Long-read transcriptomics of a diverse human cohort reveals ancestry bias in gene annotation - Nature Communications
Current human gene annotations are predominantly based on individuals of European ancestry. Here, the authors use long-read RNA sequencing across diverse human populations to reveal ancestry-specific ...
www.nature.com
December 3, 2025 at 1:38 PM
Human gene maps contain major blind spots that leaves out a vast majority of the world's biological diversity, according to a new study led by the CRG's @rodericguigo.bsky.social with @bsc-cns.bsky.social. The researchers uncovered tens of thousands of new transcripts and entirely new genes.
"Alucino cómo es posible que el orden de cuatro compuestos químicos esté determinando cómo se organiza un organismo, cómo se organiza el funcionamiento de las células, cómo cambian cuando se alteran en la enfermedad, cómo se organiza el cerebro para producir pensamientos. Todo, absolutamente todo."
Juan Valcárcel, biólogo molecular: “Cada uno de nosotros somos una experiencia única. ¿Qué sentido tiene clonarnos?”
“Una forma de vida sintética no se ha producido aún, que yo sepa, pero no hay ninguna razón por la que no se pueda producir”, dice el científico, premio Carmen y Severo Ochoa de Investigación
elpais.com
November 27, 2025 at 8:42 AM
"Alucino cómo es posible que el orden de cuatro compuestos químicos esté determinando cómo se organiza un organismo, cómo se organiza el funcionamiento de las células, cómo cambian cuando se alteran en la enfermedad, cómo se organiza el cerebro para producir pensamientos. Todo, absolutamente todo."
Transcription start sites are new mutational hotspots, according to a new study by the CRG's Donate Weghorn in Nature Communications. The mutations can be passed down to future generations and appear shortly after conception, in the first few rounds of cell division.
Transcription start sites experience a high influx of heritable variants fueled by early development - Nature Communications
The impact of transcription on germline mutagenesis remains poorly understood. Here, the authors identify a mutational hotspot at transcription start sites in the human germline that is significantly ...
www.nature.com
November 26, 2025 at 10:31 AM
Transcription start sites are new mutational hotspots, according to a new study by the CRG's Donate Weghorn in Nature Communications. The mutations can be passed down to future generations and appear shortly after conception, in the first few rounds of cell division.
Our annual PhD call is closing at the end of this week on 30 November. If you're interested in carrying out world-class scientific research in Barcelona, you still have a few days left to submit your application! www.crg.eu/en/content/t...
November 25, 2025 at 7:43 AM
Our annual PhD call is closing at the end of this week on 30 November. If you're interested in carrying out world-class scientific research in Barcelona, you still have a few days left to submit your application! www.crg.eu/en/content/t...
In today's @financialtimes.com: our researcher's efforts to use the diversity of life on Earth to see which parts of every one of the roughly 20,000 human proteins are essential for life and which can tolerate change, with the aim of supporting how doctors diagnose genetic disease.
New AI model enhances diagnosis of rare diseases
PopEVE system outperformed rivals such as Google DeepMind’s AlphaMissense
www.ft.com
November 24, 2025 at 10:39 AM
In today's @financialtimes.com: our researcher's efforts to use the diversity of life on Earth to see which parts of every one of the roughly 20,000 human proteins are essential for life and which can tolerate change, with the aim of supporting how doctors diagnose genetic disease.
Introducing popEVE, an AI model which can support diagnosing diseases "as rare as one". It was created by a team from the CRG and @harvardmed.bsky.social using data from hundreds of thousands of different species and of genetic variation across the human population.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Proteome-wide model for human disease genetics - Nature Genetics
popEVE is a proteome-wide deep generative model to identify and predict pathogenicity of missense mutations causing genetic disorders.
www.nature.com
November 24, 2025 at 10:37 AM
Introducing popEVE, an AI model which can support diagnosing diseases "as rare as one". It was created by a team from the CRG and @harvardmed.bsky.social using data from hundreds of thousands of different species and of genetic variation across the human population.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Centre de Regulació Genòmica (CRG)
Last call! Applications for the @crg.eu International PhD Programme 2025 in beautiful Barcelona close next week! Join us and our inspiring colleagues at the CRG - an exceptional environment for discovery, creativity, and scientific growth.
Apply here: www.crg.eu/en/content/t...
Apply here: www.crg.eu/en/content/t...
November 22, 2025 at 1:36 PM
Last call! Applications for the @crg.eu International PhD Programme 2025 in beautiful Barcelona close next week! Join us and our inspiring colleagues at the CRG - an exceptional environment for discovery, creativity, and scientific growth.
Apply here: www.crg.eu/en/content/t...
Apply here: www.crg.eu/en/content/t...
Considering a PhD in Barcelona? Have doubts about what the process entails? Join our experts online this Thursday who can answer your questions, big and small. More info about our 20+ fully-funded positions here: www.crg.eu/en/content/t...
November 18, 2025 at 11:01 AM
Considering a PhD in Barcelona? Have doubts about what the process entails? Join our experts online this Thursday who can answer your questions, big and small. More info about our 20+ fully-funded positions here: www.crg.eu/en/content/t...