Alberto Docampo Seara
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albertodseara.bsky.social
Alberto Docampo Seara
@albertodseara.bsky.social
140 followers 86 following 14 posts
Interested in development and regeneration of the central nervous system. PostDoc studying spinal cord regeneration in @beckergroup.bsky.social 😊

ORCID: 0000-0001-8711-6230
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albertodseara.bsky.social
Alberto Docampo Seara @albertodseara.bsky.social · Nov 18
Very happy to share my first preprint as a postdoc in the Becker Lab 🥳 If you are interested in cell-cell interactions during spinal cord regeneration feel free to have a look 😊 #spinalcord #regeneration #zebrafish
www.biorxiv.org/content/10.1...
Macrophage crosstalk with neural progenitors and fibroblasts controls regenerative neurogenesis via Sema4ab after spinal cord injury in zebrafish
After spinal cord injury, interactions of multiple tissues inhibit neuronal regeneration in mammals, but not in anamniotes, such as zebrafish. These pivotal interactions are poorly understood. Here we...
www.biorxiv.org
Reposted by Alberto Docampo Seara
cagricevrim.bsky.social
I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵
Induction of menstruation in mice reveals the regulation of menstrual shedding
During menstruation, an inner layer of the endometrium is selectively shed, while an outer, progenitor-containing layer is preserved to support repeated regeneration. Progress in understanding this co...
www.biorxiv.org
October 10, 2025 at 12:50 PM
Reposted by Alberto Docampo Seara
dev-journal.bsky.social
📢Call for papers. Submit your latest research to our upcoming special issue – The Extracellular Environment in Development, Regeneration and Stem Cells

Guest Editors: Alex Hughes and Rashmi Priya

📅 Deadline: 1 March 2026

journals.biologists.com/dev/pages/ex...

#DevBio
September 1, 2025 at 12:29 PM
Reposted by Alberto Docampo Seara
crtd-tud.bsky.social
🥳 Congratulations to our postdoc, Dr. Anna Czarkwiani @aniaczark.bsky.social, on receiving the ERC Starting Grant @erc.europa.eu!

With €2 million in funding, Anna will explore the biology of gravisensation and uncover insights into related disorders. 🧠

#CMCBnews @tudresden.bsky.social #ERCStG
September 4, 2025 at 10:13 AM
Reposted by Alberto Docampo Seara
sierralab.bsky.social
🧠🧪Funded PhD job offer ok neddylation in glial cells @achucarro.bsky.social

Pls repost
September 4, 2025 at 3:10 PM
Reposted by Alberto Docampo Seara
idoiaeu.bsky.social
🧠🦈Excited to present our latest work🧠🦈Interested in brain evolution? And shark embryos? Then read on… Our work sheds light on the deep origins of our brain’s most complex regions.
September 2, 2025 at 5:51 PM
albertodseara.bsky.social
Zebrafish larvae are really good for time lapses. Just take some popcorns enjoy them like if they were movies. Here you can see with your own eyes how immune cells divide. This one I call it "Divide and flee" #spinalcordregeneration #zebrafish #timelapse #microglia
August 14, 2025 at 11:19 AM
Reposted by Alberto Docampo Seara
clark-lab-retina.bsky.social
Our work on the TET enzymes in retinal development is out. We identified that rod fate is inhibited when DNA demethylation is prevented by removal of the TET enzymes. Interestingly, photoreceptor numbers are normal. We utilized WGBS and bACE-seq to profile the precise localization of 5mC and 5hmC,…
plosbiology.org PLOS Biology @plosbiology.org · Aug 5
TET enzymes remove #DNAmethylation markers; @ismaelhdeznunez.bsky.social @clark-lab-retina.bsky.social &co show that these enzymes are required for #photoreceptor cells to initiate the genetic program to become rods instead of cones, & for maturation of the #retina @plosbiology.org 🧪 plos.io/3UaVBfl
Left: The active DNA methylation cycle. (i) 5mC is added by DNMTs. (ii) The TET enzymes oxidize 5mC to 5hmC. (iii) 5hmC is converted to 5fC and 5caC by the TET enzymes, followed by conversion back to cytosine by TDG and the base-excision repair pathway. (iv) Alternatively, APOBEC converts 5mC to thymine, causing DNA mismatch. Right: H&E staining of an allelic series of TET conditional P21 mutants.
August 6, 2025 at 3:19 AM
Reposted by Alberto Docampo Seara
ebablab.bsky.social
🚨Anyone want a job?🚨
We have two #postdocs up for grabs! 🧪
- cell developmental biology/#evodevo/#neuroevodevo
- bioinformatics and molecular biology
Both working on brain evolution in Heliconiini butterflies
Details below! Please repost 🙏 1/n
June 4, 2025 at 9:51 AM
albertodseara.bsky.social
One long standing question answered ✅
Beautiful science ✅
Cool model organism ✅
Congratulations to the authors!
leootsuki.bsky.social Leo Otsuki @leootsuki.bsky.social · May 21
Delighted that our work on positional memory is now published. We asked how axolotl cells 'know' which part of the limb to regenerate after injury.
www.nature.com/articles/s41...
A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka.
🧵1/14
May 23, 2025 at 2:48 PM
Reposted by Alberto Docampo Seara
zebrafishrock.bsky.social
Useful tips from @scekker.bsky.social et al. 🐟
May 15, 2025 at 7:41 PM
Reposted by Alberto Docampo Seara
biologyopen.bsky.social
African turquoise killifish are short-lived & their CNS exhibits human-like ageing. Zandecki @eveseuntjens.bsky.social & co reveal the cellular diversity during the explosive growth of the telencephalon, uncovering specific progenitor signatures for each neurogenic region. 🧠 doi.org/10.1242/bio....
Progenitor heterogeneity in the developing telencephalon. A multi-panelled figure showing different progenitor cells in different areas of the developing telencephalon of the killifish. HCR-FISH targeting CX43 (pan Astro-RG, magenta) and ZIC2 (NE-RG, yellow) (A) or NGPmix (turquoise) (B), is combined with immunohistochemical staining for the proliferation marker PCNA (white). NGPs account for the bulk of proliferation; Astro-RGs and NE-RGs appear both dividing and non-dividing depending on the location in the telencephalon. (C-E) Magnifications of the regions in the boxes in A and B. Non-dividing Astro-RGs (CX43+, PCNA−) are indicated with a magenta arrowhead and appear isolated in between stretches of dividing NGPs. (F) Illustration of a 5 dph coronal telencephalic section at mid-anterior-posterior level. The distribution of dividing and non-dividing Astro-RGs, NE-RGs and NGPs is displayed in the ventricular zone.
May 15, 2025 at 1:02 PM
Reposted by Alberto Docampo Seara
simoesfilipa.bsky.social
🫀Job alert 🧬 come and be our colleague! Join a BBSRC-funded consortium aiming to understand how the human heart develops - you will be contributing multimodal single cell & spatial transcriptomics data using zebrafish and human cardiac organoids as models. Learn more: www.heartdevelopment.org (1/4)
CellTalk HHD | Human Heart Development Research
CellTalk-Human Heart Development is a BBSRC funded consortium established to find out more about how cells come together to build the heart as it grows inside the womb.
www.heartdevelopment.org
May 16, 2025 at 10:10 AM
Reposted by Alberto Docampo Seara
abeisaw.bsky.social
Are you interested in how cells talk to each other to promote regeneration in the heart?

@bailinwu.bsky.social @florian-constanty.bsky.social and I are and we wrote a review about it ❤️🐟🐭

Check it out here 👇

www.sciencedirect.com/science/arti...
Cardiac regeneration: Unraveling the complex network of intercellular crosstalk
The heart is composed of multiple cell types, including cardiomyocytes, endothelial/endocardial cells, fibroblasts, resident immune cells and epicardi…
www.sciencedirect.com
May 13, 2025 at 2:33 PM
Reposted by Alberto Docampo Seara
uwiscrm.bsky.social
Researchers in the Reh Lab have produced the clearest evidence yet that AAV-delivered genes can stimulate regeneration in the mammalian retina. @tomreh.bsky.social Marina Pavlou. #retina #regeneration @uwmedicine.bsky.social

shorturl.at/qVUKz
Regenerating Retinal Neurons using AAV Vectors / ISCRM
.
shorturl.at
March 26, 2025 at 8:27 PM
albertodseara.bsky.social
This afternoon 👇🏻
isrbio.bsky.social International Society for Regenerative Biology @isrbio.bsky.social · May 13
Happening Today!🚨ISRB Webinar Alert - Zone 2: Europe, West Asia, Africa 📷 Join us on May 13th at 4pm Central European Time. Featuring @albertodseara.bsky.social
May 13, 2025 at 10:47 AM
Reposted by Alberto Docampo Seara
eveseuntjens.bsky.social
Now you can also read all about @idoiaeu.bsky.social beautiful work on catshark brain development and the enigmatic origin of cajal retzius cells in their preprint www.biorxiv.org/content/10.1...
May 9, 2025 at 5:36 AM
Reposted by Alberto Docampo Seara
sengulesra.bsky.social
Excited to share our preprint! We show that sustained macrophage and B cell responses are essential for heart regeneration in Mexican cavefish, helping uncover why surface fish heal but cavefish scar 🫀🐟. Check out the full story:
www.biorxiv.org/content/10.1...
Absence of a prolonged macrophage and B cell response inhibits heart regeneration in the Mexican cavefish
A balanced immune response after cardiac injury is crucial to successful heart regeneration, but knowledge of what distinguishes a regenerative from a scarring response is still limited. The Mexican c...
www.biorxiv.org
May 2, 2025 at 6:17 PM
albertodseara.bsky.social
The next 13th of May I’ll be taking about microglia in spinal cord regeneration. If you’re interested 👇🏻👇🏻
isrbio.bsky.social International Society for Regenerative Biology @isrbio.bsky.social · Apr 29
🚨ISRB Webinar Alert - Zone 2: Europe, West Asia, Africa 📷 Join us on May 13th at 4pm Central European Time. Featuring Alberto Docampo Seara.
April 29, 2025 at 10:06 PM
Reposted by Alberto Docampo Seara
royalsocietypublishing.org
Exacerbated sonic hedgehog signalling promotes a transition from chemical pre-patterning of chicken reticulate scales to mechanical skin folding: royalsocietypublishing.org/doi/10.1098/... @lanevol.bsky.social‬ @rorylcooper.bsky.social‬ #OpenBiology #DevBio #biophysics
April 28, 2025 at 7:03 PM
Reposted by Alberto Docampo Seara
abeisaw.bsky.social
Very excited to see the first Beisaw lab publication out in its final form 🥳🥳 rdcu.be/ei1I7 if you’re interested in zebrafish heart regeneration and how cardiomyocytes replace the fibrotic injured tissue (spoiler alert: macrophages play an important role), then read it here 👇
Border-zone cardiomyocytes and macrophages regulate extracellular matrix remodeling to promote cardiomyocyte protrusion during cardiac regeneration
Nature Communications - Adult zebrafish are capable of heart regeneration, but how the collagenous injury site is replaced remains unclear. Here they provide an in-depth analysis of cardiomyocyte...
rdcu.be
April 23, 2025 at 5:53 PM
Reposted by Alberto Docampo Seara
tatianasg.bsky.social
It has been known for a long time that if the starting point of limb regeneration is at the hand level or close to the shoulder, it would take about the same time to regenerate. Puzzling right?
Check out this preprint from our lab to know more about it:
www.biorxiv.org/content/10.1...
Mechanical control of tissue growth during limb regeneration
The axolotl is a highly regenerative species, capable of restoring full limbs, regardless of the amputation site. However, the regeneration rate is adjusted with the plane of amputation along the prox...
www.biorxiv.org
April 14, 2025 at 1:06 PM
Reposted by Alberto Docampo Seara
mancusorenzo.bsky.social
I am so excited to share our review on microglial heterogeneity @natureneuro.bsky.social! It was a fantastic effort by the lab, led by @c9laura72.bsky.social and Alma Mohebiany. We provide a critical view on the plethora of microglial cell states in health and disease. www.nature.com/articles/s41...
Microglia heterogeneity, modeling and cell-state annotation in development and neurodegeneration - Nature Neuroscience
Microglia have key roles in CNS development and neurodegeneration. Here, the authors provide an overview of microglia heterogeneity, cell-state annotation and model systems.
www.nature.com
April 7, 2025 at 3:59 PM
Reposted by Alberto Docampo Seara
vabraira.bsky.social
Please register for this amazing meeting! Applications for this meeting must be submitted by June 8, 2025
March 20, 2025 at 4:18 PM
Reposted by Alberto Docampo Seara
plosbiology.org
Creating an asymmetric heart: @tbonnely.bsky.social @audreydsg.bsky.social @meilhacsigolene.bsky.social &co identify Notch3 as a novel asymmetric factor in lateral plate mesoderm that acts as a genetic modifier of NODAL to regulate heart morphogenesis @plosbiology.org 🧪 plos.io/42q6H4L
Left: Expression of Notch3 (white) detected by whole mount RNAscope ISH in an E8.5d wild-type embryo, shown in frontal views (top, cranial part of the embryo) and transverse section (bottom). Filled and empty arrowheads point to high and low expression, respectively. Right: Segmentation of the cardiac region in 3D images, to quantify gene expression in the left (white) or right (yellow) heart field. The heart tube is colored in red. Somites are outlined by white dotted lines. Expression of Notch3 within the segmented second heart field is extracted in the right panel.
April 1, 2025 at 1:39 PM