Amanda Sierra
@sierralab.bsky.social
Research professor at Achucarro Basque Center for Neuroscience. Microglial lover, passionate about science outreach.
ORCID: 0000-0001-8415-096X
Lab website: https://www.achucarro.org/es/laboratory/glial-cell-biology/
ORCID: 0000-0001-8415-096X
Lab website: https://www.achucarro.org/es/laboratory/glial-cell-biology/
Pinned
Amanda Sierra
@sierralab.bsky.social
· Dec 11
Happy to share our Perspective on #microglia #pruning and help to answer the questions of whether they are hunters or gatherers of brain #synapses 🧠🧪
#neuroskyence
nature.com/articles/s4159…
#neuroskyence
nature.com/articles/s4159…
September 4, 2025 at 3:10 PM
Join us if you want to learn about #microglia!
🗓️El próximo 16 de septiembre a las 16h "Webinar Grupo Neurobiología Molecular" coordinado por @pgonzalezrodriguez.bsky.social
🗣️ @sierralab.bsky.social “Brain scavengers: microglial phagocytosis in health and disease
✍️ https://f.mtr.cool/fawelesych
🗣️ @sierralab.bsky.social “Brain scavengers: microglial phagocytosis in health and disease
✍️ https://f.mtr.cool/fawelesych
August 13, 2025 at 10:39 PM
Join us if you want to learn about #microglia!
"Sisterly love"
Proliferating neural stem cells🧪🧠
Proliferating neural stem cells🧪🧠
August 8, 2025 at 9:05 AM
"Sisterly love"
Proliferating neural stem cells🧪🧠
Proliferating neural stem cells🧪🧠
Are you interested in human brain #organoids to study #microglia but don't know where to start?🧠🧪
#neuroskyence
Here's our piece of advice on "Building Immunocompetent Cerebral Organoids From a Developmental Perspective"
onlinelibrary.wiley.com/doi/10.1002/...
#neuroskyence
Here's our piece of advice on "Building Immunocompetent Cerebral Organoids From a Developmental Perspective"
onlinelibrary.wiley.com/doi/10.1002/...
Building Immunocompetent Cerebral Organoids From a Developmental Perspective
Conventional cerebral organoids do not contain microglia, which must be added.
We propose recommendations to assess microglial immunocompetence using quantitative approaches and stringent statist...
onlinelibrary.wiley.com
July 24, 2025 at 7:19 AM
Are you interested in human brain #organoids to study #microglia but don't know where to start?🧠🧪
#neuroskyence
Here's our piece of advice on "Building Immunocompetent Cerebral Organoids From a Developmental Perspective"
onlinelibrary.wiley.com/doi/10.1002/...
#neuroskyence
Here's our piece of advice on "Building Immunocompetent Cerebral Organoids From a Developmental Perspective"
onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Amanda Sierra
The @sierralab.bsky.social lab is hiring!
Postdoctoral position in #microglial development (#IKUR)
www.achucarro.org/job/postdoct...
Postdoctoral position in #microglial development (#IKUR)
www.achucarro.org/job/postdoct...
July 14, 2025 at 9:57 AM
The @sierralab.bsky.social lab is hiring!
Postdoctoral position in #microglial development (#IKUR)
www.achucarro.org/job/postdoct...
Postdoctoral position in #microglial development (#IKUR)
www.achucarro.org/job/postdoct...
Reaching Marseille was quite an odissey because of the wildfires, but the #Euroglia meeting was quite a success! Tons of science, friends and fun!
July 11, 2025 at 7:51 AM
Reaching Marseille was quite an odissey because of the wildfires, but the #Euroglia meeting was quite a success! Tons of science, friends and fun!
Reposted by Amanda Sierra
@sierralab.bsky.social reflexiona sobre si se puede parar la #menopausia
www.elcorreo.com/vivir/salud/...
www.elcorreo.com/vivir/salud/...
¿Y si pudiéramos evitar la menopausia? | El Correo
Se están desarrollando terapias para rejuvenecer los ovarios y evitar los efectos negativos sobre la salud
www.elcorreo.com
June 2, 2025 at 7:03 PM
@sierralab.bsky.social reflexiona sobre si se puede parar la #menopausia
www.elcorreo.com/vivir/salud/...
www.elcorreo.com/vivir/salud/...
This sounds sooo familiar
So, maybe, "The next time we hear a crazy/bitch narrative about a senior woman, let's ask ourselves: How much first-hand evidence do we personally have to back it up -- does it resonate with our own direct observations and interactions with her?"
So, maybe, "The next time we hear a crazy/bitch narrative about a senior woman, let's ask ourselves: How much first-hand evidence do we personally have to back it up -- does it resonate with our own direct observations and interactions with her?"
“How might the narrative about senior women be challenged or changed in order to respect these women who have achieved enough success to earn promotion? How do we stop this generational cycle so that women's wings aren't clipped as soon as they approach the power to soar.”
May 4, 2025 at 9:22 AM
This sounds sooo familiar
So, maybe, "The next time we hear a crazy/bitch narrative about a senior woman, let's ask ourselves: How much first-hand evidence do we personally have to back it up -- does it resonate with our own direct observations and interactions with her?"
So, maybe, "The next time we hear a crazy/bitch narrative about a senior woman, let's ask ourselves: How much first-hand evidence do we personally have to back it up -- does it resonate with our own direct observations and interactions with her?"
Reposted by Amanda Sierra
#Cellpose 3 paper now out. Not all images are perfect. Restore your images with Cellpose3 to get better segmentations, w/ @marius10p.bsky.social www.nature.com/articles/s41...
February 12, 2025 at 11:10 AM
#Cellpose 3 paper now out. Not all images are perfect. Restore your images with Cellpose3 to get better segmentations, w/ @marius10p.bsky.social www.nature.com/articles/s41...
Reposted by Amanda Sierra
Even in the absence of formal instruction to do so, we should continue to hold ourselves and our neuroscience colleagues accountable for “Sex as a Biological Variable” practices, writes @docbecca.bsky.social.
#neuroskyence
www.thetransmitter.org/sex-differen...
#neuroskyence
www.thetransmitter.org/sex-differen...
Amid NIH upheaval, how to keep sex as a biological variable
Even in the absence of formal instruction to do so, we should continue to hold our colleagues accountable for SABV practices.
www.thetransmitter.org
March 25, 2025 at 1:54 PM
Even in the absence of formal instruction to do so, we should continue to hold ourselves and our neuroscience colleagues accountable for “Sex as a Biological Variable” practices, writes @docbecca.bsky.social.
#neuroskyence
www.thetransmitter.org/sex-differen...
#neuroskyence
www.thetransmitter.org/sex-differen...
Reposted by Amanda Sierra
Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter
www.nytimes.com/2025/03/01/u...
www.nytimes.com/2025/03/01/u...
March 1, 2025 at 6:07 PM
Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter
www.nytimes.com/2025/03/01/u...
www.nytimes.com/2025/03/01/u...
Reposted by Amanda Sierra
🗣️ℹ️How do we prevent misinformation? By talking about it, without reservations and full openness.
🧫🐁It is the same with science communication and #AnimalResearch specifically.
💉💡Even if you somehow oppose it… know why it is still needed.
🧫🐁It is the same with science communication and #AnimalResearch specifically.
💉💡Even if you somehow oppose it… know why it is still needed.
📄 We have updated our popular website information page '40 reasons why animals are needed for #BiomedicalResearch'.
🔬 The page which presents compelling reasons why #AnimalResearch continues to be essential in medical advances & scientific discovery.
www.eara.eu/post/40-reas...
🔬 The page which presents compelling reasons why #AnimalResearch continues to be essential in medical advances & scientific discovery.
www.eara.eu/post/40-reas...
40 reasons why animals are needed – updated EARA page
EARA has updated its popular website information page 40 reasons why animals are needed for biomedical research, which presents compelling reasons, in bitesize form, why the use of animals continues t...
www.eara.eu
February 25, 2025 at 11:07 PM
🗣️ℹ️How do we prevent misinformation? By talking about it, without reservations and full openness.
🧫🐁It is the same with science communication and #AnimalResearch specifically.
💉💡Even if you somehow oppose it… know why it is still needed.
🧫🐁It is the same with science communication and #AnimalResearch specifically.
💉💡Even if you somehow oppose it… know why it is still needed.
Reposted by Amanda Sierra
This is today. No recording, so it won't be available in our website.
Don't miss it!
Don't miss it!
📢New webinar coming soon📢
Dr. Gilbert Di Paolo from Denali Therapeutics will be our next speaker on February 4th. Check all the information in the flyer and add it to your calendar!
Dr. Gilbert Di Paolo from Denali Therapeutics will be our next speaker on February 4th. Check all the information in the flyer and add it to your calendar!
February 4, 2025 at 11:59 AM
This is today. No recording, so it won't be available in our website.
Don't miss it!
Don't miss it!
Reposted by Amanda Sierra
I would love to hear your views on this article. I discuss some hurdles I faced when thinking about experiments and projects design. This is something no one formally teaches you.
network.febs.org/posts/thinki...
network.febs.org/posts/thinki...
Thinking like a scientist: not that trivial
network.febs.org
January 31, 2025 at 9:26 AM
I would love to hear your views on this article. I discuss some hurdles I faced when thinking about experiments and projects design. This is something no one formally teaches you.
network.febs.org/posts/thinki...
network.febs.org/posts/thinki...
🧪🧠
#GliaPapers #GliaFebruary2025 RESEARCH
Noelia Rodriguez-Iglesias, …, Simon Gutbier,
@sierralab.bsky.social
Bottom-up approach identifies antipsychotic & antineoplastic trifluoperazine & ribose derivative deoxytubercidin as microglial phagocytosis inhibitors onlinelibrary.wiley.com/doi/10.1002/...
Noelia Rodriguez-Iglesias, …, Simon Gutbier,
@sierralab.bsky.social
Bottom-up approach identifies antipsychotic & antineoplastic trifluoperazine & ribose derivative deoxytubercidin as microglial phagocytosis inhibitors onlinelibrary.wiley.com/doi/10.1002/...
February 2, 2025 at 3:56 PM
🧪🧠
Reposted by Amanda Sierra
Interested in pursuing a PhD in neuroimmunology and metabolism? Apply to this call to work on a collaborative project between my group and @cmadore.bsky.social !
🧠Talented future PhD students in Neuroscience/Nutrition !!! Do not hesitate to apply to this great PhD program at Bordeaux University🧠
(the call ends soon)
🧠🤯🧪
www.bordeaux-neurocampus.fr/phd-call-2025/
(the call ends soon)
🧠🤯🧪
www.bordeaux-neurocampus.fr/phd-call-2025/
Neurocampus PhD program - Call for applications - Bordeaux Neurocampus
Applications are open until 28th February 2025.
www.bordeaux-neurocampus.fr
January 30, 2025 at 10:54 AM
Interested in pursuing a PhD in neuroimmunology and metabolism? Apply to this call to work on a collaborative project between my group and @cmadore.bsky.social !
"The human mind is not, like ChatGPT a lumbering statistical engine for pattern matching, gorging on terabytes of data and extrapolating the most likely conversational response, most probable answer to a scientific question"
Noam Chomsky: The False Promise of ChatGPT www.nytimes.com/2023/03/08/o...
Noam Chomsky: The False Promise of ChatGPT www.nytimes.com/2023/03/08/o...
Opinion | Noam Chomsky: The False Promise of ChatGPT (Published 2023)
The most prominent strain of A.I. encodes a flawed conception of language and knowledge.
www.nytimes.com
January 29, 2025 at 7:08 AM
"The human mind is not, like ChatGPT a lumbering statistical engine for pattern matching, gorging on terabytes of data and extrapolating the most likely conversational response, most probable answer to a scientific question"
Noam Chomsky: The False Promise of ChatGPT www.nytimes.com/2023/03/08/o...
Noam Chomsky: The False Promise of ChatGPT www.nytimes.com/2023/03/08/o...
Reposted by Amanda Sierra
📢New webinar coming soon📢
Dr. Gilbert Di Paolo from Denali Therapeutics will be our next speaker on February 4th. Check all the information in the flyer and add it to your calendar!
Dr. Gilbert Di Paolo from Denali Therapeutics will be our next speaker on February 4th. Check all the information in the flyer and add it to your calendar!
January 28, 2025 at 10:48 AM
📢New webinar coming soon📢
Dr. Gilbert Di Paolo from Denali Therapeutics will be our next speaker on February 4th. Check all the information in the flyer and add it to your calendar!
Dr. Gilbert Di Paolo from Denali Therapeutics will be our next speaker on February 4th. Check all the information in the flyer and add it to your calendar!
Contact me if you are interested in pursuing an independent position in Neuroscience 🧪🧠 at Achucarro @achucarro.bsky.social
calls.ikerbasque.net
calls.ikerbasque.net
January 16, 2025 at 2:55 PM
Contact me if you are interested in pursuing an independent position in Neuroscience 🧪🧠 at Achucarro @achucarro.bsky.social
calls.ikerbasque.net
calls.ikerbasque.net
Any #SpatialTranscriptomics people out there interested in studying #microglial development?
We need a collaborator based in the Americas or Asia to apply for a #HSPF grant
www.hfsp.org/funding/hfsp...
We need a collaborator based in the Americas or Asia to apply for a #HSPF grant
www.hfsp.org/funding/hfsp...
Research Grants | Human Frontier Science Program
www.hfsp.org
January 15, 2025 at 11:38 AM
Any #SpatialTranscriptomics people out there interested in studying #microglial development?
We need a collaborator based in the Americas or Asia to apply for a #HSPF grant
www.hfsp.org/funding/hfsp...
We need a collaborator based in the Americas or Asia to apply for a #HSPF grant
www.hfsp.org/funding/hfsp...
Reposted by Amanda Sierra
“‘It’s very easy to assume that science is going to change organically towards equality — and what this study shows is that that’s not happening…It is an ‘important reminder for us that we need to stay vigilant in working towards equality in science’” @crsugimoto.bsky.social 🧪
#AcademicSky 👩🏽🔬
#AcademicSky 👩🏽🔬
Who’s quitting academia? Data reveal gender gaps in surprising fields
Even in scientific areas in which women are well represented, they are up to 40% more likely than men to leave research within 20 years.
www.nature.com
January 12, 2025 at 3:54 PM
“‘It’s very easy to assume that science is going to change organically towards equality — and what this study shows is that that’s not happening…It is an ‘important reminder for us that we need to stay vigilant in working towards equality in science’” @crsugimoto.bsky.social 🧪
#AcademicSky 👩🏽🔬
#AcademicSky 👩🏽🔬
I think the field needs to reconsider the widespread concept that microglia are The most important factor controlling synaptic pruning.🧠🧪
We offered our Perspective on whether they are hunters or gatherers of synaptic debris here
www.nature.com/articles/s41...
We offered our Perspective on whether they are hunters or gatherers of synaptic debris here
www.nature.com/articles/s41...
January 8, 2025 at 8:58 AM
I think the field needs to reconsider the widespread concept that microglia are The most important factor controlling synaptic pruning.🧠🧪
We offered our Perspective on whether they are hunters or gatherers of synaptic debris here
www.nature.com/articles/s41...
We offered our Perspective on whether they are hunters or gatherers of synaptic debris here
www.nature.com/articles/s41...
Happy to share our Perspective on #microglia #pruning and help to answer the questions of whether they are hunters or gatherers of brain #synapses 🧠🧪
#neuroskyence
nature.com/articles/s4159…
#neuroskyence
nature.com/articles/s4159…
December 11, 2024 at 3:37 PM
Happy to share our Perspective on #microglia #pruning and help to answer the questions of whether they are hunters or gatherers of brain #synapses 🧠🧪
#neuroskyence
nature.com/articles/s4159…
#neuroskyence
nature.com/articles/s4159…
The call is now open!
Junior postdocs deadline: Jan 17
Senior postdocs deadline: Jan 21
Junior postdocs deadline: Jan 17
Senior postdocs deadline: Jan 21
#Microglia lovers, winter is coming and along will come the #JuanDeLaCierva and #RamonyCajal calls for junior and senior postdocs!
DM or email me if you are interested in learning how risk genes for neurodegenerative diseases affect microglial early development.
DM or email me if you are interested in learning how risk genes for neurodegenerative diseases affect microglial early development.
December 9, 2024 at 11:46 AM
The call is now open!
Junior postdocs deadline: Jan 17
Senior postdocs deadline: Jan 21
Junior postdocs deadline: Jan 17
Senior postdocs deadline: Jan 21